IE38383B1 - Doxycline parenteral composition - Google Patents
Doxycline parenteral compositionInfo
- Publication number
- IE38383B1 IE38383B1 IE1845/73A IE184573A IE38383B1 IE 38383 B1 IE38383 B1 IE 38383B1 IE 1845/73 A IE1845/73 A IE 1845/73A IE 184573 A IE184573 A IE 184573A IE 38383 B1 IE38383 B1 IE 38383B1
- Authority
- IE
- Ireland
- Prior art keywords
- salt
- doxycycline
- composition
- water
- ascorbate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1350196 Doxycycline parenteral composition PFIZER Inc 27 Dec 1972 [26 Oct 1972] 59710/72 Heading A5B Aqueous pharmaceutical compositions for parenteral administration comprise a solution in water of from 1 to 10% by weight of a pharmaceutically acceptable acid addition salt of doxycycline, together with at least 3 molar proportions of a water-soluble alkali metal phosphate salt, and at least 3 molar proportions of a pharmaceutically acceptable watersoluble magnesium salt, said composition having a pH value in the range of from 1.0 to 3.5 The doxycycline acid addition salt may be the hydrochloride, hydrochloride hemiethanolate hemihydrate, hydrobromide, sulphate, nitrate, ascorbate, citrate, gluconate, lactate, isonicotinate, gentisinate, pantothenate, salicylate, glucuronate, formate, or glutamate. The alkali metal phosphate salt may be sodium or potassium orthophosphate, metaphosphate, pyrophosphate, tripolyphosphate or hexametaphosphate and the magnesium salt may be magnesium chloride, glyconate, oxide, ascorbate or lactate. The pH value may be adjusted by ascorbic, tartaric, gluconic, glucuronic, citric, gentisic, isonicotinic or glutamic acid. The composition may also contain a water-soluble local anaesthetic such as procaine and lidocaine hydrochlorides.
[GB1350196A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30123672A | 1972-10-26 | 1972-10-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38383L IE38383L (en) | 1974-04-26 |
| IE38383B1 true IE38383B1 (en) | 1978-03-01 |
Family
ID=23162536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1845/73A IE38383B1 (en) | 1972-10-26 | 1973-10-16 | Doxycline parenteral composition |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS531815B2 (en) |
| AR (1) | AR200582A1 (en) |
| BE (1) | BE806261A (en) |
| CA (1) | CA1005760A (en) |
| CH (1) | CH583563A5 (en) |
| DE (1) | DE2352910A1 (en) |
| DK (1) | DK133084C (en) |
| FI (1) | FI52269B (en) |
| FR (1) | FR2204402B1 (en) |
| GB (1) | GB1350196A (en) |
| IE (1) | IE38383B1 (en) |
| KE (1) | KE2568A (en) |
| MY (1) | MY7500201A (en) |
| NL (1) | NL162836C (en) |
| PH (1) | PH9547A (en) |
| SE (1) | SE411424B (en) |
| ZA (1) | ZA738187B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0052404B1 (en) * | 1980-11-19 | 1987-05-27 | THE PROCTER & GAMBLE COMPANY | Non-yellowing topical pharmaceutical composition |
| US5124317A (en) * | 1985-08-02 | 1992-06-23 | Farmitalia Carlo Erba S.P.A. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
| US5977082A (en) | 1985-08-02 | 1999-11-02 | Pharmacia & Upjohn Company | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
| CN115844842A (en) * | 2022-12-28 | 2023-03-28 | 江西省保灵动物保健品有限公司 | Doxycycline hydrochloride tablet and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1767891C3 (en) * | 1968-06-28 | 1980-10-30 | Pfizer | Process for the preparation of aqueous medicinal solutions for parenteral, peroral and local use containing a tetracycline derivative |
| ES396132A1 (en) * | 1970-10-30 | 1972-12-01 | Villax | Complexes of a-6-deoxy-5-hydroxy tetracycline and their preparation |
-
1972
- 1972-12-27 GB GB5971072A patent/GB1350196A/en not_active Expired
-
1973
- 1973-10-16 IE IE1845/73A patent/IE38383B1/en unknown
- 1973-10-16 CA CA183,513A patent/CA1005760A/en not_active Expired
- 1973-10-19 BE BE1005441A patent/BE806261A/en not_active IP Right Cessation
- 1973-10-19 FR FR7337347A patent/FR2204402B1/fr not_active Expired
- 1973-10-22 DE DE19732352910 patent/DE2352910A1/en not_active Ceased
- 1973-10-22 PH PH15133*UA patent/PH9547A/en unknown
- 1973-10-23 CH CH1495773A patent/CH583563A5/xx not_active IP Right Cessation
- 1973-10-23 ZA ZA738187A patent/ZA738187B/en unknown
- 1973-10-24 NL NL7314596.A patent/NL162836C/en not_active IP Right Cessation
- 1973-10-24 FI FI3299/73A patent/FI52269B/fi active
- 1973-10-25 SE SE7314529A patent/SE411424B/en unknown
- 1973-10-25 DK DK578073A patent/DK133084C/en active
- 1973-10-25 JP JP11949073A patent/JPS531815B2/ja not_active Expired
- 1973-10-25 AR AR250701A patent/AR200582A1/en active
-
1975
- 1975-09-15 KE KE2568*UA patent/KE2568A/en unknown
- 1975-12-30 MY MY201/75A patent/MY7500201A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH9547A (en) | 1976-01-16 |
| AU6158973A (en) | 1975-04-24 |
| JPS4980226A (en) | 1974-08-02 |
| CA1005760A (en) | 1977-02-22 |
| ZA738187B (en) | 1974-11-27 |
| FR2204402A1 (en) | 1974-05-24 |
| IE38383L (en) | 1974-04-26 |
| BE806261A (en) | 1974-04-19 |
| CH583563A5 (en) | 1977-01-14 |
| DE2352910A1 (en) | 1974-05-09 |
| AR200582A1 (en) | 1974-11-22 |
| FR2204402B1 (en) | 1976-08-13 |
| MY7500201A (en) | 1975-12-31 |
| SE411424B (en) | 1979-12-27 |
| NL162836C (en) | 1980-07-15 |
| DK133084B (en) | 1976-03-22 |
| KE2568A (en) | 1975-09-26 |
| GB1350196A (en) | 1974-04-18 |
| JPS531815B2 (en) | 1978-01-23 |
| FI52269B (en) | 1977-05-02 |
| NL7314596A (en) | 1974-05-01 |
| NL162836B (en) | 1980-02-15 |
| DK133084C (en) | 1976-08-16 |
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