SI9010493B - Postopek za izdelavo transdermalnega terapevtskega sistema s stopnjevano oddajo dejavne snovi - Google Patents

Postopek za izdelavo transdermalnega terapevtskega sistema s stopnjevano oddajo dejavne snovi Download PDF

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Publication number
SI9010493B
SI9010493B SI9010493A SI9010493A SI9010493B SI 9010493 B SI9010493 B SI 9010493B SI 9010493 A SI9010493 A SI 9010493A SI 9010493 A SI9010493 A SI 9010493A SI 9010493 B SI9010493 B SI 9010493B
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Slovenia
Prior art keywords
active substance
membrane
reservoir
emission
substances
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SI9010493A
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English (en)
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SI9010493A (sl
Inventor
Walter Mueller
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Lts Lohmann Therapie Systeme Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Lts Lohmann Therapie Systeme Gmbh & Co.Kg filed Critical Lts Lohmann Therapie Systeme Gmbh & Co.Kg
Publication of SI9010493A publication Critical patent/SI9010493A/sl
Publication of SI9010493B publication Critical patent/SI9010493B/sl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • External Artificial Organs (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (6)

  1. -1- Postopek za izdelavo transdermalnega terapevtskega sistema s stopnjevano oddajo dejavne snovi PATENTNI ZAHTEVKI 1. Postopek za izdelavo transdermalnega sistema za krmiljeno, stopnjevano dajanje dejavnih snovi na kožo z večjo začetno dozo in manjšo vzdrževalno dozo, ki je sestavljen iz od kože umaknjenega, za dejavno snov neprepustnega, zadnjega sloja, iz rezervoarja dejavne snovi, ki vzporedno s ploskvijo oddajanja vsebuje vsaj eno membrano, iz oprijemno-lepljive pritrdilne naprave za sistem na koži in v danem primeru iz ponovno odstranljivega varovalnega sloja, ki opcijsko prekriva ploskve sistema proti koži in najmanj ene membrane (13) nameščene vzporedno na razdalji od površine oddaje, pri čemer je membrana (13) integrirana v rezervoar (12,14),označen s tem, da je permeabilnost membrane (13), (23), (32), (53) za sproščajočo dejavno snov ali snovi (12), (22), (31), (52) enaka nič ali večja od nič in da je ta površina membrane (13), (23), (32), (53) manjša od površine oddaje rezervoarja dejavne snovi (12), (22), (31), (52).
  2. 2. Postopek po zahtevku 1, označen s tem, da se uporabita vsaj dve membrani kateri imata različno prepustnost za oddajanje določenih snovi, in od katerih ima vsaj ena manjšo površino od površine oddaje sistema.
  3. 3. Postopek po zahtevkih 1 in 2, označen s tem, da je membrana (53), ki ima manjšo površino od površine oddajanja sistema, nepropustna za oddajanje določenih snovi in je integrirana v rezervoar (52).
  4. 4. Postopek po zahtevkih 1 do 3, označen s tem, da uporabljeni rezervoar (12), (22), (32), (52) vsebuje dejavno snov/dejavne snovi v koncentraciji, ki ne presega koncentracije nasičenosti. -2-
  5. 5. Postopek po enem od predhodnih zahtevkov, označen s tem, da uporabljeni rezervoar (12), (32), (52) vsebuje dejavno snov/dejavne snovi v koncentraciji, ki presega koncentracijo nasičenosti.
  6. 6. Postopek po enem od predhodnih zahtevkov, označen s tem, da so deli, ki vsebujejo dejavno snov uporabljenega rezervoarja (12), (22), (32), (52), sestavljeni iz več slojev različne sestave.
SI9010493A 1989-03-15 1990-03-14 Postopek za izdelavo transdermalnega terapevtskega sistema s stopnjevano oddajo dejavne snovi SI9010493B (sl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3908431A DE3908431A1 (de) 1989-03-15 1989-03-15 Transdermales system mit gestufter wirkstoffabgabe und verwendung fuer die lokale oder systemische wirkstoffverabreichung

Publications (2)

Publication Number Publication Date
SI9010493A SI9010493A (sl) 1998-06-30
SI9010493B true SI9010493B (sl) 1999-02-28

Family

ID=6376396

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9010493A SI9010493B (sl) 1989-03-15 1990-03-14 Postopek za izdelavo transdermalnega terapevtskega sistema s stopnjevano oddajo dejavne snovi

Country Status (26)

Country Link
EP (1) EP0387693B1 (sl)
JP (1) JPH0693921B2 (sl)
KR (1) KR960005148B1 (sl)
AT (1) ATE143276T1 (sl)
AU (1) AU625402B2 (sl)
CA (1) CA2012123C (sl)
CZ (1) CZ284770B6 (sl)
DD (1) DD292383A5 (sl)
DE (2) DE3908431A1 (sl)
DK (1) DK0387693T3 (sl)
ES (1) ES2095216T3 (sl)
FI (1) FI901290A0 (sl)
GR (1) GR3022033T3 (sl)
HR (1) HRP930662A2 (sl)
HU (1) HU206991B (sl)
IL (1) IL93678A (sl)
MY (1) MY107420A (sl)
NO (1) NO300087B1 (sl)
NZ (1) NZ232895A (sl)
PH (1) PH26276A (sl)
PL (1) PL162693B1 (sl)
PT (1) PT93430B (sl)
SI (1) SI9010493B (sl)
SK (1) SK279357B6 (sl)
YU (1) YU48228B (sl)
ZA (1) ZA901941B (sl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4341444C2 (de) * 1993-12-04 1996-03-14 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster und Verfahren zu seiner Herstellung
AU3512595A (en) * 1994-09-13 1996-03-29 Magainin Pharmaceuticals, Inc. Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds
US5714162A (en) * 1994-09-16 1998-02-03 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Scopolamine patch
DE4438989C2 (de) * 1994-09-16 1999-02-25 Lohmann Therapie Syst Lts Scopolaminpflaster
DE19705138A1 (de) * 1997-02-11 1998-08-13 Lohmann Therapie Syst Lts Dehnbares transdermales therapeutisches System
DE19733981A1 (de) * 1997-08-06 1999-02-11 Lohmann Therapie Syst Lts Transdermales Therapeutisches System (TTS) zur Abgabe von Wirkstoff durch die Haut an einen Organismus und Verfahren zur Applikation auf der Haut
DE19738643C2 (de) * 1997-09-04 2001-10-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Scopolaminbase und Verfahren zu seiner Herstellung
DE10056012A1 (de) * 2000-11-11 2002-05-16 Beiersdorf Ag Flexible Barrierefolie für ein Trägermaterial für medizinische Zwecke
DE10056014A1 (de) * 2000-11-11 2002-05-16 Beiersdorf Ag Mehrschichtige Trägerkonstruktion für wirkstofhaltige Pflastersyteme
DE102004020463A1 (de) * 2004-04-26 2005-11-10 Grünenthal GmbH Wirkstoffabgabesystem aus einem wirkstoffhaltigen Pflaster und mindestens einem Wirkstoffabgaberegulierungsmittel
MX355295B (es) 2011-04-04 2018-04-12 Procter & Gamble Artículos para el cuidado personal.
US9763547B2 (en) 2011-08-15 2017-09-19 The Procter & Gamble Company Personal care articles having multi-zone compliant personal care compositions
CN104202987B (zh) 2011-08-15 2017-09-01 宝洁公司 个人护理方法
BR112015032340A2 (pt) 2013-06-27 2017-07-25 Procter & Gamble composições e artigos para cuidados pessoais
DE102018216244A1 (de) 2018-09-24 2020-03-26 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Barriereschicht

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5755157A (en) * 1980-09-19 1982-04-01 Nitto Electric Ind Co Drug member having transcataneous absorbing property
IE53703B1 (en) * 1982-12-13 1989-01-18 Elan Corp Plc Drug delivery device
US4698062A (en) * 1985-10-30 1987-10-06 Alza Corporation Medical device for pulsatile transdermal delivery of biologically active agents
US4666441A (en) * 1985-12-17 1987-05-19 Ciba-Geigy Corporation Multicompartmentalized transdermal patches
DE3634016A1 (de) * 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung
DE3775830D1 (de) * 1986-06-13 1992-02-20 Alza Corp Aktivierung eines transdermalen drogenabgabesystems durch feuchtigkeit.
US4781924A (en) * 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device

Also Published As

Publication number Publication date
NO300087B1 (no) 1997-04-07
NO901128D0 (no) 1990-03-09
HUT53816A (en) 1990-12-28
HU901422D0 (en) 1990-06-28
CA2012123C (en) 1997-05-20
KR960005148B1 (ko) 1996-04-22
PT93430B (pt) 1996-06-28
EP0387693B1 (de) 1996-09-25
PH26276A (en) 1992-04-10
SK279357B6 (sk) 1998-10-07
JPH0693921B2 (ja) 1994-11-24
DD292383A5 (de) 1991-08-01
GR3022033T3 (en) 1997-03-31
PT93430A (pt) 1990-11-07
ZA901941B (en) 1990-12-28
HRP930662A2 (en) 1994-10-31
DK0387693T3 (da) 1997-03-17
FI901290A0 (fi) 1990-03-15
CS9001136A2 (en) 1991-11-12
YU48228B (sh) 1997-08-22
IL93678A (en) 1995-01-24
MY107420A (en) 1995-12-30
PL162693B1 (en) 1993-12-31
EP0387693A2 (de) 1990-09-19
IL93678A0 (en) 1990-12-23
NO901128L (no) 1990-09-17
DE3908431A1 (de) 1990-09-27
KR900013993A (ko) 1990-10-22
SI9010493A (sl) 1998-06-30
YU49390A (sh) 1992-07-20
EP0387693A3 (de) 1990-12-19
DE59010514D1 (de) 1996-10-31
CZ284770B6 (cs) 1999-02-17
HU206991B (en) 1993-03-01
DE3908431C2 (sl) 1991-07-04
CA2012123A1 (en) 1990-09-15
AU625402B2 (en) 1992-07-09
JPH0316571A (ja) 1991-01-24
ATE143276T1 (de) 1996-10-15
AU5076590A (en) 1990-09-20
ES2095216T3 (es) 1997-02-16
NZ232895A (en) 1991-09-25

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