AU1214892A - Amide-chelates, their metal complexes as well as their use in diagnosis and treatment - Google Patents
Amide-chelates, their metal complexes as well as their use in diagnosis and treatmentInfo
- Publication number
- AU1214892A AU1214892A AU12148/92A AU1214892A AU1214892A AU 1214892 A AU1214892 A AU 1214892A AU 12148/92 A AU12148/92 A AU 12148/92A AU 1214892 A AU1214892 A AU 1214892A AU 1214892 A AU1214892 A AU 1214892A
- Authority
- AU
- Australia
- Prior art keywords
- chelates
- diagnosis
- amide
- treatment
- well
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6887—Antibody-chelate conjugates using chelates for therapeutic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
- C07C331/16—Isothiocyanates
- C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4107571A DE4107571A1 (en) | 1991-03-07 | 1991-03-07 | AMID CHELATES, THEIR METAL COMPLEXES AND THEIR USE IN DIAGNOSTICS AND THERAPY |
DE4107571 | 1991-03-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU1214892A true AU1214892A (en) | 1992-09-10 |
Family
ID=6426850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU12148/92A Abandoned AU1214892A (en) | 1991-03-07 | 1992-03-06 | Amide-chelates, their metal complexes as well as their use in diagnosis and treatment |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0502595A3 (en) |
JP (1) | JPH06100519A (en) |
AU (1) | AU1214892A (en) |
CA (1) | CA2062454A1 (en) |
DE (1) | DE4107571A1 (en) |
IE (1) | IE920761A1 (en) |
PT (1) | PT100200A (en) |
ZA (1) | ZA921716B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5651954A (en) * | 1994-01-12 | 1997-07-29 | Bracco International B.V. | Method of using hydrazone containing ligands and metal complexes thereof |
US5808091A (en) * | 1991-10-29 | 1998-09-15 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia localizing moiety |
US6699458B2 (en) | 1991-10-29 | 2004-03-02 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia-localizing moiety |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3953509B2 (en) * | 1992-10-08 | 2007-08-08 | ジーイー・ヘルスケア・リミテッド | Metal oxime chelates used as radiopharmaceuticals |
US5608110A (en) * | 1993-06-15 | 1997-03-04 | Bracco International B.V. | Heteroatom-bearing ligands and metal complexes thereof |
US6613508B1 (en) | 1996-01-23 | 2003-09-02 | Qiagen Genomics, Inc. | Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques |
US6027890A (en) * | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
US6312893B1 (en) | 1996-01-23 | 2001-11-06 | Qiagen Genomics, Inc. | Methods and compositions for determining the sequence of nucleic acid molecules |
KR100675356B1 (en) * | 2005-04-29 | 2007-02-01 | 경희대학교 산학협력단 | Chelating agent comprising novel amide compound used in metal-extracting using supercritical or liquid state fluid, metal-extracting method and metal-extracting system using said chelating agent |
US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1243329A (en) * | 1985-03-11 | 1988-10-18 | Amersham Int Plc | Complexes of technetium-99m with propylene amine oximes |
US4746505A (en) * | 1985-04-26 | 1988-05-24 | President And Fellows Of Harvard College | Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands |
-
1991
- 1991-03-07 DE DE4107571A patent/DE4107571A1/en not_active Withdrawn
-
1992
- 1992-03-05 JP JP4048718A patent/JPH06100519A/en active Pending
- 1992-03-05 EP EP19920250052 patent/EP0502595A3/en not_active Withdrawn
- 1992-03-05 PT PT100200A patent/PT100200A/en not_active Application Discontinuation
- 1992-03-06 AU AU12148/92A patent/AU1214892A/en not_active Abandoned
- 1992-03-06 ZA ZA921716A patent/ZA921716B/en unknown
- 1992-03-06 CA CA002062454A patent/CA2062454A1/en not_active Abandoned
- 1992-03-09 IE IE076192A patent/IE920761A1/en not_active Application Discontinuation
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5808091A (en) * | 1991-10-29 | 1998-09-15 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia localizing moiety |
US6184361B1 (en) | 1991-10-29 | 2001-02-06 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia-localizing moiety |
US6699458B2 (en) | 1991-10-29 | 2004-03-02 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia-localizing moiety |
US6958141B2 (en) | 1991-10-29 | 2005-10-25 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia-localizing moiety |
US5651954A (en) * | 1994-01-12 | 1997-07-29 | Bracco International B.V. | Method of using hydrazone containing ligands and metal complexes thereof |
US5663307A (en) * | 1994-01-12 | 1997-09-02 | Bracco International B.V. | Hydrazone containing ligands and metal complexes thereof |
US6660246B1 (en) | 1994-01-12 | 2003-12-09 | Bracco International, Bv | Ligands and metal complexes thereof |
Also Published As
Publication number | Publication date |
---|---|
PT100200A (en) | 1993-05-31 |
ZA921716B (en) | 1992-11-25 |
EP0502595A2 (en) | 1992-09-09 |
EP0502595A3 (en) | 1993-08-11 |
IE920761A1 (en) | 1992-09-09 |
CA2062454A1 (en) | 1992-09-08 |
JPH06100519A (en) | 1994-04-12 |
DE4107571A1 (en) | 1992-11-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU4254696A (en) | Novel substituted dtpa derivatives, their metal complexes, pharmaceutical compositions containing these complexes and their use in diagnosis and therapy | |
HK1010484A1 (en) | Pharmaceutical composition for use in treatment ofdiabetes. | |
AU8487191A (en) | 2-aminopyrimidine-4-caroxamide derivatives, their preparation and their use in therapy | |
AU1180795A (en) | Novel palladium complexes and methods for using same in the treatment of tumors and psoriasis | |
EP0612513A3 (en) | External skin treatment composition. | |
HK1001286A1 (en) | Benzopyrans and their use as therapeutic agents. | |
AU1214892A (en) | Amide-chelates, their metal complexes as well as their use in diagnosis and treatment | |
AU1214792A (en) | Chelates, their metal complexes as well as their use in diagnosis and treatment | |
ZA925892B (en) | Organic nitrates, processes for their preparation and their use in the treatment of cardiovascular diseases. | |
IL109437A0 (en) | 2-Amino-4-quinolyldihydropyridines, processes for their preparation and their use | |
EP0706396A4 (en) | 1,2,3,4-tetrahydroquinoline-2,3,4-trione-3 or 4-oximes and use | |
ZA982136B (en) | Novel carboxylic acid derivatives, their preparation and use in treating cancer. | |
ZA922952B (en) | 2-aminopyrimidine-4-carboxyamide derivatives,their preparation and their application in therapy | |
AU1807492A (en) | New hetaryloxy-beta-carbolines, their production and use in pharmaceutical agents | |
IL111817A0 (en) | Halogen-containing metal complexes, diagnostic agents containing the same and processes for the preparation thereof | |
EP0446877A3 (en) | Triazoles, their production and use | |
AU1850092A (en) | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | |
AU4674596A (en) | Complexes, processes for their preparation and their use | |
AU1807097A (en) | 1:2 chromium complexes, their production and use | |
EP0442086A3 (en) | Graftcopolymers, their preparation and their use | |
AU8174691A (en) | Reducing chelating agents, their technetium and rhenium complexes, process for their production as well as their use in diagnosis and treatment | |
AU5975094A (en) | 1,2,4-triazinone derivatives and their use in therapy | |
GB9300912D0 (en) | Coordination complexes,preparation and use | |
HU9600660D0 (en) | Butenol-triazolyl derivatives, their manufacture and use as microbicides | |
EP0583698A3 (en) | Deoxycyclitol derivatives, process for their preparation and their use in medicaments. |