IE38383L - Doxycycline parenteral composition - Google Patents

Doxycycline parenteral composition

Info

Publication number
IE38383L
IE38383L IE731845A IE184573A IE38383L IE 38383 L IE38383 L IE 38383L IE 731845 A IE731845 A IE 731845A IE 184573 A IE184573 A IE 184573A IE 38383 L IE38383 L IE 38383L
Authority
IE
Ireland
Prior art keywords
doxycycline
salt
composition
water
ascorbate
Prior art date
Application number
IE731845A
Other versions
IE38383B1 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IE38383L publication Critical patent/IE38383L/en
Publication of IE38383B1 publication Critical patent/IE38383B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Abstract

1350196 Doxycycline parenteral composition PFIZER Inc 27 Dec 1972 [26 Oct 1972] 59710/72 Heading A5B Aqueous pharmaceutical compositions for parenteral administration comprise a solution in water of from 1 to 10% by weight of a pharmaceutically acceptable acid addition salt of doxycycline, together with at least 3 molar proportions of a water-soluble alkali metal phosphate salt, and at least 3 molar proportions of a pharmaceutically acceptable watersoluble magnesium salt, said composition having a pH value in the range of from 1.0 to 3.5 The doxycycline acid addition salt may be the hydrochloride, hydrochloride hemiethanolate hemihydrate, hydrobromide, sulphate, nitrate, ascorbate, citrate, gluconate, lactate, isonicotinate, gentisinate, pantothenate, salicylate, glucuronate, formate, or glutamate. The alkali metal phosphate salt may be sodium or potassium orthophosphate, metaphosphate, pyrophosphate, tripolyphosphate or hexametaphosphate and the magnesium salt may be magnesium chloride, glyconate, oxide, ascorbate or lactate. The pH value may be adjusted by ascorbic, tartaric, gluconic, glucuronic, citric, gentisic, isonicotinic or glutamic acid. The composition may also contain a water-soluble local anaesthetic such as procaine and lidocaine hydrochlorides. [GB1350196A]
IE1845/73A 1972-10-26 1973-10-16 Doxycline parenteral composition IE38383B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30123672A 1972-10-26 1972-10-26

Publications (2)

Publication Number Publication Date
IE38383L true IE38383L (en) 1974-04-26
IE38383B1 IE38383B1 (en) 1978-03-01

Family

ID=23162536

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1845/73A IE38383B1 (en) 1972-10-26 1973-10-16 Doxycline parenteral composition

Country Status (17)

Country Link
JP (1) JPS531815B2 (en)
AR (1) AR200582A1 (en)
BE (1) BE806261A (en)
CA (1) CA1005760A (en)
CH (1) CH583563A5 (en)
DE (1) DE2352910A1 (en)
DK (1) DK133084C (en)
FI (1) FI52269B (en)
FR (1) FR2204402B1 (en)
GB (1) GB1350196A (en)
IE (1) IE38383B1 (en)
KE (1) KE2568A (en)
MY (1) MY7500201A (en)
NL (1) NL162836C (en)
PH (1) PH9547A (en)
SE (1) SE411424B (en)
ZA (1) ZA738187B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3176215D1 (en) * 1980-11-19 1987-07-02 Procter & Gamble Non-yellowing topical pharmaceutical composition
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767891C3 (en) * 1968-06-28 1980-10-30 Pfizer Process for the preparation of aqueous medicinal solutions for parenteral, peroral and local use containing a tetracycline derivative
ES396132A1 (en) * 1970-10-30 1972-12-01 Villax Complexes of a-6-deoxy-5-hydroxy tetracycline and their preparation

Also Published As

Publication number Publication date
IE38383B1 (en) 1978-03-01
NL7314596A (en) 1974-05-01
ZA738187B (en) 1974-11-27
FR2204402A1 (en) 1974-05-24
NL162836C (en) 1980-07-15
AU6158973A (en) 1975-04-24
SE411424B (en) 1979-12-27
DK133084C (en) 1976-08-16
AR200582A1 (en) 1974-11-22
MY7500201A (en) 1975-12-31
DE2352910A1 (en) 1974-05-09
FR2204402B1 (en) 1976-08-13
BE806261A (en) 1974-04-19
FI52269B (en) 1977-05-02
KE2568A (en) 1975-09-26
NL162836B (en) 1980-02-15
JPS4980226A (en) 1974-08-02
CH583563A5 (en) 1977-01-14
DK133084B (en) 1976-03-22
PH9547A (en) 1976-01-16
GB1350196A (en) 1974-04-18
JPS531815B2 (en) 1978-01-23
CA1005760A (en) 1977-02-22

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