SK284247B6 - Lipozómový prípravok 6,9- bis[(2-aminoetyl)amino]benzo[g]izochinolín-5,10-dión dimaleátu a jeho použitie - Google Patents

Lipozómový prípravok 6,9- bis[(2-aminoetyl)amino]benzo[g]izochinolín-5,10-dión dimaleátu a jeho použitie Download PDF

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Publication number
SK284247B6
SK284247B6 SK538-2002A SK5382002A SK284247B6 SK 284247 B6 SK284247 B6 SK 284247B6 SK 5382002 A SK5382002 A SK 5382002A SK 284247 B6 SK284247 B6 SK 284247B6
Authority
SK
Slovakia
Prior art keywords
liposome
bbr
phosphatidylcholine
pho
acid
Prior art date
Application number
SK538-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK5382002A3 (en
Inventor
Carlo Bugatti
Original Assignee
Novuspharma S. P. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novuspharma S. P. A. filed Critical Novuspharma S. P. A.
Publication of SK5382002A3 publication Critical patent/SK5382002A3/sk
Publication of SK284247B6 publication Critical patent/SK284247B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK538-2002A 1999-10-22 2000-10-19 Lipozómový prípravok 6,9- bis[(2-aminoetyl)amino]benzo[g]izochinolín-5,10-dión dimaleátu a jeho použitie SK284247B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI002219A IT1315253B1 (it) 1999-10-22 1999-10-22 Preparazione liposomiale di 6,9-bis-(2-amminoetil)ammino|benzog|isochinolin-5,10-dione dimaleato
PCT/EP2000/010303 WO2001028521A2 (en) 1999-10-22 2000-10-19 Liposome formulation of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate

Publications (2)

Publication Number Publication Date
SK5382002A3 SK5382002A3 (en) 2002-09-10
SK284247B6 true SK284247B6 (sk) 2004-12-01

Family

ID=11383836

Family Applications (1)

Application Number Title Priority Date Filing Date
SK538-2002A SK284247B6 (sk) 1999-10-22 2000-10-19 Lipozómový prípravok 6,9- bis[(2-aminoetyl)amino]benzo[g]izochinolín-5,10-dión dimaleátu a jeho použitie

Country Status (23)

Country Link
US (1) US7449197B2 (ja)
EP (1) EP1221940B1 (ja)
JP (1) JP2003512313A (ja)
KR (1) KR20020063880A (ja)
CN (1) CN1164261C (ja)
AT (1) ATE335468T1 (ja)
AU (1) AU772339B2 (ja)
BR (1) BR0014881A (ja)
CA (1) CA2386143A1 (ja)
CZ (1) CZ20021388A3 (ja)
DE (1) DE60029979T2 (ja)
EA (1) EA004477B1 (ja)
ES (1) ES2269200T3 (ja)
HU (1) HUP0203473A3 (ja)
IL (2) IL149212A0 (ja)
IT (1) IT1315253B1 (ja)
MX (1) MXPA02003939A (ja)
NO (1) NO20021867L (ja)
NZ (1) NZ518005A (ja)
PL (1) PL197412B1 (ja)
SK (1) SK284247B6 (ja)
WO (1) WO2001028521A2 (ja)
ZA (1) ZA200203128B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU769569B2 (en) * 1998-12-18 2004-01-29 Alza Corporation Method of administering a compound to multi-drug resistant cells
ITMI20021040A1 (it) * 2002-05-16 2003-11-17 Novuspharma Spa Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
CN1305881C (zh) * 2004-08-13 2007-03-21 河南工业大学 磷脂酰胆碱的制备方法
CN103479578B (zh) * 2012-06-14 2016-08-03 沈阳药科大学 一种马来酸匹杉琼的脂质体制剂及其制备工艺
CN105596295B (zh) * 2016-01-25 2018-03-16 北京博恩特药业有限公司 马来酸匹杉琼脂质体及其制备方法
CN105997896B (zh) * 2016-05-28 2019-07-05 长沙秋点兵信息科技有限公司 治疗非霍奇金淋巴瘤的注射用冻干粉及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797285A (en) * 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
JPS6442418A (en) * 1985-12-06 1989-02-14 Yissum Res Dev Co Liposome/anthraquinone drug composition and therapy therewith
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
ES2072223B1 (es) * 1993-11-25 1996-03-16 Lipotec Sa Liposomas encapsulando doxorubicina.
WO1995024201A1 (fr) * 1994-03-11 1995-09-14 Yoshitomi Pharmaceutical Industries, Ltd. Preparation de liposomes
US5506232A (en) * 1994-03-28 1996-04-09 Boehringer Mannheim Italia S.P.A. 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and its dimaleate salt
US5587382A (en) * 1994-03-28 1996-12-24 Boehringer Mannheim Italia, Spa 6,9-bis[(2-aminoethyl) amino]benzo [g]isoquinoline-5,10- dione dimaleate; an aza-anthracenedione with reduced cardiotoxicity
JP2001514209A (ja) * 1997-09-04 2001-09-11 バイオゾーン ラボラトリーズ，インコーポレイテッド 経口リポソーム送達系

Also Published As

Publication number Publication date
MXPA02003939A (es) 2004-06-25
KR20020063880A (ko) 2002-08-05
AU772339B2 (en) 2004-04-22
BR0014881A (pt) 2002-06-11
ATE335468T1 (de) 2006-09-15
US20060078607A1 (en) 2006-04-13
WO2001028521A3 (en) 2002-04-25
IT1315253B1 (it) 2003-02-03
ES2269200T3 (es) 2007-04-01
SK5382002A3 (en) 2002-09-10
HUP0203473A3 (en) 2003-12-29
AU1514601A (en) 2001-04-30
ITMI992219A1 (it) 2001-04-22
CN1382039A (zh) 2002-11-27
WO2001028521A2 (en) 2001-04-26
NO20021867D0 (no) 2002-04-19
EA200200389A1 (ru) 2002-08-29
DE60029979T2 (de) 2007-02-22
IL149212A (en) 2006-12-10
PL197412B1 (pl) 2008-03-31
CZ20021388A3 (cs) 2002-08-14
EA004477B1 (ru) 2004-04-29
PL354610A1 (en) 2004-02-09
EP1221940A2 (en) 2002-07-17
DE60029979D1 (de) 2006-09-21
NO20021867L (no) 2002-04-19
ZA200203128B (en) 2003-06-05
JP2003512313A (ja) 2003-04-02
EP1221940B1 (en) 2006-08-09
CA2386143A1 (en) 2001-04-26
HUP0203473A2 (hu) 2003-02-28
US7449197B2 (en) 2008-11-11
IL149212A0 (en) 2002-11-10
NZ518005A (en) 2003-10-31
CN1164261C (zh) 2004-09-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20091019