PL354610A1 - Liposome formulation of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate - Google Patents

Liposome formulation of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate

Info

Publication number
PL354610A1
PL354610A1 PL00354610A PL35461000A PL354610A1 PL 354610 A1 PL354610 A1 PL 354610A1 PL 00354610 A PL00354610 A PL 00354610A PL 35461000 A PL35461000 A PL 35461000A PL 354610 A1 PL354610 A1 PL 354610A1
Authority
PL
Poland
Prior art keywords
isoquinoline
aminoethyl
benzo
bis
amino
Prior art date
Application number
PL00354610A
Other languages
Polish (pl)
Other versions
PL197412B1 (en
Inventor
Carlo Bugatti
Original Assignee
Novuspharma S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novuspharma S.P.A. filed Critical Novuspharma S.P.A.
Publication of PL354610A1 publication Critical patent/PL354610A1/en
Publication of PL197412B1 publication Critical patent/PL197412B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A liposome pharmaceutical formulation of the compound of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate, the method for the preparation and the use thereof.
PL354610A 1999-10-22 2000-10-19 Liposome formulation of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate PL197412B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI002219A IT1315253B1 (en) 1999-10-22 1999-10-22 LIPOSOMIAL PREPARATION OF 6,9-BIS- (2-AMINOXYL) AMINO | BENZOG | ISOCHINOLIN-5,10-DIONE DIMALEATO
PCT/EP2000/010303 WO2001028521A2 (en) 1999-10-22 2000-10-19 Liposome formulation of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate

Publications (2)

Publication Number Publication Date
PL354610A1 true PL354610A1 (en) 2004-02-09
PL197412B1 PL197412B1 (en) 2008-03-31

Family

ID=11383836

Family Applications (1)

Application Number Title Priority Date Filing Date
PL354610A PL197412B1 (en) 1999-10-22 2000-10-19 Liposome formulation of 6,9-bis-[(2-aminoethyl)-amino]benzo[g]isoquinoline-5,10-dione dimaleate

Country Status (23)

Country Link
US (1) US7449197B2 (en)
EP (1) EP1221940B1 (en)
JP (1) JP2003512313A (en)
KR (1) KR20020063880A (en)
CN (1) CN1164261C (en)
AT (1) ATE335468T1 (en)
AU (1) AU772339B2 (en)
BR (1) BR0014881A (en)
CA (1) CA2386143A1 (en)
CZ (1) CZ20021388A3 (en)
DE (1) DE60029979T2 (en)
EA (1) EA004477B1 (en)
ES (1) ES2269200T3 (en)
HU (1) HUP0203473A3 (en)
IL (2) IL149212A0 (en)
IT (1) IT1315253B1 (en)
MX (1) MXPA02003939A (en)
NO (1) NO20021867L (en)
NZ (1) NZ518005A (en)
PL (1) PL197412B1 (en)
SK (1) SK284247B6 (en)
WO (1) WO2001028521A2 (en)
ZA (1) ZA200203128B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2353593A1 (en) * 1998-12-18 2000-06-22 Hadasit Medical Research Services & Development Ltd. Method of administering a compound to multi-drug resistant cells
ITMI20021040A1 (en) 2002-05-16 2003-11-17 Novuspharma Spa INJECTABLE PHARMACEUTICAL COMPOSITIONS OF AN ANTHROCENEDIONAL DERIVATIVE WITH ANTI-TUMOR ACTIVITY
CN1305881C (en) * 2004-08-13 2007-03-21 河南工业大学 Method for preparing lecithin in high purity
CN103479578B (en) * 2012-06-14 2016-08-03 沈阳药科大学 The Liposomal formulation of a kind of maleic acid Pixantrone and preparation technology thereof
CN105596295B (en) * 2016-01-25 2018-03-16 北京博恩特药业有限公司 Maleic acid Pixantrone liposome and preparation method thereof
CN105997896B (en) * 2016-05-28 2019-07-05 长沙秋点兵信息科技有限公司 The injection freeze-dried powder and preparation method thereof for treating non-Hodgkin lymphoma

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797285A (en) * 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
JPS6442418A (en) * 1985-12-06 1989-02-14 Yissum Res Dev Co Liposome/anthraquinone drug composition and therapy therewith
MX9203808A (en) * 1987-03-05 1992-07-01 Liposome Co Inc HIGH DRUG CONTENT FORMULATIONS: LIPID, FROM LIPOSOMIC-ANTINEOPLASTIC AGENTS.
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
ES2072223B1 (en) * 1993-11-25 1996-03-16 Lipotec Sa LIPOSOMES ENCAPSULATING DOXORUBICIN.
CA2184834A1 (en) * 1994-03-11 1995-09-14 Yoshiyuki Mori Liposome preparation
US5587382A (en) * 1994-03-28 1996-12-24 Boehringer Mannheim Italia, Spa 6,9-bis[(2-aminoethyl) amino]benzo [g]isoquinoline-5,10- dione dimaleate; an aza-anthracenedione with reduced cardiotoxicity
US5506232A (en) * 1994-03-28 1996-04-09 Boehringer Mannheim Italia S.P.A. 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and its dimaleate salt
WO1999011242A1 (en) * 1997-09-04 1999-03-11 Biozone Laboratories, Inc. Oral liposomal delivery system

Also Published As

Publication number Publication date
NZ518005A (en) 2003-10-31
PL197412B1 (en) 2008-03-31
ITMI992219A1 (en) 2001-04-22
IT1315253B1 (en) 2003-02-03
WO2001028521A3 (en) 2002-04-25
CZ20021388A3 (en) 2002-08-14
DE60029979T2 (en) 2007-02-22
US20060078607A1 (en) 2006-04-13
EA200200389A1 (en) 2002-08-29
HUP0203473A2 (en) 2003-02-28
SK284247B6 (en) 2004-12-01
CA2386143A1 (en) 2001-04-26
BR0014881A (en) 2002-06-11
EP1221940B1 (en) 2006-08-09
CN1164261C (en) 2004-09-01
ZA200203128B (en) 2003-06-05
EP1221940A2 (en) 2002-07-17
MXPA02003939A (en) 2004-06-25
NO20021867D0 (en) 2002-04-19
SK5382002A3 (en) 2002-09-10
KR20020063880A (en) 2002-08-05
JP2003512313A (en) 2003-04-02
IL149212A0 (en) 2002-11-10
IL149212A (en) 2006-12-10
ATE335468T1 (en) 2006-09-15
US7449197B2 (en) 2008-11-11
DE60029979D1 (en) 2006-09-21
EA004477B1 (en) 2004-04-29
AU772339B2 (en) 2004-04-22
AU1514601A (en) 2001-04-30
CN1382039A (en) 2002-11-27
HUP0203473A3 (en) 2003-12-29
WO2001028521A2 (en) 2001-04-26
NO20021867L (en) 2002-04-19
ES2269200T3 (en) 2007-04-01

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20091019