SK286821B6 - Bunkový systém na in vivo expresiu interferónu beta a farmaceutický prípravok obsahujúci tento systém - Google Patents

Bunkový systém na in vivo expresiu interferónu beta a farmaceutický prípravok obsahujúci tento systém Download PDF

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Publication number
SK286821B6
SK286821B6 SK248-2000A SK2482000A SK286821B6 SK 286821 B6 SK286821 B6 SK 286821B6 SK 2482000 A SK2482000 A SK 2482000A SK 286821 B6 SK286821 B6 SK 286821B6
Authority
SK
Slovakia
Prior art keywords
interferon
cells
gene
vector
tumor
Prior art date
Application number
SK248-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK2482000A3 (en
Inventor
James G. Barsoum
Xiao-Qiang Qin
Original Assignee
Biogen Idec Ma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Ma Inc. filed Critical Biogen Idec Ma Inc.
Publication of SK2482000A3 publication Critical patent/SK2482000A3/sk
Publication of SK286821B6 publication Critical patent/SK286821B6/sk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK248-2000A 1997-08-29 1998-08-25 Bunkový systém na in vivo expresiu interferónu beta a farmaceutický prípravok obsahujúci tento systém SK286821B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5725497P 1997-08-29 1997-08-29
PCT/US1998/017606 WO1999010516A2 (en) 1997-08-29 1998-08-25 Methods and compositions for therapies using genes encoding secreted proteins such as interferon-beta

Publications (2)

Publication Number Publication Date
SK2482000A3 SK2482000A3 (en) 2000-08-14
SK286821B6 true SK286821B6 (sk) 2009-06-05

Family

ID=22009467

Family Applications (1)

Application Number Title Priority Date Filing Date
SK248-2000A SK286821B6 (sk) 1997-08-29 1998-08-25 Bunkový systém na in vivo expresiu interferónu beta a farmaceutický prípravok obsahujúci tento systém

Country Status (25)

Country Link
EP (1) EP1007717B8 (is)
JP (3) JP4124565B2 (is)
KR (1) KR100699285B1 (is)
CN (1) CN100342019C (is)
AT (1) ATE316145T1 (is)
AU (1) AU740428B2 (is)
BR (1) BR9812138A (is)
CA (1) CA2300480C (is)
CY (1) CY1105029T1 (is)
CZ (2) CZ297314B6 (is)
DE (1) DE69833264T2 (is)
DK (1) DK1007717T3 (is)
EA (1) EA003256B1 (is)
EE (1) EE04873B1 (is)
ES (1) ES2257817T3 (is)
HK (1) HK1029599A1 (is)
HU (1) HU224422B1 (is)
IL (2) IL134593A0 (is)
IS (1) IS2318B (is)
NO (1) NO20000990L (is)
NZ (1) NZ503401A (is)
PT (1) PT1007717E (is)
SK (1) SK286821B6 (is)
TR (1) TR200000532T2 (is)
WO (1) WO1999010516A2 (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1363676B1 (en) 2001-01-22 2007-03-28 Biogen Idec MA Inc. Method of enhancing delivery of a therapeutic nucleic acid
US8058248B2 (en) * 2001-04-26 2011-11-15 The United States Of America As Represented By The Secretary Of Agriculture Foot and mouth disease virus vaccine comprising interferons
CN1388248A (zh) * 2001-05-25 2003-01-01 钱其军 高效表达干扰素的肿瘤细胞内特异性增殖的腺病毒及其构建方法
EP1835032A1 (en) * 2006-03-14 2007-09-19 Université de Liège A self-inactivating recombinant lentiviral vector for the inhibition of HIV replication
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
MD24Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
MD23Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
MD36Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
CN103505722B (zh) * 2012-06-19 2016-04-13 苏州丁孚靶点生物技术有限公司 干扰素在治疗/预防对常规抗肿瘤疗法有抗性的肿瘤中的用途及相关的产品和方法
WO2017214706A1 (en) * 2016-06-15 2017-12-21 Tissue Regeneration Therapeutics Inc. Anti-cancer use of genetically modified human umbilical cord perivascular cells (hucpvc)
KR20220025757A (ko) * 2019-06-01 2022-03-03 시벡 바이오테크놀로지스, 엘엘씨 진핵 세포에 유전자 편집 시스템을 전달하기 위한 박테리아 플랫폼

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2122519C (en) * 1994-04-29 2001-02-20 Rudolf Edgar Dr. Falk Cancer treatment and metastasis prevention
EP0707071B1 (en) * 1994-08-16 2003-07-30 Crucell Holland B.V. Recombinant vectors derived from adenovirus for use in gene therapy
US5952221A (en) * 1996-03-06 1999-09-14 Avigen, Inc. Adeno-associated virus vectors comprising a first and second nucleic acid sequence

Also Published As

Publication number Publication date
JP2005225888A (ja) 2005-08-25
TR200000532T2 (tr) 2000-11-21
SK2482000A3 (en) 2000-08-14
AU740428B2 (en) 2001-11-01
BR9812138A (pt) 2000-07-18
DK1007717T3 (da) 2006-05-29
IL134593A (en) 2007-06-17
EA003256B1 (ru) 2003-02-27
EE04873B1 (et) 2007-08-15
IS2318B (is) 2007-11-15
WO1999010516A3 (en) 1999-05-06
EP1007717A2 (en) 2000-06-14
DE69833264D1 (de) 2006-04-06
HUP0002913A2 (hu) 2000-12-28
HK1029599A1 (en) 2001-04-06
HUP0002913A3 (en) 2003-08-28
EE200000102A (et) 2000-12-15
NZ503401A (en) 2003-01-31
CN100342019C (zh) 2007-10-10
CZ299095B6 (cs) 2008-04-23
CA2300480A1 (en) 1999-03-04
AU9205198A (en) 1999-03-16
JP2004155786A (ja) 2004-06-03
EP1007717B1 (en) 2006-01-18
IL134593A0 (en) 2001-04-30
PT1007717E (pt) 2006-06-30
HU224422B1 (hu) 2005-08-29
EP1007717B8 (en) 2006-05-03
JP2001514010A (ja) 2001-09-11
NO20000990D0 (no) 2000-02-28
KR20010023511A (ko) 2001-03-26
CA2300480C (en) 2010-01-05
IS5374A (is) 2000-02-11
WO1999010516A2 (en) 1999-03-04
CZ2000733A3 (cs) 2000-06-14
JP4219335B2 (ja) 2009-02-04
NO20000990L (no) 2000-05-02
ATE316145T1 (de) 2006-02-15
CN1271391A (zh) 2000-10-25
EA200000270A1 (ru) 2000-10-30
JP4124565B2 (ja) 2008-07-23
CZ297314B6 (cs) 2006-11-15
DE69833264T2 (de) 2006-09-28
ES2257817T3 (es) 2006-08-01
CY1105029T1 (el) 2010-03-03
JP3953458B2 (ja) 2007-08-08
KR100699285B1 (ko) 2007-03-26

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100825