SK282168B6 - Aminometyl-2,3,8,9-tetrahydro-7h-1,4-dioxín[2,3-e]indol-8-óny a ich použitie - Google Patents
Aminometyl-2,3,8,9-tetrahydro-7h-1,4-dioxín[2,3-e]indol-8-óny a ich použitie Download PDFInfo
- Publication number
- SK282168B6 SK282168B6 SK1414-96A SK141496A SK282168B6 SK 282168 B6 SK282168 B6 SK 282168B6 SK 141496 A SK141496 A SK 141496A SK 282168 B6 SK282168 B6 SK 282168B6
- Authority
- SK
- Slovakia
- Prior art keywords
- tetrahydro
- indol
- dioxin
- methyl
- dioxine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US728395P | 1995-11-06 | 1995-11-06 | |
US08/730,267 US5756532A (en) | 1995-11-06 | 1996-10-15 | Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
SK141496A3 SK141496A3 (en) | 1997-08-06 |
SK282168B6 true SK282168B6 (sk) | 2001-11-06 |
Family
ID=26676776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK1414-96A SK282168B6 (sk) | 1995-11-06 | 1996-10-31 | Aminometyl-2,3,8,9-tetrahydro-7h-1,4-dioxín[2,3-e]indol-8-óny a ich použitie |
Country Status (21)
Country | Link |
---|---|
US (2) | US5756532A (es) |
EP (3) | EP0771800A3 (es) |
JP (1) | JP4311770B2 (es) |
KR (1) | KR100566678B1 (es) |
CN (1) | CN1084748C (es) |
AR (2) | AR004284A1 (es) |
AT (1) | ATE349450T1 (es) |
AU (1) | AU701624B2 (es) |
CA (1) | CA2189524C (es) |
CZ (1) | CZ291731B6 (es) |
DE (1) | DE69636801T2 (es) |
DK (1) | DK1375503T3 (es) |
ES (1) | ES2277014T3 (es) |
HU (1) | HU224841B1 (es) |
IL (1) | IL119565A (es) |
MX (1) | MX9605367A (es) |
NO (1) | NO317054B1 (es) |
NZ (1) | NZ299693A (es) |
PT (1) | PT1375503E (es) |
RU (1) | RU2178416C2 (es) |
SK (1) | SK282168B6 (es) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9627005D0 (en) * | 1996-12-27 | 1997-02-12 | Knoll Ag | Therapeutic agents |
GB9704948D0 (en) | 1997-03-11 | 1997-04-30 | Knoll Ag | Therapeutic agents |
US6362009B1 (en) | 1997-11-21 | 2002-03-26 | Merck & Co., Inc. | Solid phase synthesis of heterocycles |
US6350773B1 (en) * | 1999-12-10 | 2002-02-26 | American Home Products Corporation | Therapeutic combinations of (S)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro 7H-1,4-dioxino{2,3-e}indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders |
AR026756A1 (es) * | 1999-12-10 | 2003-02-26 | Wyeth Corp | Nuevas combinaciones terapeuticas (s)-2-bencilamino-metil)-2,3,8,9-tetrahidro-7h-1,4-dioxino[2,3-e]indol-8-ona y neuroleticos para el tratamiento oprevencion de desordenes psicoticos |
US20060287335A1 (en) * | 2000-11-28 | 2006-12-21 | Wyeth | Serotonergic agents for treating sexual dysfunction |
US20060223824A1 (en) * | 2000-11-28 | 2006-10-05 | Wyeth | Serotonergic agents |
US6458802B1 (en) | 2001-03-14 | 2002-10-01 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline |
US6803368B2 (en) | 2001-04-25 | 2004-10-12 | Wyeth | Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene |
US6800648B2 (en) | 2001-04-26 | 2004-10-05 | Wyeth | Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one |
US6800641B2 (en) | 2001-04-26 | 2004-10-05 | Wyeth | Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-2,3-diaza-cyclopenta[a]naphthalene |
US6861427B2 (en) * | 2001-04-26 | 2005-03-01 | Wyeth | Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists |
US6800642B2 (en) | 2001-04-26 | 2004-10-05 | Wyeth | Antipsychotic aminomethyl derivatives of 7,8-dihydro-2,6,9-trioxa-3-aza-cyclopenta[a]naphthalene |
US6927226B2 (en) | 2001-04-26 | 2005-08-09 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene |
US6861434B2 (en) | 2001-04-26 | 2005-03-01 | Wyeth | Antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one |
WO2002088132A1 (en) | 2001-04-26 | 2002-11-07 | Wyeth | Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-ht1aantagonists |
EP1381612A1 (en) | 2001-04-26 | 2004-01-21 | Wyeth | Antidepressant aza-heterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinazoline |
US7008944B2 (en) * | 2001-04-26 | 2006-03-07 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-Dioxino[2,3-f]quinoxaline |
CA2445581A1 (en) | 2001-04-26 | 2002-11-07 | Jonathan Laird Gross | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoxaline |
WO2002088131A1 (en) * | 2001-04-26 | 2002-11-07 | Wyeth | Antidepressant (sssri) azaheterocyclymethyl derivatives of 7,8-dihydro-3h-t,9-dioxa-1,3-diazacyclopenta[a]naphthalene |
US6906206B2 (en) | 2001-04-30 | 2005-06-14 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene |
US6555560B2 (en) * | 2001-04-30 | 2003-04-29 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene |
WO2002092602A2 (en) * | 2001-05-17 | 2002-11-21 | Wyeth | PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-[2,3-f] QUINOLINE |
US6541502B1 (en) | 2001-07-20 | 2003-04-01 | Wyeth | 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity |
US6541501B2 (en) | 2001-07-20 | 2003-04-01 | Wyeth | 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity |
US6903110B2 (en) * | 2001-07-25 | 2005-06-07 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene |
US6800637B2 (en) * | 2002-09-12 | 2004-10-05 | Wyeth | Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines |
CN100352820C (zh) * | 2002-09-12 | 2007-12-05 | 惠氏公司 | 抗抑郁的杂环稠合的苯并二噁烷的氮杂环甲基衍生物 |
US7153849B2 (en) * | 2002-09-12 | 2006-12-26 | Wyeth | Antidepressant arylpiperazine derivatives of hetrocycle-fused benzodioxans |
US6939877B2 (en) * | 2002-09-12 | 2005-09-06 | Wyeth | Antidepressant piperidine derivatives of heterocycle-fused benzodioxans |
US7135479B2 (en) | 2002-09-12 | 2006-11-14 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans |
SG147450A1 (en) | 2003-10-29 | 2008-11-28 | Wyeth Corp | Sustained release pharmaceutical compositions comprising aplindore and derivatives thereof |
BRPI0608353A2 (pt) | 2005-02-17 | 2009-12-01 | Wyeth Corp | derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos |
CA2599588A1 (en) * | 2005-03-01 | 2006-09-08 | Wyeth | Crystalline and amorphous 4-cyano-n{(2r)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-n-pyridin-2-yl-benzamide hydrochloride |
CA2604915A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | New therapeutic combinations for the treatment or prevention of depression |
TW200811182A (en) * | 2006-05-25 | 2008-03-01 | Wyeth Corp | Oxindoledioxans, synthesis thereof, and intermediates thereto |
WO2008118935A1 (en) * | 2007-03-26 | 2008-10-02 | Neurogen Corporation | Compounds and processes for preparing substituted aminomethyl-2,3,8,9-tetrahydro-7h-1,4-dioxino[2,3-e]indol-8-ones |
AU2010232750B2 (en) * | 2009-03-30 | 2015-10-29 | Vtv Therapeutics Llc | Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof |
RU2554883C1 (ru) * | 2014-05-27 | 2015-06-27 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) | Применение производных ацеталей пиридоксина в качестве антагонистов пуринорецепторов |
RU2554885C1 (ru) * | 2014-05-27 | 2015-06-27 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) | Антагонисты пуринорецепторов на основе новых производных пиридоксина |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991013872A1 (en) * | 1990-03-15 | 1991-09-19 | The Upjohn Company | Therapeutically useful heterocyclic indole compounds |
US5166367A (en) * | 1991-06-21 | 1992-11-24 | American Home Products Corporation | Antipsychotic benzodioxan derivatives |
US5126366A (en) * | 1991-06-21 | 1992-06-30 | American Home Products Corporation | Aminophenoxyalkyl derivatives of benzodioxan |
US5189171A (en) * | 1991-06-21 | 1993-02-23 | American Home Products Corporation | Antipsychotic benzodioxan derivatives |
DE4135474A1 (de) * | 1991-10-28 | 1993-04-29 | Bayer Ag | 2-aminomethyl-chromane |
US5235055A (en) * | 1992-09-02 | 1993-08-10 | American Home Products Corporation | Antipsychotic quinoline derivatives of benzodioxanmethylamine |
US5245051A (en) * | 1992-09-03 | 1993-09-14 | American Home Products Corporation | Antipsychotic chroman derivatives of benzodioxanmethylamine |
-
1996
- 1996-10-15 US US08/730,267 patent/US5756532A/en not_active Expired - Lifetime
- 1996-10-22 AT AT03021780T patent/ATE349450T1/de active
- 1996-10-22 EP EP96307616A patent/EP0771800A3/en not_active Ceased
- 1996-10-22 EP EP03021780A patent/EP1375503B1/en not_active Expired - Lifetime
- 1996-10-22 PT PT03021780T patent/PT1375503E/pt unknown
- 1996-10-22 ES ES03021780T patent/ES2277014T3/es not_active Expired - Lifetime
- 1996-10-22 EP EP06015712A patent/EP1726592A1/en not_active Withdrawn
- 1996-10-22 DE DE69636801T patent/DE69636801T2/de not_active Expired - Lifetime
- 1996-10-22 DK DK03021780T patent/DK1375503T3/da active
- 1996-10-31 SK SK1414-96A patent/SK282168B6/sk not_active IP Right Cessation
- 1996-11-01 AU AU70553/96A patent/AU701624B2/en not_active Ceased
- 1996-11-04 NZ NZ299693A patent/NZ299693A/xx not_active IP Right Cessation
- 1996-11-04 CA CA002189524A patent/CA2189524C/en not_active Expired - Fee Related
- 1996-11-04 RU RU96121824/04A patent/RU2178416C2/ru not_active IP Right Cessation
- 1996-11-05 IL IL11956596A patent/IL119565A/en not_active IP Right Cessation
- 1996-11-05 NO NO19964686A patent/NO317054B1/no not_active IP Right Cessation
- 1996-11-05 JP JP29247996A patent/JP4311770B2/ja not_active Expired - Fee Related
- 1996-11-05 MX MX9605367A patent/MX9605367A/es unknown
- 1996-11-05 HU HU9603057A patent/HU224841B1/hu not_active IP Right Cessation
- 1996-11-05 CZ CZ19963241A patent/CZ291731B6/cs not_active IP Right Cessation
- 1996-11-05 KR KR1019960051969A patent/KR100566678B1/ko not_active IP Right Cessation
- 1996-11-05 CN CN96121650A patent/CN1084748C/zh not_active Expired - Fee Related
- 1996-11-05 AR ARP960105059A patent/AR004284A1/es active IP Right Grant
-
1998
- 1998-01-29 US US09/015,149 patent/US5962465A/en not_active Expired - Lifetime
-
2000
- 2000-09-15 AR ARP000104875A patent/AR025698A1/es unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20141031 |