BR9507366A - Composto composição farmaceutica processos para a preparação de (s)-(-)-2-trifluorometil-4-(3-cianofenil)-4, 6,7,8-tetraidro-5 (1H)- - quinolona, do ácido4-3-cianofenil)2-trifluorometil-5-oxo-1,4,5,6,7,8- -hexaidroquinolina-3-carboxilio, de 4,4,4-trifluoroacetoacetato de isobornila, de 2-cianoetil hemiacetal de 4,4,4- trifluoroacetoatato de 2-cianoetila e para o tratamento da incontinéncia urinária e utilização do composto - Google Patents
Composto composição farmaceutica processos para a preparação de (s)-(-)-2-trifluorometil-4-(3-cianofenil)-4, 6,7,8-tetraidro-5 (1H)- - quinolona, do ácido4-3-cianofenil)2-trifluorometil-5-oxo-1,4,5,6,7,8- -hexaidroquinolina-3-carboxilio, de 4,4,4-trifluoroacetoacetato de isobornila, de 2-cianoetil hemiacetal de 4,4,4- trifluoroacetoatato de 2-cianoetila e para o tratamento da incontinéncia urinária e utilização do compostoInfo
- Publication number
- BR9507366A BR9507366A BR9507366A BR9507366A BR9507366A BR 9507366 A BR9507366 A BR 9507366A BR 9507366 A BR9507366 A BR 9507366A BR 9507366 A BR9507366 A BR 9507366A BR 9507366 A BR9507366 A BR 9507366A
- Authority
- BR
- Brazil
- Prior art keywords
- cyanophenyl
- trifluoromethyl
- cyanoethyl
- compound
- tetrahydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9407432A GB9407432D0 (en) | 1994-04-14 | 1994-04-14 | Heterocyclic derivative |
PCT/GB1995/000845 WO1995028388A1 (en) | 1994-04-14 | 1995-04-13 | Quinolone derivative for treatment of urinary incontinence |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9507366A true BR9507366A (pt) | 1997-09-23 |
Family
ID=10753541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9507366A BR9507366A (pt) | 1994-04-14 | 1995-04-13 | Composto composição farmaceutica processos para a preparação de (s)-(-)-2-trifluorometil-4-(3-cianofenil)-4, 6,7,8-tetraidro-5 (1H)- - quinolona, do ácido4-3-cianofenil)2-trifluorometil-5-oxo-1,4,5,6,7,8- -hexaidroquinolina-3-carboxilio, de 4,4,4-trifluoroacetoacetato de isobornila, de 2-cianoetil hemiacetal de 4,4,4- trifluoroacetoatato de 2-cianoetila e para o tratamento da incontinéncia urinária e utilização do composto |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0755382B1 (pt) |
JP (1) | JP3782445B2 (pt) |
KR (1) | KR100344885B1 (pt) |
CN (1) | CN1058708C (pt) |
AT (1) | ATE202089T1 (pt) |
AU (1) | AU700773B2 (pt) |
BR (1) | BR9507366A (pt) |
CA (1) | CA2187525C (pt) |
CZ (1) | CZ284652B6 (pt) |
DE (1) | DE69521310T2 (pt) |
DK (1) | DK0755382T3 (pt) |
ES (1) | ES2159633T3 (pt) |
FI (2) | FI114705B (pt) |
GB (1) | GB9407432D0 (pt) |
GR (1) | GR3036482T3 (pt) |
HK (1) | HK1013999A1 (pt) |
HU (1) | HU215387B (pt) |
MX (1) | MX9603920A (pt) |
NO (1) | NO307177B1 (pt) |
NZ (1) | NZ283779A (pt) |
PL (2) | PL183095B1 (pt) |
PT (1) | PT755382E (pt) |
RU (1) | RU2149870C1 (pt) |
SK (1) | SK281124B6 (pt) |
WO (1) | WO1995028388A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60036476T2 (de) * | 1999-08-03 | 2008-06-12 | Abbott Laboratories, Abbott Park | Kalium kanalaktivatoren |
EP1307429B1 (en) * | 2000-08-02 | 2007-11-28 | AstraZeneca AB | Process for asymmetric synthesis of substituted 1,4-dihydropyridines |
SE0200205D0 (sv) * | 2002-01-24 | 2002-01-24 | Astrazeneca Ab | Method |
CN102532015B (zh) * | 2012-01-18 | 2013-10-23 | 云南大学 | 香豆素及其类似物的固相合成方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2003148A1 (de) * | 1970-01-24 | 1971-07-29 | Bayer Ag | Neue 1,4-Dihydropyridinderivate |
GB9220570D0 (en) * | 1991-10-21 | 1992-11-11 | Ici Plc | Therapeutic agent |
GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
-
1994
- 1994-04-14 GB GB9407432A patent/GB9407432D0/en active Pending
-
1995
- 1995-04-13 MX MX9603920A patent/MX9603920A/es not_active IP Right Cessation
- 1995-04-13 BR BR9507366A patent/BR9507366A/pt not_active IP Right Cessation
- 1995-04-13 PL PL95343448A patent/PL183095B1/pl not_active IP Right Cessation
- 1995-04-13 EP EP95915256A patent/EP0755382B1/en not_active Expired - Lifetime
- 1995-04-13 CN CN95192577A patent/CN1058708C/zh not_active Expired - Fee Related
- 1995-04-13 RU RU96119966/04A patent/RU2149870C1/ru active
- 1995-04-13 PT PT95915256T patent/PT755382E/pt unknown
- 1995-04-13 KR KR1019960705672A patent/KR100344885B1/ko not_active IP Right Cessation
- 1995-04-13 ES ES95915256T patent/ES2159633T3/es not_active Expired - Lifetime
- 1995-04-13 SK SK1317-96A patent/SK281124B6/sk not_active IP Right Cessation
- 1995-04-13 DE DE69521310T patent/DE69521310T2/de not_active Expired - Fee Related
- 1995-04-13 PL PL95316790A patent/PL182031B1/pl not_active IP Right Cessation
- 1995-04-13 CA CA002187525A patent/CA2187525C/en not_active Expired - Fee Related
- 1995-04-13 NZ NZ283779A patent/NZ283779A/en not_active IP Right Cessation
- 1995-04-13 WO PCT/GB1995/000845 patent/WO1995028388A1/en active IP Right Grant
- 1995-04-13 AT AT95915256T patent/ATE202089T1/de not_active IP Right Cessation
- 1995-04-13 DK DK95915256T patent/DK0755382T3/da active
- 1995-04-13 HU HU9602747A patent/HU215387B/hu not_active IP Right Cessation
- 1995-04-13 CZ CZ962981A patent/CZ284652B6/cs not_active IP Right Cessation
- 1995-04-13 AU AU22199/95A patent/AU700773B2/en not_active Ceased
- 1995-04-13 JP JP52680695A patent/JP3782445B2/ja not_active Expired - Fee Related
-
1996
- 1996-10-07 FI FI964019A patent/FI114705B/fi active
- 1996-10-11 NO NO964345A patent/NO307177B1/no not_active IP Right Cessation
-
1998
- 1998-12-24 HK HK98115420A patent/HK1013999A1/xx not_active IP Right Cessation
-
2001
- 2001-08-31 GR GR20010401341T patent/GR3036482T3/el not_active IP Right Cessation
-
2004
- 2004-03-04 FI FI20040352A patent/FI115630B/fi active IP Right Grant
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Legal Events
Date | Code | Title | Description |
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FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
FF | Decision: intention to grant | ||
HJEG | Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law | ||
HIFF | Patent grant cancelled | ||
FF | Decision: intention to grant | ||
FG9A | Patent or certificate of addition granted | ||
B24H | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi) | ||
B24F | Patent annual fee: publication cancelled |
Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2257 DE 08/04/2014 POR TER SIDO INDEVIDA. |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AS 16A, 17A, 18A, 19A E 20A ANUIDADES. |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2606 DE 15-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |