SK282545B6 - Kryštalické adičné soli cefému s kyselinami, spôsob ich výroby, ich použitie a liečivo s ich obsahom - Google Patents

Kryštalické adičné soli cefému s kyselinami, spôsob ich výroby, ich použitie a liečivo s ich obsahom Download PDF

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Publication number
SK282545B6
SK282545B6 SK1397-95A SK139795A SK282545B6 SK 282545 B6 SK282545 B6 SK 282545B6 SK 139795 A SK139795 A SK 139795A SK 282545 B6 SK282545 B6 SK 282545B6
Authority
SK
Slovakia
Prior art keywords
formula
acid
acids
compounds
anion
Prior art date
Application number
SK1397-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK139795A3 (en
Inventor
Rudolf Lattrell
Walter D�Rckheimer
Peter Schmid
Original Assignee
Aventis Pharma Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh
Publication of SK139795A3 publication Critical patent/SK139795A3/sk
Publication of SK282545B6 publication Critical patent/SK282545B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SK1397-95A 1994-11-10 1995-11-08 Kryštalické adičné soli cefému s kyselinami, spôsob ich výroby, ich použitie a liečivo s ich obsahom SK282545B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4440141A DE4440141A1 (de) 1994-11-10 1994-11-10 Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
SK139795A3 SK139795A3 (en) 1996-06-05
SK282545B6 true SK282545B6 (sk) 2002-10-08

Family

ID=6532953

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1397-95A SK282545B6 (sk) 1994-11-10 1995-11-08 Kryštalické adičné soli cefému s kyselinami, spôsob ich výroby, ich použitie a liečivo s ich obsahom

Country Status (28)

Country Link
US (1) US5747484A (fr)
EP (1) EP0711774B1 (fr)
JP (1) JP3920939B2 (fr)
KR (1) KR100449191B1 (fr)
CN (1) CN1066452C (fr)
AR (1) AR002246A1 (fr)
AT (1) ATE213248T1 (fr)
AU (1) AU707730B2 (fr)
BR (1) BR9505132A (fr)
CA (1) CA2162530C (fr)
CZ (1) CZ290936B6 (fr)
DE (2) DE4440141A1 (fr)
DK (1) DK0711774T3 (fr)
ES (1) ES2172549T3 (fr)
FI (1) FI120263B (fr)
HU (1) HU219475B (fr)
IL (1) IL115914A (fr)
MA (1) MA23709A1 (fr)
NO (1) NO311891B1 (fr)
NZ (1) NZ280424A (fr)
OA (1) OA10242A (fr)
PL (1) PL182806B1 (fr)
PT (1) PT711774E (fr)
RU (1) RU2161619C2 (fr)
SK (1) SK282545B6 (fr)
TR (1) TR199501392A2 (fr)
TW (1) TW422847B (fr)
ZA (1) ZA959510B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049130A2 (fr) * 1997-04-29 1998-11-05 The University Of New Mexico Acides hydroxynaphtoiques et derives de ces derniers
CA2501395C (fr) * 2002-10-25 2011-05-24 Akzo Nobel Nv Composition pharmaceutique a liberation prolongee
US20080318919A1 (en) * 2005-10-29 2008-12-25 Intervet International B.V. Cefquinome Compositions and Methods of Their Use
AR077320A1 (es) * 2009-07-20 2011-08-17 Intervet Int Bv Metodo para la preparacion de particulas de cefquinoma y formulaciones farmaceuticas que las comprenden.
EP2862569A1 (fr) 2011-09-09 2015-04-22 Cubist Pharmaceuticals, Inc. Procédés pour traiter des infections intrapulmonaires
EP2750706A4 (fr) * 2011-09-29 2015-04-15 Alere San Diego Inc Analogues d'acide 2-hydroxyhippurique et procédés pour leurs synthèses et utilisation
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
KR102226197B1 (ko) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
WO2015035376A2 (fr) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Traitement d'infections au moyen de ceftolozane/tazobactam chez des sujets ayant une fonction rénale altérée
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
KR100449191B1 (ko) 2006-01-12
AU707730B2 (en) 1999-07-15
PL182806B1 (pl) 2002-03-29
AU3772895A (en) 1996-05-16
CA2162530C (fr) 2007-07-31
OA10242A (fr) 1997-09-19
ES2172549T3 (es) 2002-10-01
CA2162530A1 (fr) 1996-05-11
AR002246A1 (es) 1998-03-11
BR9505132A (pt) 1997-09-09
FI955382A (fi) 1996-05-11
NO311891B1 (no) 2002-02-11
MA23709A1 (fr) 1996-07-01
DE59510048D1 (de) 2002-03-21
IL115914A (en) 2002-08-14
KR960017670A (ko) 1996-06-17
RU2161619C2 (ru) 2001-01-10
DK0711774T3 (da) 2002-04-22
TR199501392A2 (tr) 1996-07-21
EP0711774A1 (fr) 1996-05-15
HU219475B (hu) 2001-04-28
JP3920939B2 (ja) 2007-05-30
FI955382A0 (fi) 1995-11-08
NZ280424A (en) 1997-06-24
EP0711774B1 (fr) 2002-02-13
PT711774E (pt) 2002-07-31
HUT74163A (en) 1996-11-28
PL311326A1 (en) 1996-05-13
HU9503213D0 (en) 1996-01-29
CN1066452C (zh) 2001-05-30
JPH08208662A (ja) 1996-08-13
CZ293395A3 (en) 1996-05-15
ATE213248T1 (de) 2002-02-15
TW422847B (en) 2001-02-21
SK139795A3 (en) 1996-06-05
US5747484A (en) 1998-05-05
IL115914A0 (en) 1996-01-31
NO954511L (no) 1996-05-13
CZ290936B6 (cs) 2002-11-13
NO954511D0 (no) 1995-11-09
DE4440141A1 (de) 1996-05-15
CN1129220A (zh) 1996-08-21
ZA959510B (en) 1996-05-28
FI120263B (fi) 2009-08-31

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Legal Events

Date Code Title Description
MK4A Expiry of patent

Expiry date: 20151108