SK287477B6 - Spôsob prípravy 2-[5-(fluórfenyl)-3-pyridylmetylaminometyl]- chrománu - Google Patents

Spôsob prípravy 2-[5-(fluórfenyl)-3-pyridylmetylaminometyl]- chrománu Download PDF

Info

Publication number
SK287477B6
SK287477B6 SK1433-2003A SK14332003A SK287477B6 SK 287477 B6 SK287477 B6 SK 287477B6 SK 14332003 A SK14332003 A SK 14332003A SK 287477 B6 SK287477 B6 SK 287477B6
Authority
SK
Slovakia
Prior art keywords
fluorophenyl
aminomethylchroman
pyridylmethylaminomethyl
formula
salts
Prior art date
Application number
SK1433-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK14332003A3 (sk
Inventor
Heinz-Hermann Bokel
Steffen Neunfeld
Ludwig Gantzert
Ralf Knierieme
Elke Simon
Ralf Devant
Udo Helm
Helmut Reubold
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SK14332003A3 publication Critical patent/SK14332003A3/sk
Publication of SK287477B6 publication Critical patent/SK287477B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK1433-2003A 2001-04-26 2002-04-08 Spôsob prípravy 2-[5-(fluórfenyl)-3-pyridylmetylaminometyl]- chrománu SK287477B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10120619A DE10120619A1 (de) 2001-04-26 2001-04-26 2-(5-(4-Fluorphenyl)-3-pyridylmethylaminomethyl-chroman
PCT/EP2002/003857 WO2002088117A2 (de) 2001-04-26 2002-04-08 Verfahren zur herstellung von 2-[-5-(4-fluorphenyl)-3-pyridylmethylaminomethyl]-chroman

Publications (2)

Publication Number Publication Date
SK14332003A3 SK14332003A3 (sk) 2004-04-06
SK287477B6 true SK287477B6 (sk) 2010-11-08

Family

ID=7682908

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1433-2003A SK287477B6 (sk) 2001-04-26 2002-04-08 Spôsob prípravy 2-[5-(fluórfenyl)-3-pyridylmetylaminometyl]- chrománu

Country Status (24)

Country Link
US (1) US7045629B2 (es)
EP (1) EP1383763B1 (es)
JP (1) JP2004526797A (es)
KR (1) KR100839168B1 (es)
CN (1) CN100430391C (es)
AR (1) AR033262A1 (es)
AT (1) ATE306485T1 (es)
AU (1) AU2002257763B2 (es)
BR (1) BR0209179A (es)
CA (1) CA2445207C (es)
CZ (1) CZ301615B6 (es)
DE (2) DE10120619A1 (es)
DK (1) DK1383763T3 (es)
ES (1) ES2250647T3 (es)
HK (1) HK1077302A1 (es)
HU (1) HU229151B1 (es)
MX (1) MXPA03009684A (es)
MY (1) MY130616A (es)
PL (1) PL208705B1 (es)
RU (1) RU2288229C2 (es)
SI (1) SI1383763T1 (es)
SK (1) SK287477B6 (es)
WO (1) WO2002088117A2 (es)
ZA (1) ZA200309164B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4896518B2 (ja) * 2002-12-13 2012-03-14 ワイエム・バイオサイエンシズ・オーストラリア・ピーティーワイ・リミテッド ニコチンアミド系キナーゼ阻害薬
CA2597616A1 (en) * 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
TW200716595A (en) * 2005-04-22 2007-05-01 Wyeth Corp Chromane and chromene derivatives and uses thereof
ATE428416T1 (de) * 2005-06-21 2009-05-15 Merck Patent Gmbh Feste pharmazeutische zubereitung enthaltend (r)- (-)-2-ä5-(4-fluorophenyl)-3- pyridylmethylaminomethylü-chroman
NZ571706A (en) * 2006-04-18 2012-06-29 Abbott Lab Antagonists of the vanilloid receptor subtype 1 (VR1) and uses thereof
ES2574179T3 (es) * 2010-07-20 2016-06-15 Glaxo Group Limited Procedimiento para preparar derivados de pirano-[2,3-c]piridina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
FR2701479B1 (fr) 1993-02-11 1995-05-12 Pf Medicament Nouveaux dérivés hétérocycliques de l'aminométhyl-4 pipéridine, leur préparation et leur application en thérapeutique.
PL181385B1 (pl) * 1993-08-19 2001-07-31 Janssen Pharmaceutica Nv Nowe pochodne dihydrobenzopiranu o wlasciwosciach naczyniozwezajacych, kompozycja farmaceutyczna i sposób wytwarzania pochodnych dihydrobenzopiranu PL PL PL PL PL PL
GB9318431D0 (en) * 1993-09-06 1993-10-20 Boots Co Plc Therapeutic agents
DK0707007T3 (da) * 1994-10-14 2002-03-18 Merck Patent Gmbh Amino(thio)etherderivater som CNS-aktive midler
DE10005150A1 (de) 2000-02-07 2001-08-09 Merck Patent Gmbh Verfahren zur Herstellung von 5-Arylnicotinaldehyden

Also Published As

Publication number Publication date
WO2002088117A2 (de) 2002-11-07
CN100430391C (zh) 2008-11-05
RU2288229C2 (ru) 2006-11-27
RU2003132433A (ru) 2005-04-20
DK1383763T3 (da) 2006-02-06
US7045629B2 (en) 2006-05-16
MXPA03009684A (es) 2004-02-12
HK1077302A1 (en) 2006-02-10
EP1383763A2 (de) 2004-01-28
HUP0303969A3 (en) 2011-02-28
KR20040010616A (ko) 2004-01-31
HUP0303969A2 (hu) 2004-04-28
EP1383763B1 (de) 2005-10-12
JP2004526797A (ja) 2004-09-02
CZ20033214A3 (cs) 2004-02-18
ZA200309164B (en) 2004-09-29
ATE306485T1 (de) 2005-10-15
CA2445207A1 (en) 2002-11-07
BR0209179A (pt) 2004-08-03
SK14332003A3 (sk) 2004-04-06
PL208705B1 (pl) 2011-05-31
WO2002088117A3 (de) 2002-12-27
ES2250647T3 (es) 2006-04-16
CA2445207C (en) 2010-03-02
DE50204535D1 (de) 2006-02-23
HU229151B1 (hu) 2013-09-30
SI1383763T1 (sl) 2006-04-30
CN1622944A (zh) 2005-06-01
US20040138266A1 (en) 2004-07-15
PL363281A1 (en) 2004-11-15
CZ301615B6 (cs) 2010-05-05
AU2002257763B2 (en) 2007-03-15
MY130616A (en) 2007-07-31
DE10120619A1 (de) 2002-10-31
KR100839168B1 (ko) 2008-06-17
AR033262A1 (es) 2003-12-10

Similar Documents

Publication Publication Date Title
JP7287978B2 (ja) 二つの4-{[(2s)-2-{4-[5-クロロ-2-(1h-1,2,3-トリアゾール-1-イル)フェニル]-5-メトキシ-2-オキソピリジン-1(2h)-イル}ブタノイル]アミノ}-2-フルオロベンズアミド誘導体の調製方法
SK361392A3 (en) Azaheterocyclylmethyl-chromans, method for producing them, their use and pharmaceutical composition containing same
WO2007121389A2 (en) 4,4-disubstituted piperidine derivatives as nk-i and serotonin transporter inhibitors
EP1758862A1 (en) Aminopyridine derivatives as selective dopamine d3 agonists
KR100691735B1 (ko) 4-아미노메틸-3-알콕시이미노피롤리딘 메탄설폰산염의신규한 제조 방법
SK287477B6 (sk) Spôsob prípravy 2-[5-(fluórfenyl)-3-pyridylmetylaminometyl]- chrománu
AU706755B2 (en) Benzisothiazolyl-substituted aminomethylchromans
SK361292A3 (en) Piperidylmethyl-substituted chroman derivatives, process for producing them, their use and pharmaceutical composition containg same
KR101795790B1 (ko) 5-ht7 수용체에 작용하는 바이페닐 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 약학조성물
CN115960003A (zh) 一种重酒石酸间羟胺的合成方法
RU2729074C2 (ru) Способ очистки производного бензопирана, его кристаллическая форма и способ получения кристаллической формы
JP2741992B2 (ja) 3−アミノクロマン化合物鏡像異性体の合成方法
TW201348215A (zh) 雜環化合物
JPS63503384A (ja) 1‐置換(s)‐および(r)‐2‐アミノメチルピロリジン類の有効な立体保存的合成およびその中間体
WO2007035003A1 (ja) 光学活性なピペラジン化合物の製造方法
CZ303115B6 (cs) Zpusob výroby (2R,3R)-N,N-dimethyl-3-(3-hydroxyfenyl)-2-methylpentylaminu
CZ421999A3 (cs) Nový způsob

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20120408