SK285594B6 - Gama-karbolín, spôsob jeho prípravy a kompozícia s jeho obsahom - Google Patents
Gama-karbolín, spôsob jeho prípravy a kompozícia s jeho obsahom Download PDFInfo
- Publication number
- SK285594B6 SK285594B6 SK299-2000A SK2992000A SK285594B6 SK 285594 B6 SK285594 B6 SK 285594B6 SK 2992000 A SK2992000 A SK 2992000A SK 285594 B6 SK285594 B6 SK 285594B6
- Authority
- SK
- Slovakia
- Prior art keywords
- formula
- alkyl
- radical
- hydrogen
- gamma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97202761A EP0905136A1 (en) | 1997-09-08 | 1997-09-08 | Tetrahydro gamma-carbolines |
| PCT/EP1998/005710 WO1999012926A1 (en) | 1997-09-08 | 1998-09-01 | Tetrahydro gamma-carbolines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK2992000A3 SK2992000A3 (en) | 2001-03-12 |
| SK285594B6 true SK285594B6 (sk) | 2007-04-05 |
Family
ID=8228715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK299-2000A SK285594B6 (sk) | 1997-09-08 | 1998-09-01 | Gama-karbolín, spôsob jeho prípravy a kompozícia s jeho obsahom |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US6303614B1 (cs) |
| EP (2) | EP0905136A1 (cs) |
| JP (1) | JP2001515899A (cs) |
| KR (1) | KR100603896B1 (cs) |
| CN (1) | CN1110496C (cs) |
| AT (1) | ATE243209T1 (cs) |
| AU (1) | AU752410B2 (cs) |
| BR (1) | BR9811769A (cs) |
| CA (1) | CA2301807A1 (cs) |
| CZ (1) | CZ297220B6 (cs) |
| DE (1) | DE69815700T2 (cs) |
| EE (1) | EE04496B1 (cs) |
| ES (1) | ES2202902T3 (cs) |
| HK (1) | HK1029107A1 (cs) |
| HR (1) | HRP20000108A2 (cs) |
| HU (1) | HUP0003577A3 (cs) |
| ID (1) | ID23954A (cs) |
| IL (1) | IL134894A (cs) |
| MY (1) | MY129176A (cs) |
| NO (1) | NO315236B1 (cs) |
| NZ (1) | NZ503096A (cs) |
| PL (1) | PL191863B1 (cs) |
| RU (1) | RU2208614C2 (cs) |
| SK (1) | SK285594B6 (cs) |
| TR (1) | TR200000616T2 (cs) |
| TW (1) | TW531539B (cs) |
| WO (1) | WO1999012926A1 (cs) |
| ZA (1) | ZA988161B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1882590B (zh) * | 2003-09-17 | 2014-03-05 | 詹森药业有限公司 | 作为血清素受体调节剂的稠合杂环化合物 |
| DK1668014T3 (da) * | 2003-09-17 | 2009-04-20 | Janssen Pharmaceutica Nv | Kondenserede heterocykliske forbindelser som serotoninreceptormodulatorer |
| EP1944306A1 (en) * | 2003-09-17 | 2008-07-16 | Janssen Pharmaceutica, N.V. | Fused heterocyclic compounds as serotonin receptor modulators |
| US7601734B2 (en) | 2004-04-12 | 2009-10-13 | Taisho Pharmaceutical Co., Ltd. | Cyclic amine compound |
| CN101120002A (zh) | 2005-02-17 | 2008-02-06 | 惠氏公司 | 环烷基稠合的吲哚、苯并噻吩、苯并呋喃和茚衍生物 |
| FR2885905A1 (fr) * | 2005-05-23 | 2006-11-24 | Trophos Sa | Nouveaux composes chimiques et leurs utilisations comme medicament |
| WO2007009485A1 (en) * | 2005-07-22 | 2007-01-25 | Pharma C S.A. | Substituted 8-phenoxy-y-carboline derivatives with 5ht1 activity |
| CN101360720A (zh) * | 2005-11-15 | 2009-02-04 | 阿斯利康(瑞典)有限公司 | 新颖的2-氨基嘧啶酮衍生物及其用途 |
| US7845535B2 (en) * | 2006-10-06 | 2010-12-07 | Tyco Healthcare Group Lp | Surgical instrument having a plastic surface |
| AU2008302751A1 (en) * | 2007-09-20 | 2009-03-26 | D2E, Llc | Fluoro-containing derivatives of hydrogenated pyrido[4,3-b]indoles with neuroprotective and cognition enhancing properties, process for preparing, and use |
| EP2236511A4 (en) | 2007-12-21 | 2011-04-13 | Alla Chem Llc | LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF |
| RU2374245C1 (ru) | 2008-08-22 | 2009-11-27 | Андрей Александрович Иващенко | Лиганд с широким спектром одновременной рецепторной активности, фармацевтическая композиция, способ ее получения и лекарственное средство |
| CN105399674B (zh) | 2015-12-31 | 2017-02-15 | 青岛清原化合物有限公司 | 吡唑类化合物或其盐、制备方法、除草剂组合物及用途 |
| CN106631941B (zh) * | 2016-12-30 | 2018-09-28 | 青岛瀚生生物科技股份有限公司 | 一种2-甲基-3氯苯基甲硫醚的制备方法 |
| GB201704325D0 (en) * | 2017-03-17 | 2017-05-03 | Argonaut Therapeutics Ltd | Compounds |
| CN110698474B (zh) * | 2019-11-14 | 2021-11-02 | 福州大学 | 一种α位取代四氢-γ-咔啉类化合物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3410286C2 (de) * | 1984-03-21 | 1986-01-23 | Fresenius AG, 6380 Bad Homburg | Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens |
| US4672117A (en) * | 1985-09-16 | 1987-06-09 | American Home Products Corporation | Antipsychotic gamma-carbolines |
| US4798896A (en) * | 1988-01-19 | 1989-01-17 | American Home Products Corporation | Antipsychotic gamma-carboline N-oxides |
| ES2204932T3 (es) * | 1994-09-12 | 2004-05-01 | Eli Lilly And Company Limited | Moduladores serotonergicos. |
-
1997
- 1997-09-08 EP EP97202761A patent/EP0905136A1/en not_active Withdrawn
-
1998
- 1998-09-01 CZ CZ20000726A patent/CZ297220B6/cs not_active IP Right Cessation
- 1998-09-01 CN CN98808818A patent/CN1110496C/zh not_active Expired - Fee Related
- 1998-09-01 AT AT98951365T patent/ATE243209T1/de not_active IP Right Cessation
- 1998-09-01 WO PCT/EP1998/005710 patent/WO1999012926A1/en active IP Right Grant
- 1998-09-01 CA CA002301807A patent/CA2301807A1/en not_active Abandoned
- 1998-09-01 DE DE69815700T patent/DE69815700T2/de not_active Expired - Fee Related
- 1998-09-01 PL PL339143A patent/PL191863B1/pl not_active IP Right Cessation
- 1998-09-01 EE EEP200000059A patent/EE04496B1/xx not_active IP Right Cessation
- 1998-09-01 IL IL13489498A patent/IL134894A/xx not_active IP Right Cessation
- 1998-09-01 ES ES98951365T patent/ES2202902T3/es not_active Expired - Lifetime
- 1998-09-01 JP JP2000510733A patent/JP2001515899A/ja not_active Withdrawn
- 1998-09-01 RU RU2000109310/04A patent/RU2208614C2/ru not_active IP Right Cessation
- 1998-09-01 KR KR1020007000970A patent/KR100603896B1/ko not_active IP Right Cessation
- 1998-09-01 AU AU97421/98A patent/AU752410B2/en not_active Ceased
- 1998-09-01 US US09/508,240 patent/US6303614B1/en not_active Expired - Fee Related
- 1998-09-01 EP EP98951365A patent/EP1015451B1/en not_active Expired - Lifetime
- 1998-09-01 ID IDW20000432A patent/ID23954A/id unknown
- 1998-09-01 NZ NZ503096A patent/NZ503096A/en unknown
- 1998-09-01 TR TR2000/00616T patent/TR200000616T2/xx unknown
- 1998-09-01 BR BR9811769-6A patent/BR9811769A/pt not_active Application Discontinuation
- 1998-09-01 SK SK299-2000A patent/SK285594B6/sk unknown
- 1998-09-02 TW TW087114508A patent/TW531539B/zh not_active IP Right Cessation
- 1998-09-07 ZA ZA9808161A patent/ZA988161B/xx unknown
- 1998-09-07 MY MYPI98004080A patent/MY129176A/en unknown
- 1998-09-08 HU HU0003577A patent/HUP0003577A3/hu unknown
-
2000
- 2000-02-14 NO NO20000737A patent/NO315236B1/no unknown
- 2000-02-29 HR HR20000108A patent/HRP20000108A2/xx not_active Application Discontinuation
- 2000-11-10 HK HK00107165A patent/HK1029107A1/xx not_active IP Right Cessation
-
2001
- 2001-08-15 US US09/930,005 patent/US6506768B2/en not_active Expired - Fee Related
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