SE9201138D0 - Novel phthalimidoalkylpiperazines - Google Patents
Novel phthalimidoalkylpiperazinesInfo
- Publication number
- SE9201138D0 SE9201138D0 SE9201138A SE9201138A SE9201138D0 SE 9201138 D0 SE9201138 D0 SE 9201138D0 SE 9201138 A SE9201138 A SE 9201138A SE 9201138 A SE9201138 A SE 9201138A SE 9201138 D0 SE9201138 D0 SE 9201138D0
- Authority
- SE
- Sweden
- Prior art keywords
- group
- halogen
- hydrogen
- hydrogen atom
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
- C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9201138A SE9201138D0 (sv) | 1992-04-09 | 1992-04-09 | Novel phthalimidoalkylpiperazines |
IS4135A IS4135A (is) | 1992-04-09 | 1993-02-23 | Ný alkýlamíð- og alkýlimíð-piperasín |
IS3989A IS3989A (is) | 1992-04-09 | 1993-03-24 | Ný alkýlamíð- og alkýlimíð-piperasín |
EP93909109A EP0594813A1 (en) | 1992-04-09 | 1993-04-06 | Novel amidoalkyl- and imidoalkyl-piperazines |
PCT/SE1993/000295 WO1993021179A1 (en) | 1992-04-09 | 1993-04-06 | Novel amidoalkyl- and imidoalkyl-piperazines |
AU39643/93A AU665825B2 (en) | 1992-04-09 | 1993-04-06 | Novel amidoalkyl- and imidoalkyl-piperazines |
SK1389-93A SK138993A3 (en) | 1992-04-09 | 1993-04-06 | Amidoalkyl - and imidoalkylpiperazines |
CA002109816A CA2109816A1 (en) | 1992-04-09 | 1993-04-06 | Novel amidoalkyl- and imidoalkyl-piperazines |
CZ932701A CZ270193A3 (en) | 1992-04-09 | 1993-04-06 | Novel amidoalkyl- and imidoalkyl piperazines |
HU9303520A HUT68891A (en) | 1992-04-09 | 1993-04-06 | Novel amidoalkyl- and imidoalkyl-piperazines |
JP5518225A JPH06508378A (ja) | 1992-04-09 | 1993-04-06 | 新規アミドアルキル−およびイミドアルキル−ピペラジン類 |
SI9300191A SI9300191A (sl) | 1992-04-09 | 1993-04-09 | Novi amidoalkil- in imidoalkil-piperazini |
TW82106752A TW252977B (xx) | 1992-04-09 | 1993-08-21 | |
CN93118820A CN1099752A (zh) | 1992-04-09 | 1993-08-31 | 新型酰氨烷基-和亚氨烷基-哌嗪 |
NO934426A NO180794C (no) | 1992-04-09 | 1993-12-06 | Nye amidoalkyl- og imidoalkylpiperaziner samt farmasöytisk preparat inneholdende slike forbindelser |
NO934426D NO934426D0 (no) | 1992-04-09 | 1993-12-06 | Nye amidoalkyl- og imidoalkylpipera-ziner |
BG98281A BG98281A (en) | 1992-04-09 | 1993-12-08 | Amidoalkyl- and imidoalkylpiperazines |
FI935494A FI935494A0 (fi) | 1992-04-09 | 1993-12-08 | Nya amidolakyl- och imidoalkylpiperaziner |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9201138A SE9201138D0 (sv) | 1992-04-09 | 1992-04-09 | Novel phthalimidoalkylpiperazines |
CN93118820A CN1099752A (zh) | 1992-04-09 | 1993-08-31 | 新型酰氨烷基-和亚氨烷基-哌嗪 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9201138D0 true SE9201138D0 (sv) | 1992-04-09 |
Family
ID=36869961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9201138A SE9201138D0 (sv) | 1992-04-09 | 1992-04-09 | Novel phthalimidoalkylpiperazines |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0594813A1 (xx) |
JP (1) | JPH06508378A (xx) |
CN (1) | CN1099752A (xx) |
AU (1) | AU665825B2 (xx) |
BG (1) | BG98281A (xx) |
CA (1) | CA2109816A1 (xx) |
CZ (1) | CZ270193A3 (xx) |
FI (1) | FI935494A0 (xx) |
HU (1) | HUT68891A (xx) |
NO (2) | NO934426D0 (xx) |
SE (1) | SE9201138D0 (xx) |
SI (1) | SI9300191A (xx) |
SK (1) | SK138993A3 (xx) |
WO (1) | WO1993021179A1 (xx) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
US5395835A (en) * | 1994-03-24 | 1995-03-07 | Warner-Lambert Company | Naphthalamides as central nervous system agents |
GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
FR2742149B1 (fr) * | 1995-12-11 | 1998-02-13 | Inst Nat Sante Rech Med | Nouveaux derives de 2-naphtamides et leurs applications therapeutiques |
US5763609A (en) | 1996-03-21 | 1998-06-09 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of gaba brain receptor ligands |
US5703235A (en) | 1996-03-21 | 1997-12-30 | Neurogen Corporation | N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor subtype specific ligands |
CZ315098A3 (cs) * | 1996-04-05 | 1999-04-14 | Société De Conseils De Recherches Et D'applications Scientifiques (S. C. R. A. S.) | Antagonisté alfa1-adrenergických receptorů |
HU227543B1 (en) | 2001-09-28 | 2011-08-29 | Richter Gedeon Nyrt | N-[4-(2-piperazin- and 2-piperidin-1-yl-ethyl)-cyclohexyl]-sulfon- and sulfamides, process for their preparation, their use and pharmaceutical compositions containing them |
HUP0103987A3 (en) * | 2001-09-28 | 2004-11-29 | Richter Gedeon Vegyeszet | Phenylpiperazinylalkyl carboxylic acid amid derivatives, process for their preparation, pharmaceutical compositions containing them and their intermediates |
CA2489396A1 (en) * | 2002-07-04 | 2004-01-15 | Schwarz Pharma Ag | Utilization of heteroarene carboxamide as dopamine-d3 ligands for the treatment of cns diseases |
CN1948298B (zh) * | 2006-11-09 | 2010-09-01 | 东南大学 | 一种多巴胺d3受体部分激动剂及其应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3398151A (en) * | 1966-02-01 | 1968-08-20 | Mead Johnson & Co | Azaspirodecanediones and azaspiroundecanediones |
US3488352A (en) * | 1966-10-11 | 1970-01-06 | Shulton Inc | Basically substituted alkoxy anthranilamides,their corresponding 2-nitro compounds and derivatives thereof |
US3505338A (en) * | 1966-11-25 | 1970-04-07 | American Cyanamid Co | Thiophenecarbonylalkylene-diamines |
FR1537901A (fr) * | 1967-07-19 | 1968-08-30 | Bruneau & Cie Lab | Dérivés amidés d'acides halogéno et nitro benzoïques et leur préparation |
US3558777A (en) * | 1968-06-21 | 1971-01-26 | Mead Johnson & Co | Pharmacologic processes and compositions containing azaspirodecanediones and azaspiroundecanediones |
US3465080A (en) * | 1968-10-07 | 1969-09-02 | American Cyanamid Co | Therapeutic compositions containing morpholinoalkylene - indoles and methods of administering such in the treatment of depression |
JPS504650B2 (xx) * | 1971-09-03 | 1975-02-22 | ||
US3940397A (en) * | 1974-11-13 | 1976-02-24 | E. R. Squibb & Sons, Inc. | 2-[(Substituted-piperazinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones |
NL8005133A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met antiagressieve werking. |
US4361565A (en) * | 1981-12-28 | 1982-11-30 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines |
DE3529872A1 (de) * | 1985-08-21 | 1987-02-26 | Kali Chemie Pharma Gmbh | Neue tetraoxoverbindungen |
US4892943A (en) * | 1985-10-16 | 1990-01-09 | American Home Products Corporation | Fused bicyclic imides with psychotropic activity |
IL90279A (en) * | 1988-05-24 | 1995-03-30 | American Home Prod | History of piperazinyl carboxamide, their preparation and the pharmaceutical preparations containing them |
US5071845A (en) * | 1988-12-28 | 1991-12-10 | Suntory Limited | Benzoxazepine derivative |
US4939137A (en) * | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
CA2071897A1 (en) * | 1989-12-28 | 1991-06-29 | Richard A. Glennon | Sigma receptor ligands and the use thereof |
US5143923B1 (en) * | 1991-04-29 | 1993-11-02 | Hoechst-Roussel Pharmaceuticals Incorporated | Benzoisothiazole-and benzisoxazole-3-carboxamides |
IT1251144B (it) * | 1991-07-30 | 1995-05-04 | Boehringer Ingelheim Italia | Derivati del benzimidazolone |
-
1992
- 1992-04-09 SE SE9201138A patent/SE9201138D0/xx unknown
-
1993
- 1993-04-06 CZ CZ932701A patent/CZ270193A3/cs unknown
- 1993-04-06 SK SK1389-93A patent/SK138993A3/sk unknown
- 1993-04-06 CA CA002109816A patent/CA2109816A1/en not_active Abandoned
- 1993-04-06 WO PCT/SE1993/000295 patent/WO1993021179A1/en not_active Application Discontinuation
- 1993-04-06 JP JP5518225A patent/JPH06508378A/ja active Pending
- 1993-04-06 EP EP93909109A patent/EP0594813A1/en not_active Withdrawn
- 1993-04-06 AU AU39643/93A patent/AU665825B2/en not_active Ceased
- 1993-04-06 HU HU9303520A patent/HUT68891A/hu unknown
- 1993-04-09 SI SI9300191A patent/SI9300191A/sl unknown
- 1993-08-31 CN CN93118820A patent/CN1099752A/zh active Pending
- 1993-12-06 NO NO934426D patent/NO934426D0/no unknown
- 1993-12-06 NO NO934426A patent/NO180794C/no unknown
- 1993-12-08 FI FI935494A patent/FI935494A0/fi not_active Application Discontinuation
- 1993-12-08 BG BG98281A patent/BG98281A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU3964393A (en) | 1993-11-18 |
CN1099752A (zh) | 1995-03-08 |
WO1993021179A1 (en) | 1993-10-28 |
NO934426L (no) | 1993-12-06 |
JPH06508378A (ja) | 1994-09-22 |
NO180794B (no) | 1997-03-17 |
AU665825B2 (en) | 1996-01-18 |
CA2109816A1 (en) | 1993-10-28 |
EP0594813A1 (en) | 1994-05-04 |
SK138993A3 (en) | 1994-11-09 |
CZ270193A3 (en) | 1994-08-17 |
SI9300191A (sl) | 1993-12-31 |
NO180794C (no) | 1997-06-25 |
NO934426D0 (no) | 1993-12-06 |
FI935494A (fi) | 1993-12-08 |
BG98281A (en) | 1994-09-30 |
FI935494A0 (fi) | 1993-12-08 |
HUT68891A (en) | 1995-08-28 |
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