SK4092001A3 - (+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride - Google Patents
(+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride Download PDFInfo
- Publication number
- SK4092001A3 SK4092001A3 SK409-2001A SK4092001A SK4092001A3 SK 4092001 A3 SK4092001 A3 SK 4092001A3 SK 4092001 A SK4092001 A SK 4092001A SK 4092001 A3 SK4092001 A3 SK 4092001A3
- Authority
- SK
- Slovakia
- Prior art keywords
- difluoromethylornitine
- difluoromethyl
- alpha
- ornithine
- tartaric acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98117982 | 1998-09-23 | ||
PCT/EP1999/007060 WO2000017153A1 (de) | 1998-09-23 | 1999-09-22 | VERFAHREN ZUR HERSTELLUNG VON (-)-α-(DIFLUORMETHYL)ORNITHIN-MONOHYDROCHLORID MONOHYDRAT |
Publications (1)
Publication Number | Publication Date |
---|---|
SK4092001A3 true SK4092001A3 (en) | 2002-06-04 |
Family
ID=8232678
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK409-2001A SK4092001A3 (en) | 1998-09-23 | 1999-09-22 | (+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride |
Country Status (16)
Country | Link |
---|---|
US (1) | US6462229B1 (hu) |
EP (1) | EP1115696A1 (hu) |
JP (1) | JP2002526468A (hu) |
KR (1) | KR20010079913A (hu) |
CN (1) | CN1319085A (hu) |
AU (1) | AU764154B2 (hu) |
BR (1) | BR9914034A (hu) |
CA (1) | CA2345112A1 (hu) |
CZ (1) | CZ20011043A3 (hu) |
HU (1) | HUP0103658A3 (hu) |
IL (1) | IL142218A0 (hu) |
MX (1) | MXPA01003032A (hu) |
NO (1) | NO20011480L (hu) |
PL (1) | PL195164B1 (hu) |
SK (1) | SK4092001A3 (hu) |
WO (1) | WO2000017153A1 (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1315777C (zh) * | 2003-01-16 | 2007-05-16 | 东丽泛应化学(股) | 旋光二酰基酒石酸的回收方法 |
WO2005021502A1 (ja) * | 2003-08-29 | 2005-03-10 | Takeda Pharmaceutical Company Limited | 光学活性トレオ−β−アルキルトリプトファン誘導体の製造法およびその中間体 |
TW201617326A (zh) * | 2014-03-06 | 2016-05-16 | Alphora研發股份有限公司 | (s)-1-((2r,3r,4s,5s)-5-烯丙-3-甲氧-4-(對甲苯磺醯甲基)四氫呋喃-2-基)-3-氨基丙-2-醇之結晶衍生物 |
EP3256117A4 (en) * | 2015-02-12 | 2018-10-10 | The Arizona Board of Regents on behalf of The University of Arizona | Methods for treating neuroblastoma |
CN105660637B (zh) * | 2016-01-07 | 2018-04-24 | 南京中医药大学 | 防治当归早薹的药物及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4309442A (en) * | 1977-07-11 | 1982-01-05 | Merrell Toraude Et Compagnie | Method for controlling fertility in mammals |
US4414141A (en) | 1980-11-21 | 1983-11-08 | The Lummus Company | Hydrotreating catalyst |
US4931557A (en) | 1988-10-17 | 1990-06-05 | Eli Lilly And Company | Method of resolving cis 3-amino-4-(2-furyl)vinyl)-1-methoxycarbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof |
AU4751597A (en) * | 1996-10-04 | 1998-04-24 | Ilex Oncology, Inc. | Dfmo and taxol for the treatment or prevention of breast cancer |
AU5526898A (en) | 1996-12-13 | 1998-07-03 | Ilex Oncology, Inc. | Isomeric pharmaceutical formulation containing dfmo for the treatment of cancer |
-
1999
- 1999-09-22 US US09/787,420 patent/US6462229B1/en not_active Expired - Fee Related
- 1999-09-22 HU HU0103658A patent/HUP0103658A3/hu unknown
- 1999-09-22 WO PCT/EP1999/007060 patent/WO2000017153A1/de not_active Application Discontinuation
- 1999-09-22 CN CN99811257A patent/CN1319085A/zh active Pending
- 1999-09-22 IL IL14221899A patent/IL142218A0/xx unknown
- 1999-09-22 SK SK409-2001A patent/SK4092001A3/sk unknown
- 1999-09-22 CZ CZ20011043A patent/CZ20011043A3/cs unknown
- 1999-09-22 AU AU60865/99A patent/AU764154B2/en not_active Ceased
- 1999-09-22 MX MXPA01003032A patent/MXPA01003032A/es not_active Application Discontinuation
- 1999-09-22 KR KR1020017003766A patent/KR20010079913A/ko not_active Application Discontinuation
- 1999-09-22 EP EP99947408A patent/EP1115696A1/de not_active Withdrawn
- 1999-09-22 BR BR9914034-9A patent/BR9914034A/pt not_active IP Right Cessation
- 1999-09-22 PL PL99346900A patent/PL195164B1/pl not_active IP Right Cessation
- 1999-09-22 JP JP2000574063A patent/JP2002526468A/ja active Pending
- 1999-09-22 CA CA002345112A patent/CA2345112A1/en not_active Abandoned
-
2001
- 2001-03-22 NO NO20011480A patent/NO20011480L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20011480D0 (no) | 2001-03-22 |
HUP0103658A3 (en) | 2003-03-28 |
BR9914034A (pt) | 2001-08-14 |
CN1319085A (zh) | 2001-10-24 |
AU6086599A (en) | 2000-04-10 |
CZ20011043A3 (cs) | 2001-09-12 |
US6462229B1 (en) | 2002-10-08 |
IL142218A0 (en) | 2002-03-10 |
KR20010079913A (ko) | 2001-08-22 |
JP2002526468A (ja) | 2002-08-20 |
HU0103658D0 (en) | 2002-02-28 |
HUP0103658A2 (hu) | 2002-12-28 |
EP1115696A1 (de) | 2001-07-18 |
CA2345112A1 (en) | 2000-03-30 |
WO2000017153A1 (de) | 2000-03-30 |
MXPA01003032A (es) | 2002-07-02 |
NO20011480L (no) | 2001-03-23 |
AU764154B2 (en) | 2003-08-14 |
PL346900A1 (en) | 2002-03-11 |
PL195164B1 (pl) | 2007-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SHIBANUMA et al. | Synthesis of optically active 2-(N-benzyl-N-methylamino) ethyl methyl 2, 6-dimethyl-4-(m-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate (Nicardipine) | |
HU211695A9 (en) | Substituted pyridyl-dihydroxy-heptenoic acid and its salts | |
ES2375920T3 (es) | Procedimiento para resolver derivados de isoquinole�?na. | |
DE4137773A1 (de) | Herstellung und verwendung von salzen der reinen enantiomere der (alpha)-liponsaeure | |
FI110096B (fi) | Menetelmä terapeuttisesti käyttökelpoisen kiteisen Tiagabine-hydrokloridimonohydraatin valmistamiseksi | |
US11897843B2 (en) | Process for the preparation of enantiomerically enriched 3-aminopiperidine | |
WO1996036636A1 (en) | Process for preparing 4-aryl-piperidine derivatives | |
IE69017B1 (en) | Improved process for resolution of racemic cimaterol (-)-cimaterol and derivatives thereof | |
SK4092001A3 (en) | (+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride | |
CZ294964B6 (cs) | Způsob přípravy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)fenyl]hydrazon]propandinitrilu s optickou čistotou nad 90 % | |
JP2002529462A (ja) | ラセミ化方法 | |
HRP20010920A2 (en) | Polymorphs of crystalline (2-benzhydryl-1-azabicyclo[2,2,2]oct-3-yl)-(5-isopropyl-2-methoxybenzyl)-ammoniumchloride as nk-1 receptor antagonists | |
JP2004511476A (ja) | R(+)α−リポ酸の製造方法 | |
EP0174358A1 (en) | Novel diastereomer salts of phenylalanine and n-acyl derivatives thereof and process for the separation of optically active phenylalanine and n-acyl derivatives thereof | |
US3055888A (en) | 2-alkylmercapto-9-[2'-(n-alkylpiperidyl-2" and pyrrolidyl-2")-ethylidene-1']-thiaxanthenes | |
Pankaskie et al. | An Improved Synthetic Route to Aminoxypropylamine (Apa) and Related Homologs | |
JPH04230379A (ja) | 5−イソチアゾールアミン誘導体 | |
SK17342001A3 (sk) | Polymorfné formy kryštalického (2-benzhydryl-1-azabicyklo- [2.2.2]okt-3-yl)-(5-izopropyl-2-metoxybenzyl)amín-citrátu ako antagonistov receptora NK-1 | |
US4024082A (en) | Analgesics | |
JPS61501704A (ja) | 光学的活性フェニルアラニンおよびそれらのn−アシル誘導体並びにそれらの化合物の新規なジアステレオマ−塩の製造方法 | |
EP1934229A2 (en) | Processes for the preparation of different forms of (s)-(+)-clopidogrel besylate | |
HU179780B (en) | Process for preparing thiazolidine-carboxylic acid derivatives | |
PL184026B1 (pl) | Sposób otrzymywania spiropiperydylowych pochodnych ryfamycyny S oraz zawierające je kompozycje farmaceutyczne | |
AT367029B (de) | Verfahren zur herstellung von neuen racemischen oder optisch aktiven phenylessigsaeureamiden | |
HRP20000490A2 (en) | Process for the preparation of amlodipine besilate |