SI9010455B - Novi kompleksi oziroma kelati antibiotikov z dvovalentnimi in/ali trovalentnimi kovinami in postopki za njihovo pripravo - Google Patents
Novi kompleksi oziroma kelati antibiotikov z dvovalentnimi in/ali trovalentnimi kovinami in postopki za njihovo pripravo Download PDFInfo
- Publication number
- SI9010455B SI9010455B SI9010455A SI9010455A SI9010455B SI 9010455 B SI9010455 B SI 9010455B SI 9010455 A SI9010455 A SI 9010455A SI 9010455 A SI9010455 A SI 9010455A SI 9010455 B SI9010455 B SI 9010455B
- Authority
- SI
- Slovenia
- Prior art keywords
- azithromycin
- chelates
- complexes
- complex
- valent
- Prior art date
Links
- 229910052751 metal Inorganic materials 0.000 title claims abstract description 9
- 239000002184 metal Substances 0.000 title claims abstract description 9
- 150000002739 metals Chemical class 0.000 title claims abstract description 8
- 239000003242 anti bacterial agent Substances 0.000 title claims abstract description 5
- 229940088710 antibiotic agent Drugs 0.000 title claims abstract description 5
- 238000000034 method Methods 0.000 title claims abstract description 4
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 claims abstract 12
- 229960004099 azithromycin Drugs 0.000 claims abstract 9
- 239000011777 magnesium Substances 0.000 claims 5
- 239000000499 gel Substances 0.000 claims 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- 239000013522 chelant Substances 0.000 claims 2
- MNQYNQBOVCBZIQ-JQOFMKNESA-A sucralfate Chemical compound O[Al](O)OS(=O)(=O)O[C@@H]1[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](COS(=O)(=O)O[Al](O)O)O[C@H]1O[C@@]1(COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)O1 MNQYNQBOVCBZIQ-JQOFMKNESA-A 0.000 claims 2
- 229960004291 sucralfate Drugs 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 229940008027 aluminum hydroxide / magnesium carbonate Drugs 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 1
- 150000001805 chlorine compounds Chemical class 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims 1
- 239000001095 magnesium carbonate Substances 0.000 claims 1
- 229910000000 metal hydroxide Inorganic materials 0.000 claims 1
- 150000004692 metal hydroxides Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| YU45590A YU45590A (sh) | 1990-03-07 | 1990-03-07 | Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SI9010455A SI9010455A (en) | 1997-08-31 |
| SI9010455B true SI9010455B (sl) | 2000-04-30 |
Family
ID=25550003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9010455A SI9010455B (sl) | 1990-03-07 | 1990-03-28 | Novi kompleksi oziroma kelati antibiotikov z dvovalentnimi in/ali trovalentnimi kovinami in postopki za njihovo pripravo |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5498699A (cs) |
| EP (1) | EP0445743B1 (cs) |
| JP (1) | JP2731636B2 (cs) |
| CN (2) | CN1041166C (cs) |
| AT (1) | ATE143266T1 (cs) |
| BG (1) | BG61230B1 (cs) |
| CA (1) | CA2037663C (cs) |
| CZ (1) | CZ280181B6 (cs) |
| DE (1) | DE69122282T2 (cs) |
| DK (1) | DK0445743T3 (cs) |
| ES (1) | ES2094763T3 (cs) |
| GR (1) | GR3021947T3 (cs) |
| HR (1) | HRP940256B1 (cs) |
| HU (2) | HU209455B (cs) |
| PL (1) | PL166279B1 (cs) |
| RO (1) | RO107660B1 (cs) |
| RU (2) | RU2039060C1 (cs) |
| SI (1) | SI9010455B (cs) |
| SK (1) | SK279278B6 (cs) |
| YU (1) | YU45590A (cs) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2064634C (en) * | 1991-04-04 | 1998-08-04 | James V. Heck | 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions |
| GB9120131D0 (en) * | 1991-09-20 | 1991-11-06 | Glaxo Group Ltd | Medicaments |
| TW271400B (cs) * | 1992-07-30 | 1996-03-01 | Pfizer | |
| GB9501560D0 (en) * | 1995-01-26 | 1995-03-15 | Nycomed Imaging As | Contrast agents |
| AU4493796A (en) * | 1995-01-26 | 1996-08-14 | Nycomed Imaging As | Bismuth compounds |
| US5900410A (en) * | 1996-08-27 | 1999-05-04 | Hartmann; John F. | Monotherapy of peptic ulcers and gastritis |
| US6861411B1 (en) * | 1997-12-02 | 2005-03-01 | Pfizer, Inc. | Method of treating eye infections with azithromycin |
| US7056893B2 (en) | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
| US6239113B1 (en) | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
| HRP20010301A2 (en) * | 2001-04-27 | 2001-12-31 | Pliva D D | New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases |
| EP1671978A1 (en) | 2001-05-22 | 2006-06-21 | Pfizer Products Inc. | New Cristal Form of Azithromycin |
| JP2005501862A (ja) * | 2001-08-21 | 2005-01-20 | ファイザー・プロダクツ・インク | １回限りの投与量のアジスロマイシン |
| RU2283116C2 (ru) * | 2002-05-27 | 2006-09-10 | Курский государственный медицинский университет | Способ увеличения выживаемости изолированного кожного лоскута "на ножке" у животных с пониженным антиоксидантным фоном |
| US7468428B2 (en) | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
| US20060046970A1 (en) * | 2004-08-31 | 2006-03-02 | Insite Vision Incorporated | Topical otic compositions and methods of topical treatment of prevention of otic infections |
| AU2005299294B2 (en) | 2004-10-25 | 2012-06-07 | Paratek Pharmaceuticals, Inc. | 4-aminotetracyclines and methods of use thereof |
| US8440646B1 (en) | 2006-10-11 | 2013-05-14 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of Bacillus anthracis infections |
| CN104892694A (zh) * | 2015-05-24 | 2015-09-09 | 广西师范学院 | 蔗糖硫酸酯铜类化合物及其制作方法和用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3862225A (en) * | 1961-08-18 | 1975-01-21 | Pfizer | D-ring substituted tetracyclines |
| US3622627A (en) * | 1967-09-13 | 1971-11-23 | Pfizer | 4-dedimethylaminatetracycline and 5a, 6-anhydro derivatives thereof |
| HU167946B (cs) * | 1973-04-16 | 1976-01-28 | ||
| YU43006B (en) * | 1981-03-06 | 1989-02-28 | Pliva Pharm & Chem Works | Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof |
| SG72632A1 (en) * | 1985-04-18 | 2000-05-23 | Procter & Gamble | Treatment of non-ulcer dyspepsia with bismuth salts |
| ATE81010T1 (de) * | 1985-06-13 | 1992-10-15 | Barry James Marshall | Zusammensetzungen zur behandlung von magendarmst¯rungen. |
| IT1200774B (it) * | 1985-10-10 | 1989-01-27 | Pierrel Spa | Procedimento di sentisi dell'amikacina |
| YU44599B (en) * | 1986-09-12 | 1990-10-31 | Pliva Pharm & Chem Works | Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals |
| DE3860503D1 (de) * | 1987-09-03 | 1990-10-04 | Pliva Pharm & Chem Works | 10-dihydro-10-deoxo-11-azaerythronolid-a-verbindungen,verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung in arzneimitteln und in deren herstellung. |
| US5196205A (en) * | 1987-10-12 | 1993-03-23 | Borody Thomas J | Method for treatment of gastro intestinal disorders |
| US5246708A (en) * | 1987-10-28 | 1993-09-21 | Pro-Neuron, Inc. | Methods for promoting wound healing with deoxyribonucleosides |
| DE391005T1 (de) * | 1989-04-03 | 1991-04-11 | Ranbaxy Laboratories, Ltd., New Delhi | Verfahren zur herstellung von alpha-6-deoxytetracyclinen. |
| US5348946A (en) * | 1991-02-28 | 1994-09-20 | Biochem Immunosystems, Inc. | Heteroanthracycline antitumor analogs |
| MA28714B1 (fr) * | 2005-12-15 | 2007-07-02 | Green Technlology Sarl | Une arabinogalactane proteine ayant la propriete d'absorber les graisses et le procede d'obtention de cette arabinogalactane proteine |
-
1990
- 1990-03-07 YU YU45590A patent/YU45590A/sh unknown
- 1990-03-28 SI SI9010455A patent/SI9010455B/sl unknown
-
1991
- 1991-03-05 DK DK91103336.3T patent/DK0445743T3/da active
- 1991-03-05 ES ES91103336T patent/ES2094763T3/es not_active Expired - Lifetime
- 1991-03-05 EP EP91103336A patent/EP0445743B1/en not_active Expired - Lifetime
- 1991-03-05 AT AT91103336T patent/ATE143266T1/de not_active IP Right Cessation
- 1991-03-05 DE DE69122282T patent/DE69122282T2/de not_active Expired - Fee Related
- 1991-03-06 CZ CS91587A patent/CZ280181B6/cs not_active IP Right Cessation
- 1991-03-06 CN CN91101355A patent/CN1041166C/zh not_active Expired - Fee Related
- 1991-03-06 BG BG93995A patent/BG61230B1/bg unknown
- 1991-03-06 RU SU914894967A patent/RU2039060C1/ru active
- 1991-03-06 US US08/022,398 patent/US5498699A/en not_active Expired - Fee Related
- 1991-03-06 CA CA002037663A patent/CA2037663C/en not_active Expired - Fee Related
- 1991-03-06 SK SK587-91A patent/SK279278B6/sk unknown
- 1991-03-06 RO RO147062A patent/RO107660B1/ro unknown
- 1991-03-07 HU HU91740A patent/HU209455B/hu not_active IP Right Cessation
- 1991-03-07 PL PL91289333A patent/PL166279B1/pl unknown
- 1991-03-07 JP JP3041832A patent/JP2731636B2/ja not_active Expired - Lifetime
-
1992
- 1992-04-23 RU SU925011653A patent/RU2039061C1/ru active
-
1994
- 1994-04-18 HR HRP-455/90A patent/HRP940256B1/xx not_active IP Right Cessation
-
1995
- 1995-06-30 HU HU95P/P00704P patent/HU211475A9/hu unknown
-
1996
- 1996-12-10 GR GR960403364T patent/GR3021947T3/el unknown
-
1997
- 1997-04-18 CN CN97109555A patent/CN1051560C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CZ280181B6 (cs) | 1995-11-15 |
| HUT56849A (en) | 1991-10-28 |
| EP0445743A2 (en) | 1991-09-11 |
| HU209455B (en) | 1994-06-28 |
| JP2731636B2 (ja) | 1998-03-25 |
| JPH06184186A (ja) | 1994-07-05 |
| DE69122282D1 (de) | 1996-10-31 |
| BG61230B1 (bg) | 1997-03-31 |
| GR3021947T3 (en) | 1997-03-31 |
| YU45590A (sh) | 1992-07-20 |
| HU211475A9 (en) | 1995-11-28 |
| CN1051560C (zh) | 2000-04-19 |
| EP0445743A3 (en) | 1992-10-07 |
| CS9100587A2 (en) | 1991-10-15 |
| RU2039060C1 (ru) | 1995-07-09 |
| CN1054534A (zh) | 1991-09-18 |
| CA2037663C (en) | 1999-01-19 |
| ATE143266T1 (de) | 1996-10-15 |
| EP0445743B1 (en) | 1996-09-25 |
| RU2039061C1 (ru) | 1995-07-09 |
| DE69122282T2 (de) | 1997-04-24 |
| CN1168891A (zh) | 1997-12-31 |
| SK279278B6 (sk) | 1998-09-09 |
| CN1041166C (zh) | 1998-12-16 |
| HRP940256A2 (en) | 1997-06-30 |
| US5498699A (en) | 1996-03-12 |
| RO107660B1 (ro) | 1993-12-30 |
| HU910740D0 (en) | 1991-09-30 |
| BG93995A (bg) | 1993-12-24 |
| DK0445743T3 (cs) | 1997-02-17 |
| CA2037663A1 (en) | 1991-09-08 |
| PL166279B1 (pl) | 1995-04-28 |
| SI9010455A (en) | 1997-08-31 |
| ES2094763T3 (es) | 1997-02-01 |
| HRP940256B1 (en) | 1998-10-31 |
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