SI2855480T1 - Pteridini kot fgfr inhibitorji - Google Patents

Pteridini kot fgfr inhibitorji

Info

Publication number
SI2855480T1
SI2855480T1 SI201331519T SI201331519T SI2855480T1 SI 2855480 T1 SI2855480 T1 SI 2855480T1 SI 201331519 T SI201331519 T SI 201331519T SI 201331519 T SI201331519 T SI 201331519T SI 2855480 T1 SI2855480 T1 SI 2855480T1
Authority
SI
Slovenia
Prior art keywords
pteridines
fgfr inhibitors
fgfr
inhibitors
Prior art date
Application number
SI201331519T
Other languages
English (en)
Inventor
Gordon Saxty
Christopher Charles Frederick Hamlett
Valerio Berdini
Christopher William Murray
Patrick Rene Angibaud
Olivier Alexis Georges Querolle
Virginie Sophie Poncelet
Original Assignee
Astex Therapeutics Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astex Therapeutics Ltd. filed Critical Astex Therapeutics Ltd.
Publication of SI2855480T1 publication Critical patent/SI2855480T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI201331519T 2012-05-30 2013-05-30 Pteridini kot fgfr inhibitorji SI2855480T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261653081P 2012-05-30 2012-05-30
GBGB1209613.7A GB201209613D0 (en) 2012-05-30 2012-05-30 New compounds
US201361782233P 2013-03-14 2013-03-14
PCT/GB2013/051427 WO2013179033A1 (en) 2012-05-30 2013-05-30 Pteridines as fgfr inhibitors
EP13731850.7A EP2855480B1 (en) 2012-05-30 2013-05-30 Pteridines as fgfr inhibitors

Publications (1)

Publication Number Publication Date
SI2855480T1 true SI2855480T1 (sl) 2019-09-30

Family

ID=46546195

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201331519T SI2855480T1 (sl) 2012-05-30 2013-05-30 Pteridini kot fgfr inhibitorji

Country Status (19)

Country Link
US (2) US9447098B2 (sl)
EP (1) EP2855480B1 (sl)
JP (1) JP6363068B2 (sl)
KR (1) KR102149759B1 (sl)
CN (1) CN104507944B (sl)
AU (1) AU2013269316C1 (sl)
BR (1) BR112014029709B1 (sl)
CA (1) CA2874967C (sl)
DK (1) DK2855480T3 (sl)
ES (1) ES2739348T3 (sl)
GB (1) GB201209613D0 (sl)
HR (1) HRP20191202T1 (sl)
HU (1) HUE045663T2 (sl)
IN (1) IN2014MN02069A (sl)
LT (1) LT2855480T (sl)
MX (1) MX359418B (sl)
RU (1) RU2702906C2 (sl)
SI (1) SI2855480T1 (sl)
WO (1) WO2013179033A1 (sl)

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GB201020179D0 (en) 2010-11-29 2011-01-12 Astex Therapeutics Ltd New compounds
GB201118652D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118654D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118656D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118675D0 (en) 2011-10-28 2011-12-14 Astex Therapeutics Ltd New compounds
GB201209609D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201209613D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201307577D0 (en) 2013-04-26 2013-06-12 Astex Therapeutics Ltd New compounds
JO3512B1 (ar) 2014-03-26 2020-07-05 Astex Therapeutics Ltd مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
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