SK281060B6 - Farmakologicky účinné enantioméry, spôsob ich prípravy, medziprodukty tohto postupu - Google Patents

Farmakologicky účinné enantioméry, spôsob ich prípravy, medziprodukty tohto postupu Download PDF

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Publication number
SK281060B6
SK281060B6 SK1664-95A SK166495A SK281060B6 SK 281060 B6 SK281060 B6 SK 281060B6 SK 166495 A SK166495 A SK 166495A SK 281060 B6 SK281060 B6 SK 281060B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
enantiomer
physiologically acceptable
acid
Prior art date
Application number
SK1664-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK166495A3 (en
Inventor
Leandro Baiocchi
Valerio Cioli
Original Assignee
Angelini Ricerche S. P. A. Societ� Consortile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricerche S. P. A. Societ� Consortile filed Critical Angelini Ricerche S. P. A. Societ� Consortile
Publication of SK166495A3 publication Critical patent/SK166495A3/sk
Publication of SK281060B6 publication Critical patent/SK281060B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1664-95A 1993-07-01 1994-06-21 Farmakologicky účinné enantioméry, spôsob ich prípravy, medziprodukty tohto postupu SK281060B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT93MI001418A IT1268414B1 (it) 1993-07-01 1993-07-01 Enantiomeri farmacologicamente attivi
PCT/EP1994/002061 WO1995001354A1 (fr) 1993-07-01 1994-06-21 Enantiomeres pharmacologiquement actifs

Publications (2)

Publication Number Publication Date
SK166495A3 SK166495A3 (en) 1996-09-04
SK281060B6 true SK281060B6 (sk) 2000-11-07

Family

ID=11366510

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1664-95A SK281060B6 (sk) 1993-07-01 1994-06-21 Farmakologicky účinné enantioméry, spôsob ich prípravy, medziprodukty tohto postupu

Country Status (30)

Country Link
US (3) US5741907A (fr)
EP (1) EP0707587B1 (fr)
JP (1) JP3096065B2 (fr)
KR (1) KR100306018B1 (fr)
CN (3) CN1046281C (fr)
AT (1) ATE158796T1 (fr)
AU (1) AU689478B2 (fr)
BG (1) BG61815B1 (fr)
BR (1) BR9406996A (fr)
CA (1) CA2166470C (fr)
CZ (1) CZ289526B6 (fr)
DE (1) DE69405999T2 (fr)
DK (1) DK0707587T3 (fr)
ES (1) ES2111309T3 (fr)
FI (1) FI111943B (fr)
GE (1) GEP19991791B (fr)
GR (1) GR3025806T3 (fr)
HK (2) HK1018781A1 (fr)
HU (1) HU221631B1 (fr)
IT (1) IT1268414B1 (fr)
LV (1) LV11546B (fr)
NO (1) NO305957B1 (fr)
NZ (1) NZ268014A (fr)
PL (1) PL181831B1 (fr)
RO (2) RO121031B1 (fr)
RU (1) RU2128180C1 (fr)
SK (1) SK281060B6 (fr)
UA (1) UA53607C2 (fr)
WO (1) WO1995001354A1 (fr)
ZA (1) ZA944570B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1268414B1 (it) * 1993-07-01 1997-02-27 Angelini Francesco Ist Ricerca Enantiomeri farmacologicamente attivi
JP2009018992A (ja) * 2007-07-10 2009-01-29 Sumitomo Chemical Co Ltd 光学活性ミルタザピンの製造方法
RU2706700C1 (ru) 2019-09-24 2019-11-20 Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3365453A (en) * 1963-10-28 1968-01-23 Sterling Drug Inc 1-phenyl-4-lower-alkyl-2-piperazinones
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
US5303837A (en) * 1991-03-05 1994-04-19 Portola Packaging, Inc. One-piece fitment and plug with tamper-evident band
US5739334A (en) * 1992-01-17 1998-04-14 Istituto Ricerca Francesco Angelini S.P.A. Alkyl derivatives of trazodone with CNS activity
GEP20001939B (en) * 1992-01-17 2000-02-05 Angelini Ricerca S P A Soc Consortile Alkyl Derivatives of Trazodone with CNS Activity
IT1268414B1 (it) * 1993-07-01 1997-02-27 Angelini Francesco Ist Ricerca Enantiomeri farmacologicamente attivi
US5399765A (en) * 1994-05-23 1995-03-21 Sepracor, Inc. Enantioselective preparation of optically pure albuterol

Also Published As

Publication number Publication date
NO305957B1 (no) 1999-08-23
GR3025806T3 (en) 1998-03-31
CA2166470C (fr) 2001-12-18
CZ289526B6 (cs) 2002-02-13
DE69405999T2 (de) 1998-04-16
FI111943B (fi) 2003-10-15
FI956334A (fi) 1996-02-19
CN1046281C (zh) 1999-11-10
ES2111309T3 (es) 1998-03-01
ITMI931418A0 (it) 1993-07-01
BG100331A (bg) 1996-09-30
DK0707587T3 (da) 1998-05-11
PL181831B1 (pl) 2001-09-28
KR100306018B1 (ko) 2001-11-30
PL312419A1 (en) 1996-04-15
RO121031B1 (ro) 2006-11-30
BR9406996A (pt) 1996-09-10
CN1136200C (zh) 2004-01-28
CN1215053A (zh) 1999-04-28
CN1136201C (zh) 2004-01-28
RO116899B1 (ro) 2001-07-30
AU7072994A (en) 1995-01-24
WO1995001354A1 (fr) 1995-01-12
ATE158796T1 (de) 1997-10-15
DE69405999D1 (de) 1997-11-06
NO955345L (no) 1996-02-29
LV11546A (lv) 1996-10-20
IT1268414B1 (it) 1997-02-27
HU9503876D0 (en) 1996-02-28
RU2128180C1 (ru) 1999-03-27
HK1018777A1 (en) 2000-01-07
HK1018781A1 (en) 2000-01-07
ITMI931418A1 (it) 1995-01-01
JPH08512036A (ja) 1996-12-17
CA2166470A1 (fr) 1995-01-12
HUT73230A (en) 1996-07-29
UA53607C2 (uk) 2003-02-17
CN1129939A (zh) 1996-08-28
HU221631B1 (hu) 2002-12-28
AU689478B2 (en) 1998-04-02
NO955345D0 (no) 1995-12-29
CZ348595A3 (en) 1996-04-17
ZA944570B (en) 1995-04-11
CN1215052A (zh) 1999-04-28
US5973150A (en) 1999-10-26
JP3096065B2 (ja) 2000-10-10
FI956334A0 (fi) 1995-12-29
US5817815A (en) 1998-10-06
LV11546B (en) 1997-02-20
BG61815B1 (bg) 1998-06-30
EP0707587A1 (fr) 1996-04-24
GEP19991791B (en) 1999-10-05
US5741907A (en) 1998-04-21
NZ268014A (en) 1997-08-22
SK166495A3 (en) 1996-09-04
EP0707587B1 (fr) 1997-10-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20090621