SK110099A3 - Remedies for lymphocytic tumors, an antibody, chimeric antibody and modified antibody - Google Patents

Remedies for lymphocytic tumors, an antibody, chimeric antibody and modified antibody Download PDF

Info

Publication number
SK110099A3
SK110099A3 SK1100-99A SK110099A SK110099A3 SK 110099 A3 SK110099 A3 SK 110099A3 SK 110099 A SK110099 A SK 110099A SK 110099 A3 SK110099 A3 SK 110099A3
Authority
SK
Slovakia
Prior art keywords
antibody
cells
ser
ala
gly
Prior art date
Application number
SK1100-99A
Other languages
English (en)
Slovak (sk)
Inventor
Yasuo Koishihara
Yasushi Yoshimura
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of SK110099A3 publication Critical patent/SK110099A3/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061Blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
SK1100-99A 1997-02-12 1998-02-12 Remedies for lymphocytic tumors, an antibody, chimeric antibody and modified antibody SK110099A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4141097 1997-02-12
PCT/JP1998/000568 WO1998035698A1 (fr) 1997-02-12 1998-02-12 Remedes contre les tumeurs lymphocitaires

Publications (1)

Publication Number Publication Date
SK110099A3 true SK110099A3 (en) 2000-08-14

Family

ID=12607597

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1100-99A SK110099A3 (en) 1997-02-12 1998-02-12 Remedies for lymphocytic tumors, an antibody, chimeric antibody and modified antibody

Country Status (20)

Country Link
US (2) US6503510B2 (xx)
EP (1) EP0997152B1 (xx)
KR (2) KR20000070989A (xx)
CN (1) CN1191855C (xx)
AT (1) ATE297219T1 (xx)
AU (1) AU724133B2 (xx)
BR (1) BR9811094A (xx)
CA (1) CA2280875C (xx)
DE (1) DE69830492T2 (xx)
ES (1) ES2241114T3 (xx)
HK (1) HK1026368A1 (xx)
HU (1) HUP0001136A3 (xx)
IL (1) IL131381A0 (xx)
NO (1) NO993866L (xx)
PL (1) PL190065B1 (xx)
RU (1) RU2177805C2 (xx)
SK (1) SK110099A3 (xx)
TR (1) TR199901949T2 (xx)
UA (1) UA65561C2 (xx)
WO (1) WO1998035698A1 (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW442493B (en) * 1993-10-15 2001-06-23 Toshio Hirano A membrane protein polypeptide having pre-B cell growth-supporting ability and a gene thereof
UA76934C2 (en) * 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
WO1999043703A1 (fr) * 1998-02-25 1999-09-02 Chugai Seiyaku Kabushiki Kaisha Technique de dosage immunochimique de l'anticorps anti-hm1.24
CN1370076A (zh) * 1999-08-23 2002-09-18 中外制药株式会社 Hm1.24抗原的表达增强剂
WO2002057316A1 (fr) * 2000-12-28 2002-07-25 Kirin Beer Kabushiki Kaisha Nouvel anticorps monoclonal
JP3986439B2 (ja) 2001-02-07 2007-10-03 中外製薬株式会社 造血器腫瘍の治療剤
WO2002072615A1 (fr) 2001-03-09 2002-09-19 Chugai Seiyaku Kabushiki Kaisha Methode de purification de proteines
US7858330B2 (en) 2001-10-19 2010-12-28 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
US7888478B2 (en) * 2002-09-11 2011-02-15 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
US20050226869A1 (en) * 2001-10-19 2005-10-13 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
EP1475101B1 (en) 2002-02-14 2010-10-27 Chugai Seiyaku Kabushiki Kaisha Antibody-containing solution pharmaceuticals
US20030223998A1 (en) * 2002-02-27 2003-12-04 Lamb Lawrence S. Targeted immunotherapy of acute lymphoblastic leukemia (ALL)
US20080219974A1 (en) * 2002-03-01 2008-09-11 Bernett Matthew J Optimized antibodies that target hm1.24
WO2005014651A1 (ja) * 2003-08-11 2005-02-17 Chugai Seiyaku Kabushiki Kaisha 糖鎖改変抗hm1.24抗体
US8603481B2 (en) * 2003-10-10 2013-12-10 Chugai Seiyaku Kabushiki Kaisha Therapeutic agents for solid tumors
BRPI0518279A2 (pt) * 2004-10-26 2008-11-11 Chugai Pharmaceutical Co Ltd anticorpo antiglipicam 3 tendo cadeia de aÇécar modificada
US8329186B2 (en) 2004-12-20 2012-12-11 Isu Abxis Co., Ltd Treatment of inflammation using BST2 inhibitor
US20080299128A1 (en) 2006-06-20 2008-12-04 Myung Kim Effect of Bst2 on inflammation
CA2660795C (en) 2006-09-18 2014-11-18 Xencor, Inc. Optimized antibodies that target hm1.24
UA105760C2 (uk) 2007-10-16 2014-06-25 Ес-Бі-Ай Біотех Ко., Лтд. Антитіло проти bst2
TWI516501B (zh) 2008-09-12 2016-01-11 禮納特神經系統科學公司 Pcsk9拮抗劑類
US9123149B2 (en) * 2013-03-15 2015-09-01 Columbia Insurance Company Expert color system for color selection with color harmony and color emotion intelligence
CN107619443B (zh) * 2016-07-14 2020-08-14 深圳宾德生物技术有限公司 抗人和鼠cd317的单克隆抗体及其制备方法和应用
CN109748964B (zh) * 2017-11-01 2020-11-17 深圳宾德生物技术有限公司 CD317单链抗体317scFv、其编码序列及制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650150A (en) * 1990-11-09 1997-07-22 Gillies; Stephen D. Recombinant antibody cytokine fusion proteins
DE69229482T2 (de) 1991-04-25 1999-11-18 Chugai Seiyaku K.K., Tokio/Tokyo Rekombinierte humane antikörper gegen den humanen interleukin 6-rezeptor
TW442493B (en) 1993-10-15 2001-06-23 Toshio Hirano A membrane protein polypeptide having pre-B cell growth-supporting ability and a gene thereof
UA76934C2 (en) * 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
CA2282631A1 (en) * 1997-02-28 1998-09-03 Chugai Seiyaku Kabushiki Kaisha Lymphocyte activation inhibitors
CA2305712A1 (en) 1997-10-03 1999-04-15 Chugai Seiyaku Kabushiki Kaisha Natural humanized antibody
JP4346116B2 (ja) 1997-10-14 2009-10-21 中外製薬株式会社 リンパ球系腫瘍に対する抗体の作用増強剤

Also Published As

Publication number Publication date
AU724133B2 (en) 2000-09-14
US20020037288A1 (en) 2002-03-28
US6503510B2 (en) 2003-01-07
RU2177805C2 (ru) 2002-01-10
UA65561A (en) 2000-08-15
TR199901949T2 (xx) 2000-01-21
CA2280875A1 (en) 1998-08-20
US20030113334A1 (en) 2003-06-19
KR100655979B1 (ko) 2006-12-08
EP0997152A4 (en) 2001-04-18
KR20030097614A (ko) 2003-12-31
DE69830492D1 (de) 2005-07-14
HUP0001136A3 (en) 2002-02-28
NO993866D0 (no) 1999-08-11
ES2241114T3 (es) 2005-10-16
DE69830492T2 (de) 2006-03-16
PL335140A1 (en) 2000-04-10
ATE297219T1 (de) 2005-06-15
PL190065B1 (pl) 2005-10-31
KR20000070989A (ko) 2000-11-25
WO1998035698A1 (fr) 1998-08-20
HUP0001136A2 (hu) 2000-08-28
CN1191855C (zh) 2005-03-09
AU5956398A (en) 1998-09-08
BR9811094A (pt) 2000-07-18
EP0997152A1 (en) 2000-05-03
UA65561C2 (uk) 2004-04-15
CA2280875C (en) 2005-07-05
NO993866L (no) 1999-10-11
CN1250381A (zh) 2000-04-12
HK1026368A1 (en) 2000-12-15
EP0997152B1 (en) 2005-06-08
IL131381A0 (en) 2001-01-28

Similar Documents

Publication Publication Date Title
SK110099A3 (en) Remedies for lymphocytic tumors, an antibody, chimeric antibody and modified antibody
EP0923941B1 (en) Remedies for myeloma to be used together with nitrogen mustard antitumor agents
JP3992298B2 (ja) 天然ヒト型化抗体
CA2308007C (en) Enhancer for antibody to lymphocytic tumors
AU718463B2 (en) Inhibitor of lymphocyte activation
JP3886238B2 (ja) リンパ球系腫瘍の治療剤
CA2382587A1 (en) Hm1.24 antigen expression potentiators
US20020034507A1 (en) Inhibitor of lymphocyte activation
JPH10155494A (ja) 再構成ヒト抗hm1.24抗体
JP3552898B2 (ja) リンパ球の活性化抑制剤
CZ285499A3 (cs) Léčebné činidlo pro lymfatické nádory, protilátka, chimerní protilátka a pozměněná protilátka
JPH1192399A (ja) 骨髄腫治療剤
MXPA99007358A (en) Remedies for lymphocytic tumors
JP2003201299A (ja) リンパ球系腫瘍の治療剤
JP4522431B2 (ja) 造血器腫瘍の治療剤
JP2003299492A (ja) 再構成ヒト抗hm1.24抗体