BR9507811A - Análogs de pertídeos sintéticos da proteína superficial dos pulmões sp-c - Google Patents

Análogs de pertídeos sintéticos da proteína superficial dos pulmões sp-c

Info

Publication number
BR9507811A
BR9507811A BR9507811A BR9507811A BR9507811A BR 9507811 A BR9507811 A BR 9507811A BR 9507811 A BR9507811 A BR 9507811A BR 9507811 A BR9507811 A BR 9507811A BR 9507811 A BR9507811 A BR 9507811A
Authority
BR
Brazil
Prior art keywords
pct
image
analogs
pertides
lungs
Prior art date
Application number
BR9507811A
Other languages
English (en)
Other versions
BR9507811B1 (pt
Inventor
Klaus P Schaefer
Klaus Melchers
Ruediger Nave
Wolf-Ruediger Ulrich
Ernst Sturm
Uwe Krueger
Dietrich Haefner
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6519392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9507811(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of BR9507811A publication Critical patent/BR9507811A/pt
Publication of BR9507811B1 publication Critical patent/BR9507811B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
BRPI9507811-8A 1994-05-31 1995-05-27 polipeptìdeos e composição farmacêutica. BR9507811B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4418936A DE4418936A1 (de) 1994-05-31 1994-05-31 Polypeptid
PCT/EP1995/002028 WO1995032992A1 (de) 1994-05-31 1995-05-27 Synthetische peptidanaloge des lungenoberflächenproteins sp-c

Publications (2)

Publication Number Publication Date
BR9507811A true BR9507811A (pt) 1997-09-16
BR9507811B1 BR9507811B1 (pt) 2009-05-05

Family

ID=6519392

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9507811-8A BR9507811B1 (pt) 1994-05-31 1995-05-27 polipeptìdeos e composição farmacêutica.

Country Status (29)

Country Link
US (1) US5874406A (pt)
EP (1) EP0764172B1 (pt)
JP (1) JP3359638B2 (pt)
KR (1) KR100355626B1 (pt)
CN (1) CN1130374C (pt)
AT (1) ATE275154T1 (pt)
AU (1) AU690280B2 (pt)
BG (1) BG63210B1 (pt)
BR (1) BR9507811B1 (pt)
CA (1) CA2191344C (pt)
CY (1) CY2552B1 (pt)
CZ (1) CZ286976B6 (pt)
DE (2) DE4418936A1 (pt)
DK (1) DK0764172T3 (pt)
EE (1) EE03775B1 (pt)
ES (1) ES2227548T3 (pt)
FI (1) FI118126B (pt)
HK (1) HK1000891A1 (pt)
HU (1) HU220191B (pt)
NO (1) NO317149B1 (pt)
NZ (1) NZ287447A (pt)
PL (1) PL181234B1 (pt)
PT (1) PT764172E (pt)
RO (1) RO118752B1 (pt)
RU (1) RU2145611C1 (pt)
SI (1) SI0764172T1 (pt)
SK (1) SK282441B6 (pt)
UA (1) UA35636C2 (pt)
WO (1) WO1995032992A1 (pt)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035882A1 (en) * 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
DE19851119C2 (de) 1998-11-06 2001-05-31 Byk Gulden Lomberg Chem Fab Behälter und Vorrichtung zur Blindung der Verabreichung von nicht festen pharmazeutischen Darreichungsformen bei der klinischen Prüfung
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
CA2372558A1 (en) * 1999-06-11 2000-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
AU5074400A (en) * 1999-06-17 2001-01-09 Byk Gulden Lomberg Chemische Fabrik Gmbh Surfactant protein c esters
CA2384861A1 (en) 1999-09-16 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
WO2001039573A2 (de) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung von lungensurfactant zur behandlung von legionärskrankheit
US20030091509A1 (en) * 2000-02-11 2003-05-15 Haefner Dietrich Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases
US6660833B1 (en) 2000-02-29 2003-12-09 Harbor-Ucla Research And Education Institute Respiratory distress syndrome therapy with peptide analogs of human SP-B
CA2405811C (en) * 2000-04-12 2011-09-27 Altana Pharma Ag Novel use of pulmonary surfactant for the prophylaxis or early treatment of acute pulmonary diseases
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
US20040254112A1 (en) * 2000-04-12 2004-12-16 Dietrich Hafner Use of pulmonary surfactant for the early treatment of acute pulmonary diseases
AU2002338882B2 (en) 2001-10-11 2008-04-03 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Novel use of pulmonary surfactant
AU2002357168A1 (en) 2001-12-12 2003-07-09 Penn State Research Foundation Surfactant prevention of lung complications from cancer chemotherapy
AU2005268755B2 (en) 2004-08-06 2011-04-07 Takeda Gmbh Composition comprising a pulmonary surfactant and a TNF-derived peptide
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US8337815B2 (en) 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
AU2006203978B2 (en) 2005-01-06 2011-11-03 Discovery Laboratories, Inc. Surfactant treatment regimen for treating or preventing bronchopulmonary dysplasia
DE102005014650B3 (de) * 2005-03-31 2006-08-17 Altana Pharma Ag Anordnung aus Katheter und Anschlussstück sowie Ventil zum Durchführen eines Katheters
DE102005016229B3 (de) 2005-04-08 2006-06-14 Altana Pharma Ag Trockenvernebler
MX2009003002A (es) * 2006-09-19 2009-06-01 Discovery Lab Inc Formulaciones de tensioactivos pulmonares y metodos para promover la aclaracion del moco.
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
US8048043B2 (en) 2007-06-08 2011-11-01 Chiesi Farmaceutici S. P. A. Method of administration of a pulmonary surfactant
AU2009324637B2 (en) 2008-12-10 2016-09-08 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
BR112012004651B1 (pt) 2009-09-08 2022-02-08 Chiesi Farmaceutici S.P.A. Surfactante pulmonar exógeno, uso de uma combinação terapêutica, medicamento e kit
WO2012025496A1 (en) 2010-08-23 2012-03-01 Nycomed Gmbh Humidified particles comprising a therapeutically active substance
US9815869B2 (en) * 2012-02-09 2017-11-14 University Of Rochester SP-B and SP-C peptides, synthetic lung surfactants, and use thereof
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation
BR112016020393B1 (pt) 2014-03-05 2022-03-29 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Umidificador para umidificar um aerossol
EP3106090A1 (en) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. System for effective breath-synchronized delivery of medicament to the lungs
US20180110948A1 (en) 2015-04-22 2018-04-26 Chiesi Farmaceutici S.P.A Method and system for effective breath-synchronized delivery of medicament to the lungs
WO2016173634A1 (en) 2015-04-28 2016-11-03 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
WO2016174269A1 (en) 2015-04-30 2016-11-03 University Of Bremen A novel skin medical and cosmetic care product
WO2018019719A1 (en) 2016-07-28 2018-02-01 Chiesi Farmaceutici S.P.A Method and system for delivery of an aerosolized medicament
WO2018077623A1 (en) 2016-10-26 2018-05-03 Chiesi Farmaceutici S.P.A. Device for facilitating the administration of a medicament to the lung by a catheter
CN110099695B (zh) 2016-12-22 2022-01-25 奇斯药制品公司 用于治疗进展性bpd的包含肺表面活性物质和类固醇的治疗组合
CN107163148A (zh) * 2017-05-15 2017-09-15 重庆理工大学 肺表面活性蛋白b前肽的重组蛋白及其制备方法和应用
TW201927286A (zh) 2017-12-15 2019-07-16 義大利商凱西製藥公司 用於噴霧投藥之包含肺表面張力素的藥學調配物
WO2019115771A1 (en) 2017-12-15 2019-06-20 Pari Pharma Gmbh Nebuliser system, holding system, combination comprising nebuliser system and holding system, and aerosol administration method
MX2020011127A (es) 2018-04-23 2021-01-15 Chiesi Farm Spa Combinacion terapeutica que comprende agente tensioactivo pulmonar y esteroide para la profilaxis de displasia broncopulmonar (bpd).
CN109001466A (zh) * 2018-07-19 2018-12-14 新疆维吾尔自治区人民医院 一种用于osa的肺表面活性蛋白试剂盒及其应用
EP3666316A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3666315A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3843105A1 (en) 2019-12-23 2021-06-30 PARI Pharma GmbH Control device for aerosol nebulizer system
WO2021151853A1 (en) 2020-01-28 2021-08-05 Chiesi Farmaceutici S.P.A. Polypeptides having improved properties

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
US5104853A (en) * 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
EP0383837B1 (en) * 1987-11-04 1998-02-04 Byk Gulden Lomberg Chemische Fabrik GmbH Alveolar surfactant proteins
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE3921954A1 (de) * 1989-07-04 1991-01-17 Thomae Gmbh Dr K Niedrig-viskose, hochkonzentrierte surfactant-suspension
JPH05294996A (ja) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤

Also Published As

Publication number Publication date
HUT76952A (hu) 1998-01-28
BG63210B1 (bg) 2001-06-29
KR970703367A (ko) 1997-07-03
BR9507811B1 (pt) 2009-05-05
PL181234B1 (pl) 2001-06-29
SK152496A3 (en) 1997-06-04
DK0764172T3 (da) 2005-01-10
EE9600175A (et) 1997-06-16
NO965052D0 (no) 1996-11-27
JPH10504025A (ja) 1998-04-14
SK282441B6 (sk) 2002-02-05
EP0764172B1 (de) 2004-09-01
US5874406A (en) 1999-02-23
BG101028A (en) 1998-01-30
AU2616995A (en) 1995-12-21
RO118752B1 (ro) 2003-10-30
FI118126B (fi) 2007-07-13
MX9605986A (es) 1998-06-30
AU690280B2 (en) 1998-04-23
NO965052L (no) 1997-01-28
CZ286976B6 (en) 2000-08-16
CY2552B1 (en) 2008-07-02
DE59510941D1 (de) 2004-10-07
CZ350296A3 (en) 1997-05-14
SI0764172T1 (en) 2005-02-28
EP0764172A1 (de) 1997-03-26
ES2227548T3 (es) 2005-04-01
DE4418936A1 (de) 1996-02-08
RU2145611C1 (ru) 2000-02-20
CN1154117A (zh) 1997-07-09
FI964766A0 (fi) 1996-11-29
CA2191344C (en) 2003-04-08
KR100355626B1 (ko) 2002-12-26
HU220191B (hu) 2001-11-28
FI964766A (fi) 1996-11-29
PL317420A1 (en) 1997-04-14
EE03775B1 (et) 2002-06-17
PT764172E (pt) 2005-01-31
UA35636C2 (uk) 2001-04-16
WO1995032992A1 (de) 1995-12-07
CN1130374C (zh) 2003-12-10
ATE275154T1 (de) 2004-09-15
CA2191344A1 (en) 1995-12-07
NZ287447A (en) 1998-01-26
JP3359638B2 (ja) 2002-12-24
NO317149B1 (no) 2004-08-30
HU9603249D0 (en) 1997-01-28
HK1000891A1 (en) 2004-09-17

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Legal Events

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B25D Requested change of name of applicant approved
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: O REQUERENTE DEVERA COMPLEMENTAR A TAXA RELATIVA A 1 REVINDICACAO EXEDENTE. O PEDIDO DE EXAME ( FOLHA 52 ) REFERE-SE A 11 REVINDICACOES, POREM O REQUERENTE DEPOSITOU 12 REVINDICACOES ( FOLHAS 136 E138 ).

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: NYCOMED GMBH (DE)

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B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B22O Other matters related to patents and certificates of addition of invention: legal action concerning patent

Free format text: INPI-52400.061558/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO0132272-32.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: NYCOMED GMBH, OKLAHOMA STATE UNIVERSITY, REGESTS OF THE UNIVERSITY OF MINNESOTA, OTSUKA PHARMACEUTICAL CO LTD, PLASMASEAL CORPORATION

B21B Extinction acc. art. 78, item ii - on waiver by the patentee, without prejudice to the rights of third parties

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B15G Petition not considered as such [chapter 15.7 patent gazette]

Free format text: A PETICAO DE NO 20130064421, APRESENTADA EM 23/07/2013, EM VIRTUDE DO DISPOSTO NOS ARTS. 218 OU 219 DA LPI (LEI 9279 / 96) DE 14/05/1996, E CONSIDERADA COMO PETICAO NAO CONHECIDA EM VIRTUDE DA EXTINCAO DA PATENTE PUBLICADA NA RPI NO 2241, DE 17/12/2013.

B19A Notification of judicial decision: notification of judicial decision

Free format text: INPI-52400.061558/2013-85 13A VARA FEDERAL DO RIO DE JANEIRO ORDINARIA / PROPRIEDADE INDUSTRIAL PROCESSO : 0132272-32.2013.4.02.5101 (2013.51.01.132272-3) AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL INPI REU: REGENTS OF THE UNIVERSITY OF MINNESOTA, OKLAHOMA STATE UNIVERSITY, OTSUKA PHARMACEUTICAL CO. LTD., PLASMASEAL CORPORATION E NYCOMED GMBH. DECISAO: HOMOLOGO, POR SENTENCA, PARA QUE SE PRODUZA OS SEUS JURIDICOS E LEGAIS EFEITOS, OS ACORDOS FIRMADOS ENTRE O INPI E AS RES, CONFORME FLS. 87/89, 93/96, 138/139, 192/193 E 245, JULGANDO EXTINTO O PROCESSO, COM RESOLUCAO DO MERITO, NOS MOLDES DO ARTIGO 269, III DO CODIGO DO PROCESSO CIVIL, EM RELACAO AS ALUDIDAS EMPRESAS RES E AO

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