SI9300267A - Novi peptidi, njihova priprava in uporaba za zdravljenje neoplasticnih bolezni - Google Patents

Novi peptidi, njihova priprava in uporaba za zdravljenje neoplasticnih bolezni Download PDF

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Publication number
SI9300267A
SI9300267A SI9300267A SI9300267A SI9300267A SI 9300267 A SI9300267 A SI 9300267A SI 9300267 A SI9300267 A SI 9300267A SI 9300267 A SI9300267 A SI 9300267A SI 9300267 A SI9300267 A SI 9300267A
Authority
SI
Slovenia
Prior art keywords
pro
val
xan
alkyl
alkoxy
Prior art date
Application number
SI9300267A
Other languages
English (en)
Slovenian (sl)
Inventor
Andreas Haupt
Franz Emling
Cynthia Romerdahl
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of SI9300267A publication Critical patent/SI9300267A/sl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SI9300267A 1992-05-20 1993-05-20 Novi peptidi, njihova priprava in uporaba za zdravljenje neoplasticnih bolezni SI9300267A (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88578892A 1992-05-20 1992-05-20
US98569692A 1992-11-25 1992-11-25

Publications (1)

Publication Number Publication Date
SI9300267A true SI9300267A (sl) 1993-12-31

Family

ID=27128772

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9300267A SI9300267A (sl) 1992-05-20 1993-05-20 Novi peptidi, njihova priprava in uporaba za zdravljenje neoplasticnih bolezni

Country Status (21)

Country Link
EP (1) EP0642530B1 (no)
JP (2) JP3523253B2 (no)
KR (1) KR100286242B1 (no)
CN (1) CN1065874C (no)
AT (1) ATE169637T1 (no)
AU (1) AU669710B2 (no)
CA (1) CA2136339C (no)
CZ (1) CZ292612B6 (no)
DE (1) DE69320339T2 (no)
DK (1) DK0642530T3 (no)
ES (1) ES2118955T3 (no)
FI (1) FI120692B (no)
HU (2) HUT71398A (no)
IL (1) IL105651A (no)
MX (1) MX9302927A (no)
NO (1) NO310465B1 (no)
NZ (1) NZ252147A (no)
RU (1) RU2116312C1 (no)
SI (1) SI9300267A (no)
UA (1) UA45304C2 (no)
WO (1) WO1993023424A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
DE4415997A1 (de) * 1994-05-06 1995-11-09 Basf Ag Neuer peptidischer Wirkstoff und dessen Herstellung
DE4415998A1 (de) * 1994-05-06 1995-11-09 Basf Ag Neue Tetrapeptide, ihre Herstellung Verwendung
DE19527574A1 (de) * 1995-07-28 1997-01-30 Basf Ag Verfahren zur Herstellung vona-(N,N-Dialkyl)-aminocaarbonsäureamiden
DE19527575A1 (de) * 1995-07-28 1997-01-30 Basf Ag Verfahren zur Herstellung von peptidischer Wirkstoffe
US5807984A (en) * 1995-11-09 1998-09-15 Basf Aktienegesellschaft Oligopeptides, the preparation and use thereof
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
AU775090B2 (en) * 1995-12-15 2004-07-15 Abbvie Deutschland Gmbh & Co Kg Antineoplastic peptides
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
US5741892A (en) * 1996-07-30 1998-04-21 Basf Aktiengesellschaft Pentapeptides as antitumor agents
US5939527A (en) * 1996-07-30 1999-08-17 Basf Aktiengesellschaft Tetrapeptides as antitumor agents
US5965537A (en) * 1997-03-10 1999-10-12 Basf Aktiengesellschaft Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
US6143721A (en) 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
WO1999015130A2 (en) * 1997-09-24 1999-04-01 ARIZONA BOARD OF REGENTS, actingon behalf of ARIZ ONA STATE UNIVERSITY Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
US6686445B1 (en) 1997-09-24 2004-02-03 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
US5985837A (en) * 1998-07-08 1999-11-16 Basf Aktiengesellschaft Dolastatin 15 derivatives
ATE415413T1 (de) 2002-07-15 2008-12-15 Univ Princeton Iap-bindende verbindungen
ATE412409T1 (de) 2003-11-24 2008-11-15 Teva Gyogyszergyar Zartkoeruee Verfahren zur reinigung von pravastatin
WO2023033129A1 (ja) 2021-09-03 2023-03-09 東レ株式会社 癌の治療及び/又は予防用医薬組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
ATE190983T1 (de) * 1991-08-09 2000-04-15 Teikoku Hormone Mfg Co Ltd Neue tetrapeptidderivate

Also Published As

Publication number Publication date
KR100286242B1 (ko) 2001-04-16
IL105651A0 (en) 1993-09-22
HU211745A9 (en) 1995-12-28
NO944419D0 (no) 1994-11-18
CN1065874C (zh) 2001-05-16
RU94046434A (ru) 1996-10-27
FI945416A0 (fi) 1994-11-17
AU669710B2 (en) 1996-06-20
CZ284394A3 (en) 1995-05-17
DK0642530T3 (da) 1998-10-26
CN1085563A (zh) 1994-04-20
EP0642530B1 (en) 1998-08-12
JPH07506580A (ja) 1995-07-20
HUT71398A (en) 1995-11-28
RU2116312C1 (ru) 1998-07-27
IL105651A (en) 1998-07-15
WO1993023424A1 (en) 1993-11-25
CA2136339A1 (en) 1993-11-25
NO944419L (no) 1995-01-09
EP0642530A1 (en) 1995-03-15
JP3523253B2 (ja) 2004-04-26
DE69320339T2 (de) 1998-12-17
NZ252147A (en) 1996-10-28
NO310465B1 (no) 2001-07-09
CZ292612B6 (cs) 2003-11-12
MX9302927A (es) 1993-11-01
FI945416A (fi) 1994-11-17
ES2118955T3 (es) 1998-10-01
DE69320339D1 (de) 1998-09-17
UA45304C2 (uk) 2002-04-15
ATE169637T1 (de) 1998-08-15
AU4066293A (en) 1993-12-13
FI120692B (fi) 2010-01-29
JP2004149538A (ja) 2004-05-27
CA2136339C (en) 2008-02-05

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PL178351B1 (pl) Nowe peptydy

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