SK282441B6 - Polypeptid s aktivitou pľúcneho surfaktantu a farmaceutický prostriedok s jeho obsahom - Google Patents

Polypeptid s aktivitou pľúcneho surfaktantu a farmaceutický prostriedok s jeho obsahom Download PDF

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Publication number
SK282441B6
SK282441B6 SK1524-96A SK152496A SK282441B6 SK 282441 B6 SK282441 B6 SK 282441B6 SK 152496 A SK152496 A SK 152496A SK 282441 B6 SK282441 B6 SK 282441B6
Authority
SK
Slovakia
Prior art keywords
phe
leu
polypeptide
surfactant
pharmaceutical composition
Prior art date
Application number
SK1524-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK152496A3 (en
Inventor
R�diger NAVE
Wolf-R�diger ULRICH
Ernst Sturm
Uwe KR�GER
Dietrich H�FNER
Klaus P. SCH�FER
Klaus Melchers
Original Assignee
Byk Gulden Lomberg Chemische Fabrik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6519392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK282441(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh
Publication of SK152496A3 publication Critical patent/SK152496A3/sk
Publication of SK282441B6 publication Critical patent/SK282441B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK1524-96A 1994-05-31 1995-05-27 Polypeptid s aktivitou pľúcneho surfaktantu a farmaceutický prostriedok s jeho obsahom SK282441B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4418936A DE4418936A1 (de) 1994-05-31 1994-05-31 Polypeptid
PCT/EP1995/002028 WO1995032992A1 (de) 1994-05-31 1995-05-27 Synthetische peptidanaloge des lungenoberflächenproteins sp-c

Publications (2)

Publication Number Publication Date
SK152496A3 SK152496A3 (en) 1997-06-04
SK282441B6 true SK282441B6 (sk) 2002-02-05

Family

ID=6519392

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1524-96A SK282441B6 (sk) 1994-05-31 1995-05-27 Polypeptid s aktivitou pľúcneho surfaktantu a farmaceutický prostriedok s jeho obsahom

Country Status (29)

Country Link
US (1) US5874406A (pt)
EP (1) EP0764172B1 (pt)
JP (1) JP3359638B2 (pt)
KR (1) KR100355626B1 (pt)
CN (1) CN1130374C (pt)
AT (1) ATE275154T1 (pt)
AU (1) AU690280B2 (pt)
BG (1) BG63210B1 (pt)
BR (1) BR9507811B1 (pt)
CA (1) CA2191344C (pt)
CY (1) CY2552B1 (pt)
CZ (1) CZ286976B6 (pt)
DE (2) DE4418936A1 (pt)
DK (1) DK0764172T3 (pt)
EE (1) EE03775B1 (pt)
ES (1) ES2227548T3 (pt)
FI (1) FI118126B (pt)
HK (1) HK1000891A1 (pt)
HU (1) HU220191B (pt)
NO (1) NO317149B1 (pt)
NZ (1) NZ287447A (pt)
PL (1) PL181234B1 (pt)
PT (1) PT764172E (pt)
RO (1) RO118752B1 (pt)
RU (1) RU2145611C1 (pt)
SI (1) SI0764172T1 (pt)
SK (1) SK282441B6 (pt)
UA (1) UA35636C2 (pt)
WO (1) WO1995032992A1 (pt)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2322097A (en) * 1996-03-27 1997-10-17 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
DE19851119C2 (de) 1998-11-06 2001-05-31 Byk Gulden Lomberg Chem Fab Behälter und Vorrichtung zur Blindung der Verabreichung von nicht festen pharmazeutischen Darreichungsformen bei der klinischen Prüfung
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
WO2000076535A1 (en) * 1999-06-11 2000-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
CA2375214C (en) * 1999-06-17 2012-01-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Surfactant protein c esters
AU6083899A (en) 1999-09-16 2001-04-17 Aventis Behring Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
WO2001039573A2 (de) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung von lungensurfactant zur behandlung von legionärskrankheit
CA2399944A1 (en) * 2000-02-11 2001-08-16 Altana Pharma Ag Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases
US6660833B1 (en) 2000-02-29 2003-12-09 Harbor-Ucla Research And Education Institute Respiratory distress syndrome therapy with peptide analogs of human SP-B
US20040254112A1 (en) * 2000-04-12 2004-12-16 Dietrich Hafner Use of pulmonary surfactant for the early treatment of acute pulmonary diseases
JP2003530356A (ja) * 2000-04-12 2003-10-14 アルタナ ファルマ アクチエンゲゼルシャフト 急性肺疾患の予防又は早期治療のための肺表面活性物質の新規使用
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
JP4559731B2 (ja) 2001-10-11 2010-10-13 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺サーファクタントの新規使用
AU2002357168A1 (en) 2001-12-12 2003-07-09 Penn State Research Foundation Surfactant prevention of lung complications from cancer chemotherapy
US8236750B2 (en) * 2004-08-06 2012-08-07 Nycomed Gmbh Composition comprising a pulmonary surfactant and a TNF-derived peptide
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US8337815B2 (en) 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
SI1841458T1 (sl) 2005-01-06 2012-04-30 Discovery Lab Inc Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije
DE102005014650B3 (de) 2005-03-31 2006-08-17 Altana Pharma Ag Anordnung aus Katheter und Anschlussstück sowie Ventil zum Durchführen eines Katheters
DE102005016229B3 (de) 2005-04-08 2006-06-14 Altana Pharma Ag Trockenvernebler
KR20090060348A (ko) * 2006-09-19 2009-06-11 디스커버리 래보래토리스, 인크. 폐 계면활성제 제제 및 점액 클리어런스 촉진 방법
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
US8048043B2 (en) 2007-06-08 2011-11-01 Chiesi Farmaceutici S. P. A. Method of administration of a pulmonary surfactant
CA2744940A1 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
EP2475373B1 (en) 2009-09-08 2013-11-13 Chiesi Farmaceutici S.p.A. A therapeutic combination comprising a pulmonary surfactant and antioxidant enzymes
EP2608769B1 (en) 2010-08-23 2019-11-06 Fraunhofer Gesellschaft zur Förderung der Angewand Humidified particles comprising a therapeutically active substance
EP3459556A1 (en) * 2012-02-09 2019-03-27 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Synthetic analogs of lung surfactant protein sp-c and their use
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation
KR102369135B1 (ko) 2014-03-05 2022-02-28 프라운호퍼-게젤샤프트 추르 푀르데룽 데어 안제반텐 포르슝 에 파우 에어로졸을 가습하기 위한 가습기
ES2827948T3 (es) 2015-04-22 2021-05-25 Chiesi Farm Spa Sistema eficaz para la administración de medicamento sincronizada con la respiración a los pulmones
EP3106090A1 (en) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. System for effective breath-synchronized delivery of medicament to the lungs
WO2016173634A1 (en) 2015-04-28 2016-11-03 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
EP3288579A1 (en) 2015-04-30 2018-03-07 University of Bremen A novel skin medical and cosmetic care product
MX2019000651A (es) 2016-07-28 2019-04-01 Chiesi Farm Spa Metodo y sistema para suministro de medicamento en aerosol.
CN109890446B (zh) 2016-10-26 2022-03-22 奇斯药制品公司 用于帮助通过导管向肺给送药剂的装置
PL3558376T3 (pl) 2016-12-22 2022-02-14 Chiesi Farmaceutici S.P.A. Kombinacja terapeutyczna zawierająca surfaktant płucny i steroid do leczenia rozwijającej się BPD
CN107163148A (zh) * 2017-05-15 2017-09-15 重庆理工大学 肺表面活性蛋白b前肽的重组蛋白及其制备方法和应用
TW201927286A (zh) 2017-12-15 2019-07-16 義大利商凱西製藥公司 用於噴霧投藥之包含肺表面張力素的藥學調配物
WO2019115771A1 (en) 2017-12-15 2019-06-20 Pari Pharma Gmbh Nebuliser system, holding system, combination comprising nebuliser system and holding system, and aerosol administration method
WO2019206731A1 (en) 2018-04-23 2019-10-31 Chiesi Farmaceutici S.P.A. A therapeutic combination comprising a pulmonary surfactant and a steroid for the prophylaxis of bpd
CN109001466A (zh) * 2018-07-19 2018-12-14 新疆维吾尔自治区人民医院 一种用于osa的肺表面活性蛋白试剂盒及其应用
EP3666315A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3666316A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3843105A1 (en) 2019-12-23 2021-06-30 PARI Pharma GmbH Control device for aerosol nebulizer system
WO2021151853A1 (en) 2020-01-28 2021-08-05 Chiesi Farmaceutici S.P.A. Polypeptides having improved properties

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US5104853A (en) * 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
JP2602968B2 (ja) * 1987-11-04 1997-04-23 カリフォルニア バイオテクノロジー インコーポレイテッド 肺胞の界面活性タンパク類
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE3921954A1 (de) * 1989-07-04 1991-01-17 Thomae Gmbh Dr K Niedrig-viskose, hochkonzentrierte surfactant-suspension
JPH05294996A (ja) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤

Also Published As

Publication number Publication date
PT764172E (pt) 2005-01-31
SI0764172T1 (en) 2005-02-28
BG101028A (en) 1998-01-30
KR100355626B1 (ko) 2002-12-26
DE4418936A1 (de) 1996-02-08
EP0764172B1 (de) 2004-09-01
HU220191B (hu) 2001-11-28
RO118752B1 (ro) 2003-10-30
NO965052D0 (no) 1996-11-27
EP0764172A1 (de) 1997-03-26
HK1000891A1 (en) 2004-09-17
FI118126B (fi) 2007-07-13
NZ287447A (en) 1998-01-26
CA2191344C (en) 2003-04-08
CN1130374C (zh) 2003-12-10
CN1154117A (zh) 1997-07-09
FI964766A0 (fi) 1996-11-29
BR9507811A (pt) 1997-09-16
CY2552B1 (en) 2008-07-02
SK152496A3 (en) 1997-06-04
CZ350296A3 (en) 1997-05-14
BR9507811B1 (pt) 2009-05-05
JPH10504025A (ja) 1998-04-14
FI964766A (fi) 1996-11-29
ES2227548T3 (es) 2005-04-01
NO965052L (no) 1997-01-28
UA35636C2 (uk) 2001-04-16
WO1995032992A1 (de) 1995-12-07
JP3359638B2 (ja) 2002-12-24
DE59510941D1 (de) 2004-10-07
HUT76952A (hu) 1998-01-28
PL317420A1 (en) 1997-04-14
RU2145611C1 (ru) 2000-02-20
AU2616995A (en) 1995-12-21
DK0764172T3 (da) 2005-01-10
ATE275154T1 (de) 2004-09-15
NO317149B1 (no) 2004-08-30
US5874406A (en) 1999-02-23
BG63210B1 (bg) 2001-06-29
CZ286976B6 (en) 2000-08-16
HU9603249D0 (en) 1997-01-28
EE9600175A (et) 1997-06-16
EE03775B1 (et) 2002-06-17
PL181234B1 (pl) 2001-06-29
KR970703367A (ko) 1997-07-03
AU690280B2 (en) 1998-04-23
MX9605986A (es) 1998-06-30
CA2191344A1 (en) 1995-12-07

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Legal Events

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TC4A Change of owner's name

Owner name: TAKEDA GMBH, KONSTANZ, DE

Effective date: 20130725

MK4A Patent expired

Expiry date: 20150527