SK278142B6 - 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxanes derivatives, method of their preparation and their use in therapy - Google Patents
2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxanes derivatives, method of their preparation and their use in therapy Download PDFInfo
- Publication number
- SK278142B6 SK278142B6 SK1837-91A SK183791A SK278142B6 SK 278142 B6 SK278142 B6 SK 278142B6 SK 183791 A SK183791 A SK 183791A SK 278142 B6 SK278142 B6 SK 278142B6
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- Slovakia
- Prior art keywords
- group
- principle
- naphthyl
- methoxy
- formula
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- 238000002360 preparation method Methods 0.000 title claims abstract description 6
- 238000002560 therapeutic procedure Methods 0.000 title abstract description 3
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- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims abstract description 6
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- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- WOXKDUGGOYFFRN-IIBYNOLFSA-N tadalafil Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C(C4=CC=CC=C4N3)C[C@H]3N2C(=O)CN(C3=O)C)=C1 WOXKDUGGOYFFRN-IIBYNOLFSA-N 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9007483A FR2663330B1 (fr) | 1990-06-15 | 1990-06-15 | 0derives de 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxanes, leur preparation et leur application en therapeutique. |
| FR9104578A FR2675143B3 (fr) | 1991-04-15 | 1991-04-15 | Derives de 2-(aminoalkyl)-5-naphtyl-1,3-dioxanes, leur preparation et leur application en therapeutique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK278142B6 true SK278142B6 (en) | 1996-02-07 |
Family
ID=26228078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1837-91A SK278142B6 (en) | 1990-06-15 | 1991-06-14 | 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxanes derivatives, method of their preparation and their use in therapy |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5192797A (cs) |
| EP (1) | EP0461958B1 (cs) |
| JP (1) | JPH0813808B2 (cs) |
| KR (1) | KR920000744A (cs) |
| AT (1) | ATE111460T1 (cs) |
| AU (1) | AU643290B2 (cs) |
| CA (1) | CA2044699A1 (cs) |
| CZ (1) | CZ280084B6 (cs) |
| DE (1) | DE69103968T2 (cs) |
| DK (1) | DK0461958T3 (cs) |
| ES (1) | ES2064057T3 (cs) |
| FI (1) | FI912888L (cs) |
| HU (1) | HU208432B (cs) |
| IE (1) | IE65067B1 (cs) |
| IL (1) | IL98454A (cs) |
| NO (1) | NO177995C (cs) |
| NZ (1) | NZ238557A (cs) |
| PL (1) | PL164840B1 (cs) |
| PT (1) | PT97991B (cs) |
| SK (1) | SK278142B6 (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2714055B1 (fr) * | 1993-12-22 | 1996-01-19 | Synthelabo | Dérivés de 5-(arylalkyl)-1,3-dioxane substitués en position 2, leur préparation et leur utilisation en thérapeutique. |
| FR2714056B1 (fr) * | 1993-12-22 | 1996-01-19 | Synthelabo | Dérivés de 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxane, leur préparation et leur application en thérapeutique. |
| FR2714058B1 (fr) * | 1993-12-22 | 1996-01-19 | Synthelabo | Dérivés de 1,3-dioxane trisubstitués, leur préparation et leur application en thérapeutique. |
| FR2720939B1 (fr) * | 1994-06-08 | 1996-07-12 | Synthelabo | Utilisation de dérivés de N-[[5-(naphtalén-1-yl)-1,3-dioxan-2-yl]alkyl] acétamide pour la préparation de médicaments utiles dans le traitement des désordres neurodégénératifs. |
| FR2742152B1 (fr) * | 1995-12-06 | 1998-01-16 | Synthelabo | Derives de 5-naphtalen-1-yl-1,3-dioxanes, leur preparation et leur application en therapeutique |
| FR2764287B1 (fr) * | 1997-06-05 | 1999-07-16 | Synthelabo | Derives de 5-naphtalen-1-yl-1,3-dioxanes, leur preparation et leur application en therapeutique |
| AR012908A1 (es) * | 1997-06-05 | 2000-11-22 | Vanmechelen Eugeen | Un compuesto derivado de 5-naftalen-1-il-1,3-dioxano bajo la forma de estereoisomero puro o de mezcla de estereoisomeros, medicamento que consisteen dicho compuesto, y composicion farmaceutica que contiene a dicho compuesto |
| FR2843964B1 (fr) | 2002-08-29 | 2004-10-01 | Sanofi Synthelabo | Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique |
| GB2397067B (en) * | 2002-12-23 | 2005-05-11 | Destiny Pharma Ltd | Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation |
| EP1604654A1 (en) * | 2004-05-18 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating dyskinesia |
| GB2415372A (en) | 2004-06-23 | 2005-12-28 | Destiny Pharma Ltd | Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent |
| US8470841B2 (en) | 2008-07-09 | 2013-06-25 | Sanofi | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| EP3244884A4 (en) | 2015-01-15 | 2018-07-25 | Allaysis, LLC | Intravenous baclofen formulations and treatment methods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1554878A (cs) * | 1967-12-12 | 1969-01-24 | ||
| US4116670A (en) * | 1977-04-04 | 1978-09-26 | Velsicol Chemical Company | Dioxane substituted amides |
| US4097491A (en) * | 1977-06-10 | 1978-06-27 | Velsicol Chemical Corporation | N-Dialkoxyalkyl-N-dioxanalkylene-α-haloalkanamides |
-
1991
- 1991-06-05 ES ES91401461T patent/ES2064057T3/es not_active Expired - Lifetime
- 1991-06-05 EP EP91401461A patent/EP0461958B1/fr not_active Expired - Lifetime
- 1991-06-05 DE DE69103968T patent/DE69103968T2/de not_active Expired - Lifetime
- 1991-06-05 AT AT91401461T patent/ATE111460T1/de not_active IP Right Cessation
- 1991-06-05 DK DK91401461.8T patent/DK0461958T3/da active
- 1991-06-11 IL IL9845491A patent/IL98454A/en not_active IP Right Cessation
- 1991-06-14 NZ NZ238557A patent/NZ238557A/en unknown
- 1991-06-14 CZ CS911837A patent/CZ280084B6/cs unknown
- 1991-06-14 SK SK1837-91A patent/SK278142B6/sk unknown
- 1991-06-14 NO NO912298A patent/NO177995C/no unknown
- 1991-06-14 US US07/714,182 patent/US5192797A/en not_active Expired - Fee Related
- 1991-06-14 JP JP3143090A patent/JPH0813808B2/ja not_active Expired - Lifetime
- 1991-06-14 IE IE204591A patent/IE65067B1/en not_active IP Right Cessation
- 1991-06-14 HU HU911992A patent/HU208432B/hu not_active IP Right Cessation
- 1991-06-14 FI FI912888A patent/FI912888L/fi not_active Application Discontinuation
- 1991-06-14 PT PT97991A patent/PT97991B/pt not_active IP Right Cessation
- 1991-06-14 CA CA002044699A patent/CA2044699A1/en not_active Abandoned
- 1991-06-14 KR KR1019910009826A patent/KR920000744A/ko not_active Ceased
- 1991-06-14 AU AU78433/91A patent/AU643290B2/en not_active Ceased
- 1991-06-14 PL PL91290676A patent/PL164840B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE111460T1 (de) | 1994-09-15 |
| AU643290B2 (en) | 1993-11-11 |
| PT97991A (pt) | 1992-03-31 |
| DK0461958T3 (da) | 1995-02-20 |
| NO177995C (no) | 1996-01-03 |
| DE69103968D1 (de) | 1994-10-20 |
| EP0461958A1 (fr) | 1991-12-18 |
| HU208432B (en) | 1993-10-28 |
| KR920000744A (ko) | 1992-01-29 |
| HU911992D0 (en) | 1991-12-30 |
| ES2064057T3 (es) | 1995-01-16 |
| IE912045A1 (en) | 1991-12-18 |
| HUT59124A (en) | 1992-04-28 |
| IL98454A0 (en) | 1992-07-15 |
| FI912888A7 (fi) | 1991-12-16 |
| EP0461958B1 (fr) | 1994-09-14 |
| PT97991B (pt) | 1998-11-30 |
| US5192797A (en) | 1993-03-09 |
| DE69103968T2 (de) | 1995-03-23 |
| NZ238557A (en) | 1992-04-28 |
| CZ280084B6 (cs) | 1995-10-18 |
| PL290676A1 (en) | 1991-12-16 |
| FI912888L (fi) | 1991-12-16 |
| IE65067B1 (en) | 1995-10-04 |
| PL164840B1 (pl) | 1994-10-31 |
| IL98454A (en) | 1996-07-23 |
| NO177995B (no) | 1995-09-25 |
| AU7843391A (en) | 1991-12-19 |
| CA2044699A1 (en) | 1991-12-16 |
| CS183791A3 (en) | 1992-01-15 |
| JPH0813808B2 (ja) | 1996-02-14 |
| NO912298L (no) | 1991-12-16 |
| FI912888A0 (fi) | 1991-06-14 |
| JPH04230277A (ja) | 1992-08-19 |
| NO912298D0 (no) | 1991-06-14 |
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