SK18672001A3 - Polymorfné formy kryštalického (2-benzhydryl-1-azabicyklo [2.2.2]okt-3-yl)-(5-izopropyl-2-metoxybenzyl)-amóniumchloridu ako antagonisty receptora NK-1 - Google Patents
Polymorfné formy kryštalického (2-benzhydryl-1-azabicyklo [2.2.2]okt-3-yl)-(5-izopropyl-2-metoxybenzyl)-amóniumchloridu ako antagonisty receptora NK-1 Download PDFInfo
- Publication number
- SK18672001A3 SK18672001A3 SK1867-2001A SK18672001A SK18672001A3 SK 18672001 A3 SK18672001 A3 SK 18672001A3 SK 18672001 A SK18672001 A SK 18672001A SK 18672001 A3 SK18672001 A3 SK 18672001A3
- Authority
- SK
- Slovakia
- Prior art keywords
- dihydrochloride
- dihydrate
- anhydrous
- water
- polymorph
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14023399P | 1999-06-22 | 1999-06-22 | |
| PCT/IB2000/000756 WO2000078759A1 (en) | 1999-06-22 | 2000-06-06 | Polymorphs of crystalline (2-benzhydryl-1-azabicyclo[2,2,2]oct-3-yl)-(5-isopropyl-2-methoxybenzyl)-ammoniumchloride as nk-1 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK18672001A3 true SK18672001A3 (sk) | 2002-08-06 |
Family
ID=22490317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1867-2001A SK18672001A3 (sk) | 1999-06-22 | 2000-06-06 | Polymorfné formy kryštalického (2-benzhydryl-1-azabicyklo [2.2.2]okt-3-yl)-(5-izopropyl-2-metoxybenzyl)-amóniumchloridu ako antagonisty receptora NK-1 |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6262067B1 (pt) |
| EP (1) | EP1187834A1 (pt) |
| JP (1) | JP2003502425A (pt) |
| KR (1) | KR20020030280A (pt) |
| CN (1) | CN1390216A (pt) |
| AP (1) | AP2001002367A0 (pt) |
| AR (1) | AR024411A1 (pt) |
| AU (1) | AU767336B2 (pt) |
| BG (1) | BG106205A (pt) |
| BR (1) | BR0011835A (pt) |
| CA (1) | CA2375265A1 (pt) |
| CO (1) | CO5190663A1 (pt) |
| CZ (1) | CZ20014458A3 (pt) |
| DZ (1) | DZ3055A1 (pt) |
| EA (1) | EA004264B1 (pt) |
| EC (1) | ECSP003538A (pt) |
| EE (1) | EE200100698A (pt) |
| HR (1) | HRP20010920A2 (pt) |
| HU (1) | HUP0201694A3 (pt) |
| IL (1) | IL146410A0 (pt) |
| IS (1) | IS6161A (pt) |
| MA (1) | MA26744A1 (pt) |
| MX (1) | MXPA02000033A (pt) |
| NO (1) | NO20016187L (pt) |
| NZ (1) | NZ515348A (pt) |
| OA (1) | OA11952A (pt) |
| PA (1) | PA8496701A1 (pt) |
| PE (1) | PE20010322A1 (pt) |
| PL (1) | PL352899A1 (pt) |
| SK (1) | SK18672001A3 (pt) |
| TN (1) | TNSN00137A1 (pt) |
| TR (1) | TR200103688T2 (pt) |
| UY (1) | UY26211A1 (pt) |
| WO (1) | WO2000078759A1 (pt) |
| ZA (1) | ZA200110387B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6387925B1 (en) * | 1999-06-01 | 2002-05-14 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo (2.2.2) oct-3-yl amine citrate and their pharmaceutical compositions |
| US6756379B2 (en) * | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US7683071B2 (en) * | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US6939873B2 (en) | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
| JP2006503859A (ja) * | 2002-10-04 | 2006-02-02 | メルク シャープ エンド ドーム リミテッド | 受容体拮抗薬としてのアザ二環式スピロエーテル誘導体 |
| AR042444A1 (es) | 2002-12-11 | 2005-06-22 | Taro Pharmaceuticals Ireland L | Metodo para el tratamiento de desordenes del movimiento mediante la utilizacion de acido barbiturico |
| EP1781624A4 (en) * | 2004-07-02 | 2010-06-23 | Taro Pharma Ind | PROCESS FOR THE PREPARATION OF 1-METHOXYMETHYL-5,5-DIPHENYLBARBITURIC ACID |
| EP2081576A4 (en) * | 2006-11-14 | 2010-06-30 | Taro Pharmaceuticals North Ame | METHOD FOR IMPROVING BIOAVAILABILITY FOR NON-EDMING BARBITURATES |
| UA102128C2 (en) * | 2008-12-05 | 2013-06-10 | Х. Луннбек А/С | Nalmefene hydrochloride dihydrate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX18467A (es) * | 1988-11-23 | 1993-07-01 | Pfizer | Agentes terapeuticos de quinuclidinas |
| RU2103269C1 (ru) * | 1991-05-31 | 1998-01-27 | Пфайзер Инк. | Производные хинуклидина или их фармацевтически приемлемые соли и фармацевтическая композиция |
| KR950704311A (ko) * | 1992-11-12 | 1995-11-17 | 알렌 제이. 스피겔 | 물질 p 길항체로서의 퀴누클리딘 유도체(quinuclidine derivative as substance p antagonist) |
| US5393762A (en) * | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
-
2000
- 2000-05-04 US US09/564,528 patent/US6262067B1/en not_active Expired - Fee Related
- 2000-06-06 HU HU0201694A patent/HUP0201694A3/hu unknown
- 2000-06-06 OA OA1200100314A patent/OA11952A/en unknown
- 2000-06-06 CN CN00809305A patent/CN1390216A/zh active Pending
- 2000-06-06 PA PA20008496701A patent/PA8496701A1/es unknown
- 2000-06-06 PL PL00352899A patent/PL352899A1/xx not_active Application Discontinuation
- 2000-06-06 WO PCT/IB2000/000756 patent/WO2000078759A1/en not_active Application Discontinuation
- 2000-06-06 KR KR1020017016407A patent/KR20020030280A/ko not_active Application Discontinuation
- 2000-06-06 SK SK1867-2001A patent/SK18672001A3/sk unknown
- 2000-06-06 CA CA002375265A patent/CA2375265A1/en not_active Abandoned
- 2000-06-06 TR TR2001/03688T patent/TR200103688T2/xx unknown
- 2000-06-06 EP EP00929745A patent/EP1187834A1/en not_active Withdrawn
- 2000-06-06 AP APAP/P/2001/002367A patent/AP2001002367A0/en unknown
- 2000-06-06 JP JP2001504925A patent/JP2003502425A/ja active Pending
- 2000-06-06 IL IL14641000A patent/IL146410A0/xx unknown
- 2000-06-06 EA EA200101179A patent/EA004264B1/ru not_active IP Right Cessation
- 2000-06-06 AU AU47745/00A patent/AU767336B2/en not_active Ceased
- 2000-06-06 NZ NZ515348A patent/NZ515348A/en unknown
- 2000-06-06 CZ CZ20014458A patent/CZ20014458A3/cs unknown
- 2000-06-06 MX MXPA02000033A patent/MXPA02000033A/es unknown
- 2000-06-06 EE EEP200100698A patent/EE200100698A/xx unknown
- 2000-06-06 BR BR0011835-4A patent/BR0011835A/pt not_active IP Right Cessation
- 2000-06-13 CO CO00043885A patent/CO5190663A1/es not_active Application Discontinuation
- 2000-06-20 PE PE2000000613A patent/PE20010322A1/es not_active Application Discontinuation
- 2000-06-20 AR ARP000103053A patent/AR024411A1/es not_active Application Discontinuation
- 2000-06-20 UY UY26211A patent/UY26211A1/es not_active Application Discontinuation
- 2000-06-21 DZ DZ000113A patent/DZ3055A1/xx active
- 2000-06-21 MA MA26007A patent/MA26744A1/fr unknown
- 2000-06-21 TN TNTNSN00137A patent/TNSN00137A1/fr unknown
- 2000-06-22 EC EC2000003538A patent/ECSP003538A/es unknown
-
2001
- 2001-11-13 IS IS6161A patent/IS6161A/is unknown
- 2001-12-10 BG BG106205A patent/BG106205A/bg unknown
- 2001-12-11 HR HR20010920A patent/HRP20010920A2/hr not_active Application Discontinuation
- 2001-12-18 NO NO20016187A patent/NO20016187L/no not_active Application Discontinuation
- 2001-12-19 ZA ZA200110387A patent/ZA200110387B/en unknown
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