IN2014DN07923A - - Google Patents
Info
- Publication number
- IN2014DN07923A IN2014DN07923A IN7923DEN2014A IN2014DN07923A IN 2014DN07923 A IN2014DN07923 A IN 2014DN07923A IN 7923DEN2014 A IN7923DEN2014 A IN 7923DEN2014A IN 2014DN07923 A IN2014DN07923 A IN 2014DN07923A
- Authority
- IN
- India
- Prior art keywords
- present
- optically active
- bicyclic compound
- active bicyclic
- enzyme
- Prior art date
Links
- -1 bicyclic compound Chemical class 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/12—Formation of amino and carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/32—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/85—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to a chemical modification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/20—All rings being cycloaliphatic the ring system containing seven carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012089481 | 2012-04-10 | ||
| PCT/JP2013/060597 WO2013154066A1 (ja) | 2012-04-10 | 2013-04-08 | 酵素を用いる二環性化合物の光学分割方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN07923A true IN2014DN07923A (enExample) | 2015-05-01 |
Family
ID=49327629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN7923DEN2014 IN2014DN07923A (enExample) | 2012-04-10 | 2013-04-08 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9394235B2 (enExample) |
| EP (1) | EP2837689B1 (enExample) |
| JP (1) | JP6023794B2 (enExample) |
| KR (1) | KR101976891B1 (enExample) |
| CN (1) | CN104245951B (enExample) |
| BR (1) | BR112014025158B1 (enExample) |
| CA (1) | CA2869994C (enExample) |
| ES (1) | ES2624314T3 (enExample) |
| HU (1) | HUE033397T2 (enExample) |
| IL (1) | IL235002B (enExample) |
| IN (1) | IN2014DN07923A (enExample) |
| TW (1) | TWI639702B (enExample) |
| WO (1) | WO2013154066A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI635071B (zh) * | 2013-07-08 | 2018-09-11 | 第一三共股份有限公司 | 光學活性二環γ－胺基酸衍生物及其製造方法 |
| US10150723B2 (en) | 2015-05-27 | 2018-12-11 | Novassay S.A. | Separation of enantiomers of 3-ethylbicyclo[3.2.0]hept-3-en-6-one |
| CN116903468B (zh) * | 2023-07-14 | 2024-01-26 | 山东新时代药业有限公司 | 一种米洛巴林中间体的制备方法 |
| WO2025118134A1 (zh) * | 2023-12-05 | 2025-06-12 | 浙江天宇药业股份有限公司 | 一种苯磺酸米洛巴林的合成方法 |
| CN122278784A (zh) * | 2024-12-26 | 2026-06-26 | 南京威凯尔生物医药科技有限公司 | 一种酮还原酶突变体及其用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60169434A (ja) * | 1984-02-14 | 1985-09-02 | Ube Ind Ltd | 光学活性なビシクロケトン類の製法 |
| ATE323067T1 (de) | 1997-10-27 | 2006-04-15 | Warner Lambert Co | Zyklische aminosäuren und deren derivate als arzneimittel |
| HN2000000224A (es) | 1999-10-20 | 2001-04-11 | Warner Lambert Co | Aminoacidos biciclicos como agentes farmaceuticos |
| CA2444053C (en) | 2001-04-19 | 2008-06-17 | Warner-Lambert Company Llc | Fused bicyclic or tricyclic amino acids |
| JP2005536507A (ja) | 2002-07-11 | 2005-12-02 | メルク エンド カムパニー インコーポレーテッド | ６Ｈ−ピロロ［３，４−ｄ］ピリダジン化合物による神経障害性疼痛の治療 |
| KR101335784B1 (ko) * | 2007-09-28 | 2013-12-05 | 다이이찌 산쿄 가부시키가이샤 | 2 고리성 γ-아미노산 유도체 |
| WO2010084798A1 (ja) * | 2009-01-21 | 2010-07-29 | 第一三共株式会社 | ３環性化合物 |
| WO2010110361A1 (ja) | 2009-03-26 | 2010-09-30 | 第一三共株式会社 | 二環性γ－アミノ酸誘導体の製造方法 |
| BR112013031360B1 (pt) | 2011-06-08 | 2022-01-25 | Daiichi Sankyo Company, Limited | Método para produzir um composto |
| ES2649968T3 (es) * | 2011-06-08 | 2018-01-16 | Daiichi Sankyo Company, Limited | Procedimiento de producción de un compuesto bicíclico vía transposición de Claisen |
-
2013
- 2013-04-08 HU HUE13775061A patent/HUE033397T2/en unknown
- 2013-04-08 CN CN201380019311.6A patent/CN104245951B/zh active Active
- 2013-04-08 BR BR112014025158-4A patent/BR112014025158B1/pt active IP Right Grant
- 2013-04-08 ES ES13775061.8T patent/ES2624314T3/es active Active
- 2013-04-08 IN IN7923DEN2014 patent/IN2014DN07923A/en unknown
- 2013-04-08 WO PCT/JP2013/060597 patent/WO2013154066A1/ja not_active Ceased
- 2013-04-08 EP EP13775061.8A patent/EP2837689B1/en active Active
- 2013-04-08 KR KR1020147028140A patent/KR101976891B1/ko active Active
- 2013-04-08 JP JP2014510158A patent/JP6023794B2/ja active Active
- 2013-04-08 CA CA2869994A patent/CA2869994C/en active Active
- 2013-04-09 TW TW102112438A patent/TWI639702B/zh active
-
2014
- 2014-10-06 IL IL235002A patent/IL235002B/en active IP Right Grant
- 2014-10-10 US US14/511,386 patent/US9394235B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150038738A1 (en) | 2015-02-05 |
| US9394235B2 (en) | 2016-07-19 |
| TW201346036A (zh) | 2013-11-16 |
| BR112014025158A2 (pt) | 2017-07-18 |
| KR20150004804A (ko) | 2015-01-13 |
| JP6023794B2 (ja) | 2016-11-09 |
| ES2624314T3 (es) | 2017-07-13 |
| EP2837689B1 (en) | 2017-02-15 |
| BR112014025158B1 (pt) | 2021-09-21 |
| KR101976891B1 (ko) | 2019-05-09 |
| CN104245951B (zh) | 2018-08-24 |
| TWI639702B (zh) | 2018-11-01 |
| CA2869994C (en) | 2017-05-30 |
| HK1205192A1 (en) | 2015-12-11 |
| HUE033397T2 (en) | 2017-12-28 |
| EP2837689A1 (en) | 2015-02-18 |
| JPWO2013154066A1 (ja) | 2015-12-17 |
| WO2013154066A1 (ja) | 2013-10-17 |
| IL235002B (en) | 2018-04-30 |
| CN104245951A (zh) | 2014-12-24 |
| CA2869994A1 (en) | 2013-10-17 |
| EP2837689A4 (en) | 2015-09-09 |
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