SK283039B6 - 3-Substituované 3,4,5,6,7,8-hexahydropyrido [4',3':4,5] tieno [2,3-d]-pyrimidínové deriváty a ich použitie - Google Patents

3-Substituované 3,4,5,6,7,8-hexahydropyrido [4',3':4,5] tieno [2,3-d]-pyrimidínové deriváty a ich použitie Download PDF

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Publication number
SK283039B6
SK283039B6 SK230-99A SK23099A SK283039B6 SK 283039 B6 SK283039 B6 SK 283039B6 SK 23099 A SK23099 A SK 23099A SK 283039 B6 SK283039 B6 SK 283039B6
Authority
SK
Slovakia
Prior art keywords
thieno
hexahydro
pyrimidin
pyrido
methyl
Prior art date
Application number
SK230-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK23099A3 (en
Inventor
Gerd Steiner
Wilfried Lubisch
Alfred Bach
Franz Emling
Karsten Wicke
Hans-J�Rgen Teschendorf
Berthold Behl
Frank Kerrrigan
Sharon Cheetham
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of SK23099A3 publication Critical patent/SK23099A3/sk
Publication of SK283039B6 publication Critical patent/SK283039B6/sk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK230-99A 1996-09-10 1997-08-22 3-Substituované 3,4,5,6,7,8-hexahydropyrido [4',3':4,5] tieno [2,3-d]-pyrimidínové deriváty a ich použitie SK283039B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19636769A DE19636769A1 (de) 1996-09-10 1996-09-10 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
PCT/EP1997/004593 WO1998011110A1 (de) 1996-09-10 1997-08-22 3-substituierte pyrido [4',3':4,5] thieno [2,3-d]pyrimidin-derivate, ihre herstellung und verwendung

Publications (2)

Publication Number Publication Date
SK23099A3 SK23099A3 (en) 1999-08-06
SK283039B6 true SK283039B6 (sk) 2003-02-04

Family

ID=7805168

Family Applications (1)

Application Number Title Priority Date Filing Date
SK230-99A SK283039B6 (sk) 1996-09-10 1997-08-22 3-Substituované 3,4,5,6,7,8-hexahydropyrido [4',3':4,5] tieno [2,3-d]-pyrimidínové deriváty a ich použitie

Country Status (32)

Country Link
US (1) US6222034B1 (no)
EP (1) EP0927184B1 (no)
JP (1) JP2001500138A (no)
KR (1) KR20000035987A (no)
CN (2) CN1230962A (no)
AR (1) AR009572A1 (no)
AT (1) ATE252587T1 (no)
AU (1) AU736678B2 (no)
BG (1) BG63602B1 (no)
BR (1) BR9711724A (no)
CA (1) CA2265509A1 (no)
CO (1) CO4900071A1 (no)
CZ (1) CZ288896B6 (no)
DE (2) DE19636769A1 (no)
DK (1) DK0927184T3 (no)
ES (1) ES2210570T3 (no)
HK (1) HK1043593A1 (no)
HR (1) HRP970484A2 (no)
HU (1) HUP9904107A3 (no)
ID (1) ID18260A (no)
IL (1) IL128142A0 (no)
NO (1) NO991132L (no)
NZ (1) NZ334350A (no)
PL (1) PL332144A1 (no)
PT (1) PT927184E (no)
RU (1) RU2198888C2 (no)
SK (1) SK283039B6 (no)
TR (1) TR199900503T2 (no)
TW (1) TW480264B (no)
UA (1) UA54449C2 (no)
WO (1) WO1998011110A1 (no)
ZA (1) ZA978081B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19724979A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724980A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19734444A1 (de) * 1997-08-08 1999-02-11 Basf Ag 3-Substituierte 3,4,5,7-Tetrahydro-pyrrolo(3',4':4,5) thieno (2,3-d) pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19900545A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
DE19900673A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen
FR2791980B1 (fr) * 1999-04-09 2001-07-06 Sod Conseils Rech Applic Pyrido-thieno-diazepines, leur procede de preparation, et les compositions pharmaceutiques les contenant
DE10031390A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
ES2291329T3 (es) * 2000-07-18 2008-03-01 Dainippon Sumitomo Pharma Co., Ltd. Inhibidores de la recaptacion de serotonina.
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
BRPI0408988A (pt) * 2003-03-31 2006-03-28 Predix Pharmaceuticals Holding composto de piperidinilamino-tieno[2,3-d]pirimidina
US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
WO2010065743A2 (en) * 2008-12-03 2010-06-10 Nanotherapeutics, Inc. Bicyclic compounds and methods of making and using same
RU2559626C9 (ru) * 2010-04-14 2016-05-27 Байер Интеллектуэль Проперти Гмбх Способ получения дитиин-тетракарбоксимидов

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE272086C (no) *
DE272079C (no) *
DE272088C (no) *
US3823151A (en) * 1968-08-02 1974-07-09 Ciba Geigy Corp 4,5,6,7-tetrahydrothieno(2,3-d)pyridines
DE1937459A1 (de) * 1968-08-02 1970-02-05 Ciba Geigy Neue Pyrimidinderivate und Verfahren zu ihrer Herstellung
JPS60146891A (ja) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd 〔2,3−d〕チエノピリミジン誘導体およびその塩
DE3752141T2 (de) * 1986-02-24 1998-03-26 Mitsui Petrochemical Ind Mittel zur behandlung von neuropathie
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4835157A (en) * 1988-03-15 1989-05-30 Ortho Pharmaceutical Corporation Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents

Also Published As

Publication number Publication date
CN1230962A (zh) 1999-10-06
NZ334350A (en) 2000-07-28
ID18260A (id) 1998-03-19
EP0927184B1 (de) 2003-10-22
TW480264B (en) 2002-03-21
PT927184E (pt) 2004-03-31
NO991132D0 (no) 1999-03-09
JP2001500138A (ja) 2001-01-09
AU4207197A (en) 1998-04-02
HK1043593A1 (zh) 2002-09-20
HUP9904107A2 (hu) 2000-05-28
AR009572A1 (es) 2000-04-26
DK0927184T3 (da) 2004-03-01
ATE252587T1 (de) 2003-11-15
IL128142A0 (en) 1999-11-30
US6222034B1 (en) 2001-04-24
CO4900071A1 (es) 2000-03-27
NO991132L (no) 1999-03-09
HRP970484A2 (en) 1998-10-31
DE59710902D1 (de) 2003-11-27
CN1332168A (zh) 2002-01-23
BG103122A (en) 1999-09-30
BG63602B1 (bg) 2002-06-28
TR199900503T2 (xx) 1999-07-21
ES2210570T3 (es) 2004-07-01
HUP9904107A3 (en) 2001-10-29
EP0927184A1 (de) 1999-07-07
CA2265509A1 (en) 1998-03-19
PL332144A1 (en) 1999-08-30
BR9711724A (pt) 1999-08-24
CZ288896B6 (cs) 2001-09-12
KR20000035987A (ko) 2000-06-26
CZ75999A3 (cs) 1999-06-16
ZA978081B (en) 1999-03-09
AU736678B2 (en) 2001-08-02
DE19636769A1 (de) 1998-03-12
UA54449C2 (uk) 2003-03-17
WO1998011110A1 (de) 1998-03-19
RU2198888C2 (ru) 2003-02-20
SK23099A3 (en) 1999-08-06

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