SK12832002A3 - Deriváty 2-fenylpyrán-4-ónu - Google Patents

Deriváty 2-fenylpyrán-4-ónu Download PDF

Info

Publication number
SK12832002A3
SK12832002A3 SK1283-2002A SK12832002A SK12832002A3 SK 12832002 A3 SK12832002 A3 SK 12832002A3 SK 12832002 A SK12832002 A SK 12832002A SK 12832002 A3 SK12832002 A3 SK 12832002A3
Authority
SK
Slovakia
Prior art keywords
group
phenyl
alkyl
methanesulfonyl
formula
Prior art date
Application number
SK1283-2002A
Other languages
English (en)
Slovak (sk)
Inventor
Crespo Maria Isabel Crespo
Mayorga Juan Miguel Jimenez
Julia Josep Lluis Matallana
Gras Joan Feixas
Original Assignee
Almirall Prodesfarma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Ag filed Critical Almirall Prodesfarma Ag
Publication of SK12832002A3 publication Critical patent/SK12832002A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK1283-2002A 2000-03-16 2001-03-16 Deriváty 2-fenylpyrán-4-ónu SK12832002A3 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200000637 2000-03-16
PCT/EP2001/003042 WO2001068633A1 (en) 2000-03-16 2001-03-16 2-phenylpyran-4-one derivatives

Publications (1)

Publication Number Publication Date
SK12832002A3 true SK12832002A3 (sk) 2003-11-04

Family

ID=8492732

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1283-2002A SK12832002A3 (sk) 2000-03-16 2001-03-16 Deriváty 2-fenylpyrán-4-ónu

Country Status (27)

Country Link
US (1) US7354936B2 (xx)
EP (1) EP1263751B1 (xx)
JP (1) JP2003527389A (xx)
KR (1) KR20030005221A (xx)
CN (1) CN1429221A (xx)
AR (1) AR030410A1 (xx)
AT (1) ATE269316T1 (xx)
AU (1) AU2001254692A1 (xx)
BG (1) BG107101A (xx)
BR (1) BR0109252A (xx)
CA (1) CA2403149A1 (xx)
CZ (1) CZ20023058A3 (xx)
DE (1) DE60103859T2 (xx)
EE (1) EE200200528A (xx)
ES (1) ES2223830T3 (xx)
HK (1) HK1048117A1 (xx)
HU (1) HUP0301696A2 (xx)
IL (1) IL151598A0 (xx)
MX (1) MXPA02009016A (xx)
NO (1) NO20024393L (xx)
NZ (1) NZ521187A (xx)
PE (1) PE20011333A1 (xx)
PL (1) PL358062A1 (xx)
RU (1) RU2002127728A (xx)
SK (1) SK12832002A3 (xx)
WO (1) WO2001068633A1 (xx)
ZA (1) ZA200207184B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465509B2 (en) 2000-06-30 2002-10-15 Merck Frosst Canada & Co. Pyrones as inhibitors of cyclooxygenase-2
ES2213485B1 (es) * 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
CN102731456B (zh) * 2011-04-01 2014-07-09 华中科技大学 一种抗肿瘤化合物及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH524614A (de) 1969-12-31 1972-06-30 Ciba Geigy Ag Verfahren zur Herstellung von neuen Imidazolderivaten
US3901908A (en) 1970-12-28 1975-08-26 Ciba Geigy Corp 2-alkyl- and 2-cycloalkyl-4,5-bis-phenyl-imidazoles
US4304728A (en) 1979-04-05 1981-12-08 Lilly Industries Limited 6-Substituted pyranone compounds and their use as pharmaceuticals
IL59748A (en) 1979-04-05 1983-11-30 Lilly Industries Ltd 5-substituted pyranone derivatives,their production and pharmaceutical compositions containing them
US6048850A (en) 1992-09-22 2000-04-11 Young; Donald A. Method of inhibiting prostaglandin synthesis in a human host
WO1995014014A2 (en) * 1993-11-19 1995-05-26 Parke, Davis & Company Pyrone derivatives as protease inhibitors and antiviral agents
US5521213A (en) 1994-08-29 1996-05-28 Merck Frosst Canada, Inc. Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
US5541204A (en) 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
EA199700209A1 (ru) 1995-04-04 1998-04-30 Глаксо Груп Лимитед ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА
BR9813998A (pt) 1997-11-19 2000-09-26 Kowa Co Novos derivados de piridazina e produtos medicinais contendo os mesmos como ingredientes efetivos
TW587079B (en) * 1998-09-25 2004-05-11 Almirall Prodesfarma Ag 2-phenylpyran-4-one derivatives

Also Published As

Publication number Publication date
PL358062A1 (en) 2004-08-09
HK1048117A1 (zh) 2003-03-21
CA2403149A1 (en) 2001-09-20
BR0109252A (pt) 2002-12-24
EE200200528A (et) 2004-04-15
WO2001068633A1 (en) 2001-09-20
EP1263751B1 (en) 2004-06-16
DE60103859D1 (de) 2004-07-22
MXPA02009016A (es) 2004-10-15
JP2003527389A (ja) 2003-09-16
BG107101A (bg) 2003-07-31
HUP0301696A2 (hu) 2003-09-29
US20030232880A1 (en) 2003-12-18
AR030410A1 (es) 2003-08-20
RU2002127728A (ru) 2004-03-20
CN1429221A (zh) 2003-07-09
DE60103859T2 (de) 2005-07-21
PE20011333A1 (es) 2002-01-16
AU2001254692A1 (en) 2001-09-24
KR20030005221A (ko) 2003-01-17
US7354936B2 (en) 2008-04-08
EP1263751A1 (en) 2002-12-11
CZ20023058A3 (cs) 2004-01-14
NO20024393D0 (no) 2002-09-13
ZA200207184B (en) 2003-12-08
ES2223830T3 (es) 2005-03-01
ATE269316T1 (de) 2004-07-15
NZ521187A (en) 2004-03-26
NO20024393L (no) 2002-11-13
IL151598A0 (en) 2003-04-10

Similar Documents

Publication Publication Date Title
JP2001199954A (ja) Ｃｏｘ−２インヒビターとしての（メチルスルホニル）フェニル−２−（５ｈ）−フラノン類
EP1115716B1 (en) 2-phenylpyran-4-one derivatives
JPH09509159A (ja) 炎症の治療のための置換スピロ化合物
EP1263751B1 (en) 2-phenylpyran-4-one derivatives
US20060189684A1 (en) 3-Phenylfuran-2-one derivatives as cox-2 inhibitor
EP1592680B1 (en) 2-phenylpyran-4-one derivatives as selective cox-2 inhibitors
US20060229338A1 (en) 2,3'-bipyridines derivatives as selective cox-2 inhibitors
WO2003006451A1 (en) 4-phenylpyran-2-one derivatives

Legal Events

Date Code Title Description
FB9A Suspension of patent application procedure