SK287902B6 - Multiparticulate drug form and method for the preparation thereof - Google Patents

Multiparticulate drug form and method for the preparation thereof Download PDF

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Publication number
SK287902B6
SK287902B6 SK1374-2002A SK13742002A SK287902B6 SK 287902 B6 SK287902 B6 SK 287902B6 SK 13742002 A SK13742002 A SK 13742002A SK 287902 B6 SK287902 B6 SK 287902B6
Authority
SK
Slovakia
Prior art keywords
weight
meth
acrylate
dosage form
release
Prior art date
Application number
SK1374-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK13742002A3 (sk
Inventor
Thomas Beckert
Hans-Ulrich Petereit
Jennifer Dressman
Markus Rudolph
Original Assignee
Evonik Rohm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10104880A external-priority patent/DE10104880A1/de
Application filed by Evonik Rohm Gmbh filed Critical Evonik Rohm Gmbh
Publication of SK13742002A3 publication Critical patent/SK13742002A3/sk
Publication of SK287902B6 publication Critical patent/SK287902B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK1374-2002A 2001-01-31 2001-03-09 Multiparticulate drug form and method for the preparation thereof SK287902B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10104504 2001-01-31
DE10104880A DE10104880A1 (de) 2001-01-31 2001-02-01 Multipartikuläre Arzneiform, enthaltend mindestens zwei unterschiedlich überzogene Pelletformen
PCT/EP2001/002679 WO2002060415A1 (de) 2001-01-31 2001-03-09 Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen

Publications (2)

Publication Number Publication Date
SK13742002A3 SK13742002A3 (sk) 2004-05-04
SK287902B6 true SK287902B6 (sk) 2012-03-02

Family

ID=26008387

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1374-2002A SK287902B6 (sk) 2001-01-31 2001-03-09 Multiparticulate drug form and method for the preparation thereof

Country Status (14)

Country Link
US (2) US6897205B2 (ja)
EP (1) EP1248599B1 (ja)
JP (1) JP5502254B2 (ja)
KR (1) KR100507946B1 (ja)
AT (1) ATE380022T1 (ja)
CA (1) CA2403670C (ja)
DE (1) DE50113344D1 (ja)
ES (1) ES2298236T3 (ja)
HU (1) HU229291B1 (ja)
IL (1) IL151150A0 (ja)
MX (1) MXPA02009478A (ja)
PL (1) PL201766B1 (ja)
SK (1) SK287902B6 (ja)
WO (1) WO2002060415A1 (ja)

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CA2403670A1 (en) 2002-08-08
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KR100507946B1 (ko) 2005-08-17
US6897205B2 (en) 2005-05-24
KR20030009407A (ko) 2003-01-29
US20050053660A1 (en) 2005-03-10
MXPA02009478A (es) 2003-03-10
HUP0301887A3 (en) 2006-07-28
EP1248599B1 (de) 2007-12-05
US7438929B2 (en) 2008-10-21
PL201766B1 (pl) 2009-05-29
JP5502254B2 (ja) 2014-05-28
WO2002060415A1 (de) 2002-08-08
EP1248599A1 (de) 2002-10-16
US20030152627A1 (en) 2003-08-14
PL356962A1 (en) 2004-07-12
DE50113344D1 (de) 2008-01-17
HUP0301887A2 (hu) 2003-09-29
IL151150A0 (en) 2003-04-10
ES2298236T3 (es) 2008-05-16
JP2004517156A (ja) 2004-06-10
ATE380022T1 (de) 2007-12-15
HU229291B1 (en) 2013-10-28

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