SK287633B6 - Spôsob výroby humánneho gamaglobulínu G a humánny gamaglobulín G s inaktivovanými vírusmi - Google Patents

Spôsob výroby humánneho gamaglobulínu G a humánny gamaglobulín G s inaktivovanými vírusmi Download PDF

Info

Publication number
SK287633B6
SK287633B6 SK58-2002A SK582002A SK287633B6 SK 287633 B6 SK287633 B6 SK 287633B6 SK 582002 A SK582002 A SK 582002A SK 287633 B6 SK287633 B6 SK 287633B6
Authority
SK
Slovakia
Prior art keywords
solution
globulin
concentration
peg
human
Prior art date
Application number
SK58-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK582002A3 (en
Inventor
Debart Pere Ristol
Gim�Nez Francisco Rabaneda
Hern�Ndez Ma Teresa L�Pez
Original Assignee
Grifols, S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols, S. A. filed Critical Grifols, S. A.
Publication of SK582002A3 publication Critical patent/SK582002A3/sk
Publication of SK287633B6 publication Critical patent/SK287633B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
SK58-2002A 2001-01-17 2002-01-11 Spôsob výroby humánneho gamaglobulínu G a humánny gamaglobulín G s inaktivovanými vírusmi SK287633B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200100101A ES2184594B1 (es) 2001-01-17 2001-01-17 Procedimiento para la produccion de gammaglobulina g humana inactivada de virus.

Publications (2)

Publication Number Publication Date
SK582002A3 SK582002A3 (en) 2002-10-08
SK287633B6 true SK287633B6 (sk) 2011-04-05

Family

ID=8496419

Family Applications (1)

Application Number Title Priority Date Filing Date
SK58-2002A SK287633B6 (sk) 2001-01-17 2002-01-11 Spôsob výroby humánneho gamaglobulínu G a humánny gamaglobulín G s inaktivovanými vírusmi

Country Status (14)

Country Link
US (1) US6875848B2 (hu)
EP (1) EP1225180B1 (hu)
JP (1) JP4070468B2 (hu)
AR (1) AR032242A1 (hu)
AT (1) ATE382631T1 (hu)
CZ (1) CZ300413B6 (hu)
DE (1) DE60224310T2 (hu)
ES (2) ES2184594B1 (hu)
HK (1) HK1048324B (hu)
HU (1) HU228252B1 (hu)
MX (1) MXPA02000639A (hu)
PT (1) PT1225180E (hu)
SK (1) SK287633B6 (hu)
UY (1) UY27126A1 (hu)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
ES2626268T3 (es) 2002-09-11 2017-07-24 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
SG162788A1 (en) 2005-06-14 2010-07-29 Amgen Inc Self-buffering protein formulations
US7879332B2 (en) * 2005-09-01 2011-02-01 Plasma Technologies, Llc Ultra-high yield intravenous immune globulin preparation
US20070049732A1 (en) * 2005-09-01 2007-03-01 Zurlo Eugene J Ultra-high yield intravenous immune globulin preparation
US8293242B2 (en) * 2005-09-01 2012-10-23 Plasma Technologies, Llc Ultra-high yield of alpha-1-anti-trypsin
JP2008094722A (ja) * 2006-10-05 2008-04-24 Benesis Corp 免疫グロブリン製剤の製造方法
US20080214795A1 (en) * 2007-02-14 2008-09-04 Amgen Inc. Method of isolating antibodies by precipitation
TWI532498B (zh) 2008-03-17 2016-05-11 巴克斯特保健公司 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法
NZ597809A (en) 2009-08-06 2014-05-30 Genentech Inc Method to improve virus removal in protein purification
AU2010296017C1 (en) 2009-09-17 2013-09-19 Takeda Pharmaceutical Company Limited Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof
JP5814951B2 (ja) * 2010-03-10 2015-11-17 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 免疫グロブリン溶液を精製するための方法
WO2013023362A1 (zh) * 2011-08-16 2013-02-21 深圳市卫武光明生物制品有限公司 静注巨细胞病毒人免疫球蛋白及其制备方法
ES2381828B1 (es) 2012-03-20 2012-11-16 Grifols, S.A. PROCEDIMIENTO PARA OBTENER UNA COMPOSICION DE IgG MEDIANTE TRATAMIENTO TERMICO
WO2015158776A1 (en) 2014-04-15 2015-10-22 Boehringer Ingelheim International Gmbh Methods, apparatuses, and systems for continuously inactivating a virus during manufacture of a biological product
MY172309A (en) 2014-06-12 2019-11-21 Biosyn Arzneimittel Gmbh Preparation methods for a novel generation of biological safe klh products used for cancer treatment, for the development of conjugated therapeutic vaccines and as challenging agents
ES2717709T3 (es) 2014-06-12 2019-06-24 Biosyn Arzneimittel Gmbh Métodos de preparación para una generación novedosa de productos de KLH biológicamente seguros usados para el tratamiento de cáncer, para el desarrollo de vacunas terapéuticas conjugadas y como agentes de exposición
JP6521351B2 (ja) 2014-10-14 2019-05-29 テックプロジェクトサービス株式会社 ウィルス不活化およびサンプリング装置
PL3215528T3 (pl) 2014-11-06 2020-01-31 F.Hoffmann-La Roche Ag Warianty regionu Fc ze zmodyfikowanym wiązaniem FcRn i sposoby stosowania
PT3135687T (pt) 2015-08-31 2019-05-21 Inst Grifols S A Método para preparação de imunoglobulinas
CA3012694A1 (en) 2016-02-03 2017-08-10 Plasma Technologies, Llc Methods for extracting proteins from a blood-based material
US11407981B2 (en) 2016-03-11 2022-08-09 Boehringer Ingelheim International Gmbh Methods for continuously inactivating a virus during manufacture of a protein
KR102372105B1 (ko) * 2016-09-26 2022-03-07 인스티투토 그리폴스, 에스.아. 면역글로블린의 제조방법
MX2019004580A (es) 2016-10-21 2019-08-12 Amgen Inc Formulaciones farmaceuticas y metodos para prepararlas.
US10815270B1 (en) 2019-09-20 2020-10-27 Plasma Technologies, Llc Compositions and methods for high efficiency protein precipitation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4164495A (en) * 1976-04-06 1979-08-14 Nordisk Insulinlaboratorium Method of recovering immunoglobulin using a polyol and an alkanoic acid
US4374763A (en) * 1979-09-17 1983-02-22 Morishita Pharmaceutical Co., Ltd. Method for producing gamma-globulin for use in intravenous administration and method for producing a pharmaceutical preparation thereof
EP0116571B2 (en) * 1982-08-30 1997-10-29 BAXTER INTERNATIONAL INC. (a Delaware corporation) Method for making gamma globulin-containing compositions
US5234685A (en) * 1983-03-16 1993-08-10 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of determining incompatibility-reaction-causing substances in blood products as well as a method of inactivating said incompatibility-reaction-causing substances
JP2547556B2 (ja) * 1987-02-06 1996-10-23 株式会社 ミドリ十字 ｒ−グロブリンの液状製剤
US5177194A (en) * 1990-02-01 1993-01-05 Baxter International, Inc. Process for purifying immune serum globulins
ES2129076T5 (es) * 1993-12-27 2003-05-16 Zlb Bioplasma Ag Procedimiento para la preparacion de un concentrado de inmunoglobulina g anti-d y composicion farmaceutica que lo contiene.
CA2232420A1 (en) * 1997-03-19 1998-09-19 The Green Cross Corporation Immunoglobulin preparation and preparation process thereof
IL121900A (en) * 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
CN1149100C (zh) * 1997-10-23 2004-05-12 三菱制药株式会社 可室温贮存的免疫球蛋白静脉注射制剂
UA64742C2 (uk) * 1997-12-24 2004-03-15 Альфа Терапевтик Корпорейшн СПОСІБ ОДЕРЖАННЯ РОЗЧИНУ <font face="Symbol">g</font>-ГЛОБУЛІНУ, ПРИЗНАЧЕНОГО ДЛЯ ВНУТРІШНЬОВЕННОГО ВВЕДЕННЯ, І ПРОДУКТ, ЩО ОДЕРЖУЄТЬСЯ У ЦЕЙ СПОСІБ (ВАРІАНТИ)
ES2527915T3 (es) * 1998-06-09 2015-02-02 Csl Behring Ag Producto de inmunoglobulina G (IgG) líquido
KR100501263B1 (ko) * 1998-06-09 2005-07-18 스태튼스 세룸 인스티튜트 정맥 주사용 면역글로불린의 제조 방법 및 그 외의 면역글로불린 제품
US6441144B1 (en) * 1999-05-20 2002-08-27 Alpha Therapeutic Corporation Method for repairing dual virally inactivated immune globulin for intravenous administration

Also Published As

Publication number Publication date
EP1225180A2 (en) 2002-07-24
MXPA02000639A (es) 2004-11-01
DE60224310T2 (de) 2009-01-08
JP2003002896A (ja) 2003-01-08
CZ2002131A3 (cs) 2002-09-11
EP1225180A3 (en) 2004-01-28
PT1225180E (pt) 2008-03-18
ATE382631T1 (de) 2008-01-15
US6875848B2 (en) 2005-04-05
ES2184594A1 (es) 2003-04-01
JP4070468B2 (ja) 2008-04-02
HUP0200103A2 (hu) 2003-08-28
US20020151688A1 (en) 2002-10-17
ES2295308T3 (es) 2008-04-16
HK1048324A1 (en) 2003-03-28
SK582002A3 (en) 2002-10-08
HU228252B1 (en) 2013-02-28
DE60224310D1 (de) 2008-02-14
UY27126A1 (es) 2002-07-31
AR032242A1 (es) 2003-10-29
EP1225180B1 (en) 2008-01-02
CZ300413B6 (cs) 2009-05-13
ES2184594B1 (es) 2004-01-01
HU0200103D0 (en) 2002-03-28
HK1048324B (zh) 2008-02-22
HUP0200103A3 (en) 2004-10-28

Similar Documents

Publication Publication Date Title
SK287633B6 (sk) Spôsob výroby humánneho gamaglobulínu G a humánny gamaglobulín G s inaktivovanými vírusmi
KR100501263B1 (ko) 정맥 주사용 면역글로불린의 제조 방법 및 그 외의 면역글로불린 제품
KR20070009995A (ko) 바이러스 안전성 면역글로불린을 제조하는 방법
JP2002517516A (ja) 静脈投与用免疫グロブリン及び他の免疫グロブリン生成物の製造法
US20060177909A1 (en) Preparation of immunoglobulin
JP6132839B2 (ja) 多価免疫グロブリン濃縮物の製造方法
RU2636049C2 (ru) СПОСОБ ПОЛУЧЕНИЯ КОМПОЗИЦИИ IgG ПОСРЕДСТВОМ ТЕПЛОВОЙ ОБРАБОТКИ
US10358462B2 (en) Method for the preparation of immunoglobulins
CN107880116B (zh) 用于制备免疫球蛋白的方法
AU2016231646B2 (en) Method for the preparation of immunoglobulins
CZ20014456A3 (cs) Způsob přípravy intravenózního immunoglobulinu a přípravku, který jej obsahuje
JP6370853B2 (ja) 免疫グロブリンの調製方法
US11884702B2 (en) Systems and methods for process scale isolation of immunoglobulin G
KR102372105B1 (ko) 면역글로블린의 제조방법
CA2943328C (en) Method for the preparation of immunoglobulins
RU2708394C2 (ru) Способ получения иммуноглобулинов
TWI712612B (zh) 製備免疫球蛋白溶液的方法
NZ724670A (en) Method for the preparation of immunoglobulins
NZ724670B2 (en) Method for the preparation of immunoglobulins
BR102016022107A2 (pt) Processo de preparação de imunoglobulinas

Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20220111