SK284688B6 - Spôsob zlepšenia ochrany membrány a potlačenia hemolýzy počas skladovania trombocytov a ich dôslednej sterilizácie a uzavretý kontajner s ich obsahom - Google Patents

Spôsob zlepšenia ochrany membrány a potlačenia hemolýzy počas skladovania trombocytov a ich dôslednej sterilizácie a uzavretý kontajner s ich obsahom Download PDF

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Publication number
SK284688B6
SK284688B6 SK1427-99A SK142799A SK284688B6 SK 284688 B6 SK284688 B6 SK 284688B6 SK 142799 A SK142799 A SK 142799A SK 284688 B6 SK284688 B6 SK 284688B6
Authority
SK
Slovakia
Prior art keywords
carnitine
alkanoyl
concentrated platelets
mixtures
rbc
Prior art date
Application number
SK1427-99A
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English (en)
Slovak (sk)
Other versions
SK142799A3 (en
Inventor
Secondo Dottori
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of SK142799A3 publication Critical patent/SK142799A3/sk
Publication of SK284688B6 publication Critical patent/SK284688B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0047—Ultraviolet radiation
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/22—Blood or products thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Packages (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
SK1427-99A 1997-04-16 1998-04-15 Spôsob zlepšenia ochrany membrány a potlačenia hemolýzy počas skladovania trombocytov a ich dôslednej sterilizácie a uzavretý kontajner s ich obsahom SK284688B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/840,765 US6482585B2 (en) 1997-04-16 1997-04-16 Storage and maintenance of blood products including red blood cells and platelets
PCT/IT1998/000086 WO1998046073A1 (en) 1997-04-16 1998-04-15 Improved storage and maintenance of blood products

Publications (2)

Publication Number Publication Date
SK142799A3 SK142799A3 (en) 2000-05-16
SK284688B6 true SK284688B6 (sk) 2005-09-08

Family

ID=25283169

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1427-99A SK284688B6 (sk) 1997-04-16 1998-04-15 Spôsob zlepšenia ochrany membrány a potlačenia hemolýzy počas skladovania trombocytov a ich dôslednej sterilizácie a uzavretý kontajner s ich obsahom

Country Status (21)

Country Link
US (2) US6482585B2 (xx)
EP (1) EP0975214B1 (xx)
JP (1) JP4467649B2 (xx)
KR (1) KR100508408B1 (xx)
CN (2) CN1698430A (xx)
AT (1) ATE257326T1 (xx)
AU (1) AU739842B2 (xx)
BR (1) BR9808911B1 (xx)
CA (1) CA2286721A1 (xx)
CZ (1) CZ298671B6 (xx)
DE (1) DE69821002T2 (xx)
DK (1) DK0975214T3 (xx)
ES (1) ES2212288T3 (xx)
HK (1) HK1025477A1 (xx)
HU (1) HUP0001936A3 (xx)
IL (1) IL132271A (xx)
NZ (1) NZ500534A (xx)
PL (1) PL192684B1 (xx)
PT (1) PT975214E (xx)
SK (1) SK284688B6 (xx)
WO (1) WO1998046073A1 (xx)

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US6482585B2 (en) * 1997-04-16 2002-11-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
US6403124B1 (en) * 1997-04-16 2002-06-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
SK288072B6 (sk) * 1999-10-11 2013-05-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
WO2005032251A1 (en) * 2003-10-09 2005-04-14 I.M.T. Interface Multigrad Technology Ltd. Method for freezing, thawing and transplantation of viable cartilage
US7935478B2 (en) * 2004-02-02 2011-05-03 Core Dynamics Limited Biological material and methods and solutions for preservation thereof
EP1711214A1 (en) * 2004-02-02 2006-10-18 Interface Multigrad Technology (IMT) Ltd. Device for directional cooling of biological matter
JP5096148B2 (ja) * 2004-06-07 2012-12-12 コア・ダイナミクス・リミテッド 生物学的試料の殺菌方法
EP1778007A1 (en) * 2004-08-12 2007-05-02 I.M.T. Interface Multigrad Technology Ltd. Method and apparatus for freezing or thawing of a biological material
WO2006090372A2 (en) * 2005-02-22 2006-08-31 I.M.T. Interface Multigrad Technology Ltd. Preserved viable cartilage, method for its preservation, and system and devices used therefor
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
US8198085B2 (en) * 2005-08-03 2012-06-12 Core Dynamics Limited Somatic cells for use in cell therapy
US7462485B2 (en) * 2005-10-07 2008-12-09 Glaser Lawrence F Modified erythrocytes and uses thereof
US8835104B2 (en) 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
US20090202978A1 (en) * 2008-02-13 2009-08-13 Ginadi Shaham Method and apparatus for freezing of a biological material
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
NZ599890A (en) 2009-10-12 2014-03-28 Univ Pittsburgh Oxygen depletion devices and methods for removing oxygen from red blood cells
JP6199557B2 (ja) 2009-10-12 2017-09-20 ニュー ヘルス サイエンシーズ、インク．Ｎｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 酸素及び二酸化炭素の減損能力をもつ血液保存袋システム及び減損装置
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
EP2490751B1 (en) 2009-10-23 2016-11-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
EP4091645A1 (en) 2010-08-25 2022-11-23 Hemanext Inc. Method for enhancing red blood cell quality and survival during storage
JP5859558B2 (ja) * 2010-11-05 2016-02-10 ニュー・ヘルス・サイエンシーズ・インコーポレイテッドＮｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 赤血球の照射及び嫌気性保存
WO2012075041A2 (en) 2010-11-29 2012-06-07 New York Blood Center, Inc. Method of blood pooling and storage
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
JP2014518547A (ja) 2011-04-07 2014-07-31 フェンウォール、インコーポレイテッド 削減された残存血漿容積を有する血小板濃縮物を提供するための自動化方法とシステムおよびそのような血小板濃縮物のための貯蔵媒体
EP2729000B1 (en) * 2011-07-05 2022-12-14 Hemanext Inc. A method for extended storage of red blood cells
EP4074395B1 (en) 2011-08-10 2024-01-24 Hemanext Inc. Integrated leukocyte, oxygen and/or co2 depletion, and plasma separation filter device
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CN107847395B (zh) 2015-04-23 2021-10-15 新健康科学股份有限公司 厌氧血液储存容器
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Also Published As

Publication number Publication date
WO1998046073A1 (en) 1998-10-22
PT975214E (pt) 2004-05-31
CN1252687A (zh) 2000-05-10
KR100508408B1 (ko) 2005-08-17
IL132271A (en) 2005-12-18
KR20010006464A (ko) 2001-01-26
CZ298671B6 (cs) 2007-12-19
US20030022228A1 (en) 2003-01-30
CA2286721A1 (en) 1998-10-22
DK0975214T3 (da) 2004-05-10
US6482585B2 (en) 2002-11-19
US6960428B2 (en) 2005-11-01
PL192684B1 (pl) 2006-11-30
BR9808911B1 (pt) 2010-09-21
PL336294A1 (en) 2000-06-19
JP4467649B2 (ja) 2010-05-26
AU739842B2 (en) 2001-10-18
JP2001523225A (ja) 2001-11-20
SK142799A3 (en) 2000-05-16
HUP0001936A3 (en) 2001-03-28
DE69821002D1 (de) 2004-02-12
ES2212288T3 (es) 2004-07-16
BR9808911A (pt) 2000-08-01
HUP0001936A2 (hu) 2000-10-28
CN1698430A (zh) 2005-11-23
HK1025477A1 (en) 2000-11-17
IL132271A0 (en) 2001-03-19
NZ500534A (en) 2001-05-25
DE69821002T2 (de) 2004-07-08
CZ368199A3 (cs) 2000-04-12
EP0975214A1 (en) 2000-02-02
AU7078198A (en) 1998-11-11
EP0975214B1 (en) 2004-01-07
ATE257326T1 (de) 2004-01-15
US20010049089A1 (en) 2001-12-06

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Effective date: 20130415