SK282441B6 - Polypeptid s aktivitou pľúcneho surfaktantu a farmaceutický prostriedok s jeho obsahom - Google Patents
Polypeptid s aktivitou pľúcneho surfaktantu a farmaceutický prostriedok s jeho obsahom Download PDFInfo
- Publication number
- SK282441B6 SK282441B6 SK1524-96A SK152496A SK282441B6 SK 282441 B6 SK282441 B6 SK 282441B6 SK 152496 A SK152496 A SK 152496A SK 282441 B6 SK282441 B6 SK 282441B6
- Authority
- SK
- Slovakia
- Prior art keywords
- phe
- leu
- polypeptide
- surfactant
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4418936A DE4418936A1 (de) | 1994-05-31 | 1994-05-31 | Polypeptid |
PCT/EP1995/002028 WO1995032992A1 (de) | 1994-05-31 | 1995-05-27 | Synthetische peptidanaloge des lungenoberflächenproteins sp-c |
Publications (2)
Publication Number | Publication Date |
---|---|
SK152496A3 SK152496A3 (en) | 1997-06-04 |
SK282441B6 true SK282441B6 (sk) | 2002-02-05 |
Family
ID=6519392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK1524-96A SK282441B6 (sk) | 1994-05-31 | 1995-05-27 | Polypeptid s aktivitou pľúcneho surfaktantu a farmaceutický prostriedok s jeho obsahom |
Country Status (29)
Country | Link |
---|---|
US (1) | US5874406A (pt) |
EP (1) | EP0764172B1 (pt) |
JP (1) | JP3359638B2 (pt) |
KR (1) | KR100355626B1 (pt) |
CN (1) | CN1130374C (pt) |
AT (1) | ATE275154T1 (pt) |
AU (1) | AU690280B2 (pt) |
BG (1) | BG63210B1 (pt) |
BR (1) | BR9507811B1 (pt) |
CA (1) | CA2191344C (pt) |
CY (1) | CY2552B1 (pt) |
CZ (1) | CZ286976B6 (pt) |
DE (2) | DE4418936A1 (pt) |
DK (1) | DK0764172T3 (pt) |
EE (1) | EE03775B1 (pt) |
ES (1) | ES2227548T3 (pt) |
FI (1) | FI118126B (pt) |
HK (1) | HK1000891A1 (pt) |
HU (1) | HU220191B (pt) |
NO (1) | NO317149B1 (pt) |
NZ (1) | NZ287447A (pt) |
PL (1) | PL181234B1 (pt) |
PT (1) | PT764172E (pt) |
RO (1) | RO118752B1 (pt) |
RU (1) | RU2145611C1 (pt) |
SI (1) | SI0764172T1 (pt) |
SK (1) | SK282441B6 (pt) |
UA (1) | UA35636C2 (pt) |
WO (1) | WO1995032992A1 (pt) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2322097A (en) * | 1996-03-27 | 1997-10-17 | Ortho Pharmaceutical Corporation | Lyophilized pulmonary surfactant peptide compositions |
DE19851119C2 (de) | 1998-11-06 | 2001-05-31 | Byk Gulden Lomberg Chem Fab | Behälter und Vorrichtung zur Blindung der Verabreichung von nicht festen pharmazeutischen Darreichungsformen bei der klinischen Prüfung |
IT1308180B1 (it) * | 1999-02-12 | 2001-12-07 | Chiesi Farma Spa | Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante |
WO2000076535A1 (en) * | 1999-06-11 | 2000-12-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c) |
CA2375214C (en) * | 1999-06-17 | 2012-01-17 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Surfactant protein c esters |
AU6083899A (en) | 1999-09-16 | 2001-04-17 | Aventis Behring Gmbh | Combination of c1-inh and lung surfactant for the treatment of respiratory disorders |
WO2001039573A2 (de) * | 1999-12-01 | 2001-06-07 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Verwendung von lungensurfactant zur behandlung von legionärskrankheit |
CA2399944A1 (en) * | 2000-02-11 | 2001-08-16 | Altana Pharma Ag | Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases |
US6660833B1 (en) | 2000-02-29 | 2003-12-09 | Harbor-Ucla Research And Education Institute | Respiratory distress syndrome therapy with peptide analogs of human SP-B |
US20040254112A1 (en) * | 2000-04-12 | 2004-12-16 | Dietrich Hafner | Use of pulmonary surfactant for the early treatment of acute pulmonary diseases |
JP2003530356A (ja) * | 2000-04-12 | 2003-10-14 | アルタナ ファルマ アクチエンゲゼルシャフト | 急性肺疾患の予防又は早期治療のための肺表面活性物質の新規使用 |
DE10018022A1 (de) * | 2000-04-12 | 2001-10-31 | Byk Gulden Lomberg Chem Fab | Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen |
JP4559731B2 (ja) | 2001-10-11 | 2010-10-13 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 肺サーファクタントの新規使用 |
AU2002357168A1 (en) | 2001-12-12 | 2003-07-09 | Penn State Research Foundation | Surfactant prevention of lung complications from cancer chemotherapy |
US8236750B2 (en) * | 2004-08-06 | 2012-08-07 | Nycomed Gmbh | Composition comprising a pulmonary surfactant and a TNF-derived peptide |
US7464012B2 (en) * | 2004-12-10 | 2008-12-09 | L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude | Simplified process simulator |
US7582312B2 (en) | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
US8337815B2 (en) | 2004-12-23 | 2012-12-25 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations |
SI1841458T1 (sl) | 2005-01-06 | 2012-04-30 | Discovery Lab Inc | Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije |
DE102005014650B3 (de) | 2005-03-31 | 2006-08-17 | Altana Pharma Ag | Anordnung aus Katheter und Anschlussstück sowie Ventil zum Durchführen eines Katheters |
DE102005016229B3 (de) | 2005-04-08 | 2006-06-14 | Altana Pharma Ag | Trockenvernebler |
KR20090060348A (ko) * | 2006-09-19 | 2009-06-11 | 디스커버리 래보래토리스, 인크. | 폐 계면활성제 제제 및 점액 클리어런스 촉진 방법 |
US7951781B2 (en) | 2006-11-02 | 2011-05-31 | University Of Iowa Research Foundation | Methods and compositions related to PLUNC surfactant polypeptides |
EP2009023A1 (en) * | 2007-06-04 | 2008-12-31 | Rentschler Beteiligungs GmbH | Novel peptides and their use for the treatment of edema |
US8048043B2 (en) | 2007-06-08 | 2011-11-01 | Chiesi Farmaceutici S. P. A. | Method of administration of a pulmonary surfactant |
CA2744940A1 (en) | 2008-12-10 | 2010-06-17 | Paka Pulmonary Pharmaceuticals, Inc. | Methods and compositions for delivery of medicaments to the lungs |
EP2475373B1 (en) | 2009-09-08 | 2013-11-13 | Chiesi Farmaceutici S.p.A. | A therapeutic combination comprising a pulmonary surfactant and antioxidant enzymes |
EP2608769B1 (en) | 2010-08-23 | 2019-11-06 | Fraunhofer Gesellschaft zur Förderung der Angewand | Humidified particles comprising a therapeutically active substance |
EP3459556A1 (en) * | 2012-02-09 | 2019-03-27 | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Synthetic analogs of lung surfactant protein sp-c and their use |
US20130303726A1 (en) * | 2012-04-17 | 2013-11-14 | Chiesi Farmaceutici S.P.A. | Method for the preparation of surfactant peptides |
WO2013188016A2 (en) | 2012-05-04 | 2013-12-19 | Discovery Laboratories, Inc. | Surfactant therapy for exposure to ionizing radiation |
KR102369135B1 (ko) | 2014-03-05 | 2022-02-28 | 프라운호퍼-게젤샤프트 추르 푀르데룽 데어 안제반텐 포르슝 에 파우 | 에어로졸을 가습하기 위한 가습기 |
ES2827948T3 (es) | 2015-04-22 | 2021-05-25 | Chiesi Farm Spa | Sistema eficaz para la administración de medicamento sincronizada con la respiración a los pulmones |
EP3106090A1 (en) | 2015-06-15 | 2016-12-21 | CHIESI FARMACEUTICI S.p.A. | System for effective breath-synchronized delivery of medicament to the lungs |
WO2016173634A1 (en) | 2015-04-28 | 2016-11-03 | Chiesi Farmaceutici S.P.A | Device for facilitating the administration of a medicament to the lung by a catheter |
EP3288579A1 (en) | 2015-04-30 | 2018-03-07 | University of Bremen | A novel skin medical and cosmetic care product |
MX2019000651A (es) | 2016-07-28 | 2019-04-01 | Chiesi Farm Spa | Metodo y sistema para suministro de medicamento en aerosol. |
CN109890446B (zh) | 2016-10-26 | 2022-03-22 | 奇斯药制品公司 | 用于帮助通过导管向肺给送药剂的装置 |
PL3558376T3 (pl) | 2016-12-22 | 2022-02-14 | Chiesi Farmaceutici S.P.A. | Kombinacja terapeutyczna zawierająca surfaktant płucny i steroid do leczenia rozwijającej się BPD |
CN107163148A (zh) * | 2017-05-15 | 2017-09-15 | 重庆理工大学 | 肺表面活性蛋白b前肽的重组蛋白及其制备方法和应用 |
TW201927286A (zh) | 2017-12-15 | 2019-07-16 | 義大利商凱西製藥公司 | 用於噴霧投藥之包含肺表面張力素的藥學調配物 |
WO2019115771A1 (en) | 2017-12-15 | 2019-06-20 | Pari Pharma Gmbh | Nebuliser system, holding system, combination comprising nebuliser system and holding system, and aerosol administration method |
WO2019206731A1 (en) | 2018-04-23 | 2019-10-31 | Chiesi Farmaceutici S.P.A. | A therapeutic combination comprising a pulmonary surfactant and a steroid for the prophylaxis of bpd |
CN109001466A (zh) * | 2018-07-19 | 2018-12-14 | 新疆维吾尔自治区人民医院 | 一种用于osa的肺表面活性蛋白试剂盒及其应用 |
EP3666315A1 (en) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Aerosol delivery device and method of operating the aerosol delivery device |
EP3666316A1 (en) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Aerosol delivery device and method of operating the aerosol delivery device |
EP3843105A1 (en) | 2019-12-23 | 2021-06-30 | PARI Pharma GmbH | Control device for aerosol nebulizer system |
WO2021151853A1 (en) | 2020-01-28 | 2021-08-05 | Chiesi Farmaceutici S.P.A. | Polypeptides having improved properties |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59164724A (ja) * | 1983-03-10 | 1984-09-17 | Tokyo Tanabe Co Ltd | サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 |
US5169761A (en) * | 1984-12-11 | 1992-12-08 | California Biotechnology Inc. | Dna encoding and expression systems for alveolar surfactant proteins |
US4659805A (en) * | 1984-12-11 | 1987-04-21 | California Biotechnology, Inc. | Recombinant alveolar surfactant protein |
US5104853A (en) * | 1984-12-11 | 1992-04-14 | California Biotechnology Inc. | Alveolar surfactant proteins having cys to ser mutations |
US4933280A (en) * | 1984-12-11 | 1990-06-12 | California Biotechnology Inc. | Recombinant DNA sequence encoding Alveolar Surfactant Protein |
US5013720A (en) * | 1986-05-06 | 1991-05-07 | Abbott Laboratories | SAP-6-Val proteins and methods |
JP2602968B2 (ja) * | 1987-11-04 | 1997-04-23 | カリフォルニア バイオテクノロジー インコーポレイテッド | 肺胞の界面活性タンパク類 |
SE8803713D0 (sv) * | 1988-10-18 | 1988-10-18 | Kabigen Ab | Biologically active lipoprotein and its use |
DE3921954A1 (de) * | 1989-07-04 | 1991-01-17 | Thomae Gmbh Dr K | Niedrig-viskose, hochkonzentrierte surfactant-suspension |
JPH05294996A (ja) * | 1992-04-17 | 1993-11-09 | Tokyo Tanabe Co Ltd | 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤 |
-
1994
- 1994-05-31 DE DE4418936A patent/DE4418936A1/de not_active Withdrawn
-
1995
- 1995-05-27 BR BRPI9507811-8A patent/BR9507811B1/pt not_active IP Right Cessation
- 1995-05-27 EE EE9600175A patent/EE03775B1/xx unknown
- 1995-05-27 CN CN95194374A patent/CN1130374C/zh not_active Expired - Lifetime
- 1995-05-27 SK SK1524-96A patent/SK282441B6/sk not_active IP Right Cessation
- 1995-05-27 PL PL95317420A patent/PL181234B1/pl unknown
- 1995-05-27 AT AT95920906T patent/ATE275154T1/de active
- 1995-05-27 ES ES95920906T patent/ES2227548T3/es not_active Expired - Lifetime
- 1995-05-27 CZ CZ19963502A patent/CZ286976B6/cs not_active IP Right Cessation
- 1995-05-27 CA CA002191344A patent/CA2191344C/en not_active Expired - Lifetime
- 1995-05-27 NZ NZ287447A patent/NZ287447A/en not_active IP Right Cessation
- 1995-05-27 JP JP50030596A patent/JP3359638B2/ja not_active Expired - Lifetime
- 1995-05-27 DE DE59510941T patent/DE59510941D1/de not_active Expired - Lifetime
- 1995-05-27 US US08/750,194 patent/US5874406A/en not_active Expired - Lifetime
- 1995-05-27 EP EP95920906A patent/EP0764172B1/de not_active Expired - Lifetime
- 1995-05-27 AU AU26169/95A patent/AU690280B2/en not_active Expired
- 1995-05-27 RO RO96-02248A patent/RO118752B1/ro unknown
- 1995-05-27 WO PCT/EP1995/002028 patent/WO1995032992A1/de active IP Right Grant
- 1995-05-27 RU RU96124768A patent/RU2145611C1/ru active
- 1995-05-27 SI SI9530712T patent/SI0764172T1/xx unknown
- 1995-05-27 KR KR1019960706778A patent/KR100355626B1/ko not_active IP Right Cessation
- 1995-05-27 HU HU9603249A patent/HU220191B/hu unknown
- 1995-05-27 PT PT95920906T patent/PT764172E/pt unknown
- 1995-05-27 UA UA96114479A patent/UA35636C2/uk unknown
- 1995-05-27 DK DK95920906T patent/DK0764172T3/da active
-
1996
- 1996-11-27 NO NO19965052A patent/NO317149B1/no not_active IP Right Cessation
- 1996-11-29 FI FI964766A patent/FI118126B/fi not_active IP Right Cessation
- 1996-12-04 BG BG101028A patent/BG63210B1/bg unknown
-
1997
- 1997-12-18 HK HK97102503A patent/HK1000891A1/xx not_active IP Right Cessation
-
2006
- 2006-02-20 CY CY0600006A patent/CY2552B1/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TC4A | Change of owner's name |
Owner name: TAKEDA GMBH, KONSTANZ, DE Effective date: 20130725 |
|
MK4A | Patent expired |
Expiry date: 20150527 |