SK280326B6 - Deriváty acylovaných aminoalkylimidazolov a -triaz - Google Patents

Deriváty acylovaných aminoalkylimidazolov a -triaz Download PDF

Info

Publication number
SK280326B6
SK280326B6 SK635-95A SK63595A SK280326B6 SK 280326 B6 SK280326 B6 SK 280326B6 SK 63595 A SK63595 A SK 63595A SK 280326 B6 SK280326 B6 SK 280326B6
Authority
SK
Slovakia
Prior art keywords
pyridyl
chloro
formula
group
compounds
Prior art date
Application number
SK635-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK63595A3 (en
Inventor
Helmut Egger
Ingeborg Schuster
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK63595A3 publication Critical patent/SK63595A3/sk
Publication of SK280326B6 publication Critical patent/SK280326B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK635-95A 1994-05-18 1995-05-16 Deriváty acylovaných aminoalkylimidazolov a -triaz SK280326B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9409882A GB9409882D0 (en) 1994-05-18 1994-05-18 Organic compounds

Publications (2)

Publication Number Publication Date
SK63595A3 SK63595A3 (en) 1995-12-06
SK280326B6 true SK280326B6 (sk) 1999-11-08

Family

ID=10755289

Family Applications (1)

Application Number Title Priority Date Filing Date
SK635-95A SK280326B6 (sk) 1994-05-18 1995-05-16 Deriváty acylovaných aminoalkylimidazolov a -triaz

Country Status (30)

Country Link
US (1) US5622982A (fr)
EP (1) EP0683156B1 (fr)
JP (1) JP2912566B2 (fr)
KR (1) KR100371465B1 (fr)
CN (1) CN1060163C (fr)
AT (1) ATE164576T1 (fr)
AU (1) AU696880B2 (fr)
BR (1) BR9502062A (fr)
CA (1) CA2149459C (fr)
CO (1) CO4290423A1 (fr)
CZ (1) CZ285385B6 (fr)
DE (1) DE69501915T2 (fr)
DK (1) DK0683156T3 (fr)
ES (1) ES2114289T3 (fr)
FI (1) FI112364B (fr)
GB (1) GB9409882D0 (fr)
GR (1) GR3026505T3 (fr)
HK (1) HK1008743A1 (fr)
HU (1) HUT72063A (fr)
IL (1) IL113743A (fr)
MY (1) MY135559A (fr)
NO (1) NO304738B1 (fr)
NZ (1) NZ272129A (fr)
PE (1) PE14896A1 (fr)
PH (1) PH31510A (fr)
RU (1) RU2152933C2 (fr)
SI (1) SI0683156T1 (fr)
SK (1) SK280326B6 (fr)
TW (1) TW351718B (fr)
ZA (1) ZA954074B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0708771T3 (da) * 1993-07-15 1999-06-21 Pfizer Benzyloxyquinuclidiner som substans P antagonister
WO1997018817A1 (fr) * 1995-11-20 1997-05-29 Kiyoshi Kita Preparation externe contenant de la vitamine d ou de la vitamine k
WO1998053806A1 (fr) * 1997-05-26 1998-12-03 New Vision Co., Ltd. Compositions medicinales a administration topique renfermant les vitamines d et les vitamines k
US6034251A (en) * 1997-11-07 2000-03-07 Schering Corporation Phenyl-alkyl-imidazoles
TW575562B (en) * 1998-02-19 2004-02-11 Agrevo Uk Ltd Fungicides
CN1114593C (zh) * 1998-05-08 2003-07-16 陶氏益农有限责任公司 2位被取代的吡啶的制备
GB0029524D0 (en) * 2000-12-04 2001-01-17 Univ Sheffield Disease treatment
GB0128415D0 (en) * 2001-11-27 2002-01-16 Univ Sheffield Medicaments
US7429604B2 (en) * 2004-06-15 2008-09-30 Bristol Myers Squibb Company Six-membered heterocycles useful as serine protease inhibitors
WO2006036892A2 (fr) * 2004-09-24 2006-04-06 Sapphire Therapeutics, Inc. Utilisation d'inhibiteurs de 24-hydroxylase dans le traitement du cancer
WO2006032299A1 (fr) * 2004-09-24 2006-03-30 Susanna Miettinen Utilisation d'inhibiteurs de 24-hydroxylase dans le traitement d'un cancer
CN104530038A (zh) * 2014-12-10 2015-04-22 沈阳药科大学 酰胺咪唑类衍生物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2041771C3 (de) * 1970-08-22 1979-07-26 Bayer Ag, 5090 Leverkusen derivate
US4191767A (en) * 1977-01-07 1980-03-04 Westwood Pharmaceuticals, Inc. Method for treating fungal infection in mammals with imidazo [1,2-a]quinoxalines
CH655103A5 (de) * 1983-03-11 1986-03-27 Sandoz Ag Azolderivate, verfahren zu ihrer herstellung und ihre verwendung.
CH677925A5 (fr) * 1986-12-03 1991-07-15 Sandoz Ag

Also Published As

Publication number Publication date
KR950032147A (ko) 1995-12-20
PE14896A1 (es) 1996-05-09
EP0683156B1 (fr) 1998-04-01
FI952383A0 (fi) 1995-05-16
SI0683156T1 (en) 1998-06-30
CO4290423A1 (es) 1996-04-17
DE69501915D1 (de) 1998-05-07
EP0683156A1 (fr) 1995-11-22
HK1008743A1 (en) 1999-05-14
NO304738B1 (no) 1999-02-08
NO951944D0 (no) 1995-05-16
HUT72063A (en) 1996-03-28
CN1060163C (zh) 2001-01-03
FI112364B (fi) 2003-11-28
JPH0853422A (ja) 1996-02-27
TW351718B (en) 1999-02-01
DK0683156T3 (da) 1998-10-19
MY135559A (en) 2008-05-30
ZA954074B (en) 1996-11-18
DE69501915T2 (de) 1998-08-27
AU696880B2 (en) 1998-09-24
SK63595A3 (en) 1995-12-06
KR100371465B1 (ko) 2003-03-19
ATE164576T1 (de) 1998-04-15
BR9502062A (pt) 1996-04-30
RU2152933C2 (ru) 2000-07-20
PH31510A (en) 1998-11-03
HU9501451D0 (en) 1995-06-28
ES2114289T3 (es) 1998-05-16
CA2149459C (fr) 2006-09-19
IL113743A0 (en) 1995-08-31
NO951944L (no) 1995-11-20
FI952383A (fi) 1995-11-19
US5622982A (en) 1997-04-22
NZ272129A (en) 1996-05-28
CN1120039A (zh) 1996-04-10
AU2008995A (en) 1995-11-23
JP2912566B2 (ja) 1999-06-28
IL113743A (en) 1999-08-17
GR3026505T3 (en) 1998-07-31
CZ285385B6 (cs) 1999-07-14
RU95107652A (ru) 1997-03-20
GB9409882D0 (en) 1994-07-06
CZ126595A3 (en) 1995-11-15
CA2149459A1 (fr) 1995-11-19

Similar Documents

Publication Publication Date Title
KR100365312B1 (ko) N-[4-(헤테로아릴메틸)페닐]헤테로아릴아민
EP0966446B1 (fr) Inhibiteurs bicycliques de farnesyltransferase de proteine
EP1203767B1 (fr) Alkylamides substitués hétérocycliques à activité inhibitrice de l'acat
US7579352B2 (en) Retinoic acid mimetic anilides
EP1720872B1 (fr) Derives d'aryl- et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application comme inhibiteurs de l'enzyme faah
AU2005229459B9 (en) Therapeutic agents
US5925769A (en) Acetylenic 1,5-diarylpyrazoles as antiinflammatory agents
JP2008536818A (ja) １１−βヒドロキシステロイドデヒドロゲナーゼ阻害剤
US5684008A (en) Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
HU201300B (en) Process for production of derivatives of aryl and medical compositions containing them as active substance
CA2187932A1 (fr) Sulfamides substitues utilises comme agonistes selectifs vis-a-vis des recepteurs .beta.3-adrenergiques, pour le traitement du diabete et de l'obesite
US5922725A (en) Benzimidazole compounds and their use as modulators of the GABAA receptor complex
SK280326B6 (sk) Deriváty acylovaných aminoalkylimidazolov a -triaz
EP1539724B1 (fr) Composes d'amino benzothiazole a activite inhibitrice de nos
MX2011003991A (es) Antagonistas del receptor esfingosina-1-fosfato.
US4910212A (en) Heterocyclic compounds
PT100821B (pt) Compostos amino terciario substituidos com triazolilo e seus sais, e processo para a sua preparacao
SI9500392A (en) 5-lipoxygenase inhibitors.
RO113985B1 (ro) Derivati de 1 -(arilalchilaminoalchil) - imidazol, procedeu de preparare a acestora si compozitie farmaceutica continand acesti compusi
FR2556720A1 (fr) Derives de l'amidine et tonicardiaques les contenant
US5017604A (en) Novel fenamic acid methyl hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition
US5006543A (en) Diphenylethane derivatives
PL182101B1 (pl) Nowe pochodne acylowanych aminoalkanoimidazoli i srodek farmaceutyczny do selektywnego inhibitowania hydroksylaz 25-hydroksywitaminy D3 PL
US6166052A (en) Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers
WO2008152086A2 (fr) Dérivés de 4,5-dihydro-(1h)-pyrazole en tant que modulateurs des récepteurs cb1 cannabinoïdes

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100516