SK279618B6 - N-5-chránené 2,5-diamino-4,6-dichlórpyrimidíny a s - Google Patents

N-5-chránené 2,5-diamino-4,6-dichlórpyrimidíny a s Download PDF

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Publication number
SK279618B6
SK279618B6 SK3931-92A SK393192A SK279618B6 SK 279618 B6 SK279618 B6 SK 279618B6 SK 393192 A SK393192 A SK 393192A SK 279618 B6 SK279618 B6 SK 279618B6
Authority
SK
Slovakia
Prior art keywords
protected
formula
diamino
preparation
dichloropyrimidines
Prior art date
Application number
SK3931-92A
Other languages
English (en)
Slovak (sk)
Other versions
SK393192A3 (en
Inventor
Gerhard Stucky
Felix Previdoli
Original Assignee
Lonza A.G. (Dir.:Basel)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza A.G. (Dir.:Basel) filed Critical Lonza A.G. (Dir.:Basel)
Publication of SK393192A3 publication Critical patent/SK393192A3/sk
Publication of SK279618B6 publication Critical patent/SK279618B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
SK3931-92A 1992-01-22 1992-12-28 N-5-chránené 2,5-diamino-4,6-dichlórpyrimidíny a s SK279618B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH17992 1992-01-22

Publications (2)

Publication Number Publication Date
SK393192A3 SK393192A3 (en) 1995-09-13
SK279618B6 true SK279618B6 (sk) 1999-01-11

Family

ID=4181070

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3931-92A SK279618B6 (sk) 1992-01-22 1992-12-28 N-5-chránené 2,5-diamino-4,6-dichlórpyrimidíny a s

Country Status (19)

Country Link
US (1) US5294710A (fr)
EP (1) EP0552758B1 (fr)
JP (1) JP3252502B2 (fr)
KR (1) KR100262283B1 (fr)
CN (1) CN1077193A (fr)
AT (1) ATE154346T1 (fr)
AU (1) AU658965B2 (fr)
CA (1) CA2087880C (fr)
CZ (1) CZ287049B6 (fr)
DE (1) DE59306703D1 (fr)
DK (1) DK0552758T3 (fr)
ES (1) ES2104966T3 (fr)
FI (1) FI930238A (fr)
HU (1) HU219231B (fr)
IL (2) IL104478A (fr)
MX (1) MX9300267A (fr)
PL (2) PL171743B1 (fr)
SK (1) SK279618B6 (fr)
ZA (1) ZA93431B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402161D0 (en) 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
CA2145928C (fr) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide; methode de preparation
ES2204798T3 (es) * 1998-12-21 2004-05-01 Lonza Ag Procedimiento para la preparacion de 2,5-diamino-4,6-dihalogenopirimidina.
US6608199B2 (en) * 2000-07-07 2003-08-19 Syngenta Limited Synthesis of chlorinated pyrimidines
CN102702110A (zh) * 2012-05-24 2012-10-03 盛世泰科生物医药技术(苏州)有限公司 一种4-氨基-5,6-二氯嘧啶的制备方法
CN103936681B (zh) * 2014-04-04 2015-07-29 苏州开元民生科技股份有限公司 2-氨基-4,6-二氯-5-甲酰胺基嘧啶的制备方法
CN117050024B (zh) * 2023-10-13 2024-01-05 苏州开元民生科技股份有限公司 一种2-氨基-4,6-二氯-5-甲酰胺基嘧啶的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH649291A5 (de) * 1982-03-16 1985-05-15 Hoffmann La Roche Dicarbamate.
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process

Also Published As

Publication number Publication date
PL171137B1 (pl) 1997-03-28
IL104478A0 (en) 1993-05-13
DE59306703D1 (de) 1997-07-17
HUT63618A (en) 1993-09-28
MX9300267A (es) 1993-11-01
IL119700A0 (en) 1997-02-18
CA2087880C (fr) 2004-06-15
HU9300182D0 (en) 1993-04-28
US5294710A (en) 1994-03-15
ATE154346T1 (de) 1997-06-15
KR100262283B1 (ko) 2000-08-01
FI930238A (fi) 1993-07-23
AU658965B2 (en) 1995-05-04
DK0552758T3 (da) 1997-07-07
PL171743B1 (pl) 1997-06-30
AU3200193A (en) 1993-07-29
CN1077193A (zh) 1993-10-13
SK393192A3 (en) 1995-09-13
KR930016404A (ko) 1993-08-26
HU219231B (en) 2001-03-28
EP0552758B1 (fr) 1997-06-11
EP0552758A1 (fr) 1993-07-28
CA2087880A1 (fr) 1993-07-23
CZ393192A3 (en) 1993-08-11
FI930238A0 (fi) 1993-01-21
ZA93431B (en) 1993-08-25
JP3252502B2 (ja) 2002-02-04
PL297517A1 (en) 1993-08-23
ES2104966T3 (es) 1997-10-16
JPH05279344A (ja) 1993-10-26
IL104478A (en) 1997-06-10
CZ287049B6 (cs) 2000-08-16

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