AU6308900A - Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance - Google Patents

Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance

Info

Publication number
AU6308900A
AU6308900A AU63089/00A AU6308900A AU6308900A AU 6308900 A AU6308900 A AU 6308900A AU 63089/00 A AU63089/00 A AU 63089/00A AU 6308900 A AU6308900 A AU 6308900A AU 6308900 A AU6308900 A AU 6308900A
Authority
AU
Australia
Prior art keywords
preparation
pharmaceutical compositions
same
active substance
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU63089/00A
Inventor
Laszlo Balazs
Jozsef Barkoczy
Andras Bilkei-Gorzo
Imre Doman
Gabor Dornyei
Andras Egyed
Istvan Gacsalyi
Zoltan Greff
Maria Incze
Peter Kotay Nagy
Gyorgy Levay
Laszlo Poszavacz
Judit Raczne Barnogel
Zoltan Ratkai
Peter Seres
Gyula Simig
Csaba Szantay
Karoly Tihanyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9902590A external-priority patent/HUP9902590A3/en
Priority claimed from HU9902591A external-priority patent/HUP9902591A3/en
Priority claimed from HU9902592A external-priority patent/HUP9902592A3/en
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of AU6308900A publication Critical patent/AU6308900A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
AU63089/00A 1999-07-29 2000-07-28 Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance Abandoned AU6308900A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
HU9902590A HUP9902590A3 (en) 1999-07-29 1999-07-29 3,4-dihydro isoquinolinium derivatives, pharmaceutical compositions containing them and process for producing them
HU9902591 1999-07-29
HU9902592 1999-07-29
HU9902590 1999-07-29
HU9902591A HUP9902591A3 (en) 1999-07-29 1999-07-29 3,4-dihydro isoquinolinium derivatives, pharmaceutical compositions containing such active ingredients and process for producing them
HU9902592A HUP9902592A3 (en) 1999-07-29 1999-07-29 Isoquinoline derivatives, pharmaceutical compositions containing such active ingredients and process for producing them
PCT/HU2000/000087 WO2001009101A1 (en) 1999-07-29 2000-07-28 Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance

Publications (1)

Publication Number Publication Date
AU6308900A true AU6308900A (en) 2001-02-19

Family

ID=89998920

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63089/00A Abandoned AU6308900A (en) 1999-07-29 2000-07-28 Isoquinoline derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance

Country Status (7)

Country Link
EP (1) EP1200410A1 (en)
JP (1) JP2003506358A (en)
AU (1) AU6308900A (en)
CZ (1) CZ2002342A3 (en)
PL (1) PL352041A1 (en)
SK (1) SK1212002A3 (en)
WO (1) WO2001009101A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03000966A (en) * 2002-02-28 2003-09-04 Pfizer Prod Inc Antidiabetic agents.
AR077223A1 (en) 2009-06-26 2011-08-10 Sanofi Aventis SMOKE SALTS OF AN H3 HISTAMINE RECEIVER ANTAGONIST
CA3107453A1 (en) * 2018-07-23 2020-01-30 Ohio State Innovation Foundation Derivatives of papaverine that are effective hypoxic tumor radiosensitizers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH410007A (en) * 1961-04-21 1966-03-31 Hoffmann La Roche Process for the preparation of tertiary amines
DE1902402A1 (en) * 1968-05-21 1969-11-27 Dresden Arzneimittel 1-subst 6 7-dimethoxy-isoquinolines inhibitors of
DE1902559A1 (en) * 1968-07-05 1970-03-26 Dresden Arzneimittel 1-substd-3 4-dihydro-6 7-dimethoxy-isoquinolines
GB1181959A (en) * 1969-01-30 1970-02-18 Dresden Arzneimittel 6,7-Dimethoxy-3,4-Dihydroisoquinoline Derivatives
GB8419658D0 (en) * 1984-08-01 1984-09-05 Wellcome Found Nitrogen containing heterocyclic compounds
HUT71407A (en) * 1994-05-03 1995-11-28 Egyt Gyogyszervegyeszeti Gyar Heterocyclic compounds, pharmaceutical compositions containing them, and process for producing the active components
EP0787493A1 (en) * 1996-02-03 1997-08-06 F. Hoffmann-La Roche Ag Tetrahydroisoquinoline derivatives

Also Published As

Publication number Publication date
PL352041A1 (en) 2003-07-28
WO2001009101A1 (en) 2001-02-08
SK1212002A3 (en) 2002-11-06
JP2003506358A (en) 2003-02-18
EP1200410A1 (en) 2002-05-02
CZ2002342A3 (en) 2002-06-12

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase