SK21495A3 - Vaccine against bordetella bronchiseptica on base of recombinant proteine of fimbris of these bacteries - Google Patents
Vaccine against bordetella bronchiseptica on base of recombinant proteine of fimbris of these bacteries Download PDFInfo
- Publication number
- SK21495A3 SK21495A3 SK214-95A SK21495A SK21495A3 SK 21495 A3 SK21495 A3 SK 21495A3 SK 21495 A SK21495 A SK 21495A SK 21495 A3 SK21495 A3 SK 21495A3
- Authority
- SK
- Slovakia
- Prior art keywords
- ala
- thr
- gly
- leu
- bronchiseptica
- Prior art date
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- 102000036639 antigens Human genes 0.000 description 1
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- 108010092854 aspartyllysine Proteins 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 229940125717 barbiturate Drugs 0.000 description 1
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 description 1
- AFYNADDZULBEJA-UHFFFAOYSA-N bicinchoninic acid Chemical compound C1=CC=CC2=NC(C=3C=C(C4=CC=CC=C4N=3)C(=O)O)=CC(C(O)=O)=C21 AFYNADDZULBEJA-UHFFFAOYSA-N 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000007465 bordet-gengou-medium Substances 0.000 description 1
- 210000004899 c-terminal region Anatomy 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000001886 ciliary effect Effects 0.000 description 1
- 210000000254 ciliated cell Anatomy 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
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- 238000010276 construction Methods 0.000 description 1
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- 230000009089 cytolysis Effects 0.000 description 1
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical group NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 description 1
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- 230000000694 effects Effects 0.000 description 1
- 238000001493 electron microscopy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- ZMMJGEGLRURXTF-UHFFFAOYSA-N ethidium bromide Chemical compound [Br-].C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CC)=C1C1=CC=CC=C1 ZMMJGEGLRURXTF-UHFFFAOYSA-N 0.000 description 1
- 229960005542 ethidium bromide Drugs 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 108010052305 exodeoxyribonuclease III Proteins 0.000 description 1
- -1 fimbriae Proteins 0.000 description 1
- 108020001507 fusion proteins Proteins 0.000 description 1
- 102000037865 fusion proteins Human genes 0.000 description 1
- 108010063718 gamma-glutamylaspartic acid Proteins 0.000 description 1
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- 238000001502 gel electrophoresis Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 108010013768 glutamyl-aspartyl-proline Proteins 0.000 description 1
- XBGGUPMXALFZOT-UHFFFAOYSA-N glycyl-L-tyrosine hemihydrate Natural products NCC(=O)NC(C(O)=O)CC1=CC=C(O)C=C1 XBGGUPMXALFZOT-UHFFFAOYSA-N 0.000 description 1
- 108010050848 glycylleucine Proteins 0.000 description 1
- 108010087823 glycyltyrosine Proteins 0.000 description 1
- 108010037850 glycylvaline Proteins 0.000 description 1
- STKYPAFSDFAEPH-LURJTMIESA-N glycylvaline Chemical compound CC(C)[C@@H](C(O)=O)NC(=O)CN STKYPAFSDFAEPH-LURJTMIESA-N 0.000 description 1
- 239000003228 hemolysin Substances 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 229940094991 herring sperm dna Drugs 0.000 description 1
- 229920000140 heteropolymer Polymers 0.000 description 1
- 230000006801 homologous recombination Effects 0.000 description 1
- 238000002744 homologous recombination Methods 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000000366 juvenile effect Effects 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 108010064235 lysylglycine Proteins 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010369 molecular cloning Methods 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229940051027 pasteurella multocida Drugs 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 108010031719 prolyl-serine Proteins 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 229940124551 recombinant vaccine Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
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- 230000000241 respiratory effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 108010071207 serylmethionine Proteins 0.000 description 1
- 239000013605 shuttle vector Substances 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 210000004894 snout Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
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- 230000002194 synthesizing effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- PBYZMCDFOULPGH-UHFFFAOYSA-N tungstate Chemical compound [O-][W]([O-])(=O)=O PBYZMCDFOULPGH-UHFFFAOYSA-N 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92202525 | 1992-08-18 | ||
| PCT/NL1993/000161 WO1994004683A1 (fr) | 1992-08-18 | 1993-07-28 | VACCIN CONTRE $i(BORDETELLA BRONCHISEPTICA) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK21495A3 true SK21495A3 (en) | 1995-07-11 |
Family
ID=8210860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK214-95A SK21495A3 (en) | 1992-08-18 | 1995-02-16 | Vaccine against bordetella bronchiseptica on base of recombinant proteine of fimbris of these bacteries |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5939064A (fr) |
| EP (1) | EP0656948B1 (fr) |
| JP (1) | JPH08500734A (fr) |
| AT (1) | ATE263244T1 (fr) |
| CA (1) | CA2142712C (fr) |
| CZ (1) | CZ285307B6 (fr) |
| DE (1) | DE69333467T2 (fr) |
| FI (1) | FI113242B (fr) |
| HU (1) | HU219819B (fr) |
| NO (1) | NO319988B1 (fr) |
| PL (1) | PL307505A1 (fr) |
| RU (1) | RU2129611C1 (fr) |
| SK (1) | SK21495A3 (fr) |
| WO (1) | WO1994004683A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2646776B1 (fr) | 1989-05-12 | 1994-06-03 | Pasteur Institut | Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella |
| FR2728170A1 (fr) * | 1994-12-15 | 1996-06-21 | Pasteur Institut | Vaccin de type acellulaire anti-bordetella |
| US6475754B1 (en) * | 1999-05-14 | 2002-11-05 | University Of Tennessee Research Corporation | Polynucleotides encoding Bordatella bronchiseptica fimbrial proteins (FimN), vectors, and expression systems therefor |
| WO2005071067A2 (fr) * | 2004-01-15 | 2005-08-04 | Intervet International B.V. | Agents stabilisateurs d'origine non animale et leurs procedes de production |
| US7521059B2 (en) * | 2004-06-14 | 2009-04-21 | Fenwick Bradley W | Kennel cough vaccine |
| AU2005317304B2 (en) * | 2004-12-17 | 2011-06-23 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws | Deacylation of LPS in Gram negative bacteria |
| CN112375127B (zh) * | 2020-11-25 | 2022-09-09 | 江苏省农业科学院 | 一种用作支气管败血波氏菌病疫苗的重组蛋白及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU575086B2 (en) * | 1983-11-07 | 1988-07-21 | Syntex (U.S.A.) Inc. | Bordetella bronchiseptica pili subunit protein and vaccine |
| DK594084A (da) * | 1984-12-12 | 1986-06-13 | Novo Industri As | Fremgangsmaade til stabilisering af extra-chromosomale elementer i bakterier under dyrkning |
| IT1223579B (it) * | 1987-12-22 | 1990-09-19 | Eniricerche Spa | Clonaggio e sequenziamento del gene codificante per una nuova subunita' pilinica di bordetella pertussis |
| IT1231961B (it) * | 1989-09-22 | 1992-01-16 | Eniricerche Spa | Clonaggio del gene codificante la subunita' pilinica fim3 di bordetella pertussis. |
-
1993
- 1993-07-28 EP EP93919704A patent/EP0656948B1/fr not_active Expired - Lifetime
- 1993-07-28 CA CA002142712A patent/CA2142712C/fr not_active Expired - Lifetime
- 1993-07-28 PL PL93307505A patent/PL307505A1/xx unknown
- 1993-07-28 DE DE69333467T patent/DE69333467T2/de not_active Expired - Lifetime
- 1993-07-28 HU HU9500491A patent/HU219819B/hu unknown
- 1993-07-28 US US08/381,881 patent/US5939064A/en not_active Expired - Lifetime
- 1993-07-28 CZ CZ95410A patent/CZ285307B6/cs not_active IP Right Cessation
- 1993-07-28 AT AT93919704T patent/ATE263244T1/de not_active IP Right Cessation
- 1993-07-28 RU RU95107705A patent/RU2129611C1/ru active
- 1993-07-28 WO PCT/NL1993/000161 patent/WO1994004683A1/fr active IP Right Grant
- 1993-07-28 JP JP6506121A patent/JPH08500734A/ja active Pending
-
1995
- 1995-02-16 NO NO19950582A patent/NO319988B1/no not_active IP Right Cessation
- 1995-02-16 SK SK214-95A patent/SK21495A3/sk not_active IP Right Cessation
- 1995-02-17 FI FI950740A patent/FI113242B/fi not_active IP Right Cessation
-
1999
- 1999-03-30 US US09/281,221 patent/US6284256B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HU9500491D0 (en) | 1995-04-28 |
| WO1994004683A1 (fr) | 1994-03-03 |
| FI950740A0 (fi) | 1995-02-17 |
| ATE263244T1 (de) | 2004-04-15 |
| NO950582L (no) | 1995-02-16 |
| HUT70984A (en) | 1995-11-28 |
| FI950740A (fi) | 1995-02-17 |
| HU219819B (hu) | 2001-08-28 |
| US6284256B1 (en) | 2001-09-04 |
| NO319988B1 (no) | 2005-10-10 |
| DE69333467D1 (de) | 2004-05-06 |
| FI113242B (fi) | 2004-03-31 |
| CA2142712C (fr) | 2004-01-06 |
| EP0656948B1 (fr) | 2004-03-31 |
| PL307505A1 (en) | 1995-05-29 |
| RU2129611C1 (ru) | 1999-04-27 |
| CZ41095A3 (en) | 1995-08-16 |
| NO950582D0 (no) | 1995-02-16 |
| CZ285307B6 (cs) | 1999-07-14 |
| CA2142712A1 (fr) | 1994-03-03 |
| JPH08500734A (ja) | 1996-01-30 |
| EP0656948A1 (fr) | 1995-06-14 |
| RU95107705A (ru) | 1997-03-27 |
| US5939064A (en) | 1999-08-17 |
| DE69333467T2 (de) | 2005-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC4A | Assignment and transfer of rights |
Owner name: PFIZER AG, ZUERICH, CH Free format text: FORMER OWNER: DIMMINACO AG/SA/LTD., BAAR, CH Effective date: 20101015 |
|
| TE4A | Change of owner's address |
Owner name: DIMMINACO AG/SA/LTD., BAAR, CH Effective date: 20101220 |
|
| MK4A | Patent expired |
Expiry date: 20130728 |