NO980467L - 4-mercaptopyrrolidin-derivater som farnesyl-transerase-inhibitorer - Google Patents
4-mercaptopyrrolidin-derivater som farnesyl-transerase-inhibitorerInfo
- Publication number
- NO980467L NO980467L NO980467A NO980467A NO980467L NO 980467 L NO980467 L NO 980467L NO 980467 A NO980467 A NO 980467A NO 980467 A NO980467 A NO 980467A NO 980467 L NO980467 L NO 980467L
- Authority
- NO
- Norway
- Prior art keywords
- transerase
- farnesyl
- inhibitors
- mercaptopyrrolidine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515975.2A GB9515975D0 (en) | 1995-08-04 | 1995-08-04 | Chemical compounds |
| PCT/GB1996/001810 WO1997006138A1 (en) | 1995-08-04 | 1996-07-30 | 4-mercaptopyrrolidine derivatives as farnesyl transferase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO980467D0 NO980467D0 (no) | 1998-02-03 |
| NO980467L true NO980467L (no) | 1998-04-03 |
| NO316624B1 NO316624B1 (no) | 2004-03-15 |
Family
ID=10778742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19980467A NO316624B1 (no) | 1995-08-04 | 1998-02-03 | 4-mercaptopyrrolidinderivater, anvendelse og fremstilling derav, samt farmasoytisk preparat |
| NO20024950A NO20024950D0 (no) | 1995-08-04 | 2002-10-15 | 4-Merkaptopyrrolidinderivater som farnesyltransferaseinhibitorer |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20024950A NO20024950D0 (no) | 1995-08-04 | 2002-10-15 | 4-Merkaptopyrrolidinderivater som farnesyltransferaseinhibitorer |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6232338B1 (no) |
| EP (1) | EP0842151A1 (no) |
| JP (1) | JPH11510178A (no) |
| KR (1) | KR100502770B1 (no) |
| CN (2) | CN1101380C (no) |
| AU (1) | AU720353B2 (no) |
| BR (1) | BR9609701A (no) |
| CA (1) | CA2226671C (no) |
| CZ (1) | CZ293694B6 (no) |
| GB (1) | GB9515975D0 (no) |
| HU (1) | HUP9802857A3 (no) |
| IL (1) | IL123155A0 (no) |
| MX (1) | MX9800946A (no) |
| MY (1) | MY141457A (no) |
| NO (2) | NO316624B1 (no) |
| NZ (1) | NZ313696A (no) |
| PL (1) | PL190873B1 (no) |
| RU (1) | RU2191773C2 (no) |
| SK (1) | SK14598A3 (no) |
| TR (2) | TR199800147T1 (no) |
| TW (1) | TW345575B (no) |
| WO (1) | WO1997006138A1 (no) |
| ZA (1) | ZA966610B (no) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204293B1 (en) | 1995-11-06 | 2001-03-20 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6221865B1 (en) | 1995-11-06 | 2001-04-24 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6693123B2 (en) | 1995-11-06 | 2004-02-17 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6310095B1 (en) | 1995-11-06 | 2001-10-30 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| AU4020897A (en) * | 1996-08-17 | 1998-03-06 | Zeneca Limited | 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors |
| CA2288330C (en) | 1997-05-07 | 2014-02-11 | University Of Pittsburgh | Benzoyl amino acid derivatives useful as inhibitors of protein isoprenyl tranferases |
| DE69801590T2 (de) | 1997-10-22 | 2002-07-11 | Astrazeneca Ab | Imidazolderivate und ihre verwendung als farnesylproteintransferase inhibitoren |
| EP1025089A1 (en) | 1997-10-22 | 2000-08-09 | Zeneca Limited | Imidazole derivatives and their use as farnesyl protein transferase inhibitors |
| EP1054865A1 (en) * | 1998-02-10 | 2000-11-29 | AstraZeneca UK Limited | Farnesyl transferase inhibitors |
| GB9930317D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| GB9930318D0 (en) * | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
| ITRM20020016A1 (it) * | 2002-01-15 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| CA2497628A1 (en) * | 2002-09-05 | 2004-03-18 | Medimmune, Inc. | Methods of preventing or treating cell malignancies by administering cd2 antagonists |
| US8034831B2 (en) * | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| US7563810B2 (en) * | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| KR101224235B1 (ko) | 2003-04-11 | 2013-01-25 | 메디뮨 엘엘씨 | 재조합 ｉｌ９ 항체 및 그의 용도 |
| US20060228350A1 (en) * | 2003-08-18 | 2006-10-12 | Medimmune, Inc. | Framework-shuffling of antibodies |
| EP2272566A3 (en) | 2003-08-18 | 2013-01-02 | MedImmune, LLC | Humanisation of antibodies |
| MXPA06002964A (es) | 2003-09-16 | 2006-06-14 | Astrazeneca Ab | Derivados de quinazolina como inhibidores de cinasa de tirosina. |
| US20070293539A1 (en) * | 2004-03-18 | 2007-12-20 | Lansbury Peter T | Methods for the treatment of synucleinopathies |
| WO2005089504A2 (en) * | 2004-03-18 | 2005-09-29 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies |
| JP2007529555A (ja) * | 2004-03-18 | 2007-10-25 | ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド | シヌクレイノパチーを治療する方法 |
| US20050272722A1 (en) * | 2004-03-18 | 2005-12-08 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies |
| EP1744751A4 (en) * | 2004-03-18 | 2010-03-10 | Brigham & Womens Hospital | TREATMENT OF SYNUCLEINOPATHIES |
| AU2005299355A1 (en) | 2004-10-27 | 2006-05-04 | Medimmune, Llc | Modulation of antibody specificity by tailoring the affinity to cognate antigens |
| WO2006102095A2 (en) | 2005-03-18 | 2006-09-28 | Medimmune, Inc. | Framework-shuffling of antibodies |
| AU2006261920A1 (en) | 2005-06-23 | 2007-01-04 | Medimmune, Llc | Antibody formulations having optimized aggregation and fragmentation profiles |
| US20110136867A1 (en) * | 2006-02-02 | 2011-06-09 | Justman Craig J | Treatment of Synucleinopathies |
| PL2292663T3 (pl) | 2006-08-28 | 2014-03-31 | Kyowa Hakko Kirin Co Ltd | Antagonistyczne ludzkie przeciwciała monoklonalne swoiste wobec ludzkiego LIGHT |
| EP2068923A4 (en) | 2007-03-30 | 2010-11-24 | Medimmune Llc | ANTIBODIES HAVING REDUCED DEAMIDATION PROFILES |
| CN101376656A (zh) * | 2007-08-30 | 2009-03-04 | 山东轩竹医药科技有限公司 | 培南衍生物 |
| AU2008319298B2 (en) | 2007-10-31 | 2014-07-31 | Medimmune, Llc | Protein scaffolds |
| US8232402B2 (en) * | 2008-03-12 | 2012-07-31 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
| MX2011005096A (es) * | 2008-11-13 | 2011-11-18 | Link Medicine Corp | Derivados de azaquinolinona y usos de los mismos. |
| US20100331363A1 (en) * | 2008-11-13 | 2010-12-30 | Link Medicine Corporation | Treatment of mitochondrial disorders using a farnesyl transferase inhibitor |
| US20110060005A1 (en) * | 2008-11-13 | 2011-03-10 | Link Medicine Corporation | Treatment of mitochondrial disorders using a farnesyl transferase inhibitor |
| CN102448458B (zh) | 2009-03-18 | 2015-07-22 | 小利兰·斯坦福大学理事会 | 治疗黄病毒科病毒感染的方法和组合物 |
| WO2012103165A2 (en) | 2011-01-26 | 2012-08-02 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies and uses thereof |
| CN103459437B (zh) * | 2011-03-30 | 2015-06-03 | 佳能株式会社 | 可聚合单体、高分子化合物、包含高分子化合物的电荷控制剂以及包含电荷控制剂的显影剂承载构件和调色剂 |
| KR102268351B1 (ko) | 2012-07-25 | 2021-06-22 | 셀덱스 쎄라퓨틱스, 인크. | 항-kit 항체 및 그의 용도 |
| AU2013329311A1 (en) | 2012-10-09 | 2015-04-30 | Igenica Biotherapeutics, Inc. | Anti-C16orf54 antibodies and methods of use thereof |
| AU2014274660B2 (en) | 2013-06-06 | 2019-05-16 | Pierre Fabre Médicament | Anti-C10orf54 antibodies and uses thereof |
| WO2015053871A2 (en) | 2013-08-26 | 2015-04-16 | MabVax Therapeutics, Inc. | NUCLEIC ACIDS ENCODING HUMAN ANTIBODIES TO SIALYL-LEWISa |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| HUE055189T2 (hu) | 2014-06-04 | 2021-11-29 | Biontech Res And Development Inc | Humán monoklonális antitestek a GD2 ganglioziddal ellen |
| DK3229838T3 (da) | 2014-12-11 | 2020-10-19 | Pf Medicament | Anti-C10orf54-antistoffer og anvendelser deraf |
| CN114504652A (zh) | 2015-03-03 | 2022-05-17 | 科马布有限公司 | 抗体、用途和方法 |
| WO2017011323A1 (en) | 2015-07-10 | 2017-01-19 | University Of Maryland, Baltimore | Small molecule inhibitors of the mcl-1 oncoprotein and uses thereof |
| CN108925136B (zh) | 2015-12-02 | 2022-02-01 | 斯特赛恩斯公司 | 特异于糖基化的btla（b和t淋巴细胞衰减因子）的抗体 |
| CN109415437B (zh) | 2015-12-02 | 2022-02-01 | 斯特库伯株式会社 | 与btn1a1免疫特异性结合的抗体和分子及其治疗用途 |
| EP3534947A1 (en) | 2016-11-03 | 2019-09-11 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses & methods |
| US20200148768A1 (en) | 2017-05-31 | 2020-05-14 | Stcube & Co., Inc. | Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof |
| WO2018222685A1 (en) | 2017-05-31 | 2018-12-06 | Stcube & Co., Inc. | Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1 |
| CN110997724A (zh) | 2017-06-06 | 2020-04-10 | 斯特库伯株式会社 | 使用结合btn1a1或btn1a1-配体的抗体和分子治疗癌症的方法 |
| EP3694889A1 (en) | 2017-10-13 | 2020-08-19 | Boehringer Ingelheim International GmbH | Human antibodies to thomsen-nouvelle (tn) antigen |
| CN112740043A (zh) | 2018-07-20 | 2021-04-30 | 皮埃尔法布雷医药公司 | Vista受体 |
| GB201908453D0 (en) * | 2019-06-12 | 2019-07-24 | Enterprise Therapeutics Ltd | Compounds for treating respiratory disease |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1283906C (en) | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
| JPS60233076A (ja) | 1984-05-03 | 1985-11-19 | Sumitomo Chem Co Ltd | 新規なβ−ラクタム化合物およびその製造法 |
| EP0182213B1 (en) | 1984-11-08 | 1990-09-26 | Sumitomo Pharmaceuticals Company, Limited | Carbapenem compounds and production thereof |
| KR880006244A (ko) | 1986-11-24 | 1988-07-22 | 후지사와 도모 기찌 로 | 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법 |
| GB8921635D0 (en) | 1989-09-25 | 1989-11-08 | Fujisawa Pharmaceutical Co | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives |
| CA2036163C (en) | 1990-02-14 | 2001-06-19 | Makoto Sunagawa | Novel beta-lactam compounds and their production |
| AU646012B2 (en) | 1990-02-23 | 1994-02-03 | Sankyo Company Limited | Carbapenem derivatives having antibiotic activity, their preparation and their use |
| GB9107363D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| US6083917A (en) * | 1990-04-18 | 2000-07-04 | Board Of Regents, The University Of Texas System | Methods and compositions for the identification, characterization and inhibition of farnesyltransferase |
| US5185248A (en) | 1990-05-08 | 1993-02-09 | E. R. Squibb & Sons, Inc. | Farnesyl-protein transferase assay for identifying compounds that block neoplastic transformation |
| JPH0578360A (ja) | 1991-01-31 | 1993-03-30 | Banyu Pharmaceut Co Ltd | ２−［２−（スルフアモイルアルキル）ピロリジニルチオカルバペネム誘導体 |
| GB9107342D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| GB9107341D0 (en) | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| JP2559949B2 (ja) | 1991-06-04 | 1996-12-04 | 三共株式会社 | １−メチルカルバペネム誘導体 |
| JPH04368386A (ja) | 1991-06-18 | 1992-12-21 | Sankyo Co Ltd | １−メチルカルバペネム−３−カルボン酸の製造法 |
| US5360798A (en) | 1991-07-04 | 1994-11-01 | Shionogi Seiyaku Kabushiki Kaisha | Aminooxypyrrolidinylthiocarbapenem compounds |
| CA2080172A1 (en) | 1991-10-11 | 1993-04-12 | Scott A. Biller | Method for blocking neoplastic transformation of cells induced by ras oncogenes |
| JPH05239058A (ja) | 1991-12-17 | 1993-09-17 | Fujisawa Pharmaceut Co Ltd | ３−ピロリジニルチオ−１−アザビシクロ［３．２．０ヘプト−２−エン−２−カルボン酸化合物 |
| GB9202298D0 (en) | 1992-02-04 | 1992-03-18 | Ici Plc | Antibiotic compounds |
| HU218676B (hu) | 1992-03-11 | 2000-10-28 | Sankyo Co. Ltd. | Antimikrobiális karbapenemszármazékok, ilyen vegyületeket tartalmazó gyógyászati készítmények és eljárás ezek előállítására |
| CA2091309A1 (en) | 1992-03-26 | 1993-09-27 | Frederic H. Jung | Antibiotic compounds |
| GB9304156D0 (en) | 1992-03-26 | 1993-04-21 | Zeneca Ltd | Antibiotic compounds |
| EP0636133A1 (en) | 1992-04-13 | 1995-02-01 | Fujisawa Pharmaceutical Co., Ltd. | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents |
| CA2099818A1 (en) | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
| EP0581501B1 (en) | 1992-07-21 | 1998-09-09 | Zeneca Limited | Antibiotic carbapenem compounds |
| EP0581502B1 (en) | 1992-07-21 | 1998-10-21 | Zeneca Limited | Antibiotic carbapenem compounds |
| EP0590885B1 (en) | 1992-09-28 | 2000-03-15 | Zeneca Limited | Antibiotic carbapenem compounds |
| CA2106330A1 (en) | 1992-10-07 | 1994-04-08 | Patrice J. Siret | Antibiotic compounds |
| CA2118985A1 (en) | 1993-04-02 | 1994-10-03 | Dinesh V. Patel | Heterocyclic inhibitors of farnesyl protein transferase |
| EP0703905A1 (en) | 1993-06-18 | 1996-04-03 | Merck & Co. Inc. | Inhibitors of farnesyl-protein transferase |
| US5468733A (en) | 1993-09-30 | 1995-11-21 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| WO1995009001A1 (en) * | 1993-09-30 | 1995-04-06 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| HUT77406A (hu) | 1994-03-15 | 1998-04-28 | Eisai Co., Ltd., | 1-(4-Amino-5-tio-pent-2-en)-il oldalláncot tartalmazó peptidomimetikumok és az ezeket tartalmazó gyógyszerkészítmények |
| CA2155448A1 (en) * | 1994-08-11 | 1996-02-12 | Katerina Leftheris | Inhibitors of farnesyl protein transferase |
| US5571835A (en) * | 1994-09-29 | 1996-11-05 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| KR100429950B1 (ko) | 1995-07-31 | 2004-06-16 | 시오노기세이야쿠가부시키가이샤 | 포스포리파제에이2저해활성을갖는피롤리딘유도체 |
| JP3115285B2 (ja) | 1999-04-27 | 2000-12-04 | 徳光 中ノ瀬 | 合成樹脂体を利用した水上施設 |
-
1995
- 1995-08-04 GB GBGB9515975.2A patent/GB9515975D0/en active Pending
-
1996
- 1996-07-23 TW TW085108987A patent/TW345575B/zh active
- 1996-07-30 NZ NZ313696A patent/NZ313696A/xx unknown
- 1996-07-30 US US09/011,135 patent/US6232338B1/en not_active Expired - Fee Related
- 1996-07-30 PL PL324819A patent/PL190873B1/pl not_active IP Right Cessation
- 1996-07-30 WO PCT/GB1996/001810 patent/WO1997006138A1/en not_active Application Discontinuation
- 1996-07-30 BR BR9609701A patent/BR9609701A/pt not_active Application Discontinuation
- 1996-07-30 IL IL12315596A patent/IL123155A0/xx not_active IP Right Cessation
- 1996-07-30 KR KR1019980700778A patent/KR100502770B1/ko not_active IP Right Cessation
- 1996-07-30 RU RU98103393/04A patent/RU2191773C2/ru not_active IP Right Cessation
- 1996-07-30 TR TR1998/00147T patent/TR199800147T1/xx unknown
- 1996-07-30 EP EP96925855A patent/EP0842151A1/en not_active Withdrawn
- 1996-07-30 JP JP9508201A patent/JPH11510178A/ja not_active Ceased
- 1996-07-30 CN CN96197206A patent/CN1101380C/zh not_active Expired - Fee Related
- 1996-07-30 HU HU9802857A patent/HUP9802857A3/hu unknown
- 1996-07-30 CZ CZ1998309A patent/CZ293694B6/cs not_active IP Right Cessation
- 1996-07-30 TR TR2001/01884T patent/TR200101884T2/xx unknown
- 1996-07-30 CA CA002226671A patent/CA2226671C/en not_active Expired - Fee Related
- 1996-07-30 AU AU66223/96A patent/AU720353B2/en not_active Ceased
- 1996-07-30 SK SK145-98A patent/SK14598A3/sk unknown
- 1996-07-30 MX MX9800946A patent/MX9800946A/es not_active IP Right Cessation
- 1996-08-02 ZA ZA9606610A patent/ZA966610B/xx unknown
- 1996-08-02 MY MYPI96003186A patent/MY141457A/en unknown
-
1998
- 1998-02-03 NO NO19980467A patent/NO316624B1/no unknown
-
2000
- 2000-11-30 US US09/725,964 patent/US6541491B1/en not_active Expired - Fee Related
-
2002
- 2002-03-26 CN CN02108502A patent/CN1377647A/zh active Pending
- 2002-10-15 NO NO20024950A patent/NO20024950D0/no not_active Application Discontinuation
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| NO974457D0 (no) | Inhibitorer for farnesylproteintransferase | |
| FI944804A (fi) | Pyrimidinyyliasetamideja elastaasin estäjinä | |
| NO992821D0 (no) | Ketobenzamider som calpain-inhibitorer | |
| ATE215541T1 (de) | (imidazol-5-yl)methyl-2-chinolinoderivate als farnesyl protein transferase inhibitoren | |
| DE69611361D1 (de) | Chinazolin-derivate | |
| DE69522717D1 (de) | Chinazolinderivate | |
| DE69610698T2 (de) | Chinazolin-derivate | |
| ATE199150T1 (de) | Diphenylmethylenpiperidin-derivate | |
| DE69601527T2 (de) | Pyrrolylbenzimidazol-Derivate | |
| ATA100695A (de) | Prothrombin-derivate | |
| DK0747346T3 (da) | N-acyl-2-arylcyclopropylmethylaminderivater som melatonerge midler | |
| ATE240307T1 (de) | Diarylalkenylamin-derivate | |
| DE59607054D1 (de) | 4-Amino-benzoylguanidin-Derivate | |
| DE59610106D1 (de) | Fluorbenzylether-Derivate | |
| ATE225347T1 (de) | Aza-anthracyclinone-derivate | |
| NO20000094D0 (no) | 6-Azaurcilderivater som IL-5 inhibitorer | |
| DE69711081T2 (de) | Farnesyl transferase inhibitoren | |
| DE59607055D1 (de) | 4-Mercapto-benzoylguanidin-Derivate | |
| DE69620514D1 (de) | 5-aminoflavon-derivate |