SK281341B6 - Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce - Google Patents
Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce Download PDFInfo
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- SK281341B6 SK281341B6 SK1574-96A SK157496A SK281341B6 SK 281341 B6 SK281341 B6 SK 281341B6 SK 157496 A SK157496 A SK 157496A SK 281341 B6 SK281341 B6 SK 281341B6
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- halogen
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- 229920001993 poloxamer 188 Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 239000011698 potassium fluoride Substances 0.000 description 1
- 235000003270 potassium fluoride Nutrition 0.000 description 1
- WSHYKIAQCMIPTB-UHFFFAOYSA-M potassium;2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate Chemical compound [K+].[O-]C=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 WSHYKIAQCMIPTB-UHFFFAOYSA-M 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 229960001309 procaine hydrochloride Drugs 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- YPOXGDJGKBXRFP-UHFFFAOYSA-N pyrimidine-4-carboxylic acid Chemical compound OC(=O)C1=CC=NC=N1 YPOXGDJGKBXRFP-UHFFFAOYSA-N 0.000 description 1
- SBMSLRMNBSMKQC-UHFFFAOYSA-N pyrrolidin-1-amine Chemical compound NN1CCCC1 SBMSLRMNBSMKQC-UHFFFAOYSA-N 0.000 description 1
- NGXSWUFDCSEIOO-UHFFFAOYSA-N pyrrolidin-3-amine Chemical compound NC1CCNC1 NGXSWUFDCSEIOO-UHFFFAOYSA-N 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000012419 sodium bis(2-methoxyethoxy)aluminum hydride Substances 0.000 description 1
- 239000012312 sodium hydride Substances 0.000 description 1
- 229910000104 sodium hydride Inorganic materials 0.000 description 1
- 235000010288 sodium nitrite Nutrition 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
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- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- GZDLAMUIGYXKLH-HZPDHXFCSA-N tert-butyl 2-[[(3r,4r)-1-benzyl-4-methoxypyrrolidin-3-yl]amino]acetate Chemical compound C1[C@@H](NCC(=O)OC(C)(C)C)[C@H](OC)CN1CC1=CC=CC=C1 GZDLAMUIGYXKLH-HZPDHXFCSA-N 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- QRMKWVNXYORDRU-UKRRQHHQSA-N tert-butyl n-[(3s,4r)-1-benzyl-4-methylpyrrolidin-3-yl]carbamate Chemical compound C1[C@@H](NC(=O)OC(C)(C)C)[C@H](C)CN1CC1=CC=CC=C1 QRMKWVNXYORDRU-UKRRQHHQSA-N 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15657894 | 1994-06-14 | ||
| JP19792194 | 1994-07-28 | ||
| JP30691494 | 1994-11-15 | ||
| JP33995694 | 1994-12-28 | ||
| JP8170595 | 1995-03-13 | ||
| PCT/JP1995/001110 WO1995034559A1 (en) | 1994-06-14 | 1995-06-06 | Novel compound, process for producing the same, and antitumor agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK157496A3 SK157496A3 (en) | 1997-08-06 |
| SK281341B6 true SK281341B6 (sk) | 2001-02-12 |
Family
ID=27524935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1574-96A SK281341B6 (sk) | 1994-06-14 | 1995-06-06 | Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5817669A (OSRAM) |
| EP (1) | EP0787726B1 (OSRAM) |
| JP (1) | JP3391796B2 (OSRAM) |
| KR (1) | KR100350921B1 (OSRAM) |
| CN (1) | CN1053668C (OSRAM) |
| AT (1) | ATE209645T1 (OSRAM) |
| AU (1) | AU679859B2 (OSRAM) |
| BR (1) | BR9508037A (OSRAM) |
| CA (1) | CA2192824C (OSRAM) |
| CZ (1) | CZ292631B6 (OSRAM) |
| DE (1) | DE69524251T2 (OSRAM) |
| DK (1) | DK0787726T3 (OSRAM) |
| ES (1) | ES2163512T3 (OSRAM) |
| FI (1) | FI112485B (OSRAM) |
| HK (1) | HK1000495A1 (OSRAM) |
| HU (1) | HU220072B (OSRAM) |
| MX (1) | MX9606331A (OSRAM) |
| NO (1) | NO307255B1 (OSRAM) |
| NZ (1) | NZ287139A (OSRAM) |
| PL (1) | PL181867B1 (OSRAM) |
| PT (1) | PT787726E (OSRAM) |
| RO (1) | RO117793B1 (OSRAM) |
| RU (1) | RU2151770C1 (OSRAM) |
| SI (1) | SI0787726T1 (OSRAM) |
| SK (1) | SK281341B6 (OSRAM) |
| TW (1) | TW319769B (OSRAM) |
| WO (1) | WO1995034559A1 (OSRAM) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20040309A2 (en) | 2001-09-26 | 2006-05-31 | Bayer Pharmaceuticals Corporation | 1,6-nafthyridine derivatives as antidiabetics |
| US6802423B2 (en) * | 2002-02-20 | 2004-10-12 | Trans Global Foods, Inc. | Disposable food delivery apparatus |
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