SK285584B6 - Použitie 11-(4-piperidylidén)-5H-benzo[5,6]-cyklohepta[1,2- b]pyridínovej zlúčeniny ako inhibítora farnezyl-proteíntransferázy na výrobu liečiva na liečenie proliferačného ochorenia - Google Patents
Použitie 11-(4-piperidylidén)-5H-benzo[5,6]-cyklohepta[1,2- b]pyridínovej zlúčeniny ako inhibítora farnezyl-proteíntransferázy na výrobu liečiva na liečenie proliferačného ochorenia Download PDFInfo
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- SK285584B6 SK285584B6 SK898-2000A SK8982000A SK285584B6 SK 285584 B6 SK285584 B6 SK 285584B6 SK 8982000 A SK8982000 A SK 8982000A SK 285584 B6 SK285584 B6 SK 285584B6
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- cancer
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- paclitaxel
- proliferative disease
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Landscapes
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| US99602797A | 1997-12-22 | 1997-12-22 | |
| US14352998A | 1998-08-28 | 1998-08-28 | |
| US18196998A | 1998-10-29 | 1998-10-29 | |
| PCT/US1998/026224 WO1999032114A1 (en) | 1997-12-22 | 1998-12-21 | Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases |
Publications (2)
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| SK8982000A3 SK8982000A3 (en) | 2001-04-09 |
| SK285584B6 true SK285584B6 (sk) | 2007-04-05 |
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| SK898-2000A SK285584B6 (sk) | 1997-12-22 | 1998-12-21 | Použitie 11-(4-piperidylidén)-5H-benzo[5,6]-cyklohepta[1,2- b]pyridínovej zlúčeniny ako inhibítora farnezyl-proteíntransferázy na výrobu liečiva na liečenie proliferačného ochorenia |
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| HU (1) | HUP0102473A3 (enExample) |
| IL (1) | IL136462A0 (enExample) |
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| NO (1) | NO326832B1 (enExample) |
| NZ (1) | NZ504928A (enExample) |
| PE (1) | PE20000042A1 (enExample) |
| PT (1) | PT1041985E (enExample) |
| SK (1) | SK285584B6 (enExample) |
| TW (1) | TW581763B (enExample) |
| WO (1) | WO1999032114A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787327B1 (fr) * | 1998-12-21 | 2003-01-17 | Aventis Pharma Sa | Compositions contenant des inhibiteurs de farnesyle transferase |
| DE60016625T2 (de) * | 1999-11-09 | 2005-12-22 | Societe De Conseils De Recherches Et D'applications Scientifiques(S.C.R.A.S.) | Zusammensetzung enthaltend einen inhibitor der signaltransduktion von heterotrimerischen g-proteinen in kombination mit einem anderen anti-krebs-mittel zu einer therapeutischen verwendung in der krebsbehandlung |
| AU2292801A (en) * | 1999-12-22 | 2001-07-03 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Compositions and methods for treatment of breast cancer |
| US20030186925A1 (en) * | 2000-02-29 | 2003-10-02 | Palmer Peter Albert | Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives |
| EP1261348A2 (en) * | 2000-02-29 | 2002-12-04 | Janssen Pharmaceutica N.V. | Combinations of a farnesyl protein transferase inhibitor with nitrogen mustard or nitrosourea alkylating agents |
| WO2001064197A2 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives |
| WO2001064226A2 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with platinum compounds |
| WO2001064196A2 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with vinca alkaloids |
| EP1267871A2 (en) * | 2000-02-29 | 2003-01-02 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives |
| TWI310684B (en) | 2000-03-27 | 2009-06-11 | Bristol Myers Squibb Co | Synergistic pharmaceutical kits for treating cancer |
| US6645966B2 (en) * | 2001-01-22 | 2003-11-11 | Schering Corporation | Treatment of malaria with farnesyl protein transferase inhibitors |
| JP4969016B2 (ja) * | 2001-02-15 | 2012-07-04 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 抗エストロゲン剤とファルネシルプロテイントランスフェラーゼ阻害剤の組み合わせ物 |
| HUP0402401A2 (hu) * | 2001-11-30 | 2005-03-29 | Schering Corp. | Rák kezelésére szolgáló eljárások egy FPT inhibitor és daganatellenes szerek felhasználásával |
| EP1453513A1 (en) * | 2001-12-03 | 2004-09-08 | Schering Corporation | Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer |
| WO2008022535A1 (fr) * | 2006-08-09 | 2008-02-28 | Tian Jin Tasly Group Co., Ltd. | Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique |
| CN105198758A (zh) * | 2015-09-22 | 2015-12-30 | 湖南大学 | 一种高纯度(z)-他莫昔酚的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| AU665341B2 (en) * | 1990-12-18 | 1996-01-04 | Wellcome Foundation Limited, The | Agents for potentiating the effects of antitumor agents and combating multiple drug resistance |
| JP2767176B2 (ja) * | 1992-12-15 | 1998-06-18 | 大塚製薬株式会社 | 抗癌剤 |
| US5637688A (en) * | 1994-12-13 | 1997-06-10 | Eli Lilly And Company | Process for preparing 1-(2'-deoxy-2'-difluoro-d-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride |
| DE69635114T2 (de) * | 1995-08-09 | 2006-03-02 | Banyu Pharmaceutical Co., Ltd. | Proteinfarnesyltransferase-inhibitoren in kombination mit hmgcoa-reduktase-inhibitoren zur behandlung von aids |
| TW350844B (en) * | 1995-12-22 | 1999-01-21 | Schering Corp | Tricyclic amides useful to inhibition of G-protein function and for treatment of proliferative diseases |
| EP0932399B1 (en) * | 1996-03-12 | 2006-01-04 | PG-TXL Company, L.P. | Water soluble paclitaxel prodrugs |
| JP2000507584A (ja) * | 1996-04-03 | 2000-06-20 | メルク エンド カンパニー インコーポレーテッド | ファルネシル―タンパク質転移酵素の阻害剤 |
| US20020034725A1 (en) * | 1996-04-15 | 2002-03-21 | W. Gillies Mckenna | Sensitization of cells to radiation and and chemotherapy |
| CA2251955A1 (en) * | 1996-04-18 | 1997-10-23 | Nancy E. Kohl | A method of treating cancer |
| JP2000508335A (ja) * | 1996-05-30 | 2000-07-04 | メルク エンド カンパニー インコーポレーテッド | 癌の治療方法 |
| US6337992B1 (en) * | 1997-01-29 | 2002-01-08 | Philips Medical Systems Technologies Ltd. | Predictive bolus tracking |
| CA2282683A1 (en) * | 1997-02-18 | 1998-08-20 | Canji, Inc. | Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms |
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1998
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- 1998-12-21 AT AT98963829T patent/ATE317697T1/de not_active IP Right Cessation
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- 1998-12-21 EP EP98963829A patent/EP1041985B1/en not_active Expired - Lifetime
- 1998-12-21 KR KR1020007006938A patent/KR100700907B1/ko not_active Expired - Fee Related
- 1998-12-21 WO PCT/US1998/026224 patent/WO1999032114A1/en not_active Ceased
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- 1998-12-21 PE PE1998001263A patent/PE20000042A1/es not_active Application Discontinuation
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- 1998-12-21 CN CN98813742A patent/CN1129431C/zh not_active Expired - Fee Related
- 1998-12-21 SK SK898-2000A patent/SK285584B6/sk not_active IP Right Cessation
- 1998-12-21 DE DE69833509T patent/DE69833509T2/de not_active Expired - Lifetime
- 1998-12-21 TW TW087121355A patent/TW581763B/zh not_active IP Right Cessation
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2000
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2007
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20101221 |