SK4092001A3 - (+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride - Google Patents

(+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride Download PDF

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Publication number
SK4092001A3
SK4092001A3 SK409-2001A SK4092001A SK4092001A3 SK 4092001 A3 SK4092001 A3 SK 4092001A3 SK 4092001 A SK4092001 A SK 4092001A SK 4092001 A3 SK4092001 A3 SK 4092001A3
Authority
SK
Slovakia
Prior art keywords
difluoromethylornitine
difluoromethyl
alpha
ornithine
tartaric acid
Prior art date
Application number
SK409-2001A
Other languages
English (en)
Slovak (sk)
Inventor
Thomas Meul
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of SK4092001A3 publication Critical patent/SK4092001A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30Preparation of optical isomers
    • C07C227/34Preparation of optical isomers by separation of optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SK409-2001A 1998-09-23 1999-09-22 (+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride SK4092001A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98117982 1998-09-23
PCT/EP1999/007060 WO2000017153A1 (de) 1998-09-23 1999-09-22 VERFAHREN ZUR HERSTELLUNG VON (-)-α-(DIFLUORMETHYL)ORNITHIN-MONOHYDROCHLORID MONOHYDRAT

Publications (1)

Publication Number Publication Date
SK4092001A3 true SK4092001A3 (en) 2002-06-04

Family

ID=8232678

Family Applications (1)

Application Number Title Priority Date Filing Date
SK409-2001A SK4092001A3 (en) 1998-09-23 1999-09-22 (+)- or (-)-alpha-(difluoromethyl)ornithine diastereoisomeric salts and method for producing (-)-alpha-(difluoromethyl) ornithine monohydrochloride

Country Status (16)

Country Link
US (1) US6462229B1 (hu)
EP (1) EP1115696A1 (hu)
JP (1) JP2002526468A (hu)
KR (1) KR20010079913A (hu)
CN (1) CN1319085A (hu)
AU (1) AU764154B2 (hu)
BR (1) BR9914034A (hu)
CA (1) CA2345112A1 (hu)
CZ (1) CZ20011043A3 (hu)
HU (1) HUP0103658A3 (hu)
IL (1) IL142218A0 (hu)
MX (1) MXPA01003032A (hu)
NO (1) NO20011480L (hu)
PL (1) PL195164B1 (hu)
SK (1) SK4092001A3 (hu)
WO (1) WO2000017153A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1315777C (zh) * 2003-01-16 2007-05-16 东丽泛应化学(股) 旋光二酰基酒石酸的回收方法
WO2005021502A1 (ja) * 2003-08-29 2005-03-10 Takeda Pharmaceutical Company Limited 光学活性トレオ−β−アルキルトリプトファン誘導体の製造法およびその中間体
TW201617326A (zh) * 2014-03-06 2016-05-16 Alphora研發股份有限公司 (s)-1-((2r,3r,4s,5s)-5-烯丙-3-甲氧-4-(對甲苯磺醯甲基)四氫呋喃-2-基)-3-氨基丙-2-醇之結晶衍生物
EP3256117A4 (en) * 2015-02-12 2018-10-10 The Arizona Board of Regents on behalf of The University of Arizona Methods for treating neuroblastoma
CN105660637B (zh) * 2016-01-07 2018-04-24 南京中医药大学 防治当归早薹的药物及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309442A (en) * 1977-07-11 1982-01-05 Merrell Toraude Et Compagnie Method for controlling fertility in mammals
US4414141A (en) 1980-11-21 1983-11-08 The Lummus Company Hydrotreating catalyst
US4931557A (en) 1988-10-17 1990-06-05 Eli Lilly And Company Method of resolving cis 3-amino-4-(2-furyl)vinyl)-1-methoxycarbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof
AU4751597A (en) * 1996-10-04 1998-04-24 Ilex Oncology, Inc. Dfmo and taxol for the treatment or prevention of breast cancer
AU5526898A (en) 1996-12-13 1998-07-03 Ilex Oncology, Inc. Isomeric pharmaceutical formulation containing dfmo for the treatment of cancer

Also Published As

Publication number Publication date
NO20011480D0 (no) 2001-03-22
HUP0103658A3 (en) 2003-03-28
BR9914034A (pt) 2001-08-14
CN1319085A (zh) 2001-10-24
AU6086599A (en) 2000-04-10
CZ20011043A3 (cs) 2001-09-12
US6462229B1 (en) 2002-10-08
IL142218A0 (en) 2002-03-10
KR20010079913A (ko) 2001-08-22
JP2002526468A (ja) 2002-08-20
HU0103658D0 (en) 2002-02-28
HUP0103658A2 (hu) 2002-12-28
EP1115696A1 (de) 2001-07-18
CA2345112A1 (en) 2000-03-30
WO2000017153A1 (de) 2000-03-30
MXPA01003032A (es) 2002-07-02
NO20011480L (no) 2001-03-23
AU764154B2 (en) 2003-08-14
PL346900A1 (en) 2002-03-11
PL195164B1 (pl) 2007-08-31

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