SK283990B6 - Spôsob prípravy 1-substituovaných 4-kyano-1,2,3-triazolov, 4-kyano-1-(2,6-difluórbenzyl)-1H-1,2,3-triazol - Google Patents

Spôsob prípravy 1-substituovaných 4-kyano-1,2,3-triazolov, 4-kyano-1-(2,6-difluórbenzyl)-1H-1,2,3-triazol Download PDF

Info

Publication number
SK283990B6
SK283990B6 SK26-99A SK2699A SK283990B6 SK 283990 B6 SK283990 B6 SK 283990B6 SK 2699 A SK2699 A SK 2699A SK 283990 B6 SK283990 B6 SK 283990B6
Authority
SK
Slovakia
Prior art keywords
formula
phenyl
lower alkyl
group
difluorobenzyl
Prior art date
Application number
SK26-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK2699A3 (en
Inventor
Robert Portmann
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK2699A3 publication Critical patent/SK2699A3/sk
Publication of SK283990B6 publication Critical patent/SK283990B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK26-99A 1996-07-11 1997-07-10 Spôsob prípravy 1-substituovaných 4-kyano-1,2,3-triazolov, 4-kyano-1-(2,6-difluórbenzyl)-1H-1,2,3-triazol SK283990B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH174796 1996-07-11
PCT/EP1997/003671 WO1998002423A1 (en) 1996-07-11 1997-07-10 Process for preparing 1-substituted 4-cyano-1,2,3-triazoles

Publications (2)

Publication Number Publication Date
SK2699A3 SK2699A3 (en) 1999-06-11
SK283990B6 true SK283990B6 (sk) 2004-07-07

Family

ID=4217633

Family Applications (1)

Application Number Title Priority Date Filing Date
SK26-99A SK283990B6 (sk) 1996-07-11 1997-07-10 Spôsob prípravy 1-substituovaných 4-kyano-1,2,3-triazolov, 4-kyano-1-(2,6-difluórbenzyl)-1H-1,2,3-triazol

Country Status (24)

Country Link
US (2) US6156907A (ja)
EP (1) EP0918758B1 (ja)
JP (1) JP3537147B2 (ja)
KR (1) KR100481137B1 (ja)
CN (1) CN1083436C (ja)
AT (1) ATE216990T1 (ja)
AU (1) AU719148B2 (ja)
BR (1) BR9710252B1 (ja)
CA (1) CA2260065C (ja)
CZ (1) CZ294775B6 (ja)
DE (1) DE69712342T2 (ja)
DK (1) DK0918758T3 (ja)
ES (1) ES2176758T3 (ja)
HU (1) HU226425B1 (ja)
IL (1) IL127665A (ja)
NO (1) NO326347B1 (ja)
NZ (1) NZ333505A (ja)
PL (1) PL189232B1 (ja)
PT (1) PT918758E (ja)
RU (1) RU2177942C2 (ja)
SI (1) SI0918758T1 (ja)
SK (1) SK283990B6 (ja)
TR (1) TR199900017T2 (ja)
WO (1) WO1998002423A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW403740B (en) * 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
CN100335467C (zh) * 2004-06-04 2007-09-05 中国科学院上海有机化学研究所 一锅法区域选择性合成5－碘代－1，4－二取代－1，2，3－三氮唑化合物
US8183269B2 (en) 2008-10-13 2012-05-22 Cipla Limited Process for the preparation of rufinamide
EP2378879A4 (en) * 2008-12-16 2012-06-06 Merck Sharp & Dohme TRIAZONE DERIVATIVES FOR THE TREATMENT OF MORBUS ALZHEIMER
CN101768124B (zh) * 2008-12-30 2012-01-04 北京本草天源药物研究院 一种药物晶体及其制备方法和用途
EP2640711B1 (en) * 2010-08-25 2015-10-14 Davuluri, Ramamohan Rao Improved process for the preparation of rufinamide
WO2012032540A1 (en) 2010-09-06 2012-03-15 Indoco Remedies Limited Process for preparation of fluorinated triazole compound
CN102219752B (zh) * 2011-04-21 2013-04-10 华润赛科药业有限责任公司 一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的晶型d
WO2014072992A1 (en) 2012-11-12 2014-05-15 Aarti Industries Limited A process for preparing triazole compounds
RU2591206C1 (ru) * 2015-04-14 2016-07-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский химико-технологический университет имени Д.И. Менделеева (РХТУ им. Д.И. Менделеева)" Замещенные 1-(1-трет-бутил-1н-имидазол-4-ил)-1н-1,2,3-триазолы, способ их получения и фунгицидная композиция на их основе

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS596305B2 (ja) * 1980-03-11 1984-02-10 工業技術院長 １，２，３−トリアゾ−ル誘導体の製造方法
US4789680A (en) * 1982-12-23 1988-12-06 Ciba-Geigy Corporation Aralkyltriazole compounds
FI93544C (fi) * 1985-04-18 1995-04-25 Ciba Geigy Ag Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi

Also Published As

Publication number Publication date
BR9710252A (pt) 1999-08-10
DK0918758T3 (da) 2002-08-19
IL127665A (en) 2004-03-28
DE69712342D1 (de) 2002-06-06
KR100481137B1 (ko) 2005-04-08
PT918758E (pt) 2002-09-30
ES2176758T3 (es) 2002-12-01
JP2000507602A (ja) 2000-06-20
EP0918758A1 (en) 1999-06-02
NZ333505A (en) 2000-06-23
AU3622097A (en) 1998-02-09
BR9710252B1 (pt) 2010-06-29
WO1998002423A1 (en) 1998-01-22
EP0918758B1 (en) 2002-05-02
PL330914A1 (en) 1999-06-07
CZ294775B6 (cs) 2005-03-16
DE69712342T2 (de) 2002-11-14
NO990056L (no) 1999-01-07
HUP9902842A3 (en) 2000-04-28
CN1225087A (zh) 1999-08-04
US6277999B1 (en) 2001-08-21
PL189232B1 (pl) 2005-07-29
CA2260065C (en) 2006-10-17
NO990056D0 (no) 1999-01-07
SI0918758T1 (en) 2002-10-31
HUP9902842A2 (hu) 2000-02-28
NO326347B1 (no) 2008-11-17
JP3537147B2 (ja) 2004-06-14
AU719148B2 (en) 2000-05-04
CN1083436C (zh) 2002-04-24
IL127665A0 (en) 1999-10-28
US6156907A (en) 2000-12-05
RU2177942C2 (ru) 2002-01-10
SK2699A3 (en) 1999-06-11
HU226425B1 (en) 2008-12-29
ATE216990T1 (de) 2002-05-15
KR20000023595A (ko) 2000-04-25
CA2260065A1 (en) 1998-01-22
TR199900017T2 (xx) 1999-04-21
CZ4299A3 (cs) 1999-04-14

Similar Documents

Publication Publication Date Title
JP3292845B2 (ja) 新規なアリールエテニレン誘導体及びその製法
AU665238B2 (en) S-triazine derivative and remedy for estrogen-dependent diseases containing the same as active ingredient
SK2622002A3 (en) N-heterocyclic derivatives as nitric oxide synthase inhibitors and pharmaceutical compositions containing these compounds
NO841106L (no) Fremgangsmaate for fremstilling av kondenserte imidazolderivater
JPS6339875A (ja) ピリミジン誘導体
FR2542315A1 (fr) Nouveaux composes azoliques, leur preparation et leur utilisation comme antifongiques et fongicides
SK283990B6 (sk) Spôsob prípravy 1-substituovaných 4-kyano-1,2,3-triazolov, 4-kyano-1-(2,6-difluórbenzyl)-1H-1,2,3-triazol
HU194837B (en) Process for preparing triazole derivatives and fungicides comprising the same as active substance
US20050130989A1 (en) N-arylheteroaromatic products compositions containing them and use thereof
EP1678135B1 (en) Process for the preparation of n-amino substituted heterocyclic compounds
DE69208490T2 (de) 1,2,4-Oxadiazolderivate mit einer Monoamino-Oxidase-B-Enzymhemmenden Wirkung und Verfahren zu ihrer Herstellung
US4423046A (en) Antibacterial and antiprotozoal 1-methyl-5-nitro-2-(2-phenylvinyl)imidazoles
HU182740B (en) Process for producing 4-pyrimidon compounds of novel histamine h2-antagonistic activity
JP3207417B2 (ja) シクロアルキレンアゾール、その製造、これを有する製剤並びに医薬品の製造のためのその使用
HU191388B (en) Process for preparing new derivatives of aralkyl-triazoles and pharmaceutical compositions containing such compounds
RU2232761C2 (ru) Производные триазола амидного типа, фармацевтическая композиция на их основе и способ профилактики или лечения
US5635521A (en) Imidazolylmethyl-pyridines
EP0967210B1 (en) Process for preparing biologically active derivatives of 1,2,4-triazol and intermediaries useful in this process
NO126624B (ja)
US8198461B2 (en) Process for the preparation of 3-cyano-1,2,4-triazoles
EP0169164B1 (en) Imidazolonecarbonylarylimidazoles; method of manufacture, method of use and compositions useful thereof
Corral et al. Reactions of methyl 3‐hydroxythiophene‐2‐carboxylate. Part 4. Synthesis of methyl 5‐azolyl‐3‐hydroxythiophene‐2‐carboxylates
JPH0662578B2 (ja) １−置換５−アミノピラゾールの製法
JPH05194429A (ja) アゾール化合物、その製造法および用途

Legal Events

Date Code Title Description
MK4A Expiry of patent

Expiry date: 20170710