BR9507811A - Análogs de pertídeos sintéticos da proteína superficial dos pulmões sp-c - Google Patents
Análogs de pertídeos sintéticos da proteína superficial dos pulmões sp-cInfo
- Publication number
- BR9507811A BR9507811A BR9507811A BR9507811A BR9507811A BR 9507811 A BR9507811 A BR 9507811A BR 9507811 A BR9507811 A BR 9507811A BR 9507811 A BR9507811 A BR 9507811A BR 9507811 A BR9507811 A BR 9507811A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- image
- analogs
- pertides
- lungs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4418936A DE4418936A1 (de) | 1994-05-31 | 1994-05-31 | Polypeptid |
PCT/EP1995/002028 WO1995032992A1 (de) | 1994-05-31 | 1995-05-27 | Synthetische peptidanaloge des lungenoberflächenproteins sp-c |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9507811A true BR9507811A (pt) | 1997-09-16 |
BR9507811B1 BR9507811B1 (pt) | 2009-05-05 |
Family
ID=6519392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9507811-8A BR9507811B1 (pt) | 1994-05-31 | 1995-05-27 | polipeptìdeos e composição farmacêutica. |
Country Status (29)
Country | Link |
---|---|
US (1) | US5874406A (pt) |
EP (1) | EP0764172B1 (pt) |
JP (1) | JP3359638B2 (pt) |
KR (1) | KR100355626B1 (pt) |
CN (1) | CN1130374C (pt) |
AT (1) | ATE275154T1 (pt) |
AU (1) | AU690280B2 (pt) |
BG (1) | BG63210B1 (pt) |
BR (1) | BR9507811B1 (pt) |
CA (1) | CA2191344C (pt) |
CY (1) | CY2552B1 (pt) |
CZ (1) | CZ286976B6 (pt) |
DE (2) | DE4418936A1 (pt) |
DK (1) | DK0764172T3 (pt) |
EE (1) | EE03775B1 (pt) |
ES (1) | ES2227548T3 (pt) |
FI (1) | FI118126B (pt) |
HK (1) | HK1000891A1 (pt) |
HU (1) | HU220191B (pt) |
NO (1) | NO317149B1 (pt) |
NZ (1) | NZ287447A (pt) |
PL (1) | PL181234B1 (pt) |
PT (1) | PT764172E (pt) |
RO (1) | RO118752B1 (pt) |
RU (1) | RU2145611C1 (pt) |
SI (1) | SI0764172T1 (pt) |
SK (1) | SK282441B6 (pt) |
UA (1) | UA35636C2 (pt) |
WO (1) | WO1995032992A1 (pt) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2322097A (en) * | 1996-03-27 | 1997-10-17 | Ortho Pharmaceutical Corporation | Lyophilized pulmonary surfactant peptide compositions |
DE19851119C2 (de) | 1998-11-06 | 2001-05-31 | Byk Gulden Lomberg Chem Fab | Behälter und Vorrichtung zur Blindung der Verabreichung von nicht festen pharmazeutischen Darreichungsformen bei der klinischen Prüfung |
IT1308180B1 (it) * | 1999-02-12 | 2001-12-07 | Chiesi Farma Spa | Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante |
AU5400000A (en) * | 1999-06-11 | 2001-01-02 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c) |
US7022671B1 (en) * | 1999-06-17 | 2006-04-04 | Altana Pharma Ag | Surfactant protein C esters |
WO2001019392A1 (en) | 1999-09-16 | 2001-03-22 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Combination of c1-inh and lung surfactant for the treatment of respiratory disorders |
AU2003201A (en) * | 1999-12-01 | 2001-06-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel use of lung surfactant |
AU2001233757A1 (en) * | 2000-02-11 | 2001-08-20 | Altana Pharma Ag | Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases |
US6660833B1 (en) * | 2000-02-29 | 2003-12-09 | Harbor-Ucla Research And Education Institute | Respiratory distress syndrome therapy with peptide analogs of human SP-B |
DE10018022A1 (de) * | 2000-04-12 | 2001-10-31 | Byk Gulden Lomberg Chem Fab | Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen |
US20040254112A1 (en) * | 2000-04-12 | 2004-12-16 | Dietrich Hafner | Use of pulmonary surfactant for the early treatment of acute pulmonary diseases |
DE60118898T2 (de) * | 2000-04-12 | 2006-11-16 | Altana Pharma Ag | Verwendung von rekombinantem lungensurfactant zur frühbehandlung von akuten lungenerkrankungen |
ATE468131T1 (de) | 2001-10-11 | 2010-06-15 | Nycomed Gmbh | Neue verwendung von lungensurfactant |
US6998384B2 (en) | 2001-12-12 | 2006-02-14 | The Penn State Research Foundation | Surfactant prevention of lung complications from cancer chemotherapy |
JP5108515B2 (ja) | 2004-08-06 | 2012-12-26 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 肺サーファクタント及びtnf由来ペプチドを含有する組成物 |
US7464012B2 (en) * | 2004-12-10 | 2008-12-09 | L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude | Simplified process simulator |
US7582312B2 (en) * | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
US8337815B2 (en) | 2004-12-23 | 2012-12-25 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations |
US7541331B2 (en) | 2005-01-06 | 2009-06-02 | Discovery Laboratories, Inc. | Surfactant treatment regimen |
DE102005014650B3 (de) | 2005-03-31 | 2006-08-17 | Altana Pharma Ag | Anordnung aus Katheter und Anschlussstück sowie Ventil zum Durchführen eines Katheters |
DE102005016229B3 (de) | 2005-04-08 | 2006-06-14 | Altana Pharma Ag | Trockenvernebler |
WO2008036293A1 (en) * | 2006-09-19 | 2008-03-27 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations and methods for promoting mucus clearance |
US7951781B2 (en) | 2006-11-02 | 2011-05-31 | University Of Iowa Research Foundation | Methods and compositions related to PLUNC surfactant polypeptides |
EP2009023A1 (en) * | 2007-06-04 | 2008-12-31 | Rentschler Beteiligungs GmbH | Novel peptides and their use for the treatment of edema |
US8048043B2 (en) | 2007-06-08 | 2011-11-01 | Chiesi Farmaceutici S. P. A. | Method of administration of a pulmonary surfactant |
CA2744940A1 (en) | 2008-12-10 | 2010-06-17 | Paka Pulmonary Pharmaceuticals, Inc. | Methods and compositions for delivery of medicaments to the lungs |
WO2011029525A1 (en) | 2009-09-08 | 2011-03-17 | Chiesi Farmaceutici S.P.A. | A therapeutic combination comprising a pulmonary surfactant and antioxidant enzymes |
US9693955B2 (en) * | 2010-08-23 | 2017-07-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Humidified particles comprising a therapeutically active substance |
EP3459556A1 (en) * | 2012-02-09 | 2019-03-27 | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Synthetic analogs of lung surfactant protein sp-c and their use |
US20130303726A1 (en) * | 2012-04-17 | 2013-11-14 | Chiesi Farmaceutici S.P.A. | Method for the preparation of surfactant peptides |
WO2013188016A2 (en) | 2012-05-04 | 2013-12-19 | Discovery Laboratories, Inc. | Surfactant therapy for exposure to ionizing radiation |
WO2015132172A1 (en) | 2014-03-05 | 2015-09-11 | Takeda Gmbh | Humidifier for humidifying an aerosol |
WO2016170087A1 (en) | 2015-04-22 | 2016-10-27 | Chiesi Farmaceutici S.P.A | Method and system for effective breath-synchronized delivery of medicament to the lungs |
EP3106090A1 (en) | 2015-06-15 | 2016-12-21 | CHIESI FARMACEUTICI S.p.A. | System for effective breath-synchronized delivery of medicament to the lungs |
WO2016173634A1 (en) | 2015-04-28 | 2016-11-03 | Chiesi Farmaceutici S.P.A | Device for facilitating the administration of a medicament to the lung by a catheter |
CN107979996A (zh) * | 2015-04-30 | 2018-05-01 | 不莱梅大学 | 新的皮肤医疗和美容护理产品 |
EP3490649A1 (en) | 2016-07-28 | 2019-06-05 | Chiesi Farmaceutici S.p.A. | Method and system for delivery of an aerosolized medicament |
CN109890446B (zh) | 2016-10-26 | 2022-03-22 | 奇斯药制品公司 | 用于帮助通过导管向肺给送药剂的装置 |
AU2017384467B2 (en) | 2016-12-22 | 2023-10-19 | Chiesi Farmaceutici S.P.A. | A therapeutic combination comprising a pulmonary surfactant and a steroid for the treatment of evolving BPD |
CN107163148A (zh) * | 2017-05-15 | 2017-09-15 | 重庆理工大学 | 肺表面活性蛋白b前肽的重组蛋白及其制备方法和应用 |
TW201927286A (zh) | 2017-12-15 | 2019-07-16 | 義大利商凱西製藥公司 | 用於噴霧投藥之包含肺表面張力素的藥學調配物 |
WO2019115771A1 (en) | 2017-12-15 | 2019-06-20 | Pari Pharma Gmbh | Nebuliser system, holding system, combination comprising nebuliser system and holding system, and aerosol administration method |
JP7378425B2 (ja) | 2018-04-23 | 2023-11-13 | シエシー ファルマセウティチィ ソシエタ ペル アチオニ | 肺サーファクタントおよびbpdの予防のためのステロイドを含む治療的組合せ |
CN109001466A (zh) * | 2018-07-19 | 2018-12-14 | 新疆维吾尔自治区人民医院 | 一种用于osa的肺表面活性蛋白试剂盒及其应用 |
EP3666316A1 (en) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Aerosol delivery device and method of operating the aerosol delivery device |
EP3666315A1 (en) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Aerosol delivery device and method of operating the aerosol delivery device |
EP3843105A1 (en) | 2019-12-23 | 2021-06-30 | PARI Pharma GmbH | Control device for aerosol nebulizer system |
WO2021151853A1 (en) | 2020-01-28 | 2021-08-05 | Chiesi Farmaceutici S.P.A. | Polypeptides having improved properties |
EP4411745A1 (en) | 2023-02-01 | 2024-08-07 | Pari Medical Holding GmbH | Medical evaluation method, aerosol nebulizer and medical evaluation system |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59164724A (ja) * | 1983-03-10 | 1984-09-17 | Tokyo Tanabe Co Ltd | サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 |
US5104853A (en) * | 1984-12-11 | 1992-04-14 | California Biotechnology Inc. | Alveolar surfactant proteins having cys to ser mutations |
US4933280A (en) * | 1984-12-11 | 1990-06-12 | California Biotechnology Inc. | Recombinant DNA sequence encoding Alveolar Surfactant Protein |
US4659805A (en) * | 1984-12-11 | 1987-04-21 | California Biotechnology, Inc. | Recombinant alveolar surfactant protein |
US5169761A (en) * | 1984-12-11 | 1992-12-08 | California Biotechnology Inc. | Dna encoding and expression systems for alveolar surfactant proteins |
US5013720A (en) * | 1986-05-06 | 1991-05-07 | Abbott Laboratories | SAP-6-Val proteins and methods |
ATE163013T1 (de) * | 1987-11-04 | 1998-02-15 | Byk Gulden Lomberg Chem Fab | Alveolare oberflächenaktive proteine |
SE8803713D0 (sv) * | 1988-10-18 | 1988-10-18 | Kabigen Ab | Biologically active lipoprotein and its use |
DE3921954A1 (de) * | 1989-07-04 | 1991-01-17 | Thomae Gmbh Dr K | Niedrig-viskose, hochkonzentrierte surfactant-suspension |
JPH05294996A (ja) * | 1992-04-17 | 1993-11-09 | Tokyo Tanabe Co Ltd | 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤 |
-
1994
- 1994-05-31 DE DE4418936A patent/DE4418936A1/de not_active Withdrawn
-
1995
- 1995-05-27 RO RO96-02248A patent/RO118752B1/ro unknown
- 1995-05-27 PT PT95920906T patent/PT764172E/pt unknown
- 1995-05-27 EP EP95920906A patent/EP0764172B1/de not_active Expired - Lifetime
- 1995-05-27 NZ NZ287447A patent/NZ287447A/en not_active IP Right Cessation
- 1995-05-27 SI SI9530712T patent/SI0764172T1/xx unknown
- 1995-05-27 ES ES95920906T patent/ES2227548T3/es not_active Expired - Lifetime
- 1995-05-27 US US08/750,194 patent/US5874406A/en not_active Expired - Lifetime
- 1995-05-27 AT AT95920906T patent/ATE275154T1/de active
- 1995-05-27 JP JP50030596A patent/JP3359638B2/ja not_active Expired - Lifetime
- 1995-05-27 EE EE9600175A patent/EE03775B1/xx unknown
- 1995-05-27 DE DE59510941T patent/DE59510941D1/de not_active Expired - Lifetime
- 1995-05-27 WO PCT/EP1995/002028 patent/WO1995032992A1/de active IP Right Grant
- 1995-05-27 DK DK95920906T patent/DK0764172T3/da active
- 1995-05-27 AU AU26169/95A patent/AU690280B2/en not_active Expired
- 1995-05-27 KR KR1019960706778A patent/KR100355626B1/ko not_active IP Right Cessation
- 1995-05-27 PL PL95317420A patent/PL181234B1/pl unknown
- 1995-05-27 BR BRPI9507811-8A patent/BR9507811B1/pt not_active IP Right Cessation
- 1995-05-27 CA CA002191344A patent/CA2191344C/en not_active Expired - Lifetime
- 1995-05-27 RU RU96124768A patent/RU2145611C1/ru active
- 1995-05-27 HU HU9603249A patent/HU220191B/hu unknown
- 1995-05-27 SK SK1524-96A patent/SK282441B6/sk not_active IP Right Cessation
- 1995-05-27 CN CN95194374A patent/CN1130374C/zh not_active Expired - Lifetime
- 1995-05-27 CZ CZ19963502A patent/CZ286976B6/cs not_active IP Right Cessation
- 1995-05-27 UA UA96114479A patent/UA35636C2/uk unknown
-
1996
- 1996-11-27 NO NO19965052A patent/NO317149B1/no not_active IP Right Cessation
- 1996-11-29 FI FI964766A patent/FI118126B/fi not_active IP Right Cessation
- 1996-12-04 BG BG101028A patent/BG63210B1/bg unknown
-
1997
- 1997-12-18 HK HK97102503A patent/HK1000891A1/xx not_active IP Right Cessation
-
2006
- 2006-02-20 CY CY0600006A patent/CY2552B1/xx unknown
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Legal Events
Date | Code | Title | Description |
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B25D | Requested change of name of applicant approved | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: O REQUERENTE DEVERA COMPLEMENTAR A TAXA RELATIVA A 1 REVINDICACAO EXEDENTE. O PEDIDO DE EXAME ( FOLHA 52 ) REFERE-SE A 11 REVINDICACOES, POREM O REQUERENTE DEPOSITOU 12 REVINDICACOES ( FOLHAS 136 E138 ). |
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B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B25D | Requested change of name of applicant approved |
Owner name: NYCOMED GMBH (DE) Free format text: ALTERADO DE: ALTANA PHARMA AG |
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B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 28/07/2009, OBSERVADAS AS CONDICOES LEGAIS. |
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B22O | Other matters related to patents and certificates of addition of invention: legal action concerning patent |
Free format text: INPI-52400.061558/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO0132272-32.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: NYCOMED GMBH, OKLAHOMA STATE UNIVERSITY, REGESTS OF THE UNIVERSITY OF MINNESOTA, OTSUKA PHARMACEUTICAL CO LTD, PLASMASEAL CORPORATION |
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B21B | Extinction acc. art. 78, item ii - on waiver by the patentee, without prejudice to the rights of third parties |
Free format text: SOLICITADA ATRAVES DA PETICAO 860130004420, DE 14/10/2013 |
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B15G | Petition not considered as such [chapter 15.7 patent gazette] |
Free format text: A PETICAO DE NO 20130064421, APRESENTADA EM 23/07/2013, EM VIRTUDE DO DISPOSTO NOS ARTS. 218 OU 219 DA LPI (LEI 9279 / 96) DE 14/05/1996, E CONSIDERADA COMO PETICAO NAO CONHECIDA EM VIRTUDE DA EXTINCAO DA PATENTE PUBLICADA NA RPI NO 2241, DE 17/12/2013. |
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B19A | Notification of judicial decision: notification of judicial decision |
Free format text: INPI-52400.061558/2013-85 13A VARA FEDERAL DO RIO DE JANEIRO ORDINARIA / PROPRIEDADE INDUSTRIAL PROCESSO : 0132272-32.2013.4.02.5101 (2013.51.01.132272-3) AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL INPI REU: REGENTS OF THE UNIVERSITY OF MINNESOTA, OKLAHOMA STATE UNIVERSITY, OTSUKA PHARMACEUTICAL CO. LTD., PLASMASEAL CORPORATION E NYCOMED GMBH. DECISAO: HOMOLOGO, POR SENTENCA, PARA QUE SE PRODUZA OS SEUS JURIDICOS E LEGAIS EFEITOS, OS ACORDOS FIRMADOS ENTRE O INPI E AS RES, CONFORME FLS. 87/89, 93/96, 138/139, 192/193 E 245, JULGANDO EXTINTO O PROCESSO, COM RESOLUCAO DO MERITO, NOS MOLDES DO ARTIGO 269, III DO CODIGO DO PROCESSO CIVIL, EM RELACAO AS ALUDIDAS EMPRESAS RES E AO |
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B25E | Requested change of name of applicant rejected |
Owner name: NYCOMED GMBH (DE) |