SK283850B6 - Aktín-rezistentné varianty humánnej DNázy I, ich príprava, použitie a farmaceutický prostriedok s ich obsahom - Google Patents

Aktín-rezistentné varianty humánnej DNázy I, ich príprava, použitie a farmaceutický prostriedok s ich obsahom Download PDF

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Publication number
SK283850B6
SK283850B6 SK1147-97A SK114797A SK283850B6 SK 283850 B6 SK283850 B6 SK 283850B6 SK 114797 A SK114797 A SK 114797A SK 283850 B6 SK283850 B6 SK 283850B6
Authority
SK
Slovakia
Prior art keywords
actin
variant
dna
dnase
amino acid
Prior art date
Application number
SK1147-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK114797A3 (en
Inventor
Robert A. Lazarus
Steven Shak
Jana S. Ulmer
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22248728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK283850(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of SK114797A3 publication Critical patent/SK114797A3/sk
Publication of SK283850B6 publication Critical patent/SK283850B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK1147-97A 1995-02-24 1995-02-24 Aktín-rezistentné varianty humánnej DNázy I, ich príprava, použitie a farmaceutický prostriedok s ich obsahom SK283850B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/002366 WO1996026278A1 (en) 1995-02-24 1995-02-24 HUMAN DNase I VARIANTS

Publications (2)

Publication Number Publication Date
SK114797A3 SK114797A3 (en) 1998-02-04
SK283850B6 true SK283850B6 (sk) 2004-03-02

Family

ID=22248728

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1147-97A SK283850B6 (sk) 1995-02-24 1995-02-24 Aktín-rezistentné varianty humánnej DNázy I, ich príprava, použitie a farmaceutický prostriedok s ich obsahom

Country Status (22)

Country Link
EP (1) EP0811068B1 (pt)
JP (1) JPH11505408A (pt)
AT (1) ATE230027T1 (pt)
AU (1) AU720635B2 (pt)
BG (1) BG64061B1 (pt)
BR (1) BR9510323A (pt)
CA (1) CA2210871C (pt)
CZ (1) CZ288633B6 (pt)
DE (1) DE69529235T2 (pt)
DK (1) DK0811068T3 (pt)
ES (1) ES2188653T3 (pt)
HU (1) HU223272B1 (pt)
MX (1) MX9706428A (pt)
NO (1) NO326612B1 (pt)
PL (1) PL180773B1 (pt)
PT (1) PT811068E (pt)
RU (1) RU2215787C2 (pt)
SI (1) SI9520153B (pt)
SK (1) SK283850B6 (pt)
UA (2) UA66749C2 (pt)
WO (1) WO1996026278A1 (pt)
ZA (1) ZA961419B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284191B6 (sk) * 1995-02-24 2004-10-05 Genentech, Inc. Aktín-rezistentný variant humánnej DNázy I
US6391607B1 (en) * 1996-06-14 2002-05-21 Genentech, Inc. Human DNase I hyperactive variants
EP1433842B1 (en) 2002-12-18 2011-01-05 Roche Diagnostics GmbH Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
ATE494367T1 (de) 2002-12-18 2011-01-15 Hoffmann La Roche Rekombinante desoxyribonuclease i aus rinder- pankreas mit hoher spezifischer aktivität
WO2013114371A1 (en) * 2012-02-01 2013-08-08 Protalix Ltd. Dry powder formulations of dnase i

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990007572A1 (en) * 1988-12-23 1990-07-12 Genentech, Inc. HUMAN DNase
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I

Also Published As

Publication number Publication date
PT811068E (pt) 2003-04-30
CZ288633B6 (cs) 2001-08-15
BG64061B1 (bg) 2003-11-28
SK114797A3 (en) 1998-02-04
MX9706428A (es) 1997-11-29
HUT77422A (hu) 1998-04-28
UA65523C2 (en) 2004-04-15
NO326612B1 (no) 2009-01-19
BR9510323A (pt) 1997-11-11
CZ267797A3 (cs) 1998-01-14
ATE230027T1 (de) 2003-01-15
DE69529235D1 (de) 2003-01-30
NO973876L (no) 1997-10-24
ZA961419B (en) 1997-08-22
EP0811068A1 (en) 1997-12-10
CA2210871A1 (en) 1996-08-29
HU223272B1 (hu) 2004-04-28
DE69529235T2 (de) 2003-09-04
PL321890A1 (en) 1997-12-22
AU1970395A (en) 1996-09-11
SI9520153B (sl) 2004-10-31
WO1996026278A1 (en) 1996-08-29
ES2188653T3 (es) 2003-07-01
EP0811068B1 (en) 2002-12-18
NO973876D0 (no) 1997-08-22
JPH11505408A (ja) 1999-05-21
UA66749C2 (en) 2004-06-15
SI9520153A (sl) 1998-06-30
BG101846A (en) 1998-07-31
PL180773B1 (pl) 2001-04-30
DK0811068T3 (da) 2003-03-10
RU2215787C2 (ru) 2003-11-10
CA2210871C (en) 2009-04-07
AU720635B2 (en) 2000-06-08

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Expiry date: 20150224