HRP940256B1 - New complexes or antibiotic helates with two- and/or three- valent metals and processes for the preparation thereof - Google Patents

New complexes or antibiotic helates with two- and/or three- valent metals and processes for the preparation thereof

Info

Publication number
HRP940256B1
HRP940256B1 HRP-455/90A HRP940256A HRP940256B1 HR P940256 B1 HRP940256 B1 HR P940256B1 HR P940256 A HRP940256 A HR P940256A HR P940256 B1 HRP940256 B1 HR P940256B1
Authority
HR
Croatia
Prior art keywords
processes
helates
antibiotic
preparation
new complexes
Prior art date
Application number
HRP-455/90A
Other languages
English (en)
Inventor
Lidija Kolacni-Babic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Priority to HRP-455/90A priority Critical patent/HRP940256B1/xx
Publication of HRP940256A2 publication Critical patent/HRP940256A2/hr
Publication of HRP940256B1 publication Critical patent/HRP940256B1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HRP-455/90A 1990-03-07 1994-04-18 New complexes or antibiotic helates with two- and/or three- valent metals and processes for the preparation thereof HRP940256B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HRP-455/90A HRP940256B1 (en) 1990-03-07 1994-04-18 New complexes or antibiotic helates with two- and/or three- valent metals and processes for the preparation thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
YU45590A YU45590A (sh) 1990-03-07 1990-03-07 Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje
HRP-455/90A HRP940256B1 (en) 1990-03-07 1994-04-18 New complexes or antibiotic helates with two- and/or three- valent metals and processes for the preparation thereof

Publications (2)

Publication Number Publication Date
HRP940256A2 HRP940256A2 (en) 1997-06-30
HRP940256B1 true HRP940256B1 (en) 1998-10-31

Family

ID=25550003

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-455/90A HRP940256B1 (en) 1990-03-07 1994-04-18 New complexes or antibiotic helates with two- and/or three- valent metals and processes for the preparation thereof

Country Status (20)

Country Link
US (1) US5498699A (cs)
EP (1) EP0445743B1 (cs)
JP (1) JP2731636B2 (cs)
CN (2) CN1041166C (cs)
AT (1) ATE143266T1 (cs)
BG (1) BG61230B1 (cs)
CA (1) CA2037663C (cs)
CZ (1) CZ280181B6 (cs)
DE (1) DE69122282T2 (cs)
DK (1) DK0445743T3 (cs)
ES (1) ES2094763T3 (cs)
GR (1) GR3021947T3 (cs)
HR (1) HRP940256B1 (cs)
HU (2) HU209455B (cs)
PL (1) PL166279B1 (cs)
RO (1) RO107660B1 (cs)
RU (2) RU2039060C1 (cs)
SI (1) SI9010455B (cs)
SK (1) SK279278B6 (cs)
YU (1) YU45590A (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
GB9120131D0 (en) * 1991-09-20 1991-11-06 Glaxo Group Ltd Medicaments
TW271400B (cs) * 1992-07-30 1996-03-01 Pfizer
GB9501560D0 (en) * 1995-01-26 1995-03-15 Nycomed Imaging As Contrast agents
AU4493796A (en) * 1995-01-26 1996-08-14 Nycomed Imaging As Bismuth compounds
US5900410A (en) * 1996-08-27 1999-05-04 Hartmann; John F. Monotherapy of peptic ulcers and gastritis
US6861411B1 (en) * 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
HRP20010301A2 (en) * 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
EP1671978A1 (en) 2001-05-22 2006-06-21 Pfizer Products Inc. New Cristal Form of Azithromycin
JP2005501862A (ja) * 2001-08-21 2005-01-20 ファイザー・プロダクツ・インク 1回限りの投与量のアジスロマイシン
RU2283116C2 (ru) * 2002-05-27 2006-09-10 Курский государственный медицинский университет Способ увеличения выживаемости изолированного кожного лоскута "на ножке" у животных с пониженным антиоксидантным фоном
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
AU2005299294B2 (en) 2004-10-25 2012-06-07 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
CN104892694A (zh) * 2015-05-24 2015-09-09 广西师范学院 蔗糖硫酸酯铜类化合物及其制作方法和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862225A (en) * 1961-08-18 1975-01-21 Pfizer D-ring substituted tetracyclines
US3622627A (en) * 1967-09-13 1971-11-23 Pfizer 4-dedimethylaminatetracycline and 5a, 6-anhydro derivatives thereof
HU167946B (cs) * 1973-04-16 1976-01-28
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
SG72632A1 (en) * 1985-04-18 2000-05-23 Procter & Gamble Treatment of non-ulcer dyspepsia with bismuth salts
ATE81010T1 (de) * 1985-06-13 1992-10-15 Barry James Marshall Zusammensetzungen zur behandlung von magendarmst¯rungen.
IT1200774B (it) * 1985-10-10 1989-01-27 Pierrel Spa Procedimento di sentisi dell'amikacina
YU44599B (en) * 1986-09-12 1990-10-31 Pliva Pharm & Chem Works Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals
DE3860503D1 (de) * 1987-09-03 1990-10-04 Pliva Pharm & Chem Works 10-dihydro-10-deoxo-11-azaerythronolid-a-verbindungen,verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung in arzneimitteln und in deren herstellung.
US5196205A (en) * 1987-10-12 1993-03-23 Borody Thomas J Method for treatment of gastro intestinal disorders
US5246708A (en) * 1987-10-28 1993-09-21 Pro-Neuron, Inc. Methods for promoting wound healing with deoxyribonucleosides
DE391005T1 (de) * 1989-04-03 1991-04-11 Ranbaxy Laboratories, Ltd., New Delhi Verfahren zur herstellung von alpha-6-deoxytetracyclinen.
US5348946A (en) * 1991-02-28 1994-09-20 Biochem Immunosystems, Inc. Heteroanthracycline antitumor analogs
MA28714B1 (fr) * 2005-12-15 2007-07-02 Green Technlology Sarl Une arabinogalactane proteine ayant la propriete d'absorber les graisses et le procede d'obtention de cette arabinogalactane proteine

Also Published As

Publication number Publication date
CZ280181B6 (cs) 1995-11-15
HUT56849A (en) 1991-10-28
EP0445743A2 (en) 1991-09-11
HU209455B (en) 1994-06-28
JP2731636B2 (ja) 1998-03-25
JPH06184186A (ja) 1994-07-05
DE69122282D1 (de) 1996-10-31
BG61230B1 (bg) 1997-03-31
GR3021947T3 (en) 1997-03-31
YU45590A (sh) 1992-07-20
HU211475A9 (en) 1995-11-28
CN1051560C (zh) 2000-04-19
EP0445743A3 (en) 1992-10-07
CS9100587A2 (en) 1991-10-15
RU2039060C1 (ru) 1995-07-09
CN1054534A (zh) 1991-09-18
CA2037663C (en) 1999-01-19
ATE143266T1 (de) 1996-10-15
EP0445743B1 (en) 1996-09-25
RU2039061C1 (ru) 1995-07-09
DE69122282T2 (de) 1997-04-24
CN1168891A (zh) 1997-12-31
SK279278B6 (sk) 1998-09-09
SI9010455B (sl) 2000-04-30
CN1041166C (zh) 1998-12-16
HRP940256A2 (en) 1997-06-30
US5498699A (en) 1996-03-12
RO107660B1 (ro) 1993-12-30
HU910740D0 (en) 1991-09-30
BG93995A (bg) 1993-12-24
DK0445743T3 (cs) 1997-02-17
CA2037663A1 (en) 1991-09-08
PL166279B1 (pl) 1995-04-28
SI9010455A (en) 1997-08-31
ES2094763T3 (es) 1997-02-01

Similar Documents

Publication Publication Date Title
HRP940256B1 (en) New complexes or antibiotic helates with two- and/or three- valent metals and processes for the preparation thereof
UA27105A1 (uk) О-метильhі похідhі азитроміциhу а, що мають аhтибактеріальhу активhість, спосіб їх отримаhhя та проміжhі сполуки
AU8188987A (en) Improved metal complex-containing pharmaceutical agents
IL100942A0 (en) 2,4-diaminoquinazoline derivatives for enhancing antitumor activity
GEP20074095B (en) Analogs of human insulin modified at position 29 of the b chain thereof
FI972287A0 (fi) Uudenlaisia polysubstituoituja DTPA-johdoksia ja niiden metallikomplekseja, kyseisiä komplekseja sisältäviä farmaseuttisia aineita, niiden käyttö diagnosoinnissa ja terapiassa sekä menetelmiä kyseisten kompleksinmuodostajien ja kompleksien valmistamiseksi ja menetelmiä kyseisten.
IL97463A0 (en) Pharmaceutical composition for treating emotional numbness
IE863381L (en) Antibiotics
GB2239013B (en) Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same
DE69101105D1 (de) Cis-platin-komplexe mit chelatierenden aminen und sulfinylcarboxylaten.
EP0231111A3 (en) Glycopeptide antibiotics, their preparation and use and microorganisms for producing them
DE3468325D1 (en) Cytotoxic pharmaceutical association, especially suited for the treatment of cancers
IL87364A0 (en) Water-soluble antibiotic composition containing cephem derivatives and processes for the preparation thereof
PH30994A (en) Preparation of betaketoesters useful in preparing quinolone antibiotics.
AU1214892A (en) Amide-chelates, their metal complexes as well as their use in diagnosis and treatment
DE69011046D1 (de) Pyridinderivate, Verfahren zur Herstellung und pharmazeutische Zusammensetzungen.
ZA883975B (en) Treatment and diagnosis of footrot using the basic protease of b.nodosus
GB9001687D0 (en) Treatment of poisoning and composition for use therein
AU8174691A (en) Reducing chelating agents, their technetium and rhenium complexes, process for their production as well as their use in diagnosis and treatment
EP0248361A3 (en) Pharmaceutical preparation for the treatment of bacterial infections
GR3004570T3 (cs)
RU95120677A (ru) Способ лечения злокачественных опухолей
EP0481441A3 (en) Novel cephem compounds, their preparation processes and antibacterial agents
DE3376833D1 (en) Derivatives of 7-oxo-4-oxa-diazabicyclo-(3.2.0)-hept-2-en not substituted in position 6, processes for their preparation and their use as intermediates in the synthesis of beta-lactam antibiotics
AU1096992A (en) Antibacterial and antitumor agents ll-e33288 -i and ll-e33288-br, with processes and intermediates for producing said agents

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 19980307

Year of fee payment: 9

B1PR Patent granted
PBON Lapse due to non-payment of renewal fee

Effective date: 19990308