SK281124B6 - (s)-(-)-2-trifluórmetyl-4-(3-kyanofenyl)-4,6,7,8-tetrahydro- -5(1h)-chinolón, spôsoby jeho prípravy, farmaceutické prostriedky, ktoré ho obsahujú a jeho použitie - Google Patents

(s)-(-)-2-trifluórmetyl-4-(3-kyanofenyl)-4,6,7,8-tetrahydro- -5(1h)-chinolón, spôsoby jeho prípravy, farmaceutické prostriedky, ktoré ho obsahujú a jeho použitie Download PDF

Info

Publication number
SK281124B6
SK281124B6 SK1317-96A SK131796A SK281124B6 SK 281124 B6 SK281124 B6 SK 281124B6 SK 131796 A SK131796 A SK 131796A SK 281124 B6 SK281124 B6 SK 281124B6
Authority
SK
Slovakia
Prior art keywords
compound
formula
trifluoromethyl
acid
cyanophenyl
Prior art date
Application number
SK1317-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK131796A3 (en
Inventor
John Edward Warawa
Cyrus John Ohnmacht Jr.
Diane Amy Trainor
James Michael Hulsizer
Original Assignee
Zeneca Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Limited filed Critical Zeneca Limited
Publication of SK131796A3 publication Critical patent/SK131796A3/sk
Publication of SK281124B6 publication Critical patent/SK281124B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1317-96A 1994-04-14 1995-04-13 (s)-(-)-2-trifluórmetyl-4-(3-kyanofenyl)-4,6,7,8-tetrahydro- -5(1h)-chinolón, spôsoby jeho prípravy, farmaceutické prostriedky, ktoré ho obsahujú a jeho použitie SK281124B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9407432A GB9407432D0 (en) 1994-04-14 1994-04-14 Heterocyclic derivative
PCT/GB1995/000845 WO1995028388A1 (en) 1994-04-14 1995-04-13 Quinolone derivative for treatment of urinary incontinence

Publications (2)

Publication Number Publication Date
SK131796A3 SK131796A3 (en) 1997-05-07
SK281124B6 true SK281124B6 (sk) 2000-12-11

Family

ID=10753541

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1317-96A SK281124B6 (sk) 1994-04-14 1995-04-13 (s)-(-)-2-trifluórmetyl-4-(3-kyanofenyl)-4,6,7,8-tetrahydro- -5(1h)-chinolón, spôsoby jeho prípravy, farmaceutické prostriedky, ktoré ho obsahujú a jeho použitie

Country Status (25)

Country Link
EP (1) EP0755382B1 (ru)
JP (1) JP3782445B2 (ru)
KR (1) KR100344885B1 (ru)
CN (1) CN1058708C (ru)
AT (1) ATE202089T1 (ru)
AU (1) AU700773B2 (ru)
BR (1) BR9507366A (ru)
CA (1) CA2187525C (ru)
CZ (1) CZ284652B6 (ru)
DE (1) DE69521310T2 (ru)
DK (1) DK0755382T3 (ru)
ES (1) ES2159633T3 (ru)
FI (2) FI114705B (ru)
GB (1) GB9407432D0 (ru)
GR (1) GR3036482T3 (ru)
HK (1) HK1013999A1 (ru)
HU (1) HU215387B (ru)
MX (1) MX9603920A (ru)
NO (1) NO307177B1 (ru)
NZ (1) NZ283779A (ru)
PL (2) PL183095B1 (ru)
PT (1) PT755382E (ru)
RU (1) RU2149870C1 (ru)
SK (1) SK281124B6 (ru)
WO (1) WO1995028388A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2292462T3 (es) * 1999-08-03 2008-03-16 Abbott Laboratories Agentes abridores de los canales del potasio.
EP1307429B1 (en) 2000-08-02 2007-11-28 AstraZeneca AB Process for asymmetric synthesis of substituted 1,4-dihydropyridines
SE0200205D0 (sv) 2002-01-24 2002-01-24 Astrazeneca Ab Method
CN102532015B (zh) * 2012-01-18 2013-10-23 云南大学 香豆素及其类似物的固相合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2003148A1 (de) * 1970-01-24 1971-07-29 Bayer Ag Neue 1,4-Dihydropyridinderivate
GB9220570D0 (en) * 1991-10-21 1992-11-11 Ici Plc Therapeutic agent
GB9318935D0 (en) * 1992-10-20 1993-10-27 Zeneca Ltd Heterocyclic derivatives

Also Published As

Publication number Publication date
NO964345D0 (no) 1996-10-11
JPH09512254A (ja) 1997-12-09
WO1995028388A1 (en) 1995-10-26
DK0755382T3 (da) 2001-09-10
NO307177B1 (no) 2000-02-21
HUT76132A (en) 1997-06-30
CZ298196A3 (en) 1997-02-12
RU2149870C1 (ru) 2000-05-27
DE69521310T2 (de) 2002-04-18
AU2219995A (en) 1995-11-10
GB9407432D0 (en) 1994-06-08
HU9602747D0 (en) 1996-11-28
SK131796A3 (en) 1997-05-07
CA2187525A1 (en) 1995-10-26
ES2159633T3 (es) 2001-10-16
HK1013999A1 (en) 1999-09-17
PL182031B1 (pl) 2001-10-31
EP0755382B1 (en) 2001-06-13
NO964345L (no) 1996-12-11
AU700773B2 (en) 1999-01-14
FI964019A (fi) 1996-10-07
PT755382E (pt) 2001-11-30
EP0755382A1 (en) 1997-01-29
FI964019A0 (fi) 1996-10-07
GR3036482T3 (en) 2001-11-30
CN1058708C (zh) 2000-11-22
JP3782445B2 (ja) 2006-06-07
PL183095B1 (pl) 2002-05-31
PL316790A1 (en) 1997-02-17
FI114705B (fi) 2004-12-15
CZ284652B6 (cs) 1999-01-13
BR9507366A (pt) 1997-09-23
HU215387B (hu) 1998-12-28
MX9603920A (es) 1997-04-30
NZ283779A (en) 1998-02-26
DE69521310D1 (de) 2001-07-19
KR100344885B1 (ko) 2002-11-30
FI115630B (fi) 2005-06-15
CA2187525C (en) 2006-01-24
CN1146202A (zh) 1997-03-26
ATE202089T1 (de) 2001-06-15
FI20040352A (fi) 2004-03-04

Similar Documents

Publication Publication Date Title
KR100296657B1 (ko) 요실금치료용퀴놀론및아크리딘온유도체
JP4660045B2 (ja) ＮＦ−κＢ阻害剤を有効成分とする心筋炎、拡張型心筋症および心不全の予防または治療薬
EP0539154B1 (en) Acridine-1,8-dione-derivatives as therapeutic agents
EP0177392A1 (fr) Nouvelles (pyridyl-2)-1 pipérazines, leur procédé de préparation et leur application en thérapeutique
CZ219895A3 (en) The use of substituted derivatives of 4-phenyl-6-aminonicotinic acid as medicaments
EP0625511B1 (en) Heterocyclic compounds and their use in pharmaceutical
US5455253A (en) Heterocyclic derivatives
JP3853389B2 (ja) 新規の３−フェニルスルホニル−３，７−ジアザビシクロ［３，３，１］ノナン−化合物、その製法及び抗不整脈剤
SK281124B6 (sk) (s)-(-)-2-trifluórmetyl-4-(3-kyanofenyl)-4,6,7,8-tetrahydro- -5(1h)-chinolón, spôsoby jeho prípravy, farmaceutické prostriedky, ktoré ho obsahujú a jeho použitie
AU731407B2 (en) Quinolone derivative for treatment of urinary incontinence
CN113651767B (zh) 一种苯并异噁唑类杂环化合物及其制备方法和应用
FR2802532A1 (fr) Derives de 2-phenyl-quinoleine, leur preparation et leur application en therapeutique
CZ20021786A3 (cs) Deriváty 2-arylchinolinu, způsob jejich přípravy a farmaceutické kompozice, které je obsahují

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100413