SK35198A3 - Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof - Google Patents
Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof Download PDFInfo
- Publication number
- SK35198A3 SK35198A3 SK351-98A SK35198A SK35198A3 SK 35198 A3 SK35198 A3 SK 35198A3 SK 35198 A SK35198 A SK 35198A SK 35198 A3 SK35198 A3 SK 35198A3
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- substituted
- optionally substituted
- alkylamino
- alkoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24171695 | 1995-09-20 | ||
| PCT/JP1996/002696 WO1997011055A1 (fr) | 1995-09-20 | 1996-09-19 | Derives d'acryloylguanidine a substitution heteroaryle et leurs composition medicinale |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK35198A3 true SK35198A3 (en) | 1999-06-11 |
Family
ID=17078479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK351-98A SK35198A3 (en) | 1995-09-20 | 1996-09-19 | Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0861831A4 (hu) |
| KR (1) | KR19990063589A (hu) |
| CN (1) | CN1196721A (hu) |
| AU (1) | AU702092B2 (hu) |
| BR (1) | BR9610530A (hu) |
| CA (1) | CA2232497A1 (hu) |
| CZ (1) | CZ84098A3 (hu) |
| HU (1) | HUP9901336A3 (hu) |
| NO (1) | NO981241L (hu) |
| PL (1) | PL326033A1 (hu) |
| SK (1) | SK35198A3 (hu) |
| WO (1) | WO1997011055A1 (hu) |
| ZA (1) | ZA967800B (hu) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002515854A (ja) * | 1995-08-02 | 2002-05-28 | スミスクライン・ビーチャム・コーポレイション | エンドセリン受容体拮抗薬 |
| EP0972767A4 (en) * | 1997-03-06 | 2000-05-24 | Toa Eiyo Ltd | CYCLOALCA [b] PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, THEIR PRODUCTION PROCESS AND MEDICAMENTS CONTAINING THEM |
| EP1206464A4 (en) * | 1999-08-23 | 2002-12-18 | Smithkline Beecham Corp | FATTY ACID SYNTHASE INHIBITORS |
| WO2002051441A1 (fr) * | 2000-12-26 | 2002-07-04 | Sankyo Company, Limited | Compositions medicinales contenant un diuretique et un agent renforçant la resistance a l'insuline |
| AU2005264917A1 (en) | 2004-06-16 | 2006-01-26 | Wyeth | Diphenylimidazopyrimidine and -imidazole amines as inhibitors of B-secretase |
| PE20060459A1 (es) | 2004-06-16 | 2006-05-30 | Wyeth Corp | DERIVADOS DE AMINO-5,5-DIFENILIMIDAZOLONA COMO INHIBIDORES DE LA ß-SECRETASA |
| CN101103034A (zh) | 2005-01-14 | 2008-01-09 | 惠氏公司 | 抑制β-分泌酶的氨基-咪唑酮 |
| WO2006083760A1 (en) | 2005-02-01 | 2006-08-10 | Wyeth | AMINO-PYRIDINES AS INHIBITORS OF β-SECRETASE |
| CN101146769A (zh) | 2005-02-14 | 2008-03-19 | 惠氏公司 | 作为β-分泌酶抑制剂的唑基酰基胍 |
| WO2006088694A1 (en) | 2005-02-14 | 2006-08-24 | Wyeth | SUBSTITUTED THIENYL AND FURYL ACYLGUANIDINES AS β-SECRETASE MODULATORS |
| WO2007005404A1 (en) | 2005-06-30 | 2007-01-11 | Wyeth | AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION |
| TW200738683A (en) | 2005-06-30 | 2007-10-16 | Wyeth Corp | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation |
| EP2256107A1 (en) | 2005-09-26 | 2010-12-01 | Wyeth LLC | Amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compounds as inhibitors of the beta-secretase (BACE) |
| WO2007100536A1 (en) | 2006-02-24 | 2007-09-07 | Wyeth | DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE |
| US7700606B2 (en) | 2006-08-17 | 2010-04-20 | Wyeth Llc | Imidazole amines as inhibitors of β-secretase |
| PE20090617A1 (es) | 2007-03-23 | 2009-05-08 | Wyeth Corp | Compuestos amino-5-[-4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de -secretasa |
| WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| ATE139526T1 (de) * | 1992-02-15 | 1996-07-15 | Hoechst Ag | 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen |
| JP3162572B2 (ja) * | 1993-04-28 | 2001-05-08 | 住友製薬株式会社 | インドロイルグアニジン誘導体 |
| US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
| DE4430861A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
| JPH0959245A (ja) * | 1995-08-25 | 1997-03-04 | Yamanouchi Pharmaceut Co Ltd | Ｎ−（２−プロペノイル）グアニジン誘導体 |
-
1996
- 1996-09-16 ZA ZA967800A patent/ZA967800B/xx unknown
- 1996-09-19 AU AU70007/96A patent/AU702092B2/en not_active Ceased
- 1996-09-19 CA CA002232497A patent/CA2232497A1/en not_active Abandoned
- 1996-09-19 CN CN96196999A patent/CN1196721A/zh active Pending
- 1996-09-19 WO PCT/JP1996/002696 patent/WO1997011055A1/ja not_active Application Discontinuation
- 1996-09-19 PL PL96326033A patent/PL326033A1/xx unknown
- 1996-09-19 HU HU9901336A patent/HUP9901336A3/hu unknown
- 1996-09-19 BR BR9610530A patent/BR9610530A/pt not_active Application Discontinuation
- 1996-09-19 EP EP96931252A patent/EP0861831A4/en not_active Withdrawn
- 1996-09-19 CZ CZ98840A patent/CZ84098A3/cs unknown
- 1996-09-19 SK SK351-98A patent/SK35198A3/sk unknown
- 1996-09-19 KR KR1019980702028A patent/KR19990063589A/ko not_active Application Discontinuation
-
1998
- 1998-03-19 NO NO981241A patent/NO981241L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO981241L (no) | 1998-05-20 |
| NO981241D0 (no) | 1998-03-19 |
| WO1997011055A1 (fr) | 1997-03-27 |
| AU7000796A (en) | 1997-04-09 |
| KR19990063589A (ko) | 1999-07-26 |
| BR9610530A (pt) | 1999-07-06 |
| EP0861831A4 (en) | 1998-11-11 |
| CA2232497A1 (en) | 1997-03-27 |
| AU702092B2 (en) | 1999-02-11 |
| EP0861831A1 (en) | 1998-09-02 |
| HUP9901336A2 (hu) | 1999-08-30 |
| MX9802238A (es) | 1998-08-30 |
| HUP9901336A3 (en) | 2000-02-28 |
| CN1196721A (zh) | 1998-10-21 |
| PL326033A1 (en) | 1998-08-17 |
| CZ84098A3 (cs) | 1998-09-16 |
| ZA967800B (en) | 1997-04-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SK35198A3 (en) | Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof | |
| KR101589332B1 (ko) | ２ｈ-크로멘 화합물 및 그의 유도체 | |
| US6730792B2 (en) | β3 adrenergic agonists | |
| EP1448560B1 (en) | 3-SUBSTITUTED OXINDOLE beta 3 AGONISTS | |
| JP5140854B2 (ja) | Ｓ１ｐ３受容体拮抗剤 | |
| JP5309033B2 (ja) | ヘテロアリールシクロプロパンカルボキサミド及び薬剤としてのその使用 | |
| JP4815083B2 (ja) | 複素環化合物およびそれの使用方法 | |
| US20080318958A1 (en) | New utilities of tricyclic compounds | |
| WO1999019303A1 (fr) | Derives de pyrazole | |
| KR20080080305A (ko) | 트롬보포이에틴 활성 조절 화합물 및 이의 조절 방법 | |
| AU2006287513A1 (en) | 1, 3-disubstituted indole derivatives for use as PPAR modulators | |
| KR20070100894A (ko) | 혈전색전성 장애 치료용 ｐ2ｙ1 수용체 억제제로서의2-페녹시-ｎ-(1,3,4-티아디졸-2-일)피리딘-3-아민 유도체및 관련 화합물 | |
| JP2007525482A (ja) | イオンチャネルリガンドとしてのアミド化合物およびその使用 | |
| JPWO2009005076A1 (ja) | アミド化合物 | |
| PT1258484E (pt) | Novos compostos de isoxazol e de tiazol e sua utilização enquanto fármacos | |
| LV12633B (en) | REGULATORY AGENT FOR THE RETINOIC PREPARATOR'S FUNCTION | |
| JP5371775B2 (ja) | ヘテロアリール置換カルボキサミド及びｎｏシンターゼの発現を刺激するためのその使用 | |
| EP2099753A2 (en) | Heteroarylacrylamides and their use as pharmaceuticals | |
| KR20150125716A (ko) | 새로운 술폰아미드 trpa1 수용체 길항제 | |
| JP2011503042A (ja) | ｐ３８ＭＡＰキナーゼ阻害剤 | |
| JP2002506033A (ja) | ビトロネクチン受容体アンタゴニスト | |
| WO2008053863A1 (fr) | Nouveau composé ayant un squelette de 1,4-benzothiazin-3-one ou un squelette de 3,4-dihydroquinolin-2-one | |
| WO2003002540A1 (en) | Cyclic diamine compound having five-membered cyclic group | |
| KR100248643B1 (ko) | 아릴 및 헤테로아릴 알콕시나프탈렌 유도체 | |
| WO1998027061A1 (fr) | Derives de guanidine n-[(heteroaryle a cinq chainons substitue) carbonyle] |