ATE316145T1 - Verfahren und zusammensetzungen für die krebstherapie unter verwendung von interferon- beta codierenden genen - Google Patents

Verfahren und zusammensetzungen für die krebstherapie unter verwendung von interferon- beta codierenden genen

Info

Publication number
ATE316145T1
ATE316145T1 AT98944526T AT98944526T ATE316145T1 AT E316145 T1 ATE316145 T1 AT E316145T1 AT 98944526 T AT98944526 T AT 98944526T AT 98944526 T AT98944526 T AT 98944526T AT E316145 T1 ATE316145 T1 AT E316145T1
Authority
AT
Austria
Prior art keywords
methods
interferon
compositions
cancer therapy
coding genes
Prior art date
Application number
AT98944526T
Other languages
English (en)
Inventor
James G Barsoum
Xiao-Qiang Qin
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Application granted granted Critical
Publication of ATE316145T1 publication Critical patent/ATE316145T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98944526T 1997-08-29 1998-08-25 Verfahren und zusammensetzungen für die krebstherapie unter verwendung von interferon- beta codierenden genen ATE316145T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5725497P 1997-08-29 1997-08-29

Publications (1)

Publication Number Publication Date
ATE316145T1 true ATE316145T1 (de) 2006-02-15

Family

ID=22009467

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98944526T ATE316145T1 (de) 1997-08-29 1998-08-25 Verfahren und zusammensetzungen für die krebstherapie unter verwendung von interferon- beta codierenden genen

Country Status (25)

Country Link
EP (1) EP1007717B8 (de)
JP (3) JP4124565B2 (de)
KR (1) KR100699285B1 (de)
CN (1) CN100342019C (de)
AT (1) ATE316145T1 (de)
AU (1) AU740428B2 (de)
BR (1) BR9812138A (de)
CA (1) CA2300480C (de)
CY (1) CY1105029T1 (de)
CZ (2) CZ299095B6 (de)
DE (1) DE69833264T2 (de)
DK (1) DK1007717T3 (de)
EA (1) EA003256B1 (de)
EE (1) EE04873B1 (de)
ES (1) ES2257817T3 (de)
HK (1) HK1029599A1 (de)
HU (1) HU224422B1 (de)
IL (2) IL134593A0 (de)
IS (1) IS2318B (de)
NO (1) NO20000990L (de)
NZ (1) NZ503401A (de)
PT (1) PT1007717E (de)
SK (1) SK286821B6 (de)
TR (1) TR200000532T2 (de)
WO (1) WO1999010516A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002056918A2 (en) * 2001-01-22 2002-07-25 Biogen, Inc. Method of enhancing delivery of a therapeutic nucleic acid
US8058248B2 (en) * 2001-04-26 2011-11-15 The United States Of America As Represented By The Secretary Of Agriculture Foot and mouth disease virus vaccine comprising interferons
CN1388248A (zh) * 2001-05-25 2003-01-01 钱其军 高效表达干扰素的肿瘤细胞内特异性增殖的腺病毒及其构建方法
EP1835032A1 (de) * 2006-03-14 2007-09-19 Université de Liège Selbst-inaktivierender rekombinanter lentiviraler Vektor zur Inhibierung von HIV
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
MD36Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
MD24Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
MD23Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
CN103505722B (zh) * 2012-06-19 2016-04-13 苏州丁孚靶点生物技术有限公司 干扰素在治疗/预防对常规抗肿瘤疗法有抗性的肿瘤中的用途及相关的产品和方法
WO2017214706A1 (en) * 2016-06-15 2017-12-21 Tissue Regeneration Therapeutics Inc. Anti-cancer use of genetically modified human umbilical cord perivascular cells (hucpvc)
JP2022534437A (ja) * 2019-06-01 2022-07-29 シベック バイオテクノロジーズ,リミティド ライアビリティ カンパニー 真核細胞への遺伝子編集システムの送達のための細菌プラットフォーム

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2122519C (en) * 1994-04-29 2001-02-20 Rudolf Edgar Dr. Falk Cancer treatment and metastasis prevention
EP0707071B1 (de) * 1994-08-16 2003-07-30 Crucell Holland B.V. Von Adenovirus abgeleitete rekombinante Vektoren, für Gentherapie
US5952221A (en) * 1996-03-06 1999-09-14 Avigen, Inc. Adeno-associated virus vectors comprising a first and second nucleic acid sequence

Also Published As

Publication number Publication date
KR100699285B1 (ko) 2007-03-26
CN100342019C (zh) 2007-10-10
CZ299095B6 (cs) 2008-04-23
ES2257817T3 (es) 2006-08-01
JP3953458B2 (ja) 2007-08-08
EE200000102A (et) 2000-12-15
KR20010023511A (ko) 2001-03-26
CA2300480A1 (en) 1999-03-04
CY1105029T1 (el) 2010-03-03
JP4219335B2 (ja) 2009-02-04
HK1029599A1 (en) 2001-04-06
EA003256B1 (ru) 2003-02-27
NZ503401A (en) 2003-01-31
EE04873B1 (et) 2007-08-15
HU224422B1 (hu) 2005-08-29
JP2004155786A (ja) 2004-06-03
NO20000990D0 (no) 2000-02-28
PT1007717E (pt) 2006-06-30
DE69833264D1 (de) 2006-04-06
JP2005225888A (ja) 2005-08-25
NO20000990L (no) 2000-05-02
EP1007717B8 (de) 2006-05-03
BR9812138A (pt) 2000-07-18
DE69833264T2 (de) 2006-09-28
IL134593A (en) 2007-06-17
SK2482000A3 (en) 2000-08-14
IS2318B (is) 2007-11-15
CZ297314B6 (cs) 2006-11-15
IS5374A (is) 2000-02-11
AU740428B2 (en) 2001-11-01
DK1007717T3 (da) 2006-05-29
JP4124565B2 (ja) 2008-07-23
HUP0002913A2 (hu) 2000-12-28
WO1999010516A3 (en) 1999-05-06
EA200000270A1 (ru) 2000-10-30
EP1007717A2 (de) 2000-06-14
SK286821B6 (sk) 2009-06-05
TR200000532T2 (tr) 2000-11-21
AU9205198A (en) 1999-03-16
IL134593A0 (en) 2001-04-30
EP1007717B1 (de) 2006-01-18
CZ2000733A3 (cs) 2000-06-14
WO1999010516A2 (en) 1999-03-04
CA2300480C (en) 2010-01-05
HUP0002913A3 (en) 2003-08-28
CN1271391A (zh) 2000-10-25
JP2001514010A (ja) 2001-09-11

Similar Documents

Publication Publication Date Title
CY1105029T1 (el) Μεθοδοι και συνθεσεις για θεραπειες καρκινου χρησιμοποιωντας γονιδια που κωδικοποιουν εκκρινομενες πρωτεϊνες οπως ιντερφερονη-βητα
ATE197719T1 (de) Verwendung von mesothelialen zellen in der gentherapie
DE69230993T2 (de) Rekombinante viren vektoren zur expression in muskelzellen
DE69435096D1 (de) Zusammensetzung zur in vivo erzeugung von therapeutischen produkten
DE69334062D1 (de) In vitro Aktivierung von cytotoxischen T Zellen
IT1298487B1 (it) Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale,
ATE88500T1 (de) Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel.
ATE174629T1 (de) Herstellung von proteinen mittels protein 7b2
TR199901190T2 (xx) Interferon-(alfa) N�kleik asitlerinin verilmesi ve sentezlenmesi i�in y�ntemler ve bile�imler.
ATE309382T1 (de) Rekombinante adenovirenvektoren zur gentherapie der menschlichen krebse
DE69910809D1 (de) Verwendung von OmpA Enterobakterproteinen um zielgerichtet Antigen-Präsentierende Zellen anzusteuern
DE60035504D1 (de) Verfahren für die verabreichung von heilmitteln mittels einer dextrinlösung
DE69916829D1 (de) Genetisch veränderte fibroblasten und ihre verwendung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1007717

Country of ref document: EP