SK14598A3 - 4-mercaptopyrrolidine derivatives as farnesyl transferase inhibitors - Google Patents
4-mercaptopyrrolidine derivatives as farnesyl transferase inhibitors Download PDFInfo
- Publication number
- SK14598A3 SK14598A3 SK145-98A SK14598A SK14598A3 SK 14598 A3 SK14598 A3 SK 14598A3 SK 14598 A SK14598 A SK 14598A SK 14598 A3 SK14598 A3 SK 14598A3
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- alkyl
- phenyl
- compound
- carbon atoms
- Prior art date
Links
- 0 CC(C)(C)OC(S[C@](C1)C[C@@](C*)*1C(OCC=C)=O)=O Chemical compound CC(C)(C)OC(S[C@](C1)C[C@@](C*)*1C(OCC=C)=O)=O 0.000 description 5
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515975.2A GB9515975D0 (en) | 1995-08-04 | 1995-08-04 | Chemical compounds |
| PCT/GB1996/001810 WO1997006138A1 (fr) | 1995-08-04 | 1996-07-30 | Derives de 4-mercaptopyrrolidine en tant qu'inhibiteurs de farnesyle transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK14598A3 true SK14598A3 (en) | 1998-09-09 |
Family
ID=10778742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK145-98A SK14598A3 (en) | 1995-08-04 | 1996-07-30 | 4-mercaptopyrrolidine derivatives as farnesyl transferase inhibitors |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6232338B1 (fr) |
| EP (1) | EP0842151A1 (fr) |
| JP (1) | JPH11510178A (fr) |
| KR (1) | KR100502770B1 (fr) |
| CN (2) | CN1101380C (fr) |
| AU (1) | AU720353B2 (fr) |
| BR (1) | BR9609701A (fr) |
| CA (1) | CA2226671C (fr) |
| CZ (1) | CZ293694B6 (fr) |
| GB (1) | GB9515975D0 (fr) |
| HU (1) | HUP9802857A3 (fr) |
| IL (1) | IL123155A0 (fr) |
| MX (1) | MX9800946A (fr) |
| MY (1) | MY141457A (fr) |
| NO (2) | NO316624B1 (fr) |
| NZ (1) | NZ313696A (fr) |
| PL (1) | PL190873B1 (fr) |
| RU (1) | RU2191773C2 (fr) |
| SK (1) | SK14598A3 (fr) |
| TR (2) | TR199800147T1 (fr) |
| TW (1) | TW345575B (fr) |
| WO (1) | WO1997006138A1 (fr) |
| ZA (1) | ZA966610B (fr) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6310095B1 (en) | 1995-11-06 | 2001-10-30 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6204293B1 (en) | 1995-11-06 | 2001-03-20 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6693123B2 (en) | 1995-11-06 | 2004-02-17 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6221865B1 (en) | 1995-11-06 | 2001-04-24 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| WO1998007692A1 (fr) * | 1996-08-17 | 1998-02-26 | Zeneca Limited | 3-mercaptopyrrolidines comme inhibiteurs de la farnesyle-proteine transferase |
| CA2288330C (fr) | 1997-05-07 | 2014-02-11 | University Of Pittsburgh | Derives d'acide benzoyl-amino utiles en tant qu'inhibiteurs de proteinesisoprenyle transferases |
| JP2001520222A (ja) | 1997-10-22 | 2001-10-30 | ゼネカ・リミテッド | イミダゾール誘導体およびファルネシルタンパク質トランスフェラーゼインヒビターとしてのそれらの使用 |
| DK1025088T3 (da) | 1997-10-22 | 2001-11-12 | Astrazeneca Ab | Imidazolderivater og deres anvendelse som farnesylproteintransferaseinhibitorer |
| WO1999041235A1 (fr) * | 1998-02-10 | 1999-08-19 | Astrazeneca Uk Limited | Inhibiteurs de la farnesyle transferase |
| GB9930317D0 (en) * | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| GB9930318D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
| ITRM20020016A1 (it) * | 2002-01-15 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| EP1539234A4 (fr) * | 2002-09-05 | 2006-02-15 | Medimmune Inc | Methodes de prevention ou de traitement de malignites cellulaires par administration d'antagonistes de cd2 |
| US8034831B2 (en) * | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| US7563810B2 (en) * | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| EP2316487B1 (fr) | 2003-04-11 | 2014-06-11 | MedImmune, LLC | Anticorps IL-9 recombinants et leurs utilisations |
| JP4934426B2 (ja) | 2003-08-18 | 2012-05-16 | メディミューン，エルエルシー | 抗体のヒト化 |
| US20060228350A1 (en) * | 2003-08-18 | 2006-10-12 | Medimmune, Inc. | Framework-shuffling of antibodies |
| EP1667991B1 (fr) | 2003-09-16 | 2008-05-14 | Astrazeneca AB | Derives de quinazoline utilises comme inhibiteurs de la tyrosine kinase |
| WO2005089515A2 (fr) * | 2004-03-18 | 2005-09-29 | The Brigham And Women's Hospital, Inc. | Procedes de traitement des synucleinopathies |
| WO2005089502A2 (fr) * | 2004-03-18 | 2005-09-29 | The Brigham And Women's Hospital, Inc. | Traitement des synucleinopathies |
| WO2005089504A2 (fr) * | 2004-03-18 | 2005-09-29 | The Brigham And Women's Hospital, Inc. | Procedes pour le traitement de synucleinopathies |
| US20070293539A1 (en) * | 2004-03-18 | 2007-12-20 | Lansbury Peter T | Methods for the treatment of synucleinopathies |
| WO2005089496A2 (fr) * | 2004-03-18 | 2005-09-29 | The Brigham And Women's Hospital, Inc. | Procédés pour le traitement de synucléinopathies |
| EP2422811A2 (fr) | 2004-10-27 | 2012-02-29 | MedImmune, LLC | Modulation d'une spécificité d'anticorps par adaptation sur mesure de son affinité a une antigène apparente |
| JP5153613B2 (ja) | 2005-03-18 | 2013-02-27 | メディミューン，エルエルシー | 抗体のフレームワーク・シャッフル |
| KR20080025174A (ko) | 2005-06-23 | 2008-03-19 | 메디뮨 인코포레이티드 | 응집 및 단편화 프로파일이 최적화된 항체 제제 |
| WO2007092285A2 (fr) * | 2006-02-02 | 2007-08-16 | Link Medicine Corporation | Traitement de synucléinopathies |
| JP5209625B2 (ja) | 2006-08-28 | 2013-06-12 | 協和発酵キリン株式会社 | アンタゴニストのヒトｌｉｇｈｔ特異的ヒトモノクローナル抗体 |
| AU2008232902B2 (en) | 2007-03-30 | 2013-10-03 | Medlmmune, Llc | Antibody formulation |
| CN101376656A (zh) * | 2007-08-30 | 2009-03-04 | 山东轩竹医药科技有限公司 | 培南衍生物 |
| KR101686247B1 (ko) | 2007-10-31 | 2016-12-14 | 메디뮨 엘엘씨 | 단백질 스캐폴드 |
| US8232402B2 (en) * | 2008-03-12 | 2012-07-31 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
| EP2370436A1 (fr) * | 2008-11-13 | 2011-10-05 | Link Medicine Corporation | Dérivés d'azaquinolinone et leurs applications |
| US20110060005A1 (en) * | 2008-11-13 | 2011-03-10 | Link Medicine Corporation | Treatment of mitochondrial disorders using a farnesyl transferase inhibitor |
| US20100331363A1 (en) * | 2008-11-13 | 2010-12-30 | Link Medicine Corporation | Treatment of mitochondrial disorders using a farnesyl transferase inhibitor |
| JP2012520884A (ja) | 2009-03-18 | 2012-09-10 | ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニバーシティー | フラビウイルス科ウイルス感染症を治療する方法および組成物 |
| DK2668210T3 (da) | 2011-01-26 | 2020-08-24 | Celldex Therapeutics Inc | Anti-kit antistoffer og anvendelser deraf |
| US9250552B2 (en) * | 2011-03-30 | 2016-02-02 | Canon Kabushiki Kaisha | Polymerizable monomer, polymeric compound, charge control agent containing the polymeric compound, and developer bearing member and toner which contain the charge control agent |
| CN116574185A (zh) | 2012-07-25 | 2023-08-11 | 塞尔德克斯医疗公司 | 抗kit抗体及其用途 |
| CA2887129A1 (fr) | 2012-10-09 | 2014-04-17 | Igenica, Inc. | Anticorps anti-c16orf54 et leurs methodes d'utilisation |
| SG11201509982UA (fr) | 2013-06-06 | 2016-04-28 | Igenica Biotherapeutics Inc | |
| DK3041507T3 (da) | 2013-08-26 | 2021-07-26 | Biontech Res And Development Inc | Nukleinsyrer, der koder for humane antistoffer mod sialyl-lewis a |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| KR102614642B1 (ko) | 2014-06-04 | 2023-12-19 | 바이오엔테크 리서치 앤드 디벨롭먼트 인코포레이티드 | 강글리오사이드 ｇｄ２에 대한 사람 단클론 항체 |
| PT3333191T (pt) | 2014-12-11 | 2020-12-15 | Pf Medicament | Anticorpos anti-c10orf54 e suas utilizações |
| BR112017015880A2 (pt) | 2015-03-03 | 2018-07-31 | Kymab Ltd | anticorpos, usos e métodos |
| EP3319938B1 (fr) * | 2015-07-10 | 2022-04-06 | University of Maryland, Baltimore | Inhibiteurs à petites molécules de l'oncoprotéine mcl-1 et leurs utilisations |
| EP3909983A1 (fr) | 2015-12-02 | 2021-11-17 | STCube & Co. Inc. | Anticorps et molécules se liant de manière immunospécifique à btn1a1 et leurs utilisations thérapeutiques |
| KR20180100122A (ko) | 2015-12-02 | 2018-09-07 | 주식회사 에스티사이언스 | 당화된 btla(b- 및 t-림프구 약화인자)에 특이적인 항체 |
| EP3534947A1 (fr) | 2016-11-03 | 2019-09-11 | Kymab Limited | Anticorps, combinaisons comprenant des anticorps, biomarqueurs, utilisations et procédés |
| CN111051346A (zh) | 2017-05-31 | 2020-04-21 | 斯特库伯株式会社 | 使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法 |
| KR20200015602A (ko) | 2017-05-31 | 2020-02-12 | 주식회사 에스티큐브앤컴퍼니 | Btn1a1에 면역특이적으로 결합하는 항체 및 분자 및 이의 치료적 용도 |
| EP3635007A1 (fr) | 2017-06-06 | 2020-04-15 | STCube & Co., Inc. | Procédés de traitement du cancer à l'aide d'anticorps et de molécules se liant à btn1a1 ou des ligands de btn1a1 |
| US11707522B2 (en) | 2017-10-13 | 2023-07-25 | Boehringer Ingelheim International Gmbh | Human antibodies to Tn antigen |
| EP3824287A1 (fr) | 2018-07-20 | 2021-05-26 | Pierre Fabre Médicament | Récepteur pour vista |
| GB201908453D0 (en) * | 2019-06-12 | 2019-07-24 | Enterprise Therapeutics Ltd | Compounds for treating respiratory disease |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1283906C (fr) | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | COMPOSE DE .beta.-LACTAM ET PROCEDE DE PRODUCTION |
| JPS60233076A (ja) | 1984-05-03 | 1985-11-19 | Sumitomo Chem Co Ltd | 新規なβ−ラクタム化合物およびその製造法 |
| DE3579888D1 (de) | 1984-11-08 | 1990-10-31 | Sumitomo Pharma | Carbapenemverbindungen und deren herstellung. |
| KR880006244A (ko) | 1986-11-24 | 1988-07-22 | 후지사와 도모 기찌 로 | 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법 |
| GB8921635D0 (en) | 1989-09-25 | 1989-11-08 | Fujisawa Pharmaceutical Co | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives |
| CA2036163C (fr) | 1990-02-14 | 2001-06-19 | Makoto Sunagawa | Nouveaux composes de beta-lactame et leur production |
| IE910606A1 (en) | 1990-02-23 | 1991-08-28 | Sankyo Co | Carbapenem derivatives having antibiotic activity, their¹preparation and their use |
| GB9107363D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| US6083917A (en) * | 1990-04-18 | 2000-07-04 | Board Of Regents, The University Of Texas System | Methods and compositions for the identification, characterization and inhibition of farnesyltransferase |
| US5185248A (en) | 1990-05-08 | 1993-02-09 | E. R. Squibb & Sons, Inc. | Farnesyl-protein transferase assay for identifying compounds that block neoplastic transformation |
| JPH0578360A (ja) | 1991-01-31 | 1993-03-30 | Banyu Pharmaceut Co Ltd | ２−［２−（スルフアモイルアルキル）ピロリジニルチオカルバペネム誘導体 |
| GB9107341D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| GB9107342D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| RU2093514C1 (ru) | 1991-06-04 | 1997-10-20 | Санкио Компани Лимитед | Производные 1-метилкарбапенема и способ их получения |
| JPH04368386A (ja) | 1991-06-18 | 1992-12-21 | Sankyo Co Ltd | １−メチルカルバペネム−３−カルボン酸の製造法 |
| US5360798A (en) | 1991-07-04 | 1994-11-01 | Shionogi Seiyaku Kabushiki Kaisha | Aminooxypyrrolidinylthiocarbapenem compounds |
| DK0537007T3 (da) | 1991-10-11 | 1995-09-25 | Squibb & Sons Inc | Anvendelse af farnesyl-protein-transferase-inhibitorer til fremstilling af et lægemiddel til blokering af neoplastisk transformation af celler fremkaldt af ras-oncogener |
| JPH05239058A (ja) | 1991-12-17 | 1993-09-17 | Fujisawa Pharmaceut Co Ltd | ３−ピロリジニルチオ−１−アザビシクロ［３．２．０ヘプト−２−エン−２−カルボン酸化合物 |
| GB9202298D0 (en) | 1992-02-04 | 1992-03-18 | Ici Plc | Antibiotic compounds |
| CZ290002B6 (cs) | 1992-03-11 | 2002-05-15 | Sankyo Company Limited | Antimikrobiální karbapenemové deriváty, způsob výroby a farmaceutický prostředek |
| CA2091309A1 (fr) | 1992-03-26 | 1993-09-27 | Frederic H. Jung | Composes antibiotiques |
| GB9304156D0 (en) | 1992-03-26 | 1993-04-21 | Zeneca Ltd | Antibiotic compounds |
| WO1993021186A1 (fr) | 1992-04-13 | 1993-10-28 | Fujisawa Pharmaceutical Co., Ltd. | 3-pyrrolidinylthio-carbapenemes substitues, utilises comme agents antimicrobiens |
| EP0581501B1 (fr) | 1992-07-21 | 1998-09-09 | Zeneca Limited | Dérivés de carbapénème antibiotiques |
| CA2099818A1 (fr) | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Composes antibiotiques |
| EP0581502B1 (fr) | 1992-07-21 | 1998-10-21 | Zeneca Limited | Dérivés de carbapénème antibiotiques |
| EP0590885B1 (fr) | 1992-09-28 | 2000-03-15 | Zeneca Limited | Dérivés de carbapénème antibiotiques |
| CA2106330A1 (fr) | 1992-10-07 | 1994-04-08 | Patrice J. Siret | Composes antibiotiques |
| CA2118985A1 (fr) | 1993-04-02 | 1994-10-03 | Dinesh V. Patel | Inhibiteurs heterocycliques de la farnesyl proteine transferase |
| CA2165176A1 (fr) | 1993-06-18 | 1995-01-05 | Samuel L. Graham | Inhibiteurs de la farnesyl-proteine transferase |
| US5468733A (en) * | 1993-09-30 | 1995-11-21 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US5576293A (en) * | 1993-09-30 | 1996-11-19 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| CN1151156A (zh) | 1994-03-15 | 1997-06-04 | 卫材株式会社 | 异戊二烯基转移酶抑制剂 |
| CA2155448A1 (fr) * | 1994-08-11 | 1996-02-12 | Katerina Leftheris | Inhibiteurs de la farnesyl-proteine-transferase |
| US5571835A (en) * | 1994-09-29 | 1996-11-05 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| ES2196163T3 (es) | 1995-07-31 | 2003-12-16 | Shionogi & Co | Derivados de pirrolidina con una actividad de inhibicion de la fosfolipasa a2. |
| JP3115285B2 (ja) | 1999-04-27 | 2000-12-04 | 徳光 中ノ瀬 | 合成樹脂体を利用した水上施設 |
-
1995
- 1995-08-04 GB GBGB9515975.2A patent/GB9515975D0/en active Pending
-
1996
- 1996-07-23 TW TW085108987A patent/TW345575B/zh active
- 1996-07-30 PL PL324819A patent/PL190873B1/pl not_active IP Right Cessation
- 1996-07-30 TR TR1998/00147T patent/TR199800147T1/xx unknown
- 1996-07-30 IL IL12315596A patent/IL123155A0/xx not_active IP Right Cessation
- 1996-07-30 RU RU98103393/04A patent/RU2191773C2/ru not_active IP Right Cessation
- 1996-07-30 SK SK145-98A patent/SK14598A3/sk unknown
- 1996-07-30 AU AU66223/96A patent/AU720353B2/en not_active Ceased
- 1996-07-30 KR KR1019980700778A patent/KR100502770B1/ko not_active IP Right Cessation
- 1996-07-30 NZ NZ313696A patent/NZ313696A/xx unknown
- 1996-07-30 WO PCT/GB1996/001810 patent/WO1997006138A1/fr not_active Application Discontinuation
- 1996-07-30 JP JP9508201A patent/JPH11510178A/ja not_active Ceased
- 1996-07-30 CA CA002226671A patent/CA2226671C/fr not_active Expired - Fee Related
- 1996-07-30 CZ CZ1998309A patent/CZ293694B6/cs not_active IP Right Cessation
- 1996-07-30 MX MX9800946A patent/MX9800946A/es not_active IP Right Cessation
- 1996-07-30 US US09/011,135 patent/US6232338B1/en not_active Expired - Fee Related
- 1996-07-30 BR BR9609701A patent/BR9609701A/pt not_active Application Discontinuation
- 1996-07-30 TR TR2001/01884T patent/TR200101884T2/xx unknown
- 1996-07-30 EP EP96925855A patent/EP0842151A1/fr not_active Withdrawn
- 1996-07-30 HU HU9802857A patent/HUP9802857A3/hu unknown
- 1996-07-30 CN CN96197206A patent/CN1101380C/zh not_active Expired - Fee Related
- 1996-08-02 ZA ZA9606610A patent/ZA966610B/xx unknown
- 1996-08-02 MY MYPI96003186A patent/MY141457A/en unknown
-
1998
- 1998-02-03 NO NO19980467A patent/NO316624B1/no unknown
-
2000
- 2000-11-30 US US09/725,964 patent/US6541491B1/en not_active Expired - Fee Related
-
2002
- 2002-03-26 CN CN02108502A patent/CN1377647A/zh active Pending
- 2002-10-15 NO NO20024950A patent/NO20024950D0/no not_active Application Discontinuation
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