AP2004003186A0 - Bicyclic amino acids as pharmaceutical agents. - Google Patents

Bicyclic amino acids as pharmaceutical agents.

Info

Publication number
AP2004003186A0
AP2004003186A0 AP2004003186A AP2004003186A AP2004003186A0 AP 2004003186 A0 AP2004003186 A0 AP 2004003186A0 AP 2004003186 A AP2004003186 A AP 2004003186A AP 2004003186 A AP2004003186 A AP 2004003186A AP 2004003186 A0 AP2004003186 A0 AP 2004003186A0
Authority
AP
ARIPO
Prior art keywords
amino acids
pharmaceutical agents
bicyclic amino
bicyclic
pharmaceutical
Prior art date
Application number
AP2004003186A
Other languages
English (en)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of AP2004003186A0 publication Critical patent/AP2004003186A0/xx

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/20—All rings being cycloaliphatic the ring system containing seven carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/22—All rings being cycloaliphatic the ring system containing eight carbon atoms, e.g. pentalene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
    • C07C2602/28—Hydrogenated naphthalenes
AP2004003186A 1999-10-20 2000-10-17 Bicyclic amino acids as pharmaceutical agents. AP2004003186A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16072599P 1999-10-20 1999-10-20
PCT/US2000/028687 WO2001028978A1 (en) 1999-10-20 2000-10-17 Bicyclic amino acids as pharmaceutical agents

Publications (1)

Publication Number Publication Date
AP2004003186A0 true AP2004003186A0 (en) 2004-12-31

Family

ID=22578159

Family Applications (2)

Application Number Title Priority Date Filing Date
APAP/P/2002/002517A AP2002002517A0 (en) 1999-10-20 2000-10-17 Bicyclic amino acids as pharmaceutical agents.
AP2004003186A AP2004003186A0 (en) 1999-10-20 2000-10-17 Bicyclic amino acids as pharmaceutical agents.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
APAP/P/2002/002517A AP2002002517A0 (en) 1999-10-20 2000-10-17 Bicyclic amino acids as pharmaceutical agents.

Country Status (50)

Country Link
US (2) US6689906B1 (xx)
EP (2) EP1506955B1 (xx)
JP (2) JP3632191B2 (xx)
KR (2) KR100566462B1 (xx)
CN (1) CN1165518C (xx)
AP (2) AP2002002517A0 (xx)
AR (2) AR026087A1 (xx)
AT (2) ATE358116T1 (xx)
AU (2) AU778871B2 (xx)
BG (2) BG108860A (xx)
BR (1) BR0014972B1 (xx)
CA (1) CA2386297C (xx)
CO (1) CO5280060A1 (xx)
CR (1) CR6620A (xx)
CU (1) CU23112A3 (xx)
CZ (1) CZ295960B6 (xx)
DE (2) DE60019628T2 (xx)
DO (1) DOP2000000083A (xx)
DZ (1) DZ3197A1 (xx)
EA (1) EA005206B1 (xx)
EC (1) ECSP045393A (xx)
EE (1) EE200200211A (xx)
ES (2) ES2282785T3 (xx)
GE (1) GEP20043297B (xx)
GT (2) GT200000183AA (xx)
HK (1) HK1049826B (xx)
HN (1) HN2000000224A (xx)
HR (2) HRP20020428B1 (xx)
HU (1) HUP0203325A3 (xx)
IL (3) IL149143A0 (xx)
IS (2) IS6348A (xx)
MA (1) MA26842A1 (xx)
MX (1) MXPA02003229A (xx)
MY (1) MY127678A (xx)
NO (2) NO20021780L (xx)
NZ (1) NZ517961A (xx)
OA (1) OA12070A (xx)
PA (1) PA8505201A1 (xx)
PE (1) PE20010740A1 (xx)
PL (1) PL354607A1 (xx)
PT (1) PT1226110E (xx)
SI (1) SI1226110T1 (xx)
SK (1) SK5232002A3 (xx)
SV (1) SV2001000188A (xx)
TR (2) TR200201094T2 (xx)
TW (2) TW200505824A (xx)
UA (1) UA72931C2 (xx)
WO (1) WO2001028978A1 (xx)
YU (2) YU73004A (xx)
ZA (1) ZA200202543B (xx)

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AR061728A1 (es) * 2006-06-30 2008-09-17 Pfizer Prod Inc Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
CN101600458A (zh) 2006-12-22 2009-12-09 瑞蔻达蒂爱尔兰有限公司 采用α2δ配体和NSAID的下泌尿道疾病的联合治疗
ES2433890T3 (es) 2007-09-28 2013-12-12 Daiichi Sankyo Company, Limited Derivado de aminoácido bicíclico
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WO2012169475A1 (ja) 2011-06-08 2012-12-13 第一三共株式会社 クライゼン転位反応による二環性化合物の製造方法
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CN104245951B (zh) 2012-04-10 2018-08-24 第一三共株式会社 使用酶对二环化合物光学拆分的方法
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IL149143A0 (en) 2002-11-10
AR045456A2 (es) 2005-10-26
DZ3197A1 (fr) 2001-04-26
HRP20020428B1 (en) 2006-02-28
SV2001000188A (es) 2001-09-07
GT200000183AA (es) 2005-06-17
HUP0203325A3 (en) 2003-12-29
CN1165518C (zh) 2004-09-08
DE60034157D1 (de) 2007-05-10
NO20043663L (no) 2002-04-16
ZA200202543B (en) 2003-09-23
MXPA02003229A (es) 2002-09-30
CA2386297A1 (en) 2001-04-26
EP1506955A1 (en) 2005-02-16
OA12070A (en) 2003-11-10
EP1226110B1 (en) 2005-04-20
EP1226110A1 (en) 2002-07-31
ECSP045393A (es) 2004-10-23
TW200505824A (en) 2005-02-16
AU1092001A (en) 2001-04-30
HRP20020428A2 (en) 2005-02-28
EE200200211A (et) 2003-06-16
UA72931C2 (uk) 2005-05-16
IS7497A (is) 2004-10-08
US20040152779A1 (en) 2004-08-05
JP3744928B2 (ja) 2006-02-15
DOP2000000083A (es) 2002-03-30
BR0014972B1 (pt) 2011-09-06
MY127678A (en) 2006-12-29
ATE358116T1 (de) 2007-04-15
JP3632191B2 (ja) 2005-03-23
PA8505201A1 (es) 2002-08-29
YU29302A (sh) 2005-06-10
KR100593349B1 (ko) 2006-06-26
IS6348A (is) 2002-04-17
EA200200293A1 (ru) 2002-10-31
AP2002002517A0 (en) 2002-06-30
SI1226110T1 (en) 2005-08-31
US6835751B2 (en) 2004-12-28
HUP0203325A2 (hu) 2003-02-28
AU2005201268A1 (en) 2005-04-21
TR200201094T2 (tr) 2002-09-23
AR026087A1 (es) 2002-12-26
HN2000000224A (es) 2001-04-11
CA2386297C (en) 2010-02-09
HK1049826A1 (en) 2003-05-30
DE60019628D1 (de) 2005-05-25
JP2003512348A (ja) 2003-04-02
DE60019628T2 (de) 2006-01-19
NO20021780D0 (no) 2002-04-16
PE20010740A1 (es) 2001-07-27
PL354607A1 (en) 2004-01-26
NO20021780L (no) 2002-04-16
KR100566462B1 (ko) 2006-03-31
US6689906B1 (en) 2004-02-10
BG106719A (bg) 2003-02-28
IL164060A0 (en) 2005-12-18
DE60034157T2 (de) 2007-12-13
CO5280060A1 (es) 2003-05-30
EP1506955B1 (en) 2007-03-28
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MA26842A1 (fr) 2004-12-20
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