DE69214467D1 - Verwendung von Thiazolidin-4-carboxylatderivaten zur Behandlung von Lungenerkrankungen - Google Patents

Verwendung von Thiazolidin-4-carboxylatderivaten zur Behandlung von Lungenerkrankungen

Info

Publication number
DE69214467D1
DE69214467D1 DE69214467T DE69214467T DE69214467D1 DE 69214467 D1 DE69214467 D1 DE 69214467D1 DE 69214467 T DE69214467 T DE 69214467T DE 69214467 T DE69214467 T DE 69214467T DE 69214467 D1 DE69214467 D1 DE 69214467D1
Authority
DE
Germany
Prior art keywords
treatment
thiazolidine
lung diseases
carboxylate derivatives
carboxylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69214467T
Other languages
English (en)
Other versions
DE69214467T2 (de
DE69214467T3 (de
Inventor
Dennis I Goldberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transcend Therapeutics Inc
Original Assignee
Transcend Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24563439&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69214467(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Transcend Therapeutics Inc filed Critical Transcend Therapeutics Inc
Application granted granted Critical
Publication of DE69214467D1 publication Critical patent/DE69214467D1/de
Publication of DE69214467T2 publication Critical patent/DE69214467T2/de
Publication of DE69214467T3 publication Critical patent/DE69214467T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69214467T 1991-01-10 1992-01-01 Verwendung von L-2-oxo Thiazolidin-4-carboxylat zur Behandlung von Atemnotsyndrom Expired - Fee Related DE69214467T3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63927591A 1991-01-10 1991-01-10

Publications (3)

Publication Number Publication Date
DE69214467D1 true DE69214467D1 (de) 1996-11-21
DE69214467T2 DE69214467T2 (de) 1997-04-30
DE69214467T3 DE69214467T3 (de) 2000-09-28

Family

ID=24563439

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69214467T Expired - Fee Related DE69214467T3 (de) 1991-01-10 1992-01-01 Verwendung von L-2-oxo Thiazolidin-4-carboxylat zur Behandlung von Atemnotsyndrom

Country Status (10)

Country Link
US (1) US5824693A (de)
EP (2) EP0715853A1 (de)
JP (2) JP2969236B2 (de)
AT (1) ATE144142T1 (de)
AU (2) AU1006492A (de)
CA (1) CA2058793A1 (de)
DE (1) DE69214467T3 (de)
DK (1) DK0494405T3 (de)
ES (1) ES2092539T3 (de)
GR (1) GR3021890T3 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631234A (en) * 1991-04-15 1997-05-20 Teijin Limited Method for treating ischemia-reperfusion tissue injury
FR2763845B1 (fr) 1997-05-30 2003-04-18 Centre Nat Rech Scient Produits anti-cancereux pour le traitement de la mucoviscidose
US6197749B1 (en) 1997-10-29 2001-03-06 Ajinomoto Co., Inc. Method of suppressing immune responses by reducing intracellular content of glutathione in macrophages and monocytes
EP1004302A3 (de) * 1998-10-29 2003-06-04 Ajinomoto Co., Inc. Immunomodulator
AU6676100A (en) 1999-08-17 2001-03-13 University Of Saskatchewan Technologies Inc. Improved treatment for acute physical insult to the central nervous system
US7179791B2 (en) * 2001-01-11 2007-02-20 Duke University Inhibiting GS-FDH to modulate NO bioactivity
KR100478536B1 (ko) * 2002-10-14 2005-03-24 주식회사 에이.비.아이 Ｌ-2-옥소씨아졸리딘-4-카르복실산 또는 그 염을유효성분으로 함유하는 천식 치료용 약제학적 조성물
US20040229815A1 (en) * 2003-01-03 2004-11-18 Nagasawa Herbert T. Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug
US8283435B2 (en) 2003-02-21 2012-10-09 Metabolix, Inc. PHA adhesive compositions
ES2371069T3 (es) 2003-02-21 2011-12-27 Metabolix, Inc. Mezclas de pha.
CA2550009C (en) * 2003-12-30 2013-05-14 Metabolix, Inc. Nucleating agents
CA2620123C (en) * 2005-08-24 2011-11-22 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating and monitoring inflammation and redox imbalance in cystic fibrosis
US20090192227A1 (en) * 2005-08-24 2009-07-30 Rabindra Tirouvanziam N-Acetylcysteine Compositions and Methods for Treating Acute Exacerbations of Inflammatory Lung Disease
US7526715B2 (en) 2005-10-17 2009-04-28 Ramot At Tel Aviv University Ltd. Probabilistic error correction in multi-bit-per-cell flash memory
US20070255406A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for bilateral approach to disc augmentation
US9475930B2 (en) 2012-08-17 2016-10-25 Metabolix, Inc. Biobased rubber modifiers for polymer blends
CA2925546C (en) 2012-10-29 2022-06-14 The University Of North Carolina At Chapel Hill Methods and compositions for treating mucosal tissue disorders
US20140234397A1 (en) * 2013-02-15 2014-08-21 Lou Ann Brown Treatment of klebsiella pneumoniae with liposomally formulated glutathione
WO2014194220A1 (en) 2013-05-30 2014-12-04 Metabolix, Inc. Recyclate blends
CN110198728A (zh) 2016-11-17 2019-09-03 莱诺翁股份有限公司 用谷胱甘肽组合物治疗呼吸道疾病和感染
KR20200089702A (ko) 2017-11-17 2020-07-27 레노비온, 아이엔씨. 안정한 아스코르빈산 조성물 및 그의 사용 방법
CN113797230A (zh) * 2020-06-12 2021-12-17 上海萨美细胞技术有限公司 无细胞脂肪提取液对肺部疾病的治疗用途

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2712202A (en) * 1954-06-08 1955-07-05 Univ Alabama Method of treating tree diseases
DE1767335A1 (de) * 1968-04-27 1971-09-02 Bayer Ag Anaesthetikum fuer Tiere
US3755578A (en) * 1969-06-06 1973-08-28 Pfizer Thiazoline and 5,6-dihydro-4h-1,3-thiazine anti-plant-viral agents
DE2141765A1 (de) * 1971-08-20 1973-03-01 Henkel & Cie Gmbh 4-chlor-4-thiazolin-2-one und verfahren zu deren herstellung
FR2296428A1 (fr) * 1975-01-03 1976-07-30 Baignes Ste Radegonde Laiterie Composition de proteines a usage dietetique et therapeutique chez le nourrisson, l'enfant et l'adulte
JPS53119866A (en) * 1977-03-25 1978-10-19 Yoshitomi Pharmaceut Ind Ltd 5-aryloxy-oxazoleakanoic acid derivatives and their preparation
DE2862059D1 (en) * 1977-12-29 1982-11-11 Synthelabo Thiazolidinedione-2,4 derivatives, their preparation and pharmaceutical applications
US4384001A (en) * 1978-12-21 1983-05-17 Gosalvez Mario Treatment of tumors with thiazolidine-4-carboxylic acid
US4338315A (en) * 1979-11-14 1982-07-06 Eli Lilly And Company Antiviral method employing thiazinyl benzimidazole derivatives
US4434158A (en) * 1981-02-11 1984-02-28 Cornell Research Foundation Cysteine delivery system
US4335210A (en) * 1981-02-11 1982-06-15 Cornell Research Foundation Method of producing L-cysteine
US4647571A (en) * 1981-02-11 1987-03-03 Cornell Research Foundation Cysteine delivery composition
US4438124A (en) * 1981-02-11 1984-03-20 Cornell Research Foundation, Inc. Cysteine delivery system
US4665082A (en) * 1981-02-11 1987-05-12 Cornell Research Foundation Cysteine delivery system
JPS57200373A (en) * 1981-06-04 1982-12-08 Taisho Pharmaceut Co Ltd Thiazolidine derivative
US4420479A (en) * 1982-04-08 1983-12-13 Eli Lilly And Company Olefinic benzimidazoles, formulations, and antiviral methods
DE3317000C2 (de) * 1983-05-10 1986-09-25 Gödecke AG, 1000 Berlin 4-Oxo-thiazolidin-2-yliden-acetamid-derivate, Verfahren zu deren Herstellung und deren Verwendung bei der Bekämpfung von durch das Zentralnervensystem bedingten Konvulsionen
US4879370A (en) * 1983-12-02 1989-11-07 Cornell Research Foundation, Inc. Glutathione delivery system
US4752618A (en) * 1984-07-12 1988-06-21 New England Deaconess Hospital Method of minimizing efects of infection through diet
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
US4710489A (en) * 1985-04-22 1987-12-01 Cornell Research Foundation, Inc. Glutathione delivery system
HU200177B (en) * 1985-06-18 1990-04-28 Biogal Gyogyszergyar Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds
DE3683583D1 (de) * 1985-09-10 1992-03-05 Res Corp Technologies Inc Osmotische mittel fuer peritonealdialyse.
US4780475A (en) * 1986-02-03 1988-10-25 Cerra Frank B Preparation for the prevention of catabolism
JPS63152325A (ja) * 1986-08-20 1988-06-24 Yamanouchi Pharmaceut Co Ltd 脳虚血症予防治療剤
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
US5053387A (en) * 1987-02-20 1991-10-01 Shriners Hospitals For Crippled Children Omega-3 fatty acids in traumatic injury treatment
US4868114A (en) * 1987-08-05 1989-09-19 Regents Of The University Of Minnesota Method for elevating glutathione levels
DE3856378T2 (de) * 1987-09-04 2000-05-11 Beecham Group Plc Substituierte Thiazolidindionderivate
US4968671A (en) * 1987-11-26 1990-11-06 Yamanouchi Pharmaceutical Co., Ltd. Therapeutic agents for ischemic heart diseases
US4791125A (en) * 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
US4798835A (en) * 1987-12-02 1989-01-17 Pfizer Inc. dl-5-[(2-benzyl-3,4-dihydro-2H-benzopyran-6-yl)methyl]thiazolidine-2,4-dione as an anti-atherosclerosis agent
ATE110954T1 (de) * 1988-01-29 1994-09-15 Peter H Proctor Haarwachstumanregung mit nitroxyd und anderen radikalen.
IE891173L (en) * 1988-04-18 1989-10-18 Univ Utrecht Composition for promoting hair growth in androgenetic¹alopecia and method thereof
DE3816603A1 (de) * 1988-05-16 1989-11-30 Behringwerke Ag Verwendung des thiazol-derivates tiprotimod zur herstellung eines mittels zur therapie von virusinfektionen
US5055446A (en) * 1988-10-21 1991-10-08 University Of Cincinnati Method to improve survival of patients during sepsis by diet composition
EP0373002B1 (de) * 1988-12-09 1995-03-01 Allergan, Inc Verwendung von 2-substituierten Thiazolidin-4-carbonsäuren zur Behandlung von Katarakt
CA1338682C (en) * 1988-12-23 1996-10-29 Gustavo Bounous Biologically active undenatured whey protein concentrate as food supplement
GB8918709D0 (en) * 1989-08-16 1989-09-27 Unilever Plc Cosmetic composition
US5158883A (en) * 1989-09-13 1992-10-27 Cornell Research Foundation, Inc. Method of using aminoarginine to block nitric oxide formation in vitro
US5028627A (en) * 1989-09-13 1991-07-02 Cornell Research Foundation, Inc. Method of using arginine derivatives to inhibit systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor
AU7675891A (en) * 1990-03-28 1991-10-21 Atif M Hussein Methods for protecting against chemotherapy-induced hair loss
US5089268A (en) * 1990-05-02 1992-02-18 Katz David P Egg phosphatide lipid emulsions altered for a specific therapeutic fatty acid composition
US5095027A (en) * 1991-02-28 1992-03-10 Clintec Nutrition Co. Method for treating reperfusion injury employing L-2-oxothiazolidine-4-carboxylic acid
SE9103572D0 (sv) * 1991-11-29 1991-11-29 Astra Ab Organic salts of n,n'-diacetyl cystine
US5214062A (en) * 1992-04-08 1993-05-25 Clintec Nutrition Co. Method and composition for treating immune disorders, inflammation and chronic infections
US5208249A (en) * 1992-08-20 1993-05-04 Clintec Nutrition Co. Method for stimulating intracellular synthesis of glutathione using esters of L-2-oxothiazolidine-4-carboxylate

Also Published As

Publication number Publication date
EP0494405A2 (de) 1992-07-15
EP0494405B2 (de) 2000-04-19
AU688803B2 (en) 1998-03-19
CA2058793A1 (en) 1992-07-11
EP0494405A3 (en) 1992-10-28
EP0494405B1 (de) 1996-10-16
US5824693A (en) 1998-10-20
DE69214467T2 (de) 1997-04-30
ATE144142T1 (de) 1996-11-15
DE69214467T3 (de) 2000-09-28
DK0494405T3 (da) 1996-11-18
GR3021890T3 (en) 1997-03-31
ES2092539T3 (es) 1996-12-01
JPH08319242A (ja) 1996-12-03
EP0715853A1 (de) 1996-06-12
AU7912194A (en) 1995-02-16
JPH1053523A (ja) 1998-02-24
JP2969236B2 (ja) 1999-11-02
AU1006492A (en) 1992-07-16

Similar Documents

Publication Publication Date Title
DE69214467D1 (de) Verwendung von Thiazolidin-4-carboxylatderivaten zur Behandlung von Lungenerkrankungen
DE3855113D1 (de) Verwendung von Buspiron zur Herstellung eines pharmazeutischen Präparats zur Behandlung der Alkoholsucht
DE3876877D1 (de) Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus.
DE69334317D1 (de) Gereinigte DNAse Formen
ATE86491T1 (de) Verwendung von fluticasonpropionat zur herstellung eines praeparats zur behandlung von darmerkrankungen.
DE69132688D1 (de) Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
ATE120644T1 (de) Verwendung von 1,3-oxathiolanalogen von nukleosiden zur herstellung eines arzneimittels zur behandlung von hepatitis-b.
ATE73331T1 (de) Verwendung von tetrahydrobiopterinen zur herstellung eines medikaments zur behandlung von kinderautismus.
ATE182593T1 (de) Chemische verbindungen mit pde-iv inhibitierende wirkung
DK0416951T3 (da) Lægemidler indeholdende salmeterol og fluticason
DE59310327D1 (de) Verwendung von Komplement-Inhibitoren zur Herstellung eines Arzneimittels zur Prophylaxe und Therapie von entzündlichen Darm- und Hauterkrankungen sowie Purpura
ATE92762T1 (de) Medikamente.
ATE143260T1 (de) Verwendung von (s)-isofluran und (s)-desfluran zur anästhesie sowie entsprechende arzneimittelzubereitungen
DE69326849D1 (de) Verwendung von humanem Atrio-natriuretischem Peptid zur Herstellung eines Medikaments zur Behandlung des Atemunwohlseinsyndroms bei Erwachsenen
DE3850154D1 (de) Verwendung von Gepiron zur Herstellung eines pharmazeutischen Präparats zur Behandlung atypischer Depression.
ATE162076T1 (de) Verwendung von nadh und nadph zur herstellung eines arzneimittels zur behandlung von morbus alzheimer
NO922635D0 (no) Ny anvendelse av benzimidazolin-2-okso-1-karboksylsyrederivater
SU1577794A1 (ru) Способ лечени ложного крупа у детей
ATE58831T1 (de) Verwendung von dicarbonsaeuren mit 7-13 kohlenstoffatomen oder physiologisch vertraeglichen salzen davon zur herstellung eines arzneimittels zur topischen behandlung von rosazea.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8339 Ceased/non-payment of the annual fee