SK1942000A3 - PROCESS FOR THE FERMENTATIVE PRODUCTION OF L-AMINO ACIDS USINGì (54) CORYNEFORM BACTERIA - Google Patents
PROCESS FOR THE FERMENTATIVE PRODUCTION OF L-AMINO ACIDS USINGì (54) CORYNEFORM BACTERIA Download PDFInfo
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- SK1942000A3 SK1942000A3 SK194-2000A SK1942000A SK1942000A3 SK 1942000 A3 SK1942000 A3 SK 1942000A3 SK 1942000 A SK1942000 A SK 1942000A SK 1942000 A3 SK1942000 A3 SK 1942000A3
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- bacteria
- amino acids
- glutamate dehydrogenase
- amino acid
- plasmid vector
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- OOYGSFOGFJDDHP-KMCOLRRFSA-N kanamycin A sulfate Chemical compound OS(O)(=O)=O.O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N OOYGSFOGFJDDHP-KMCOLRRFSA-N 0.000 description 1
- 229960002064 kanamycin sulfate Drugs 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000012269 metabolic engineering Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000013586 microbial product Substances 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 229940066779 peptones Drugs 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229920001522 polyglycol ester Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000006268 reductive amination reaction Methods 0.000 description 1
- 238000010187 selection method Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
- C12Y104/01002—Glutamate dehydrogenase (1.4.1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/24—Proline; Hydroxyproline; Histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19907347A DE19907347A1 (de) | 1999-02-20 | 1999-02-20 | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| US09/324,940 US6355454B1 (en) | 1999-02-20 | 1999-06-03 | Process for the fermentative production of L-amino acids using coryneform bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK1942000A3 true SK1942000A3 (en) | 2000-09-12 |
Family
ID=26051968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK194-2000A SK1942000A3 (en) | 1999-02-20 | 2000-02-14 | PROCESS FOR THE FERMENTATIVE PRODUCTION OF L-AMINO ACIDS USINGì (54) CORYNEFORM BACTERIA |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1029919B1 (id) |
| JP (1) | JP2000236893A (id) |
| CN (1) | CN1222622C (id) |
| AT (1) | ATE263246T1 (id) |
| AU (1) | AU770187B2 (id) |
| BR (1) | BRPI0000897B1 (id) |
| CA (1) | CA2299105A1 (id) |
| ES (1) | ES2218009T3 (id) |
| HU (1) | HUP0000747A2 (id) |
| ID (1) | ID24801A (id) |
| RU (1) | RU2247778C2 (id) |
| SK (1) | SK1942000A3 (id) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3965821B2 (ja) * | 1999-03-09 | 2007-08-29 | 味の素株式会社 | Ｌ−リジンの製造法 |
| AU2001282132A1 (en) * | 2000-09-12 | 2002-03-26 | Degussa A.G. | Isolation and sequencing of the pknb gene of c. glutamicum |
| US6939692B2 (en) | 2000-09-12 | 2005-09-06 | Degussa Ag | Nucleotide sequences coding for the pknB gene |
| DE10045496A1 (de) | 2000-09-14 | 2002-03-28 | Degussa | Neue für das ptsi-Gen kodierende Nukleotidsequenzen |
| DE102004037572A1 (de) * | 2004-08-03 | 2006-02-23 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| JP2010017081A (ja) * | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| DE102006050489A1 (de) | 2006-10-26 | 2008-04-30 | Evonik Degussa Gmbh | Allele des prpD1-Gens aus coryneformen Bakterien |
| DE102006054202A1 (de) * | 2006-11-17 | 2008-05-21 | Evonik Degussa Gmbh | Allele des oxyR-Gens aus coryneformen Bakterien |
| CN101565723B (zh) * | 2009-05-25 | 2011-06-01 | 河南孟成生物药业股份有限公司 | 一种l-色氨酸的发酵生产工艺 |
| CN102653736A (zh) * | 2012-04-12 | 2012-09-05 | 大连大学 | 微生物发酵生产谷氨酸脱氢酶的方法 |
| CN103184247A (zh) * | 2013-04-08 | 2013-07-03 | 绍兴市安杰生物科技有限公司 | 一种l-赖氨酸联产l-乳酸的方法 |
| PL2811028T3 (pl) | 2013-06-03 | 2017-07-31 | Evonik Degussa Gmbh | Sposób wytwarzania L-waliny z zastosowaniem zrekombinowanych bakterii maczugowatych zawierających operon ilvBN indukowany propionianem |
| KR101518860B1 (ko) * | 2013-10-11 | 2015-05-12 | 씨제이제일제당 (주) | L-아미노산의 생산 방법 |
| RU2697005C2 (ru) * | 2013-10-11 | 2019-08-08 | СиДжей ЧЕИЛДЗЕДАНГ КОРП. | Способ получения l-аминокислот |
| CN105505894A (zh) * | 2014-09-24 | 2016-04-20 | 中国科学院天津工业生物技术研究所 | 天冬氨酸激酶/高丝氨酸脱氢酶突变体及其应用 |
| CN105506014B (zh) * | 2015-12-23 | 2019-02-12 | 湖南宝利士生物技术有限公司 | 高光学纯l-高丝氨酸及其衍生物的生物合成方法 |
| KR102112240B1 (ko) * | 2018-09-28 | 2020-05-18 | 씨제이제일제당 주식회사 | 알파-글루코시다제의 활성이 강화된 l-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산 생산 방법 |
| CN109337854B (zh) * | 2018-11-19 | 2020-11-03 | 南京工业大学 | 一株敲除胞外核酸酶ExeR的谷氨酸棒杆菌及其构建方法与应用 |
| CN111197014B (zh) * | 2020-04-01 | 2022-11-08 | 宜昌三峡普诺丁生物制药有限公司 | 谷氨酸棒状杆菌诱变菌株及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61268185A (ja) * | 1984-12-27 | 1986-11-27 | Asahi Chem Ind Co Ltd | グルタミン酸デヒドロゲナ−ゼ産生遺伝子を含むｄｎａ断片 |
| GB2223754B (en) * | 1988-09-12 | 1992-07-22 | Degussa | Dna encoding phosphoenolpyruvate carboxylase |
| DE3943117A1 (de) * | 1989-12-27 | 1991-07-04 | Forschungszentrum Juelich Gmbh | Verfahren zur fermentativen herstellung von aminosaeure, insbesondere l-lysin, dafuer geeignete mikroorganismen und rekombinante dna |
| FI980551A (fi) * | 1998-03-11 | 1999-09-12 | Valtion Teknillinen | Transformoidut mikro-organismit, joilla on parannettuja ominaisuuksia |
-
2000
- 2000-02-08 AT AT00102601T patent/ATE263246T1/de not_active IP Right Cessation
- 2000-02-08 ES ES00102601T patent/ES2218009T3/es not_active Expired - Lifetime
- 2000-02-08 EP EP00102601A patent/EP1029919B1/de not_active Expired - Lifetime
- 2000-02-14 SK SK194-2000A patent/SK1942000A3/sk unknown
- 2000-02-17 JP JP2000040048A patent/JP2000236893A/ja active Pending
- 2000-02-18 ID IDP20000125A patent/ID24801A/id unknown
- 2000-02-18 HU HU0000747A patent/HUP0000747A2/hu unknown
- 2000-02-18 AU AU17600/00A patent/AU770187B2/en not_active Ceased
- 2000-02-18 CA CA002299105A patent/CA2299105A1/en not_active Abandoned
- 2000-02-18 RU RU2000103965/13A patent/RU2247778C2/ru not_active IP Right Cessation
- 2000-02-18 CN CNB00102728XA patent/CN1222622C/zh not_active Expired - Lifetime
- 2000-02-21 BR BRPI0000897A patent/BRPI0000897B1/pt active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2299105A1 (en) | 2000-08-20 |
| ES2218009T3 (es) | 2004-11-16 |
| AU770187B2 (en) | 2004-02-12 |
| EP1029919A2 (de) | 2000-08-23 |
| JP2000236893A (ja) | 2000-09-05 |
| EP1029919A3 (de) | 2001-11-07 |
| ID24801A (id) | 2000-08-24 |
| EP1029919B1 (de) | 2004-03-31 |
| HU0000747D0 (en) | 2000-04-28 |
| BRPI0000897B1 (pt) | 2016-11-22 |
| CN1266905A (zh) | 2000-09-20 |
| RU2247778C2 (ru) | 2005-03-10 |
| CN1222622C (zh) | 2005-10-12 |
| HUP0000747A2 (en) | 2002-09-28 |
| BR0000897A (pt) | 2001-05-02 |
| AU1760000A (en) | 2000-08-24 |
| ATE263246T1 (de) | 2004-04-15 |
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