SK286340B6 - Polymorph of clopidogrel hydrogen sulphate, a method for the production thereof, and a pharmaceutical composition comprising the same - Google Patents

Polymorph of clopidogrel hydrogen sulphate, a method for the production thereof, and a pharmaceutical composition comprising the same Download PDF

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Publication number
SK286340B6
SK286340B6 SK1909-2000A SK19092000A SK286340B6 SK 286340 B6 SK286340 B6 SK 286340B6 SK 19092000 A SK19092000 A SK 19092000A SK 286340 B6 SK286340 B6 SK 286340B6
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SK
Slovakia
Prior art keywords
hydrogen sulphate
clopidogrel hydrogen
clopidogrel
polymorph
crystalline
Prior art date
Application number
SK1909-2000A
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English (en)
Slovak (sk)
Other versions
SK19092000A3 (sk
Inventor
Andre Bousquet
Bertrand Castro
Jean Saint-Germain
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of SK19092000A3 publication Critical patent/SK19092000A3/sk
Publication of SK286340B6 publication Critical patent/SK286340B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1909-2000A 1998-06-15 1999-06-10 Polymorph of clopidogrel hydrogen sulphate, a method for the production thereof, and a pharmaceutical composition comprising the same SK286340B6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9807464A FR2779726B1 (fr) 1998-06-15 1998-06-15 Forme polymorphe de l'hydrogenosulfate de clopidogrel
PCT/FR1999/001371 WO1999065915A1 (fr) 1998-06-15 1999-06-10 Forme polymorphe de l'hydrogenosulfate de clopidogrel

Publications (2)

Publication Number Publication Date
SK19092000A3 SK19092000A3 (sk) 2001-05-10
SK286340B6 true SK286340B6 (en) 2008-07-07

Family

ID=9527349

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1909-2000A SK286340B6 (en) 1998-06-15 1999-06-10 Polymorph of clopidogrel hydrogen sulphate, a method for the production thereof, and a pharmaceutical composition comprising the same

Country Status (44)

Country Link
US (2) US6429210B1 (xx)
EP (1) EP1087976B1 (xx)
JP (1) JP3641584B2 (xx)
KR (1) KR100511238B1 (xx)
CN (1) CN1128805C (xx)
AP (1) AP1344A (xx)
AR (1) AR014854A1 (xx)
AT (1) ATE222256T1 (xx)
AU (1) AU752170B2 (xx)
BG (1) BG64508B1 (xx)
BR (1) BR9911219A (xx)
CA (1) CA2334870C (xx)
CO (1) CO5040084A1 (xx)
CZ (1) CZ299654B6 (xx)
DE (1) DE69902536T2 (xx)
DK (1) DK1087976T3 (xx)
DZ (1) DZ2817A1 (xx)
EA (1) EA002386B1 (xx)
EE (1) EE03972B1 (xx)
EG (1) EG24015A (xx)
ES (1) ES2181439T3 (xx)
FR (1) FR2779726B1 (xx)
HK (1) HK1033829A1 (xx)
HR (1) HRP20000863B1 (xx)
HU (1) HU225871B1 (xx)
ID (1) ID28264A (xx)
IL (2) IL139790A0 (xx)
IS (1) IS2469B (xx)
ME (1) ME00686B (xx)
MY (1) MY129439A (xx)
NO (1) NO327161B1 (xx)
NZ (1) NZ507914A (xx)
OA (1) OA11567A (xx)
PL (1) PL201894B1 (xx)
PT (1) PT1087976E (xx)
RS (1) RS49870B (xx)
SA (1) SA99200321B1 (xx)
SK (1) SK286340B6 (xx)
TR (1) TR200003417T2 (xx)
TW (1) TW562805B (xx)
UA (1) UA70323C2 (xx)
UY (1) UY25693A1 (xx)
WO (1) WO1999065915A1 (xx)
ZA (1) ZA200006386B (xx)

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Also Published As

Publication number Publication date
CA2334870A1 (en) 1999-12-23
PT1087976E (pt) 2002-11-29
AP1344A (en) 2004-12-15
FR2779726A1 (fr) 1999-12-17
HU225871B1 (en) 2007-11-28
US20020198229A1 (en) 2002-12-26
HUP0104343A2 (hu) 2002-03-28
AP2000001979A0 (en) 2000-12-31
EE200000745A (et) 2002-04-15
NO20006395D0 (no) 2000-12-14
HRP20000863A2 (en) 2001-10-31
ME00686B (me) 2008-08-07
CZ299654B6 (cs) 2008-10-08
IS2469B (is) 2008-12-15
JP3641584B2 (ja) 2005-04-20
US6429210B1 (en) 2002-08-06
AU4048399A (en) 2000-01-05
ES2181439T3 (es) 2003-02-16
EE03972B1 (et) 2003-02-17
AU752170B2 (en) 2002-09-05
SA99200321B1 (ar) 2006-10-11
AR014854A1 (es) 2001-04-11
TR200003417T2 (tr) 2001-03-21
ATE222256T1 (de) 2002-08-15
ZA200006386B (en) 2001-05-07
PL344998A1 (en) 2001-11-19
NO327161B1 (no) 2009-05-04
KR20010052835A (ko) 2001-06-25
IS5716A (is) 2000-11-17
CN1305483A (zh) 2001-07-25
SK19092000A3 (sk) 2001-05-10
EP1087976A1 (fr) 2001-04-04
YU77700A (sh) 2003-04-30
IL139790A (en) 2006-10-05
HUP0104343A3 (en) 2003-03-28
NZ507914A (en) 2002-11-26
BG104987A (en) 2001-11-30
IL139790A0 (en) 2002-02-10
WO1999065915A1 (fr) 1999-12-23
DE69902536T2 (de) 2003-03-13
PL201894B1 (pl) 2009-05-29
DK1087976T3 (da) 2002-12-02
CO5040084A1 (es) 2001-05-29
NO20006395L (no) 2001-02-15
US6504030B1 (en) 2003-01-07
UA70323C2 (uk) 2004-10-15
DZ2817A1 (fr) 2004-06-02
JP2002518399A (ja) 2002-06-25
OA11567A (en) 2004-05-24
MY129439A (en) 2007-04-30
HRP20000863B1 (en) 2003-04-30
FR2779726B1 (fr) 2001-05-18
DE69902536D1 (en) 2002-09-19
EA200001187A1 (ru) 2001-08-27
EA002386B1 (ru) 2002-04-25
BG64508B1 (bg) 2005-05-31
CA2334870C (en) 2005-03-15
RS49870B (sr) 2008-08-07
UY25693A1 (es) 2000-03-31
EG24015A (en) 2008-03-24
CZ20004637A3 (cs) 2001-04-11
ID28264A (id) 2001-05-10
HK1033829A1 (en) 2001-09-28
KR100511238B1 (ko) 2005-08-31
BR9911219A (pt) 2001-03-06
EP1087976B1 (fr) 2002-08-14
TW562805B (en) 2003-11-21
CN1128805C (zh) 2003-11-26

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