SK281390B6 - 2,3,4,5-tetrahydro-1h-benzazepíny, spôsob ich prípravy, farmaceutický prostriedok a použitie - Google Patents

2,3,4,5-tetrahydro-1h-benzazepíny, spôsob ich prípravy, farmaceutický prostriedok a použitie Download PDF

Info

Publication number
SK281390B6
SK281390B6 SK1000-94A SK100094A SK281390B6 SK 281390 B6 SK281390 B6 SK 281390B6 SK 100094 A SK100094 A SK 100094A SK 281390 B6 SK281390 B6 SK 281390B6
Authority
SK
Slovakia
Prior art keywords
compound
formula
tetrahydro
chloro
benzazepine
Prior art date
Application number
SK1000-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK100094A3 (en
Inventor
Christian Foged
Rolf Hohlweg
Erik Bardrum Nielsen
Original Assignee
Cenes Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cenes Limited filed Critical Cenes Limited
Publication of SK100094A3 publication Critical patent/SK100094A3/sk
Publication of SK281390B6 publication Critical patent/SK281390B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK1000-94A 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-benzazepíny, spôsob ich prípravy, farmaceutický prostriedok a použitie SK281390B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK92233A DK23392D0 (da) 1992-02-24 1992-02-24 Heterocykliske forbindelser, deres anvendelse og fremstilling
PCT/DK1993/000041 WO1993017012A1 (en) 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-3-benzazepines and pharmaceutically acceptable acid addition salts thereof

Publications (2)

Publication Number Publication Date
SK100094A3 SK100094A3 (en) 1995-04-12
SK281390B6 true SK281390B6 (sk) 2001-03-12

Family

ID=8091236

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1000-94A SK281390B6 (sk) 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-benzazepíny, spôsob ich prípravy, farmaceutický prostriedok a použitie

Country Status (23)

Country Link
EP (1) EP0628039B1 (xx)
JP (1) JPH07504172A (xx)
KR (1) KR100255739B1 (xx)
AT (1) ATE152450T1 (xx)
AU (1) AU667878B2 (xx)
BG (1) BG62208B1 (xx)
CA (1) CA2130678C (xx)
CZ (1) CZ288626B6 (xx)
DE (1) DE69310353T2 (xx)
DK (2) DK23392D0 (xx)
ES (1) ES2102019T3 (xx)
FI (1) FI113770B (xx)
GR (1) GR3023896T3 (xx)
HU (1) HU221314B1 (xx)
IL (1) IL104657A (xx)
NO (1) NO310193B1 (xx)
NZ (1) NZ249465A (xx)
RO (1) RO116088B1 (xx)
RU (1) RU2114839C1 (xx)
SK (1) SK281390B6 (xx)
UA (1) UA34451C2 (xx)
WO (1) WO1993017012A1 (xx)
ZA (1) ZA931099B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995025102A1 (en) * 1994-03-16 1995-09-21 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
CZ77898A3 (cs) * 1995-09-15 1998-07-15 Cenes Limited Kyselé adiční soli 2,3,4,5-tetrahydro-1H-3-benzazepinových sloučenin
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
MX368959B (es) 2012-10-25 2019-10-23 Tetra Discovery Partners Llc Inhibidores heteroarilo de pde4.
US20150086480A1 (en) * 2013-09-26 2015-03-26 Tetra Discovery Partners, LLC Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater

Also Published As

Publication number Publication date
RU94040719A (ru) 1996-07-10
NO943123D0 (no) 1994-08-24
RO116088B1 (ro) 2000-10-30
UA34451C2 (uk) 2001-03-15
HUT71127A (en) 1995-11-28
CZ288626B6 (cs) 2001-08-15
ES2102019T3 (es) 1997-07-16
HU9402434D0 (en) 1994-10-28
KR950700286A (ko) 1995-01-16
FI113770B (fi) 2004-06-15
IL104657A0 (en) 1993-06-10
EP0628039B1 (en) 1997-05-02
CA2130678A1 (en) 1993-08-25
FI943875A0 (fi) 1994-08-23
CZ198894A3 (en) 1995-10-18
DK23392D0 (da) 1992-02-24
ZA931099B (en) 1994-08-17
BG62208B1 (bg) 1999-05-31
CA2130678C (en) 2004-04-20
NZ249465A (en) 1996-02-27
EP0628039A1 (en) 1994-12-14
DE69310353T2 (de) 1997-10-02
RU2114839C1 (ru) 1998-07-10
FI943875A (fi) 1994-08-23
AU667878B2 (en) 1996-04-18
IL104657A (en) 1999-11-30
SK100094A3 (en) 1995-04-12
NO310193B1 (no) 2001-06-05
GR3023896T3 (en) 1997-09-30
DE69310353D1 (de) 1997-06-05
AU3626593A (en) 1993-09-13
NO943123L (no) 1994-08-24
HU221314B1 (en) 2002-09-28
JPH07504172A (ja) 1995-05-11
DK0628039T3 (da) 1997-12-08
WO1993017012A1 (en) 1993-09-02
BG98993A (bg) 1995-05-31
KR100255739B1 (ko) 2000-05-01
ATE152450T1 (de) 1997-05-15

Similar Documents

Publication Publication Date Title
US7250531B2 (en) Process for the synthesis and crystalline form of agomelatine
DE69303569T2 (de) Arylalkyl(thio)amide mit Melatonin-Rezeptor-Selektivität und Prozess zu ihrer Darstellung
EP1656352A1 (en) 6-(2,2,2-TRIFLUOROETHYLAMINO)-7-CHLORO-2,3,4,5-TETRAHYDRO-1H-BENZO d AZEPINE AS A 5-HT sb 2c /sb RECEPTOR AGONIST
US20080033054A1 (en) Process for preparing memantine hydrochloride substantially free of impurities
DE68914471T2 (de) Thieno[2,3-d]azepinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.
SK281390B6 (sk) 2,3,4,5-tetrahydro-1h-benzazepíny, spôsob ich prípravy, farmaceutický prostriedok a použitie
US5010074A (en) Novel benzazepine derivatives
US5470850A (en) 2,3,4,5-tetrahydro-1H-3-benzazepines
EP0233049A1 (en) 2,3,4,8,9,9a-Hexahydro-4-aryl-1H-indeno[1,7-cd]azepines
JPH02115166A (ja) ピリジルケトオキシムエーテル誘導体
US20090076039A1 (en) Deuterium-enriched valacyclovir
KR100226328B1 (ko) 4-(4-또는6-(트리플루오로메틸-2-피리디닐))-1-피페라지닐알킬치환된락탐
DE69011150T2 (de) Antidopaminergic Benzodiazepine.
US20090062331A1 (en) Deuterium-enriched maraviroc
JPH07121924B2 (ja) チアジアゾールグアニジン類
RU2033414C1 (ru) Производные 4,5,6,7-тетрагидробензимидазола
US20110144174A1 (en) Deuterium-enriched odansetron
JPH07103097B2 (ja) オキシサリチルアミド誘導体
US20090076082A1 (en) Deuterium-enriched alvimopan
US20080299218A1 (en) Deuterium-enriched valsartan
DK163993B (da) 5,7,8-substituerede 2,3,4,5-tetrahydro-1h-3-benzazepiner, fremstilling af disse, samt farmaceutiske praeparater indeholdende disse