SI9300191A - Novi amidoalkil- in imidoalkil-piperazini - Google Patents
Novi amidoalkil- in imidoalkil-piperazini Download PDFInfo
- Publication number
- SI9300191A SI9300191A SI9300191A SI9300191A SI9300191A SI 9300191 A SI9300191 A SI 9300191A SI 9300191 A SI9300191 A SI 9300191A SI 9300191 A SI9300191 A SI 9300191A SI 9300191 A SI9300191 A SI 9300191A
- Authority
- SI
- Slovenia
- Prior art keywords
- group
- hydrogen atom
- same meaning
- piperazine
- optionally substituted
- Prior art date
Links
- 0 Nc(c(C(F)(F)F)c1)ccc1N1CCN(*N(C(c2ccccc22)=O)C2=O)CC1 Chemical compound Nc(c(C(F)(F)F)c1)ccc1N1CCN(*N(C(c2ccccc22)=O)C2=O)CC1 0.000 description 1
- GDJPJZIXLBOELX-UHFFFAOYSA-N Nc(cc1)c(C(F)(F)F)cc1N1CCN(CCCCN(C(CC2(CCCC2)C2)=O)C2=O)CC1 Chemical compound Nc(cc1)c(C(F)(F)F)cc1N1CCN(CCCCN(C(CC2(CCCC2)C2)=O)C2=O)CC1 GDJPJZIXLBOELX-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
- C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9201138A SE9201138D0 (sv) | 1992-04-09 | 1992-04-09 | Novel phthalimidoalkylpiperazines |
CN93118820A CN1099752A (zh) | 1992-04-09 | 1993-08-31 | 新型酰氨烷基-和亚氨烷基-哌嗪 |
Publications (1)
Publication Number | Publication Date |
---|---|
SI9300191A true SI9300191A (sl) | 1993-12-31 |
Family
ID=36869961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9300191A SI9300191A (sl) | 1992-04-09 | 1993-04-09 | Novi amidoalkil- in imidoalkil-piperazini |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0594813A1 (fi) |
JP (1) | JPH06508378A (fi) |
CN (1) | CN1099752A (fi) |
AU (1) | AU665825B2 (fi) |
BG (1) | BG98281A (fi) |
CA (1) | CA2109816A1 (fi) |
CZ (1) | CZ270193A3 (fi) |
FI (1) | FI935494A0 (fi) |
HU (1) | HUT68891A (fi) |
NO (2) | NO180794C (fi) |
SE (1) | SE9201138D0 (fi) |
SI (1) | SI9300191A (fi) |
SK (1) | SK138993A3 (fi) |
WO (1) | WO1993021179A1 (fi) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
US5395835A (en) * | 1994-03-24 | 1995-03-07 | Warner-Lambert Company | Naphthalamides as central nervous system agents |
GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
FR2742149B1 (fr) * | 1995-12-11 | 1998-02-13 | Inst Nat Sante Rech Med | Nouveaux derives de 2-naphtamides et leurs applications therapeutiques |
US5763609A (en) | 1996-03-21 | 1998-06-09 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of gaba brain receptor ligands |
US5703235A (en) | 1996-03-21 | 1997-12-30 | Neurogen Corporation | N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor subtype specific ligands |
ES2188936T3 (es) * | 1996-04-05 | 2003-07-01 | Sod Conseils Rech Applic | Antagonistas del receptor alfa-q-adrenergico. |
HUP0103987A3 (en) * | 2001-09-28 | 2004-11-29 | Richter Gedeon Vegyeszet | Phenylpiperazinylalkyl carboxylic acid amid derivatives, process for their preparation, pharmaceutical compositions containing them and their intermediates |
HU227543B1 (en) * | 2001-09-28 | 2011-08-29 | Richter Gedeon Nyrt | N-[4-(2-piperazin- and 2-piperidin-1-yl-ethyl)-cyclohexyl]-sulfon- and sulfamides, process for their preparation, their use and pharmaceutical compositions containing them |
DK1519726T3 (da) * | 2002-07-04 | 2007-06-04 | Sanol Arznei Schwarz Gmbh | Heteroarencarboxamider til anvendelse som dopamin-D3-ligander til behandling af CNS-sygdomme |
CN1948298B (zh) * | 2006-11-09 | 2010-09-01 | 东南大学 | 一种多巴胺d3受体部分激动剂及其应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3398151A (en) * | 1966-02-01 | 1968-08-20 | Mead Johnson & Co | Azaspirodecanediones and azaspiroundecanediones |
US3488352A (en) * | 1966-10-11 | 1970-01-06 | Shulton Inc | Basically substituted alkoxy anthranilamides,their corresponding 2-nitro compounds and derivatives thereof |
US3505338A (en) * | 1966-11-25 | 1970-04-07 | American Cyanamid Co | Thiophenecarbonylalkylene-diamines |
FR1537901A (fr) * | 1967-07-19 | 1968-08-30 | Bruneau & Cie Lab | Dérivés amidés d'acides halogéno et nitro benzoïques et leur préparation |
US3558777A (en) * | 1968-06-21 | 1971-01-26 | Mead Johnson & Co | Pharmacologic processes and compositions containing azaspirodecanediones and azaspiroundecanediones |
US3465080A (en) * | 1968-10-07 | 1969-09-02 | American Cyanamid Co | Therapeutic compositions containing morpholinoalkylene - indoles and methods of administering such in the treatment of depression |
JPS504650B2 (fi) * | 1971-09-03 | 1975-02-22 | ||
US3940397A (en) * | 1974-11-13 | 1976-02-24 | E. R. Squibb & Sons, Inc. | 2-[(Substituted-piperazinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones |
NL8005133A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met antiagressieve werking. |
US4361565A (en) * | 1981-12-28 | 1982-11-30 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines |
DE3529872A1 (de) * | 1985-08-21 | 1987-02-26 | Kali Chemie Pharma Gmbh | Neue tetraoxoverbindungen |
US4892943A (en) * | 1985-10-16 | 1990-01-09 | American Home Products Corporation | Fused bicyclic imides with psychotropic activity |
CA1340113C (en) * | 1988-05-24 | 1998-11-03 | Magid A. Abou-Gharbia | Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity |
DE68918832T2 (de) * | 1988-12-28 | 1995-02-09 | Suntory Ltd | Benzoxazepinderivate. |
US4939137A (en) * | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
CA2071897A1 (en) * | 1989-12-28 | 1991-06-29 | Richard A. Glennon | Sigma receptor ligands and the use thereof |
US5143923B1 (en) * | 1991-04-29 | 1993-11-02 | Hoechst-Roussel Pharmaceuticals Incorporated | Benzoisothiazole-and benzisoxazole-3-carboxamides |
IT1251144B (it) * | 1991-07-30 | 1995-05-04 | Boehringer Ingelheim Italia | Derivati del benzimidazolone |
-
1992
- 1992-04-09 SE SE9201138A patent/SE9201138D0/xx unknown
-
1993
- 1993-04-06 CZ CZ932701A patent/CZ270193A3/cs unknown
- 1993-04-06 SK SK1389-93A patent/SK138993A3/sk unknown
- 1993-04-06 CA CA002109816A patent/CA2109816A1/en not_active Abandoned
- 1993-04-06 EP EP93909109A patent/EP0594813A1/en not_active Withdrawn
- 1993-04-06 JP JP5518225A patent/JPH06508378A/ja active Pending
- 1993-04-06 AU AU39643/93A patent/AU665825B2/en not_active Ceased
- 1993-04-06 HU HU9303520A patent/HUT68891A/hu unknown
- 1993-04-06 WO PCT/SE1993/000295 patent/WO1993021179A1/en not_active Application Discontinuation
- 1993-04-09 SI SI9300191A patent/SI9300191A/sl unknown
- 1993-08-31 CN CN93118820A patent/CN1099752A/zh active Pending
- 1993-12-06 NO NO934426A patent/NO180794C/no unknown
- 1993-12-06 NO NO934426D patent/NO934426D0/no unknown
- 1993-12-08 BG BG98281A patent/BG98281A/xx unknown
- 1993-12-08 FI FI935494A patent/FI935494A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CZ270193A3 (en) | 1994-08-17 |
FI935494A (fi) | 1993-12-08 |
SE9201138D0 (sv) | 1992-04-09 |
NO934426D0 (no) | 1993-12-06 |
WO1993021179A1 (en) | 1993-10-28 |
FI935494A0 (fi) | 1993-12-08 |
NO934426L (no) | 1993-12-06 |
CA2109816A1 (en) | 1993-10-28 |
AU3964393A (en) | 1993-11-18 |
EP0594813A1 (en) | 1994-05-04 |
JPH06508378A (ja) | 1994-09-22 |
AU665825B2 (en) | 1996-01-18 |
NO180794C (no) | 1997-06-25 |
CN1099752A (zh) | 1995-03-08 |
HUT68891A (en) | 1995-08-28 |
SK138993A3 (en) | 1994-11-09 |
NO180794B (no) | 1997-03-17 |
BG98281A (en) | 1994-09-30 |
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