SK4952000A3 - 3-amino-3-arylpropan-1-ol derivatives, process for their preparation, medicaments containing the same and their use - Google Patents

3-amino-3-arylpropan-1-ol derivatives, process for their preparation, medicaments containing the same and their use Download PDF

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Publication number
SK4952000A3
SK4952000A3 SK495-2000A SK4952000A SK4952000A3 SK 4952000 A3 SK4952000 A3 SK 4952000A3 SK 4952000 A SK4952000 A SK 4952000A SK 4952000 A3 SK4952000 A3 SK 4952000A3
Authority
SK
Slovakia
Prior art keywords
formula
group
substituted
compounds
amino
Prior art date
Application number
SK495-2000A
Other languages
English (en)
Slovak (sk)
Inventor
Bernd Sundermann
Hagen-Heinrich Hennies
Babette-Yvonne Kogel
Helmut Buschmann
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of SK4952000A3 publication Critical patent/SK4952000A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
SK495-2000A 1999-04-07 2000-04-06 3-amino-3-arylpropan-1-ol derivatives, process for their preparation, medicaments containing the same and their use SK4952000A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19915602A DE19915602A1 (de) 1999-04-07 1999-04-07 3-Amino-4-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
SK4952000A3 true SK4952000A3 (en) 2000-10-09

Family

ID=7903731

Family Applications (1)

Application Number Title Priority Date Filing Date
SK495-2000A SK4952000A3 (en) 1999-04-07 2000-04-06 3-amino-3-arylpropan-1-ol derivatives, process for their preparation, medicaments containing the same and their use

Country Status (26)

Country Link
US (2) US6288278B1 (pt)
EP (1) EP1043306B1 (pt)
JP (1) JP2000327643A (pt)
KR (1) KR100686475B1 (pt)
CN (1) CN1147461C (pt)
AR (1) AR023374A1 (pt)
AT (1) ATE263138T1 (pt)
AU (1) AU777873B2 (pt)
BR (1) BR0008681A (pt)
CA (1) CA2303721A1 (pt)
CO (1) CO5170510A1 (pt)
DE (2) DE19915602A1 (pt)
DK (1) DK1043306T3 (pt)
ES (1) ES2218016T3 (pt)
HK (1) HK1031722A1 (pt)
HU (1) HUP0001397A2 (pt)
IL (1) IL135452A (pt)
NO (1) NO325029B1 (pt)
NZ (1) NZ503397A (pt)
PE (1) PE20001647A1 (pt)
PL (1) PL339487A1 (pt)
PT (1) PT1043306E (pt)
SI (1) SI1043306T1 (pt)
SK (1) SK4952000A3 (pt)
UA (1) UA70307C2 (pt)
ZA (1) ZA200001747B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19915601A1 (de) 1999-04-07 2000-10-19 Gruenenthal Gmbh 3-Amino-3-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung
DE10108307A1 (de) 2001-02-21 2002-08-29 Gruenenthal Gmbh Substituierte Propan-1,3-diamin-Derivate
SI1458386T1 (sl) * 2001-12-27 2007-08-31 Ortho Mcneil Pharm Inc Aroil pirol heteroeril in metanoli, uporabni za zdravljenje motnje centralnega živčnega sistema
DE10213051B4 (de) * 2002-03-23 2013-03-07 Grünenthal GmbH Substituierte 4-Aminocyclohexanole
DE102005033732B4 (de) * 2005-05-27 2014-02-13 Grünenthal GmbH Trennung stereoisomerer N,N-Dialkylamino-2-alkyl-3-hydroxy-3-phenyl-alkane

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017637A (en) * 1973-03-26 1977-04-12 American Home Products Corporation Benzylamine analgesics
US3937818A (en) * 1974-03-27 1976-02-10 American Home Products Corporation Benzylamine narcotic antagonists
US3975436A (en) * 1974-03-27 1976-08-17 American Home Products Corporation Benzylamine narcotic antagonists
US4143158A (en) * 1978-03-24 1979-03-06 American Home Products Corporation Inhibition of prolactin release by an opiate antagonist
RO112851B1 (ro) * 1992-10-26 1998-01-30 Goedecke Ag Derivat de tilidina, procedeu de preparare a acestuia si compozitie farmaceutica continand acest derivat
DE19915601A1 (de) * 1999-04-07 2000-10-19 Gruenenthal Gmbh 3-Amino-3-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung

Also Published As

Publication number Publication date
AU777873B2 (en) 2004-11-04
AU2645000A (en) 2000-10-12
PL339487A1 (en) 2000-10-09
USRE39530E1 (en) 2007-03-27
IL135452A0 (en) 2001-05-20
ZA200001747B (en) 2000-10-26
HK1031722A1 (en) 2001-06-22
ATE263138T1 (de) 2004-04-15
NZ503397A (en) 2001-04-27
CN1147461C (zh) 2004-04-28
DE50005841D1 (de) 2004-05-06
EP1043306A2 (de) 2000-10-11
EP1043306B1 (de) 2004-03-31
CN1270163A (zh) 2000-10-18
NO20001782D0 (no) 2000-04-06
HU0001397D0 (en) 2000-06-28
ES2218016T3 (es) 2004-11-16
HUP0001397A2 (hu) 2002-04-29
KR100686475B1 (ko) 2007-02-23
PE20001647A1 (es) 2001-01-20
NO325029B1 (no) 2008-01-21
CA2303721A1 (en) 2000-10-07
US6288278B1 (en) 2001-09-11
KR20000071570A (ko) 2000-11-25
EP1043306A3 (de) 2001-07-18
AR023374A1 (es) 2002-09-04
DK1043306T3 (da) 2004-07-05
JP2000327643A (ja) 2000-11-28
DE19915602A1 (de) 2000-10-19
NO20001782L (no) 2000-10-09
UA70307C2 (en) 2004-10-15
BR0008681A (pt) 2002-02-26
PT1043306E (pt) 2004-08-31
CO5170510A1 (es) 2002-06-27
SI1043306T1 (en) 2004-10-31
IL135452A (en) 2004-02-08

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